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Items: 29


Publisher Correction: Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy.

Nelson AC, Mould AW, Bikoff EK, Robertson EJ.

Nat Commun. 2018 Nov 19;9:16219. doi: 10.1038/ncomms16219.


Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.

Senft AD, Costello I, King HW, Mould AW, Bikoff EK, Robertson EJ.

Cell Rep. 2018 Aug 21;24(8):1977-1985.e7. doi: 10.1016/j.celrep.2018.07.077.


Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters.

Jansz N, Keniry A, Trussart M, Bildsoe H, Beck T, Tonks ID, Mould AW, Hickey P, Breslin K, Iminitoff M, Ritchie ME, McGlinn E, Kay GF, Murphy JM, Blewitt ME.

Nat Struct Mol Biol. 2018 Sep;25(9):766-777. doi: 10.1038/s41594-018-0111-z. Epub 2018 Aug 20.


Blimp-1/PRDM1 is a critical regulator of Type III Interferon responses in mammary epithelial cells.

Elias S, Robertson EJ, Bikoff EK, Mould AW.

Sci Rep. 2018 Jan 10;8(1):237. doi: 10.1038/s41598-017-18652-9.


Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation.

Nelson AC, Mould AW, Bikoff EK, Robertson EJ.

Sci Rep. 2017 Jul 28;7(1):6793. doi: 10.1038/s41598-017-06859-9.


Melanocyte transformation requires complete loss of all pocket protein function via a mechanism that mitigates the need for MAPK pathway activation.

Tonks ID, Mukhopadhyay P, Schroder WA, Sorolla A, Mould AW, Handoko HY, Ferguson B, Muller HK, Keith P, Hayward NK, Walker GJ, Kay GF.

Oncogene. 2017 Jun 29;36(26):3789-3795. doi: 10.1038/onc.2016.511. Epub 2017 Feb 13.


The transcriptional repressor Blimp1 is expressed in rare luminal progenitors and is essential for mammary gland development.

Ahmed MI, Elias S, Mould AW, Bikoff EK, Robertson EJ.

Development. 2016 May 15;143(10):1663-73. doi: 10.1242/dev.136358.


Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy.

Nelson AC, Mould AW, Bikoff EK, Robertson EJ.

Nat Commun. 2016 Apr 25;7:11414. doi: 10.1038/ncomms11414. Erratum in: Nat Commun. 2018 Nov 19;9:16219.


Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development.

Costello I, Nowotschin S, Sun X, Mould AW, Hadjantonakis AK, Bikoff EK, Robertson EJ.

Genes Dev. 2015 Oct 15;29(20):2108-22. doi: 10.1101/gad.268979.115.


Blimp1/Prdm1 Functions in Opposition to Irf1 to Maintain Neonatal Tolerance during Postnatal Intestinal Maturation.

Mould AW, Morgan MA, Nelson AC, Bikoff EK, Robertson EJ.

PLoS Genet. 2015 Jul 9;11(7):e1005375. doi: 10.1371/journal.pgen.1005375. eCollection 2015 Jul.


Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation.

Mould AW, Pang Z, Pakusch M, Tonks ID, Stark M, Carrie D, Mukhopadhyay P, Seidel A, Ellis JJ, Deakin J, Wakefield MJ, Krause L, Blewitt ME, Kay GF.

Epigenetics Chromatin. 2013 Jul 2;6(1):19. doi: 10.1186/1756-8935-6-19.


Alternative splicing regulates Prdm1/Blimp-1 DNA binding activities and corepressor interactions.

Morgan MA, Mould AW, Li L, Robertson EJ, Bikoff EK.

Mol Cell Biol. 2012 Sep;32(17):3403-13. doi: 10.1128/MCB.00174-12. Epub 2012 Jun 25.


Menin and p53 have non-synergistic effects on tumorigenesis in mice.

Loffler KA, Mould AW, Waring PM, Hayward NK, Kay GF.

BMC Cancer. 2012 Jun 18;12:252. doi: 10.1186/1471-2407-12-252.


Brca1 is involved in establishing murine pigmentation in a p53 and developmentally specific manner.

Tonks ID, Walker GJ, Mould AW, Ferguson B, Keith P, Hayward NK, Kay GF.

Pigment Cell Melanoma Res. 2012 Jul;25(4):530-2. doi: 10.1111/j.1755-148X.2012.01009.x. Epub 2012 Jun 1. No abstract available.


Alterations in gene expression in MEN1-associated insulinoma development.

Serewko-Auret MM, Mould AW, Loffler KA, Duncan R, Kay GF, Hayward NK.

Pancreas. 2010 Nov;39(8):1140-6. doi: 10.1097/MPA.0b013e3181dc67fc.


Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion.

Tonks ID, Mould AW, Schroder WA, Hacker E, Bosenberg M, Hayward NK, Walker GJ, Kay GF.

Pigment Cell Melanoma Res. 2010 Aug;23(4):564-70. doi: 10.1111/j.1755-148X.2010.00722.x. Epub 2010 May 26.


Dual loss of rb1 and Trp53 in the adrenal medulla leads to spontaneous pheochromocytoma.

Tonks ID, Mould AW, Schroder WA, Cotterill A, Hayward NK, Walker GJ, Kay GF.

Neoplasia. 2010 Mar;12(3):235-43.


Global expression profiling of sex cord stromal tumors from Men1 heterozygous mice identifies altered TGF-beta signaling, decreased Gata6 and increased Csf1r expression.

Mould AW, Duncan R, Serewko-Auret M, Loffler KA, Biondi C, Gartside M, Kay GF, Hayward NK.

Int J Cancer. 2009 Mar 1;124(5):1122-32. doi: 10.1002/ijc.24057.


Prophylactic but not therapeutic activity of a monoclonal antibody that neutralizes the binding of VEGF-B to VEGFR-1 in a murine collagen-induced arthritis model.

Mould AW, Scotney P, Greco SA, Hayward NK, Nash A, Kay GF.

Rheumatology (Oxford). 2008 Mar;47(3):263-6. doi: 10.1093/rheumatology/kem369. Epub 2008 Jan 19.


Global expression profiling of murine MEN1-associated tumors reveals a regulatory role for menin in transcription, cell cycle and chromatin remodelling.

Mould AW, Duncan R, Serewko-Auret M, Loffler KA, Biondi C, Gartside M, Kay GF, Hayward NK.

Int J Cancer. 2007 Aug 15;121(4):776-83.


Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice.

Loffler KA, Biondi CA, Gartside MG, Serewko-Auret MM, Duncan R, Tonks ID, Mould AW, Waring P, Muller HK, Kay GF, Hayward NK.

Oncogene. 2007 Jun 7;26(27):4009-17. Epub 2006 Dec 18.


Transgenic overexpression of vascular endothelial growth factor-B isoforms by endothelial cells potentiates postnatal vessel growth in vivo and in vitro.

Mould AW, Greco SA, Cahill MM, Tonks ID, Bellomo D, Patterson C, Zournazi A, Nash A, Scotney P, Hayward NK, Kay GF.

Circ Res. 2005 Sep 16;97(6):e60-70. Epub 2005 Aug 18. Erratum in: Circ Res. 2005 Sep 30;97(7):e72.


Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues.

Tonks ID, Nurcombe V, Paterson C, Zournazi A, Prather C, Mould AW, Kay GF.

Genesis. 2003 Nov;37(3):131-8.


Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis.

Mould AW, Tonks ID, Cahill MM, Pettit AR, Thomas R, Hayward NK, Kay GF.

Arthritis Rheum. 2003 Sep;48(9):2660-9.


Elemental signals regulating eosinophil accumulation in the lung.

Foster PS, Mould AW, Yang M, Mackenzie J, Mattes J, Hogan SP, Mahalingam S, Mckenzie AN, Rothenberg ME, Young IG, Matthaei KI, Webb DC.

Immunol Rev. 2001 Feb;179:173-81. Review.


Early pregnancy factor suppresses experimental autoimmune encephalomyelitis induced in Lewis rats with myelin basic protein and in SJL/J mice with myelin proteolipid protein peptide 139-151.

Zhang B, Harness J, Somodevilla-Torres MJ, Hillyard NC, Mould AW, Alewood D, Love SG, Alewood PF, Greer JM, Cavanagh AC, McCombe PA, Morton H.

J Neurol Sci. 2000 Dec 15;182(1):5-15.


The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity.

Mould AW, Ramsay AJ, Matthaei KI, Young IG, Rothenberg ME, Foster PS.

J Immunol. 2000 Feb 15;164(4):2142-50.


Cellular and molecular regulation of eosinophil trafficking to the lung.

Hogan SP, Mould AW, Young JM, Rothenberg ME, Ramsay AJ, Matthaei K, Young IG, Foster PS.

Immunol Cell Biol. 1998 Oct;76(5):454-60.


Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice.

Mould AW, Matthaei KI, Young IG, Foster PS.

J Clin Invest. 1997 Mar 1;99(5):1064-71.

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