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Items: 11


Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics.

Weston M, Kaserer T, Wu A, Mouravlev A, Carpenter JC, Snowball A, Knauss S, von Schimmelmann M, During MJ, Lignani G, Schorge S, Young D, Kullmann DM, Lieb A.

Sci Adv. 2019 Apr 17;5(4):eaaw1567. doi: 10.1126/sciadv.aaw1567. eCollection 2019 Apr.


Astrocyte-selective AAV gene therapy through the endogenous GFAP promoter results in robust transduction in the rat spinal cord following injury.

Griffin JM, Fackelmeier B, Fong DM, Mouravlev A, Young D, O'Carroll SJ.

Gene Ther. 2019 May;26(5):198-210. doi: 10.1038/s41434-019-0075-6. Epub 2019 Apr 8.


Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer.

Mudannayake JM, Mouravlev A, Fong DM, Young D.

Mol Ther Methods Clin Dev. 2016 Nov 30;3:16075. eCollection 2016.


A novel bicistronic sensor vector for detecting caspase-3 activation.

Vagner T, Mouravlev A, Young D.

J Pharmacol Toxicol Methods. 2015 Mar-Apr;72:11-8. doi: 10.1016/j.vascn.2014.11.006. Epub 2014 Dec 4.


Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.

Young D, Fong DM, Lawlor PA, Wu A, Mouravlev A, McRae M, Glass M, Dragunow M, During MJ.

Gene Ther. 2014 Dec;21(12):1029-40. doi: 10.1038/gt.2014.82. Epub 2014 Sep 18.


Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina.

Charbel Issa P, De Silva SR, Lipinski DM, Singh MS, Mouravlev A, You Q, Barnard AR, Hankins MW, During MJ, Maclaren RE.

PLoS One. 2013 Apr 9;8(4):e60361. doi: 10.1371/journal.pone.0060361. Print 2013.


Nucleic Acid-Based Therapy Approaches for Huntington's Disease.

Vagner T, Young D, Mouravlev A.

Neurol Res Int. 2012;2012:358370. doi: 10.1155/2012/358370. Epub 2012 Jan 11.


Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.

Lawlor PA, Bland RJ, Mouravlev A, Young D, During MJ.

Mol Ther. 2009 Oct;17(10):1692-702. doi: 10.1038/mt.2009.170. Epub 2009 Jul 28.


Phosphorylation-dependent degradation of transgenic CREB protein initiated by heterodimerization.

Mouravlev A, Young D, During MJ.

Brain Res. 2007 Jan 26;1130(1):31-7. Epub 2006 Dec 13.


Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats.

Mouravlev A, Dunning J, Young D, During MJ.

Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4705-10. Epub 2006 Mar 14.


Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes.

Xu R, Janson CG, Mastakov M, Lawlor P, Young D, Mouravlev A, Fitzsimons H, Choi KL, Ma H, Dragunow M, Leone P, Chen Q, Dicker B, During MJ.

Gene Ther. 2001 Sep;8(17):1323-32.

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