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Blood anti-Müllerian hormone is a possible determinant of recurrent early miscarriage, yet not conclusive in predicting a further miscarriage.

Leclercq E, de Saint Martin L, Bohec C, Le Martelot MT, Roche S, Alavi Z, Mottier D, Pasquier E.

Reprod Biomed Online. 2019 Apr 12. pii: S1472-6483(19)30380-3. doi: 10.1016/j.rbmo.2019.04.004. [Epub ahead of print]


Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism: A Prospective Cohort Study.

Le Moigne E, Timsit S, Ben Salem D, Didier R, Jobic Y, Paleiron N, Le Mao R, Joseph T, Hoffmann C, Dion A, Rousset J, Le Gal G, Lacut K, Leroyer C, Mottier D, Couturaud F.

Ann Intern Med. 2019 May 7. doi: 10.7326/M18-3485. [Epub ahead of print]


Hydroxychloroquine for prevention of recurrent miscarriage: study protocol for a multicentre randomised placebo-controlled trial BBQ study.

Pasquier E, de Saint-Martin L, Marhic G, Chauleur C, Bohec C, Bretelle F, Lejeune-Saada V, Hannigsberg J, Plu-Bureau G, Cogulet V, Merviel P, Mottier D.

BMJ Open. 2019 Mar 20;9(3):e025649. doi: 10.1136/bmjopen-2018-025649.


A randomized, double-blind, placebo-controlled trial on the efficacy of tranexamic acid combined with rivaroxaban thromboprophylaxis in reducing blood loss after primary cementless total hip arthroplasty.

Clavé A, Gérard R, Lacroix J, Baynat C, Danguy des Déserts M, Gatineau F, Mottier D.

Bone Joint J. 2019 Feb;101-B(2):207-212. doi: 10.1302/0301-620X.101B2.BJJ-2018-0898.R1.


Six months versus two years of oral anticoagulation after a first episode of unprovoked deep-vein thrombosis. The PADIS-DVT randomized clinical trial.

Couturaud F, Pernod G, Presles E, Duhamel E, Jego P, Provost K, Pan-Petesch B, Sollier CBD, Tromeur C, Hoffmann C, Bressollette L, Lorillon P, Girard P, Le Moigne E, Le Hir A, Guégan M, Laporte S, Mismetti P, Lacut K, Bosson JL, Bertoletti L, Sanchez O, Meyer G, Leroyer C, Mottier D; “PADIS-DVT” investigators.

Haematologica. 2019 Jul;104(7):1493-1501. doi: 10.3324/haematol.2018.210971. Epub 2019 Jan 3.


Incidence of upper-extremity deep vein thrombosis in western France: a community-based study.

Delluc A, Le Mao R, Tromeur C, Chambry N, Rault-Nagel H, Bressollette L, Mottier D, Couturaud F, Lacut K.

Haematologica. 2019 Jan;104(1):e29-e31. doi: 10.3324/haematol.2018.194951. Epub 2018 Aug 3. No abstract available.


Real-world incidence of cancer following a first unprovoked venous thrombosis: Results from the EPIGETBO study.

Delluc A, Ianotto JC, Tromeur C, De Moreuil C, Couturaud F, Lacut K, Le Moigne E, Louis P, Thereaux J, Metges JP, Mottier D.

Thromb Res. 2018 Apr;164:79-84. doi: 10.1016/j.thromres.2018.02.151. Epub 2018 Mar 2.


Risk factors for recurrent venous thromboembolism after unprovoked pulmonary embolism: the PADIS-PE randomised trial.

Tromeur C, Sanchez O, Presles E, Pernod G, Bertoletti L, Jego P, Duhamel E, Provost K, Parent F, Robin P, Deloire L, Leven F, Mingant F, Bressollette L, Le Roux PY, Salaun PY, Nonent M, Pan-Petesch B, Planquette B, Girard P, Lacut K, Melac S, Mismetti P, Laporte S, Meyer G, Mottier D, Leroyer C, Couturaud F; PADIS-PE Investigators18.

Eur Respir J. 2018 Jan 4;51(1). pii: 1701202. doi: 10.1183/13993003.01202-2017. Print 2018 Jan.


Incidence and impact of atrial arrhythmias on thrombotic events in MPNs.

Mahé K, Delluc A, Chauveau A, Castellant P, Mottier D, Dalbies F, Berthou C, Guillerm G, Lippert E, Ianotto JC.

Ann Hematol. 2018 Jan;97(1):101-107. doi: 10.1007/s00277-017-3164-x. Epub 2017 Nov 21.


Risk of recurrent venous thromboembolism in COPD patients: results from a prospective cohort study.

Le Mao R, Tromeur C, Bazire A, Gouillou M, Guegan M, Lacut K, Delluc A, Mottier D, Leroyer C, Couturaud F.

Eur Respir J. 2017 Jul 27;50(1). pii: 1700094. doi: 10.1183/13993003.00094-2017. Print 2017 Jul.


Association between hospitalization for acute medical illness and VTE risk: A lower efficacy of thromboprophylaxis in elderly patients? Results from the EDITH case-control study.

Hemon F, Fouchard F, Tromeur C, Lacut K, Le Gal G, Mottier D, Couturaud F, Delluc A.

Eur J Intern Med. 2017 Oct;44:39-43. doi: 10.1016/j.ejim.2017.05.029. Epub 2017 Jun 22.


Administration of direct oral anticoagulants in patients with myeloproliferative neoplasms.

Ianotto JC, Couturier MA, Galinat H, Mottier D, Berthou C, Guillerm G, Lippert E, Delluc A.

Int J Hematol. 2017 Oct;106(4):517-521. doi: 10.1007/s12185-017-2282-5. Epub 2017 Jun 16.


[Abdominal pain as a presentation by lead poisoning. Case report].

Mottier DM, Cargnel E.

Arch Argent Pediatr. 2017 Apr 1;115(2):e96-e98. doi: 10.5546/aap.2017.e96. Spanish.


Long-term mortality in older patients discharged after acute decompensated heart failure: a prospective cohort study.

Natella PA, Le Corvoisier P, Paillaud E, Renaud B, Mahé I, Bergmann JF, Perchet H, Mottier D, Montagne O, Bastuji-Garin S.

BMC Geriatr. 2017 Jan 26;17(1):34. doi: 10.1186/s12877-017-0419-2.


Current incidence of venous thromboembolism and comparison with 1998: a community-based study in Western France.

Delluc A, Tromeur C, Le Ven F, Gouillou M, Paleiron N, Bressollette L, Nonent M, Salaun PY, Lacut K, Leroyer C, Le Gal G, Couturaud F, Mottier D; EPIGETBO study group.

Thromb Haemost. 2016 Oct 28;116(5):967-974. Epub 2016 Jul 28.


JAK2V617F and calreticulin mutations in recurrent venous thromboembolism: results from the EDITH prospective cohort.

Ianotto JC, Chauveau A, Mottier D, Ugo V, Berthou C, Lippert E, Delluc A.

Ann Hematol. 2017 Mar;96(3):383-386. doi: 10.1007/s00277-016-2853-1. Epub 2016 Oct 20.


Multifaceted Intervention to Prevent Venous Thromboembolism in Patients Hospitalized for Acute Medical Illness: A Multicenter Cluster-Randomized Trial.

Roy PM, Rachas A, Meyer G, Le Gal G, Durieux P, El Kouri D, Honnart D, Schmidt J, Legall C, Hausfater P, Chrétien JM, Mottier D; PREVENU study group.

PLoS One. 2016 May 26;11(5):e0154832. doi: 10.1371/journal.pone.0154832. eCollection 2016.


Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.

Meijer L, Nelson DJ, Riazanski V, Gabdoulkhakova AG, Hery-Arnaud G, Le Berre R, Loaëc N, Oumata N, Galons H, Nowak E, Gueganton L, Dorothée G, Prochazkova M, Hall B, Kulkarni AB, Gray RD, Rossi AG, Witko-Sarsat V, Norez C, Becq F, Ravel D, Mottier D, Rault G.

J Innate Immun. 2016;8(4):330-49. doi: 10.1159/000444256. Epub 2016 Mar 18. Review.


Thrombophilia and the Risk of Recurrent Venous Thromboembolism--Reply.

Couturaud F, Meyer G, Mottier D.

JAMA. 2015 Nov 10;314(18):1976. doi: 10.1001/jama.2015.12610. No abstract available.


Risk of recurrent venous thromboembolism on progestin-only contraception: a cohort study.

Le Moigne E, Tromeur C, Delluc A, Gouillou M, Alavi Z, Lacut K, Mottier D, Le Gal G.

Haematologica. 2016 Jan;101(1):e12-4. doi: 10.3324/haematol.2015.134882. Epub 2015 Oct 9. No abstract available.


Absence of CALR mutation among a cohort of 394 unselected patients with a first episode of unprovoked venous thromboembolism.

Ianotto JC, Chauveau A, Luque Paz D, Delluc A, Tromeur C, Couturier MA, Gouillou M, Berthou C, Mottier D, Ugo V.

Thromb Haemost. 2016 Jan;115(1):225-6. doi: 10.1160/TH15-02-0134. Epub 2015 Aug 20. No abstract available.


Six Months vs Extended Oral Anticoagulation After a First Episode of Pulmonary Embolism: The PADIS-PE Randomized Clinical Trial.

Couturaud F, Sanchez O, Pernod G, Mismetti P, Jego P, Duhamel E, Provost K, dit Sollier CB, Presles E, Castellant P, Parent F, Salaun PY, Bressollette L, Nonent M, Lorillon P, Girard P, Lacut K, Guégan M, Bosson JL, Laporte S, Leroyer C, Décousus H, Meyer G, Mottier D; PADIS-PE Investigators.

JAMA. 2015 Jul 7;314(1):31-40. doi: 10.1001/jama.2015.7046.


Enoxaparin for prevention of unexplained recurrent miscarriage: a multicenter randomized double-blind placebo-controlled trial.

Pasquier E, de Saint Martin L, Bohec C, Chauleur C, Bretelle F, Marhic G, Le Gal G, Debarge V, Lecomte F, Denoual-Ziad C, Lejeune-Saada V, Douvier S, Heisert M, Mottier D.

Blood. 2015 Apr 2;125(14):2200-5. doi: 10.1182/blood-2014-11-610857. Epub 2015 Jan 30.


Functional status and co-morbidities are associated with in-hospital mortality among older patients with acute decompensated heart failure: a multicentre prospective cohort study.

Le Corvoisier P, Bastuji-Garin S, Renaud B, Mahé I, Bergmann JF, Perchet H, Paillaud E, Mottier D, Montagne O.

Age Ageing. 2015 Mar;44(2):225-31. doi: 10.1093/ageing/afu144. Epub 2014 Oct 12.


Factors that predict thrombosis in relatives of patients with venous thromboembolism.

Couturaud F, Leroyer C, Tromeur C, Julian JA, Kahn SR, Ginsberg JS, Wells PS, Douketis JD, Mottier D, Kearon C.

Blood. 2014 Sep 25;124(13):2124-30. doi: 10.1182/blood-2014-03-559757. Epub 2014 Jul 21.


Prevalence of antiphospholipid antibodies in psychiatric patients users and non-users of antipsychotics.

Delluc A, Rousseau A, Le Galudec M, Canceil O, Woodhams B, Etienne S, Walter M, Mottier D, Van Dreden P, Lacut K.

Br J Haematol. 2014 Jan;164(2):272-9. doi: 10.1111/bjh.12627. Epub 2013 Nov 5.


Venous thromboembolism prophylaxis in patients undergoing abdominal or pelvic surgery for cancer--a real-world, prospective, observational French study: PRéOBS.

Samama CM, Boubli L, Coloby P, Debourdeau P, Gruel Y, Mariette C, Mottier D, Rischmann P, Toubiana L, Steib A.

Thromb Res. 2014 Jun;133(6):985-92. doi: 10.1016/j.thromres.2013.10.038. Epub 2013 Nov 1.


Unexplained pregnancy loss: a marker of basal endothelial dysfunction?

Pasquier E, De Saint Martin L, Bohec C, Collet M, Dignat George F, Mottier D.

Fertil Steril. 2013 Oct;100(4):1013-7. doi: 10.1016/j.fertnstert.2013.06.008. Epub 2013 Jul 2.


Body mass index, a major confounder to insulin resistance association with unprovoked venous thromboembolism. Results from the EDITH case-control study.

Delluc A, De Moreuil C, Kerspern H, Le Moigne E, Mottier D, Tromeur C, Carre JL, Le Gal G, Lacut K.

Thromb Haemost. 2013 Sep;110(3):593-7. doi: 10.1160/TH13-01-0048. Epub 2013 Jun 27.


Risk of recurrent venous thromboembolism among young women after a first event while exposed to combined oral contraception versus not exposed to: a cohort study.

Le Moigne E, Delluc A, Tromeur C, Nowak E, Mottier D, Lacut K, Le Gal G.

Thromb Res. 2013 Jul;132(1):51-5. doi: 10.1016/j.thromres.2013.05.028. Epub 2013 Jun 18.


[Evaluation of preoperative non-invasive ventilation in thoracic surgery for lung cancer: the preOVNI study GFPC 12-01].

Paleiron N, André M, Grassin F, Chouaïd C, Venissac N, Margery J, Couturaud F, Noël-Savina E, Tromeur C, Vinsonneau U, Vedrine L, Leroyer C, Nowak E, Berard H, Thomas P, Brouchet L, Bagan P, Fournel P, Mottier D, Robinet G.

Rev Mal Respir. 2013 Mar;30(3):231-7. doi: 10.1016/j.rmr.2012.10.601. Epub 2012 Dec 13. French.


[Aspirin for secondary prevention of venous thromboembolism. WARFASA: far from being conclusive].

Delluc A, Lacut K, Mottier D.

Rev Med Interne. 2013 Feb;34(2):69-72. doi: 10.1016/j.revmed.2012.10.363. Epub 2012 Nov 13. Review. French. No abstract available.


Incidence of venous thromboembolism in psychiatric units.

Delluc A, Montavon S, Canceil O, Carpentier M, Nowak E, Mercier B, Bressollette L, Etienne S, Walter M, Mottier D, Lacut K.

Thromb Res. 2012 Dec;130(6):e283-8. doi: 10.1016/j.thromres.2012.10.002. Epub 2012 Oct 23.


Lipid lowering drugs and the risk of recurrent venous thromboembolism.

Delluc A, Tromeur C, Le Moigne E, Nowak E, Mottier D, Le Gal G, Lacut K.

Thromb Res. 2012 Dec;130(6):859-63. doi: 10.1016/j.thromres.2012.08.296. Epub 2012 Aug 30.


New anticoagulants in the treatment of VTE.

Le Gal G, Mottier D.

Semin Respir Crit Care Med. 2012 Apr;33(2):191-8. doi: 10.1055/s-0032-1311799. Epub 2012 May 30. Review.


Diagnostic value of single complete compression ultrasonography in pregnant and postpartum women with suspected deep vein thrombosis: prospective study.

Le Gal G, Kercret G, Ben Yahmed K, Bressollette L, Robert-Ebadi H, Riberdy L, Louis P, Delluc A, Labalette ML, Baba-Ahmed M, Bounameaux H, Mottier D, Righini M; EDVIGE Study Group.

BMJ. 2012 Apr 24;344:e2635. doi: 10.1136/bmj.e2635.


[Epidemiology and risk factors of venous thromboembolism].

Delluc A, Le Ven F, Mottier D, Le Gal G.

Rev Mal Respir. 2012 Feb;29(2):254-66. doi: 10.1016/j.rmr.2011.12.001. Epub 2012 Jan 4. Review. French.


Lipid parameters, lipid lowering drugs and the risk of venous thromboembolism.

Delluc A, Malécot JM, Kerspern H, Nowak E, Carre JL, Mottier D, Le Gal G, Lacut K.

Atherosclerosis. 2012 Jan;220(1):184-8. doi: 10.1016/j.atherosclerosis.2011.10.007. Epub 2011 Oct 14.


Impact of genetic factors (VKORC1, CYP2C9, CYP4F2 and EPHX1) on the anticoagulation response to fluindione.

Lacut K, Ayme-Dietrich E, Gourhant L, Poulhazan E, Andro M, Becquemont L, Mottier D, Le Gal G, Verstuyft C.

Br J Clin Pharmacol. 2012 Mar;73(3):428-36. doi: 10.1111/j.1365-2125.2011.04095.x.


Site of venous thromboembolism and prothrombotic mutations according to body mass index. Results from the EDITH study.

Delluc A, Le Moigne E, Tromeur C, Noel-Savina E, Couturaud F, Mottier D, Le Gal G, Lacut K.

Br J Haematol. 2011 Aug;154(4):486-91. doi: 10.1111/j.1365-2141.2011.08592.x. Epub 2011 Jun 14.


Safety profile of tinzaparin versus subcutaneous unfractionated heparin in elderly patients with impaired renal function treated for acute deep vein thrombosis: the Innohep® in Renal Insufficiency Study (IRIS).

Leizorovicz A, Siguret V, Mottier D; Innohep® in Renal Insufficiency Study Steering Committee, Leizorovicz A, Siguret V, Mottier D, Clonier F, Janas M, Stinson J, Townshend G, Maddalena M.

Thromb Res. 2011 Jul;128(1):27-34. doi: 10.1016/j.thromres.2011.03.002. Epub 2011 Apr 7.


Venous thromboembolism in patients with pancreatic cancer: implications of circulating tissue factor.

Delluc A, Rousseau A, Delluc C, Le Moigne E, Le Gal G, Mottier D, Van Dreden P, Lacut K.

Blood Coagul Fibrinolysis. 2011 Jun;22(4):295-300. doi: 10.1097/MBC.0b013e32834512f4.


Increased thrombin generation measured in the presence of thrombomodulin in women with early pregnancy loss.

de Saint Martin L, Duchemin J, Bohec C, Couturaud F, Mottier D, Collet M, Blouch MT, Pasquier E.

Fertil Steril. 2011 Apr;95(5):1813-5.e1. doi: 10.1016/j.fertnstert.2010.11.019. Epub 2010 Dec 3.


[Incidence, risk factors and skin manifestations of post-thrombotic syndrome: a four-year follow-up of patients included in the EDITH study].

Delluc A, Gouedard C, De Saint Martin L, Garcia C, Roguedas AM, Bressollette L, Misery L, Mottier D, Le Gal G.

Rev Med Interne. 2010 Nov;31(11):729-34. doi: 10.1016/j.revmed.2010.07.018. Epub 2010 Sep 29. French.


Association of common genetic variations and idiopathic venous thromboembolism. Results from EDITh, a hospital-based case-control study.

Delluc A, Gourhant L, Lacut K, Mercier B, Audrezet MP, Nowak E, Oger E, Leroyer C, Mottier D, Le Gal G, Couturaud F.

Thromb Haemost. 2010 Jun;103(6):1161-9. doi: 10.1160/TH09-07-0430. Epub 2010 Mar 29.


Antihypertensive drugs and risk of venous thromboembolism: results from the EDITH case-control study.

Belattar FZ, Delluc A, Le Gal G, Leroyer C, Mottier D, Oger E, Lacut K.

Fundam Clin Pharmacol. 2010 Apr;24(2):255-9. doi: 10.1111/j.1472-8206.2009.00752.x. Epub 2009 Aug 17.


Factors that predict risk of thrombosis in relatives of patients with unprovoked venous thromboembolism.

Couturaud F, Leroyer C, Julian JA, Kahn SR, Ginsberg JS, Wells PS, Douketis JD, Mottier D, Kearon C.

Chest. 2009 Dec;136(6):1537-1545. doi: 10.1378/chest.09-0757. Epub 2009 Jul 10.


Underweight is associated with a reduced risk of venous thromboembolism. Results from the EDITH case-control study.

Delluc A, Mottier D, Le Gal G, Oger E, Lacut K.

J Thromb Haemost. 2009 Apr;7(4):728-9. doi: 10.1111/j.1538-7836.2009.03280.x. Epub 2009 Jan 13. No abstract available.


[Drugs and venous thromboembolism].

Lacut K, Mottier D, Pottier P.

Rev Pneumol Clin. 2008 Dec;64(6):290-7. doi: 10.1016/j.pneumo.2008.09.005. Epub 2008 Nov 17. Review. French.


[Clinical prediction rule for diagnosing deep vein thrombosis in primary care].

Gagne P, Simon L, Le Pape F, Bressollette L, Mottier D, Le Gal G; pour le groupe Géné-GETBO.

Presse Med. 2009 Apr;38(4):525-33. doi: 10.1016/j.lpm.2008.09.022. Epub 2008 Dec 4. French.


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