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Items: 1 to 20 of 28

1.

Adipocyte lipolysis: from molecular mechanisms of regulation to disease and therapeutics.

Yang A, Mottillo EP.

Biochem J. 2020 Mar 13;477(5):985-1008. doi: 10.1042/BCJ20190468.

PMID:
32168372
2.

Genetically-encoded sensors to detect fatty acid production and trafficking.

Mottillo EP, Zhang H, Yang A, Zhou L, Granneman JG.

Mol Metab. 2019 Nov;29:55-64. doi: 10.1016/j.molmet.2019.08.012. Epub 2019 Aug 20.

3.

Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes.

Yang A, Mottillo EP, Mladenovic-Lucas L, Zhou L, Granneman JG.

Nat Metab. 2019 May;1(5):560-569. doi: 10.1038/s42255-019-0066-3. Epub 2019 May 6.

4.

SERCA2b Cycles Its Way to UCP1-Independent Thermogenesis in Beige Fat.

Mottillo EP, Ramseyer VD, Granneman JG.

Cell Metab. 2018 Jan 9;27(1):7-9. doi: 10.1016/j.cmet.2017.12.015.

5.

FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis.

Mottillo EP, Desjardins EM, Fritzen AM, Zou VZ, Crane JD, Yabut JM, Kiens B, Erion DM, Lanba A, Granneman JG, Talukdar S, Steinberg GR.

Mol Metab. 2017 Apr 5;6(6):471-481. doi: 10.1016/j.molmet.2017.04.001. eCollection 2017 Jun.

6.

Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1.

Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR.

Diabetes. 2016 Nov;65(11):3352-3361. Epub 2016 Aug 23.

7.

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function.

Mottillo EP, Desjardins EM, Crane JD, Smith BK, Green AE, Ducommun S, Henriksen TI, Rebalka IA, Razi A, Sakamoto K, Scheele C, Kemp BE, Hawke TJ, Ortega J, Granneman JG, Steinberg GR.

Cell Metab. 2016 Jul 12;24(1):118-29. doi: 10.1016/j.cmet.2016.06.006.

8.

Characterization of Eicosanoids Produced by Adipocyte Lipolysis: IMPLICATION OF CYCLOOXYGENASE-2 IN ADIPOSE INFLAMMATION.

Gartung A, Zhao J, Chen S, Mottillo E, VanHecke GC, Ahn YH, Maddipati KR, Sorokin A, Granneman J, Lee MJ.

J Biol Chem. 2016 Jul 29;291(31):16001-10. doi: 10.1074/jbc.M116.725937. Epub 2016 May 31.

9.

Adipose Tissue Remodeling During Endurance Training.

Mottillo EP.

Exerc Sport Sci Rev. 2016 Jan;44(1):3. doi: 10.1249/JES.0000000000000072. No abstract available.

PMID:
26674095
10.

Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle.

Sanders MA, Madoux F, Mladenovic L, Zhang H, Ye X, Angrish M, Mottillo EP, Caruso JA, Halvorsen G, Roush WR, Chase P, Hodder P, Granneman JG.

Cell Metab. 2015 Nov 3;22(5):851-60. doi: 10.1016/j.cmet.2015.08.023. Epub 2015 Sep 24.

11.

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis.

Crane JD, Palanivel R, Mottillo EP, Bujak AL, Wang H, Ford RJ, Collins A, Blümer RM, Fullerton MD, Yabut JM, Kim JJ, Ghia JE, Hamza SM, Morrison KM, Schertzer JD, Dyck JR, Khan WI, Steinberg GR.

Nat Med. 2015 Feb;21(2):166-72. doi: 10.1038/nm.3766. Epub 2014 Dec 8.

12.

Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity.

Zhang W, Mottillo EP, Zhao J, Gartung A, VanHecke GC, Lee JF, Maddipati KR, Xu H, Ahn YH, Proia RL, Granneman JG, Lee MJ.

J Biol Chem. 2014 Nov 14;289(46):32178-85. doi: 10.1074/jbc.M114.601096. Epub 2014 Sep 24.

13.

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation.

Mottillo EP, Balasubramanian P, Lee YH, Weng C, Kershaw EE, Granneman JG.

J Lipid Res. 2014 Nov;55(11):2276-86. doi: 10.1194/jlr.M050005. Epub 2014 Sep 5.

14.

Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation.

Contreras GA, Lee YH, Mottillo EP, Granneman JG.

Am J Physiol Endocrinol Metab. 2014 Nov 1;307(9):E793-9. doi: 10.1152/ajpendo.00033.2014. Epub 2014 Sep 2.

15.

A standardized infrared imaging technique that specifically detects UCP1-mediated thermogenesis in vivo.

Crane JD, Mottillo EP, Farncombe TH, Morrison KM, Steinberg GR.

Mol Metab. 2014 Apr 21;3(4):490-4. doi: 10.1016/j.molmet.2014.04.007. eCollection 2014 Jul.

16.

Use of fluorescence microscopy to probe intracellular lipolysis.

Mottillo EP, Paul GM, Moore HP, Granneman JG.

Methods Enzymol. 2014;538:263-78. doi: 10.1016/B978-0-12-800280-3.00015-3.

17.

Adipose tissue plasticity from WAT to BAT and in between.

Lee YH, Mottillo EP, Granneman JG.

Biochim Biophys Acta. 2014 Mar;1842(3):358-69. doi: 10.1016/j.bbadis.2013.05.011. Epub 2013 May 17. Review.

18.

Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply.

Mottillo EP, Bloch AE, Leff T, Granneman JG.

J Biol Chem. 2012 Jul 20;287(30):25038-48. doi: 10.1074/jbc.M112.374041. Epub 2012 Jun 8.

19.

In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding.

Lee YH, Petkova AP, Mottillo EP, Granneman JG.

Cell Metab. 2012 Apr 4;15(4):480-91. doi: 10.1016/j.cmet.2012.03.009.

20.

Intracellular fatty acids suppress β-adrenergic induction of PKA-targeted gene expression in white adipocytes.

Mottillo EP, Granneman JG.

Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E122-31. doi: 10.1152/ajpendo.00039.2011. Epub 2011 Apr 19.

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