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Items: 6

1.

Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: treprostinil is a potent DP1 and EP2 agonist.

Whittle BJ, Silverstein AM, Mottola DM, Clapp LH.

Biochem Pharmacol. 2012 Jul 1;84(1):68-75. doi: 10.1016/j.bcp.2012.03.012. Epub 2012 Mar 27.

2.

Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase.

Mottola DM, Kilts JD, Lewis MM, Connery HS, Walker QD, Jones SR, Booth RG, Hyslop DK, Piercey M, Wightman RM, Lawler CP, Nichols DE, Mailman RB.

J Pharmacol Exp Ther. 2002 Jun;301(3):1166-78.

PMID:
12023552
3.

Conformational analysis of D1 dopamine receptor agonists: pharmacophore assessment and receptor mapping.

Mottola DM, Laiter S, Watts VJ, Tropsha A, Wyrick SD, Nichols DE, Mailman RB.

J Med Chem. 1996 Jan 5;39(1):285-96.

PMID:
8568818
4.

Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist.

Mottola DM, Brewster WK, Cook LL, Nichols DE, Mailman RB.

J Pharmacol Exp Ther. 1992 Jul;262(1):383-93.

PMID:
1352553
5.

trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist.

Brewster WK, Nichols DE, Riggs RM, Mottola DM, Lovenberg TW, Lewis MH, Mailman RB.

J Med Chem. 1990 Jun;33(6):1756-64.

PMID:
1971308
6.

Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist.

Lovenberg TW, Brewster WK, Mottola DM, Lee RC, Riggs RM, Nichols DE, Lewis MH, Mailman RB.

Eur J Pharmacol. 1989 Jul 4;166(1):111-3. No abstract available.

PMID:
2572425

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