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Items: 22


RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability.

Diring J, Mouilleron S, McDonald NQ, Treisman R.

Nat Cell Biol. 2019 Jul;21(7):845-855. doi: 10.1038/s41556-019-0337-y. Epub 2019 Jun 17.


Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.

Wirth M, Zhang W, Razi M, Nyoni L, Joshi D, O'Reilly N, Johansen T, Tooze SA, Mouilleron S.

Nat Commun. 2019 May 3;10(1):2055. doi: 10.1038/s41467-019-10059-6.


ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail.

Bertran MT, Mouilleron S, Zhou Y, Bajaj R, Uliana F, Kumar GS, van Drogen A, Lee R, Banerjee JJ, Hauri S, O'Reilly N, Gstaiger M, Page R, Peti W, Tapon N.

Nat Commun. 2019 Feb 15;10(1):771. doi: 10.1038/s41467-019-08686-0.


Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.

Birgisdottir ÅB, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, Zhang W, Lee R, O'Reilly N, Tooze SA, Lamark T, Johansen T.

Autophagy. 2019 Aug;15(8):1333-1355. doi: 10.1080/15548627.2019.1581009. Epub 2019 Mar 4.


A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase.

Kataria M, Mouilleron S, Seo MH, Corbi-Verge C, Kim PM, Uhlmann F.

Nat Struct Mol Biol. 2018 Dec;25(12):1093-1102. doi: 10.1038/s41594-018-0152-3. Epub 2018 Nov 19.


The Mechanism of Acetyl Transfer Catalyzed by Mycobacterium tuberculosis GlmU.

Craggs PD, Mouilleron S, Rejzek M, de Chiara C, Young RJ, Field RA, Argyrou A, de Carvalho LPS.

Biochemistry. 2018 Jun 19;57(24):3387-3401. doi: 10.1021/acs.biochem.8b00121. Epub 2018 May 2.


ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.

Skytte Rasmussen M, Mouilleron S, Kumar Shrestha B, Wirth M, Lee R, Bowitz Larsen K, Abudu Princely Y, O'Reilly N, Sjøttem E, Tooze SA, Lamark T, Johansen T.

Autophagy. 2017 May 4;13(5):834-853. doi: 10.1080/15548627.2017.1287651. Epub 2017 Feb 15.


RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.

Plaza-Menacho I, Barnouin K, Barry R, Borg A, Orme M, Chauhan R, Mouilleron S, Martínez-Torres RJ, Meier P, McDonald NQ.

Cell Rep. 2016 Dec 20;17(12):3319-3332. doi: 10.1016/j.celrep.2016.11.061.


Oncogenic RET kinase domain mutations perturb the autophosphorylation trajectory by enhancing substrate presentation in trans.

Plaza-Menacho I, Barnouin K, Goodman K, Martínez-Torres RJ, Borg A, Murray-Rust J, Mouilleron S, Knowles P, McDonald NQ.

Mol Cell. 2014 Mar 6;53(5):738-51. doi: 10.1016/j.molcel.2014.01.015. Epub 2014 Feb 20.


Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity.

Mouilleron S, Wiezlak M, O'Reilly N, Treisman R, McDonald NQ.

Structure. 2012 Nov 7;20(11):1960-70. doi: 10.1016/j.str.2012.08.031. Epub 2012 Oct 4.


G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly.

Wiezlak M, Diring J, Abella J, Mouilleron S, Way M, McDonald NQ, Treisman R.

J Cell Sci. 2012 Dec 1;125(Pt 23):5860-72. doi: 10.1242/jcs.112078. Epub 2012 Sep 12.


Structural basis for morpheein-type allosteric regulation of Escherichia coli glucosamine-6-phosphate synthase: equilibrium between inactive hexamer and active dimer.

Mouilleron S, Badet-Denisot MA, Pecqueur L, Madiona K, Assrir N, Badet B, Golinelli-Pimpaneau B.

J Biol Chem. 2012 Oct 5;287(41):34533-46. doi: 10.1074/jbc.M112.380378. Epub 2012 Jul 31.


Fluorescence-based incision assay for human XPF-ERCC1 activity identifies important elements of DNA junction recognition.

Bowles M, Lally J, Fadden AJ, Mouilleron S, Hammonds T, McDonald NQ.

Nucleic Acids Res. 2012 Jul;40(13):e101. doi: 10.1093/nar/gks284. Epub 2012 Mar 28.


Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator.

Mouilleron S, Langer CA, Guettler S, McDonald NQ, Treisman R.

Sci Signal. 2011 Jun 14;4(177):ra40. doi: 10.1126/scisignal.2001750.


Dynamics of glucosamine-6-phosphate synthase catalysis.

Mouilleron S, Badet-Denisot MA, Badet B, Golinelli-Pimpaneau B.

Arch Biochem Biophys. 2011 Jan 1;505(1):1-12. doi: 10.1016/ Epub 2010 Aug 13. Review.


Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL.

Mouilleron S, Guettler S, Langer CA, Treisman R, McDonald NQ.

EMBO J. 2008 Dec 3;27(23):3198-208. doi: 10.1038/emboj.2008.235. Epub 2008 Nov 13.


Ordering of C-terminal loop and glutaminase domains of glucosamine-6-phosphate synthase promotes sugar ring opening and formation of the ammonia channel.

Mouilleron S, Badet-Denisot MA, Golinelli-Pimpaneau B.

J Mol Biol. 2008 Apr 4;377(4):1174-85. doi: 10.1016/j.jmb.2008.01.077. Epub 2008 Feb 4.


Highlights of glucosamine-6P synthase catalysis.

Durand P, Golinelli-Pimpaneau B, Mouilleron S, Badet B, Badet-Denisot MA.

Arch Biochem Biophys. 2008 Jun 15;474(2):302-17. doi: 10.1016/ Epub 2008 Feb 6. Review.


Conformational changes in ammonia-channeling glutamine amidotransferases.

Mouilleron S, Golinelli-Pimpaneau B.

Curr Opin Struct Biol. 2007 Dec;17(6):653-64. Epub 2007 Oct 24. Review.


Ammonia channeling in bacterial glucosamine-6-phosphate synthase (Glms): molecular dynamics simulations and kinetic studies of protein mutants.

Floquet N, Mouilleron S, Daher R, Maigret B, Badet B, Badet-Denisot MA.

FEBS Lett. 2007 Jun 26;581(16):2981-7. Epub 2007 Jun 4.


Glutamine binding opens the ammonia channel and activates glucosamine-6P synthase.

Mouilleron S, Badet-Denisot MA, Golinelli-Pimpaneau B.

J Biol Chem. 2006 Feb 17;281(7):4404-12. Epub 2005 Dec 9.

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