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Items: 1 to 50 of 79

1.

Capturing 5' and 3' native ends of mRNAs concurrently with Akron sequencing.

Ibrahim F, Mourelatos Z.

Nat Protoc. 2019 May;14(5):1578-1602. doi: 10.1038/s41596-019-0151-9. Epub 2019 Apr 10.

PMID:
30971782
2.

Regulation of gene expression by miR-144/451 during mouse erythropoiesis.

Xu P, Palmer LE, Lechauve C, Zhao G, Yao Y, Luan J, Vourekas A, Tan H, Peng J, Schuetz JD, Mourelatos Z, Wu G, Weiss MJ, Paralkar VR.

Blood. 2019 Jun 6;133(23):2518-2528. doi: 10.1182/blood.2018854604. Epub 2019 Apr 10.

PMID:
30971389
3.

Crystallization-sapphire-derived-fiber-based Fabry-Perot interferometer for refractive index and high-temperature measurement.

Zhang P, Zhang L, Mourelatos ZP, Wang Z.

Appl Opt. 2018 Oct 20;57(30):9016-9021. doi: 10.1364/AO.57.009016.

PMID:
30461889
4.

Set Phasers to Cleave: PIWI Cleavage Directs All piRNA Biogenesis.

Vourekas A, Mourelatos Z.

Mol Cell. 2018 Sep 6;71(5):651-652. doi: 10.1016/j.molcel.2018.08.035.

5.

Ribothrypsis, a novel process of canonical mRNA decay, mediates ribosome-phased mRNA endonucleolysis.

Ibrahim F, Maragkakis M, Alexiou P, Mourelatos Z.

Nat Struct Mol Biol. 2018 Apr;25(4):302-310. doi: 10.1038/s41594-018-0042-8. Epub 2018 Mar 5.

6.

High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model.

Richman SA, Nunez-Cruz S, Moghimi B, Li LZ, Gershenson ZT, Mourelatos Z, Barrett DM, Grupp SA, Milone MC.

Cancer Immunol Res. 2018 Jan;6(1):36-46. doi: 10.1158/2326-6066.CIR-17-0211. Epub 2017 Nov 27.

7.

cCLIP-Seq: Retrieval of Chimeric Reads from HITS-CLIP (CLIP-Seq) Libraries.

Alexiou P, Maragkakis M, Mourelatos Z, Vourekas A.

Methods Mol Biol. 2018;1680:87-100. doi: 10.1007/978-1-4939-7339-2_6.

PMID:
29030843
8.

Kc167, a widely used Drosophila cell line, contains an active primary piRNA pathway.

Vrettos N, Maragkakis M, Alexiou P, Mourelatos Z.

RNA. 2017 Jan;23(1):108-118. Epub 2016 Oct 27.

9.

Sequence-dependent but not sequence-specific piRNA adhesion traps mRNAs to the germ plasm.

Vourekas A, Alexiou P, Vrettos N, Maragkakis M, Mourelatos Z.

Nature. 2016 Mar 17;531(7594):390-394. doi: 10.1038/nature17150. Epub 2016 Mar 7.

10.

CLIPSeqTools--a novel bioinformatics CLIP-seq analysis suite.

Maragkakis M, Alexiou P, Nakaya T, Mourelatos Z.

RNA. 2016 Jan;22(1):1-9. doi: 10.1261/rna.052167.115. Epub 2015 Nov 17.

11.

The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing.

Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ.

Genes Dev. 2015 Mar 15;29(6):617-29. doi: 10.1101/gad.254631.114. Epub 2015 Mar 11.

12.

Native gel analysis for mammalian microRNPs assembled from pre-microRNAs.

Liu X, Mourelatos Z.

Methods Mol Biol. 2015;1206:39-51. doi: 10.1007/978-1-4939-1369-5_4.

PMID:
25240885
13.

A MicroRNA precursor surveillance system in quality control of MicroRNA synthesis.

Liu X, Zheng Q, Vrettos N, Maragkakis M, Alexiou P, Gregory BD, Mourelatos Z.

Mol Cell. 2014 Sep 18;55(6):868-879. doi: 10.1016/j.molcel.2014.07.017. Epub 2014 Aug 28.

14.

HITS-CLIP (CLIP-Seq) for mouse Piwi proteins.

Vourekas A, Mourelatos Z.

Methods Mol Biol. 2014;1093:73-95. doi: 10.1007/978-1-62703-694-8_7.

PMID:
24178558
15.

Mitochondrial protein BmPAPI modulates the length of mature piRNAs.

Honda S, Kirino Y, Maragkakis M, Alexiou P, Ohtaki A, Murali R, Mourelatos Z, Kirino Y.

RNA. 2013 Oct;19(10):1405-18. doi: 10.1261/rna.040428.113. Epub 2013 Aug 22.

16.

Identification of in vivo, conserved, TAF15 RNA binding sites reveals the impact of TAF15 on the neuronal transcriptome.

Ibrahim F, Maragkakis M, Alexiou P, Maronski MA, Dichter MA, Mourelatos Z.

Cell Rep. 2013 Feb 21;3(2):301-8. doi: 10.1016/j.celrep.2013.01.021. Epub 2013 Feb 14.

17.

FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns.

Nakaya T, Alexiou P, Maragkakis M, Chang A, Mourelatos Z.

RNA. 2013 Apr;19(4):498-509. doi: 10.1261/rna.037804.112. Epub 2013 Feb 6.

18.

Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis.

Vourekas A, Zheng Q, Alexiou P, Maragkakis M, Kirino Y, Gregory BD, Mourelatos Z.

Nat Struct Mol Biol. 2012 Aug;19(8):773-81. doi: 10.1038/nsmb.2347. Epub 2012 Jul 29.

19.

Precursor microRNA-programmed silencing complex assembly pathways in mammals.

Liu X, Jin DY, McManus MT, Mourelatos Z.

Mol Cell. 2012 May 25;46(4):507-17. doi: 10.1016/j.molcel.2012.03.010. Epub 2012 Apr 12.

20.

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis.

Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Mojsilovic-Petrovic J, Panossian S, Kim CE, Frackelton EC, Solski JA, Williams KL, Clay-Falcone D, Elman L, McCluskey L, Greene R, Hakonarson H, Kalb RG, Lee VM, Trojanowski JQ, Nicholson GA, Blair IP, Bonini NM, Van Deerlin VM, Mourelatos Z, Shorter J, Gitler AD.

Hum Mol Genet. 2012 Jul 1;21(13):2899-911. doi: 10.1093/hmg/dds116. Epub 2012 Mar 27.

21.

MiRNA-9 and MiRNA-200a distinguish hemangioblastomas from metastatic clear cell renal cell carcinomas in the CNS.

Venneti S, Boateng LA, Friedman JR, Baldwin DA, Tobias JW, Judkins AR, Mourelatos Z, Lal P.

Brain Pathol. 2012 Jul;22(4):522-9. doi: 10.1111/j.1750-3639.2011.00551.x. Epub 2011 Dec 9.

PMID:
22082152
22.

A yeast functional screen predicts new candidate ALS disease genes.

Couthouis J, Hart MP, Shorter J, DeJesus-Hernandez M, Erion R, Oristano R, Liu AX, Ramos D, Jethava N, Hosangadi D, Epstein J, Chiang A, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Solski JA, Williams KL, Mojsilovic-Petrovic J, Ingre C, Boylan K, Graff-Radford NR, Dickson DW, Clay-Falcone D, Elman L, McCluskey L, Greene R, Kalb RG, Lee VM, Trojanowski JQ, Ludolph A, Robberecht W, Andersen PM, Nicholson GA, Blair IP, King OD, Bonini NM, Van Deerlin V, Rademakers R, Mourelatos Z, Gitler AD.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):20881-90. doi: 10.1073/pnas.1109434108. Epub 2011 Nov 7.

23.

RNA dysregulation in diseases of motor neurons.

Ibrahim F, Nakaya T, Mourelatos Z.

Annu Rev Pathol. 2012;7:323-52. doi: 10.1146/annurev-pathol-011110-130307. Epub 2011 Oct 24. Review.

PMID:
22035195
24.

Immunoprecipitation of piRNPs and directional, next generation sequencing of piRNAs.

Kirino Y, Vourekas A, Khandros E, Mourelatos Z.

Methods Mol Biol. 2011;725:281-93. doi: 10.1007/978-1-61779-046-1_18.

PMID:
21528460
25.

Asymmetric bilateral demyelinating optic neuropathy from tacrolimus toxicity.

Venneti S, Moss HE, Levin MH, Vagefi MR, Brozena SC, Pruitt AA, Mourelatos Z, Trojanowski JQ, Galetta SL, Balcer LJ.

J Neurol Sci. 2011 Feb 15;301(1-2):112-5. doi: 10.1016/j.jns.2010.10.014. Epub 2010 Nov 26.

PMID:
21112060
26.

Elective affinities: a Tudor-Aubergine tale of germline partnership.

Vourekas A, Kirino Y, Mourelatos Z.

Genes Dev. 2010 Sep 15;24(18):1963-6. doi: 10.1101/gad.1977010.

27.

Rapid in situ codetection of noncoding RNAs and proteins in cells and formalin-fixed paraffin-embedded tissue sections without protease treatment.

de Planell-Saguer M, Rodicio MC, Mourelatos Z.

Nat Protoc. 2010 Jun;5(6):1061-73. doi: 10.1038/nprot.2010.62. Epub 2010 May 20.

PMID:
20539282
28.

High-throughput experimental studies to identify miRNA targets directly, with special focus on the mammalian brain.

Nelson PT, Kiriakidou M, Mourelatos Z, Tan GS, Jennings MH, Xie K, Wang WX.

Brain Res. 2010 Jun 18;1338:122-30. doi: 10.1016/j.brainres.2010.03.108. Epub 2010 Apr 7. Review.

29.

Arginine methylation of vasa protein is conserved across phyla.

Kirino Y, Vourekas A, Kim N, de Lima Alves F, Rappsilber J, Klein PS, Jongens TA, Mourelatos Z.

J Biol Chem. 2010 Mar 12;285(11):8148-54. doi: 10.1074/jbc.M109.089821. Epub 2010 Jan 15.

30.

Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization.

Kirino Y, Vourekas A, Sayed N, de Lima Alves F, Thomson T, Lasko P, Rappsilber J, Jongens TA, Mourelatos Z.

RNA. 2010 Jan;16(1):70-8. doi: 10.1261/rna.1869710. Epub 2009 Nov 19.

31.

Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell.

Sotiropoulou G, Pampalakis G, Lianidou E, Mourelatos Z.

RNA. 2009 Aug;15(8):1443-61. doi: 10.1261/rna.1534709. Epub 2009 Jun 26. Review.

32.

Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability.

Kirino Y, Kim N, de Planell-Saguer M, Khandros E, Chiorean S, Klein PS, Rigoutsos I, Jongens TA, Mourelatos Z.

Nat Cell Biol. 2009 May;11(5):652-8. doi: 10.1038/ncb1872. Epub 2009 Apr 19.

33.

Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.

de Planell-Saguer M, Schroeder DG, Rodicio MC, Cox GA, Mourelatos Z.

Hum Mol Genet. 2009 Jun 15;18(12):2115-26. doi: 10.1093/hmg/ddp134. Epub 2009 Mar 19.

34.

Small RNAs: The seeds of silence.

Mourelatos Z.

Nature. 2008 Sep 4;455(7209):44-5. doi: 10.1038/455044a. No abstract available.

PMID:
18769430
35.

Site-specific crosslinking of human microRNPs to RNA targets.

Kirino Y, Mourelatos Z.

RNA. 2008 Oct;14(10):2254-9. doi: 10.1261/rna.1133808. Epub 2008 Aug 21.

36.

MicroRNAs: biogenesis and molecular functions.

Liu X, Fortin K, Mourelatos Z.

Brain Pathol. 2008 Jan;18(1):113-21. doi: 10.1111/j.1750-3639.2007.00121.x. Review.

PMID:
18226106
37.

MicroRNAs: biology and roles in neurodegeneration and brain tumours. Introduction and historical background.

Mourelatos Z.

Brain Pathol. 2008 Jan;18(1):110-2. doi: 10.1111/j.1750-3639.2007.00118.x. Review. No abstract available.

PMID:
18226105
38.

2'-O-methyl modification in mouse piRNAs and its methylase.

Kirino Y, Mourelatos Z.

Nucleic Acids Symp Ser (Oxf). 2007;(51):417-8.

PMID:
18029764
39.

Small regulatory RNAs: biogenesis & functions.

Mourelatos Z.

Nucleic Acids Symp Ser (Oxf). 2007;(51):105. No abstract available.

PMID:
18029608
40.

A novel monoclonal antibody against human Argonaute proteins reveals unexpected characteristics of miRNAs in human blood cells.

Nelson PT, De Planell-Saguer M, Lamprinaki S, Kiriakidou M, Zhang P, O'Doherty U, Mourelatos Z.

RNA. 2007 Oct;13(10):1787-92. Epub 2007 Aug 24.

41.

The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs.

Kirino Y, Mourelatos Z.

RNA. 2007 Sep;13(9):1397-401. Epub 2007 Jul 24.

42.

An mRNA m7G cap binding-like motif within human Ago2 represses translation.

Kiriakidou M, Tan GS, Lamprinaki S, De Planell-Saguer M, Nelson PT, Mourelatos Z.

Cell. 2007 Jun 15;129(6):1141-51. Epub 2007 May 24.

43.

Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.

Kirino Y, Mourelatos Z.

Nat Struct Mol Biol. 2007 Apr;14(4):347-8. Epub 2007 Mar 25.

PMID:
17384647
44.

Immunochemical characterization of polysaccharide antigens from six clinical strains of Enterococci.

Hsu CT, Ganong AL, Reinap B, Mourelatos Z, Huebner J, Wang JY.

BMC Microbiol. 2006 Jul 12;6:62.

45.

RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain.

Nelson PT, Baldwin DA, Kloosterman WP, Kauppinen S, Plasterk RH, Mourelatos Z.

RNA. 2006 Feb;12(2):187-91. Epub 2005 Dec 22.

46.

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA.

Maniataki E, Mourelatos Z.

Genes Dev. 2005 Dec 15;19(24):2979-90.

47.

Detection of microRNAs and assays to monitor microRNA activities in vivo and in vitro.

Kiriakidou M, Nelson P, Lamprinaki S, Sharma A, Mourelatos Z.

Methods Mol Biol. 2005;309:295-310. No abstract available.

PMID:
15990409
48.

Immunoprecipitation of microRNPs and directional cloning of microRNAs.

Maniataki E, De Planell Saguer MD, Mourelatos Z.

Methods Mol Biol. 2005;309:283-94. No abstract available.

PMID:
15990408
49.
50.

Microarray-based, high-throughput gene expression profiling of microRNAs.

Nelson PT, Baldwin DA, Scearce LM, Oberholtzer JC, Tobias JW, Mourelatos Z.

Nat Methods. 2004 Nov;1(2):155-61. Epub 2004 Oct 21.

PMID:
15782179

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