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Vision using multiple distinct rod opsins in deep-sea fishes.

Musilova Z, Cortesi F, Matschiner M, Davies WIL, Patel JS, Stieb SM, de Busserolles F, Malmstrøm M, Tørresen OK, Brown CJ, Mountford JK, Hanel R, Stenkamp DL, Jakobsen KS, Carleton KL, Jentoft S, Marshall J, Salzburger W.

Science. 2019 May 10;364(6440):588-592. doi: 10.1126/science.aav4632.


Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation.

Trakarnsanga K, Ferguson D, Daniels DE, Griffiths RE, Wilson MC, Mordue KE, Gartner A, Andrienko TN, Calvert A, Condie A, McCahill A, Mountford JC, Toye AM, Anstee DJ, Frayne J.

Stem Cell Res Ther. 2019 Apr 29;10(1):130. doi: 10.1186/s13287-019-1231-z.


A report from a workshop of the International Stem Cell Banking Initiative, held in collaboration GAiT and the Harvard Stem Cell Institute, Boston 2017.

Kim JH, Alderton A, Benvenisty N, Brandsten C, Firpo M, Harrison PW, Kawamata S, Kawase E, Kurtz A, Loring JF, Ludwig T, Man J, Mountford JC, Turner ML, Oh S, da Veiga Pereira L, Pranke P, Sheldon M, Steeg R, Sullivan S, Yaffe M, Zhou Q, Stacey GN.

Stem Cells. 2019 Apr 25. doi: 10.1002/stem.3003. [Epub ahead of print]


Differential stability of variant OPN1LW gene transcripts in myopic patients.

Mountford JK, Davies WIL, Griffiths LR, Yazar S, Mackey DA, Hunt DM.

Mol Vis. 2019 Mar 17;25:183-193. eCollection 2019.


The Role of the Voltage-Gated Potassium Channel Proteins Kv8.2 and Kv2.1 in Vision and Retinal Disease: Insights from the Study of Mouse Gene Knock-Out Mutations.

Hart NS, Mountford JK, Voigt V, Fuller-Carter P, Barth M, Nerbonne JM, Hunt DM, Carvalho LS.

eNeuro. 2019 Feb 25;6(1). pii: ENEURO.0032-19.2019. doi: 10.1523/ENEURO.0032-19.2019. eCollection 2019 Jan-Feb.


Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.

Lopez-Yrigoyen M, Yang CT, Fidanza A, Cassetta L, Taylor AH, McCahill A, Sellink E, von Lindern M, van den Akker E, Mountford JC, Pollard JW, Forrester LM.

Nat Commun. 2019 Feb 20;10(1):881. doi: 10.1038/s41467-019-08705-0.


Quality control guidelines for clinical-grade human induced pluripotent stem cell lines.

Sullivan S, Stacey GN, Akazawa C, Aoyama N, Baptista R, Bedford P, Bennaceur Griscelli A, Chandra A, Elwood N, Girard M, Kawamata S, Hanatani T, Latsis T, Lin S, Ludwig TE, Malygina T, Mack A, Mountford JC, Noggle S, Pereira LV, Price J, Sheldon M, Srivastava A, Stachelscheid H, Velayudhan SR, Ward NJ, Turner ML, Barry J, Song J.

Regen Med. 2018 Oct;13(7):859-866. doi: 10.2217/rme-2018-0095. Epub 2018 Sep 12.


Robust Revascularization in Models of Limb Ischemia Using a Clinically Translatable Human Stem Cell-Derived Endothelial Cell Product.

MacAskill MG, Saif J, Condie A, Jansen MA, MacGillivray TJ, Tavares AAS, Fleisinger L, Spencer HL, Besnier M, Martin E, Biglino G, Newby DE, Hadoke PWF, Mountford JC, Emanueli C, Baker AH.

Mol Ther. 2018 Jul 5;26(7):1669-1684. doi: 10.1016/j.ymthe.2018.03.017. Epub 2018 Mar 28.


Ex-vivo expression of chemokine receptors on cells surrounding cutaneous nerves in patients with HIV-associated sensory neuropathy.

Mountford J, Octaviana F, Estiasari R, Setiawan DD, Ariyanto I, Lee S, Gaff J, Chew C, Jackaman C, Kamerman P, Cherry C, Price P.

AIDS. 2018 Feb 20;32(4):431-441. doi: 10.1097/QAD.0000000000001714.


Pushing the limits of photoreception in twilight conditions: The rod-like cone retina of the deep-sea pearlsides.

de Busserolles F, Cortesi F, Helvik JV, Davies WIL, Templin RM, Sullivan RKP, Michell CT, Mountford JK, Collin SP, Irigoien X, Kaartvedt S, Marshall J.

Sci Adv. 2017 Nov 8;3(11):eaao4709. doi: 10.1126/sciadv.aao4709. eCollection 2017 Nov.


Good Manufacturing Practice (GMP) Translation of Advanced Cellular Therapeutics: Lessons for the Manufacture of Erythrocytes as Medicinal Products.

McGowan NWA, Campbell JDM, Mountford JC.

Methods Mol Biol. 2018;1698:285-292. doi: 10.1007/978-1-4939-7428-3_18. Review.


PET Cell Tracking Using 18F-FLT is Not Limited by Local Reuptake of Free Radiotracer.

MacAskill MG, Tavares AS, Wu J, Lucatelli C, Mountford JC, Baker AH, Newby DE, Hadoke PW.

Sci Rep. 2017 Mar 13;7:44233. doi: 10.1038/srep44233.


Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.

Yang CT, Ma R, Axton RA, Jackson M, Taylor AH, Fidanza A, Marenah L, Frayne J, Mountford JC, Forrester LM.

Stem Cells. 2017 Apr;35(4):886-897. doi: 10.1002/stem.2562. Epub 2017 Jan 19.


Hamlyn R Brier (1911-2001).

Vincent SJ, Mountford JA.

Clin Exp Optom. 2017 Sep;100(5):541-544. doi: 10.1111/cxo.12503. Epub 2016 Dec 18. No abstract available.


High-Efficiency Serum-Free Feeder-Free Erythroid Differentiation of Human Pluripotent Stem Cells Using Small Molecules.

Olivier EN, Marenah L, McCahill A, Condie A, Cowan S, Mountford JC.

Stem Cells Transl Med. 2016 Oct;5(10):1394-1405. Epub 2016 Jul 8.


Visual pigments in a palaeognath bird, the emu Dromaius novaehollandiae: implications for spectral sensitivity and the origin of ultraviolet vision.

Hart NS, Mountford JK, Davies WI, Collin SP, Hunt DM.

Proc Biol Sci. 2016 Jul 13;283(1834). pii: 20161063. doi: 10.1098/rspb.2016.1063.


Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.

Jackson M, Ma R, Taylor AH, Axton RA, Easterbrook J, Kydonaki M, Olivier E, Marenah L, Stanley EG, Elefanty AG, Mountford JC, Forrester LM.

Stem Cells Transl Med. 2016 Aug;5(8):981-90. doi: 10.5966/sctm.2015-0324. Epub 2016 Jun 28.


From stoplight reports to time series: equipping boards and leadership teams to drive better decisions.

Mountford J, Wakefield D.

BMJ Qual Saf. 2017 Jan;26(1):9-11. doi: 10.1136/bmjqs-2016-005303. Epub 2016 Mar 31. No abstract available.


Combined deficiency of PI3KC2α and PI3KC2β reveals a nonredundant role for PI3KC2α in regulating mouse platelet structure and thrombus stability.

Petitjean C, Setiabakti NM, Mountford JK, Arthur JF, Ellis S, Hamilton JR.

Platelets. 2016 Jul;27(5):402-9. doi: 10.3109/09537104.2016.1145202. Epub 2016 Mar 4.


A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial Cells.

Boulberdaa M, Scott E, Ballantyne M, Garcia R, Descamps B, Angelini GD, Brittan M, Hunter A, McBride M, McClure J, Miano JM, Emanueli C, Mills NL, Mountford JC, Baker AH.

Mol Ther. 2016 May;24(5):978-90. doi: 10.1038/mt.2016.41. Epub 2016 Feb 22.


Circular RNA enrichment in platelets is a signature of transcriptome degradation.

Alhasan AA, Izuogu OG, Al-Balool HH, Steyn JS, Evans A, Colzani M, Ghevaert C, Mountford JC, Marenah L, Elliott DJ, Santibanez-Koref M, Jackson MS.

Blood. 2016 Mar 3;127(9):e1-e11. doi: 10.1182/blood-2015-06-649434. Epub 2015 Dec 10.


Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.

Garate Z, Quintana-Bustamante O, Crane AM, Olivier E, Poirot L, Galetto R, Kosinski P, Hill C, Kung C, Agirre X, Orman I, Cerrato L, Alberquilla O, Rodriguez-Fornes F, Fusaki N, Garcia-Sanchez F, Maia TM, Ribeiro ML, Sevilla J, Prosper F, Jin S, Mountford J, Guenechea G, Gouble A, Bueren JA, Davis BR, Segovia JC.

Stem Cell Reports. 2015 Dec 8;5(6):1053-1066. doi: 10.1016/j.stemcr.2015.10.002. Epub 2015 Nov 5.


Impact of a patient-specific co-designed COPD care scorecard on COPD care quality: a quasi-experimental study.

Roberts CM, Gungor G, Parker M, Craig J, Mountford J.

NPJ Prim Care Respir Med. 2015 Mar 26;25:15017. doi: 10.1038/npjpcrm.2015.17.


The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.

Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, Tønnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP.

Nat Commun. 2015 Mar 17;6:6535. doi: 10.1038/ncomms7535.


Don Noack: (1933-2012): a profile of a contact lens innovator and pioneer.

Mountford J.

Clin Exp Optom. 2015 Mar;98(2):194-6. doi: 10.1111/cxo.12256. No abstract available.


Reply to Letter: Incidence and outcome of in-hospital cardiac arrest in the United Kingdom Cardiac Arrest Audit--Can we clarify our purpose and shift the paradigm?

Hopkins C, Turkington P, Beckett D, Welch J, Hunter A, Keith I, Mountford J, Longmate A.

Resuscitation. 2015 Jan;86:e1. doi: 10.1016/j.resuscitation.2014.07.022. Epub 2014 Oct 18. No abstract available.


Understanding quality improvement at scale in general practice: a qualitative evaluation of a COPD improvement programme.

Marshall M, Mountford J, Gamet K, Gungor G, Burke C, Hudson R, Morris S, Patel N, Koczan P, Meaker R, Chantler C, Roberts CM.

Br J Gen Pract. 2014 Dec;64(629):e745-51. doi: 10.3399/bjgp14X682801.


Identifying viable regulatory and innovation pathways for regenerative medicine: a case study of cultured red blood cells.

Mittra J, Tait J, Mastroeni M, Turner ML, Mountford JC, Bruce K.

N Biotechnol. 2015 Jan 25;32(1):180-90. doi: 10.1016/j.nbt.2014.07.008. Epub 2014 Aug 2.


From harm to hope and purposeful action: what could we do after Francis?

Woodhead T, Lachman P, Mountford J, Botwinick L, Peden C, Stewart K.

BMJ Qual Saf. 2014 Aug;23(8):619-23. doi: 10.1136/bmjqs-2013-002581. Epub 2014 Jun 4.


Managing pulmonary nontuberculous mycobacterial infection. time for a patient-centered approach.

Satta G, McHugh TD, Mountford J, Abubakar I, Lipman M.

Ann Am Thorac Soc. 2014 Jan;11(1):117-21. doi: 10.1513/AnnalsATS.201308-278OT. Review.


More dialogue, more learning, more action.

Mountford J, Marshall M.

BMJ Qual Saf. 2014 Feb;23(2):89-91. doi: 10.1136/bmjqs-2013-002471. Epub 2013 Sep 30. No abstract available.


Impact on clinical and cost outcomes of a centralized approach to acute stroke care in London: a comparative effectiveness before and after model.

Hunter RM, Davie C, Rudd A, Thompson A, Walker H, Thomson N, Mountford J, Schwamm L, Deanfield J, Thompson K, Dewan B, Mistry M, Quoraishi S, Morris S.

PLoS One. 2013 Aug 1;8(8):e70420. doi: 10.1371/journal.pone.0070420. Print 2013.


MicroRNA regulation of endothelial homeostasis and commitment-implications for vascular regeneration strategies using stem cell therapies.

Scott E, Loya K, Mountford J, Milligan G, Baker AH.

Free Radic Biol Med. 2013 Sep;64:52-60. doi: 10.1016/j.freeradbiomed.2013.04.037. Epub 2013 May 9. Review.


Developing a science of improvement.

Marshall M, Mountford J.

J R Soc Med. 2013 Feb;106(2):45-50. doi: 10.1177/0141076812472622. No abstract available.


Human mesenchymal stem cells isolated from olfactory biopsies but not bone enhance CNS myelination in vitro.

Lindsay SL, Johnstone SA, Mountford JC, Sheikh S, Allan DB, Clark L, Barnett SC.

Glia. 2013 Mar;61(3):368-82. doi: 10.1002/glia.22440. Epub 2012 Dec 22.


HIECs: Stepping good practice up a gear.

Hudson R, Fowler C, Mountford J.

Health Serv J. 2012 Aug 23;122(6318):26-7. No abstract available.


PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome.

Terrin A, Monterisi S, Stangherlin A, Zoccarato A, Koschinski A, Surdo NC, Mongillo M, Sawa A, Jordanides NE, Mountford JC, Zaccolo M.

J Cell Biol. 2012 Aug 20;198(4):607-21. doi: 10.1083/jcb.201201059.


Derivation of vascular endothelial cells from human embryonic stem cells under GMP-compliant conditions: towards clinical studies in ischaemic disease.

Kaupisch A, Kennedy L, Stelmanis V, Tye B, Kane NM, Mountford JC, Courtney A, Baker AH.

J Cardiovasc Transl Res. 2012 Oct;5(5):605-17. Epub 2012 Aug 2.


What is a quality improvement project?

Gill D, Mountford J.

Br J Hosp Med (Lond). 2012 May;73(5):252-6.


Refocusing quality measurement to best support quality improvement: local ownership of quality measurement by clinicians.

Mountford J, Shojania KG.

BMJ Qual Saf. 2012 Jun;21(6):519-23. doi: 10.1136/bmjqs-2012-000859. Epub 2012 Mar 23. No abstract available.


Safety and efficacy of targeting platelet proteinase-activated receptors in combination with existing anti-platelet drugs as antithrombotics in mice.

Lee H, Sturgeon SA, Mountford JK, Jackson SP, Hamilton JR.

Br J Pharmacol. 2012 Aug;166(7):2188-97. doi: 10.1111/j.1476-5381.2012.01944.x.


Do fenestrations affect the performance of orthokeratology lenses?

Cho P, Chan B, Cheung SW, Mountford J.

Optom Vis Sci. 2012 Apr;89(4):401-10. doi: 10.1097/OPX.0b013e31824cb743.


Role of microRNAs 99b, 181a, and 181b in the differentiation of human embryonic stem cells to vascular endothelial cells.

Kane NM, Howard L, Descamps B, Meloni M, McClure J, Lu R, McCahill A, Breen C, Mackenzie RM, Delles C, Mountford JC, Milligan G, Emanueli C, Baker AH.

Stem Cells. 2012 Apr;30(4):643-54. doi: 10.1002/stem.1026.


Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells.

Yung S, Ledran M, Moreno-Gimeno I, Conesa A, Montaner D, Dopazo J, Dimmick I, Slater NJ, Marenah L, Real PJ, Paraskevopoulou I, Bisbal V, Burks D, Santibanez-Koref M, Moreno R, Mountford J, Menendez P, Armstrong L, Lako M.

Hum Mol Genet. 2011 Dec 15;20(24):4932-46. doi: 10.1093/hmg/ddr431. Epub 2011 Sep 21.


Investigation into omacetaxine solution stability for in vitro study.

Marenah L, Allan EK, Mountford JC, Holyoake TL, Jørgensen HG, Elliott MA.

Biomed Chromatogr. 2012 May;26(5):545-7. doi: 10.1002/bmc.1686. Epub 2011 Aug 9.


In vitro production of red blood cells.

Mountford JC, Turner M.

Transfus Apher Sci. 2011 Aug;45(1):85-9. doi: 10.1016/j.transci.2011.06.007. Epub 2011 Jul 1. Review.


A chance to optimise "value" in the NHS.

Fielden J, Mountford J.

BMJ. 2011 Jun 1;342:d3244. doi: 10.1136/bmj.d3244. No abstract available.


The Use of Modest Incentives to Boost Adoption of Safety Practices and Systems.

Meyer GS, Torchiana DF, Colton D, Mountford J, Mort E, Lenz S, Gagliano N, Immen E, Heffernan J.

In: Henriksen K, Battles JB, Keyes MA, Grady ML, editors. Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 3: Performance and Tools). Rockville (MD): Agency for Healthcare Research and Quality (US); 2008 Aug.


The impact of nitrogen deposition on acid grasslands in the Atlantic region of Europe.

Stevens CJ, Duprè C, Dorland E, Gaudnik C, Gowing DJ, Bleeker A, Diekmann M, Alard D, Bobbink R, Fowler D, Corcket E, Mountford JO, Vandvik V, Aarrestad PA, Muller S, Dise NB.

Environ Pollut. 2011 Oct;159(10):2243-50. doi: 10.1016/j.envpol.2010.11.026. Epub 2010 Dec 16.


Toward an outcomes-based health care system: a view from the United Kingdom.

Mountford J, Davie C.

JAMA. 2010 Dec 1;304(21):2407-8. doi: 10.1001/jama.2010.1751. No abstract available.


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