Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 125

1.

Oxytocin/vasopressin-like peptide inotocin regulates cuticular hydrocarbon synthesis and water balancing in ants.

Koto A, Motoyama N, Tahara H, McGregor S, Moriyama M, Okabe T, Miura M, Keller L.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5597-5606. doi: 10.1073/pnas.1817788116. Epub 2019 Mar 6.

2.

Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure.

Tanoue Y, Toyoda T, Sun J, Mustofa MK, Tateishi C, Endo S, Motoyama N, Araki K, Wu D, Okuno Y, Tsukamoto T, Takeya M, Ihn H, Vaziri C, Tateishi S.

J Invest Dermatol. 2018 Dec;138(12):2550-2557. doi: 10.1016/j.jid.2018.05.015. Epub 2018 May 31.

PMID:
29859927
3.

CHK2 is involved in the p53-independent radiosensitizing effects of valproic acid.

Choo DW, Goh SH, Cho YW, Baek HJ, Park EJ, Motoyama N, Kim TH, Kim JY, Kim SS.

Oncol Lett. 2017 Apr;13(4):2591-2598. doi: 10.3892/ol.2017.5792. Epub 2017 Mar 1.

4.

Down-regulation of zinc transporter-1 in astrocytes induces neuropathic pain via the brain-derived neurotrophic factor - K+-Cl- co-transporter-2 signaling pathway in the mouse spinal cord.

Kitayama T, Morita K, Motoyama N, Dohi T.

Neurochem Int. 2016 Dec;101:120-131. doi: 10.1016/j.neuint.2016.11.001. Epub 2016 Nov 3.

PMID:
27818163
5.

Autophosphorylation of Specific Threonine and Tyrosine Residues in Arabidopsis CERK1 is Essential for the Activation of Chitin-Induced Immune Signaling.

Suzuki M, Shibuya M, Shimada H, Motoyama N, Nakashima M, Takahashi S, Suto K, Yoshida I, Matsui S, Tsujimoto N, Ohnishi M, Ishibashi Y, Fujimoto Z, Desaki Y, Kaku H, Kito K, Shibuya N.

Plant Cell Physiol. 2016 Nov;57(11):2312-2322. Epub 2016 Aug 26.

PMID:
27565204
6.

Targeting of Chk2 as a countermeasure to dose-limiting toxicity triggered by topoisomerase-II (TOP2) poisons.

Gokare P, Navaraj A, Zhang S, Motoyama N, Sung SS, Finnberg NK.

Oncotarget. 2016 May 17;7(20):29520-30. doi: 10.18632/oncotarget.8790.

7.

Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors.

Barabino A, Plamondon V, Abdouh M, Chatoo W, Flamier A, Hanna R, Zhou S, Motoyama N, Hébert M, Lavoie J, Bernier G.

Development. 2016 May 1;143(9):1571-84. doi: 10.1242/dev.125351. Epub 2016 Mar 10.

8.

FoxO3 suppresses Myc-driven lymphomagenesis.

Vandenberg CJ, Motoyama N, Cory S.

Cell Death Dis. 2016 Jan 14;6:e2046. doi: 10.1038/cddis.2015.396.

9.

Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity.

Finnberg NK, Gokare P, Navaraj A, Lang Kuhs KA, Cerniglia G, Yagita H, Takeda K, Motoyama N, El-Deiry WS.

Cancer Res. 2016 Feb 1;76(3):700-12. doi: 10.1158/0008-5472.CAN-15-2759. Epub 2015 Nov 25.

10.

[Pain relieving effect of platelet-activating factor (PAF) antagonists in a bone cancer pain model].

Morita K, Motoyama N, Kitayama T, Shiraishi S, Dohi T.

Nihon Yakurigaku Zasshi. 2015 Aug;146(2):87-92. doi: 10.1254/fpj.146.87. Japanese. No abstract available.

PMID:
26256746
11.

SIRT1 suppresses the senescence-associated secretory phenotype through epigenetic gene regulation.

Hayakawa T, Iwai M, Aoki S, Takimoto K, Maruyama M, Maruyama W, Motoyama N.

PLoS One. 2015 Jan 30;10(1):e0116480. doi: 10.1371/journal.pone.0116480. eCollection 2015.

12.

Profiling contents of water-soluble metabolites and mineral nutrients to evaluate the effects of pesticides and organic and chemical fertilizers on tomato fruit quality.

Watanabe M, Ohta Y, Licang S, Motoyama N, Kikuchi J.

Food Chem. 2015 Feb 15;169:387-95. doi: 10.1016/j.foodchem.2014.07.155. Epub 2014 Aug 10.

PMID:
25236242
13.

Relief of cancer pain by glycine transporter inhibitors.

Motoyama N, Morita K, Shiraishi S, Kitayama T, Kanematsu T, Uezono Y, Dohi T.

Anesth Analg. 2014 Oct;119(4):988-95. doi: 10.1213/ANE.0000000000000388.

PMID:
25076101
14.

Necessary and sufficient role for a mitosis skip in senescence induction.

Johmura Y, Shimada M, Misaki T, Naiki-Ito A, Miyoshi H, Motoyama N, Ohtani N, Hara E, Nakamura M, Morita A, Takahashi S, Nakanishi M.

Mol Cell. 2014 Jul 3;55(1):73-84. doi: 10.1016/j.molcel.2014.05.003. Epub 2014 Jun 5.

15.

Palliation of bone cancer pain by antagonists of platelet-activating factor receptors.

Morita K, Shiraishi S, Motoyama N, Kitayama T, Kanematsu T, Uezono Y, Dohi T.

PLoS One. 2014 Mar 17;9(3):e91746. doi: 10.1371/journal.pone.0091746. eCollection 2014.

16.

The use of granulocyte-colony stimulating factor induced mobilization for isolation of dental pulp stem cells with high regenerative potential.

Murakami M, Horibe H, Iohara K, Hayashi Y, Osako Y, Takei Y, Nakata K, Motoyama N, Kurita K, Nakashima M.

Biomaterials. 2013 Dec;34(36):9036-47. doi: 10.1016/j.biomaterials.2013.08.011. Epub 2013 Aug 27. Erratum in: Biomaterials. 2016 May;89: 166-7.

17.

Presence of LYM2 dependent but CERK1 independent disease resistance in Arabidopsis.

Narusaka Y, Shinya T, Narusaka M, Motoyama N, Shimada H, Murakami K, Shibuya N.

Plant Signal Behav. 2013 Sep;8(9). pii: e25345. doi: 10.4161/psb.25345. Epub 2013 Aug 2.

18.

Pain-releasing action of platelet-activating factor (PAF) antagonists in neuropathic pain animal models and the mechanisms of action.

Motoyama N, Morita K, Kitayama T, Shiraishi S, Uezono Y, Nishimura F, Kanematsu T, Dohi T.

Eur J Pain. 2013 Sep;17(8):1156-67. doi: 10.1002/j.1532-2149.2013.00289.x. Epub 2013 Jan 27.

PMID:
23355413
19.

Functional characterization of CEBiP and CERK1 homologs in arabidopsis and rice reveals the presence of different chitin receptor systems in plants.

Shinya T, Motoyama N, Ikeda A, Wada M, Kamiya K, Hayafune M, Kaku H, Shibuya N.

Plant Cell Physiol. 2012 Oct;53(10):1696-706. doi: 10.1093/pcp/pcs113. Epub 2012 Aug 13.

PMID:
22891159
20.

Effect of sesame leaf diet on detoxification activities of insects with different feeding behavior.

Sintim HO, Tashiro T, Motoyama N.

Arch Insect Biochem Physiol. 2012 Nov;81(3):148-59. doi: 10.1002/arch.21045. Epub 2012 Aug 10.

PMID:
22886908
21.

Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis.

Demidov ON, Zhu Y, Kek C, Goloudina AR, Motoyama N, Bulavin DV.

Cell Death Differ. 2012 Nov;19(11):1761-8. doi: 10.1038/cdd.2012.57. Epub 2012 May 4.

22.

Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.

Lee IH, Kawai Y, Fergusson MM, Rovira II, Bishop AJ, Motoyama N, Cao L, Finkel T.

Science. 2012 Apr 13;336(6078):225-8. doi: 10.1126/science.1218395. Erratum in: Science. 2012 Aug 24;337(6097):911. Science. 2013 Aug 2;341(6145):457.

23.

Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo.

Shinohara K, Kawasumi A, Takamatsu A, Yoshiba S, Botilde Y, Motoyama N, Reith W, Durand B, Shiratori H, Hamada H.

Nat Commun. 2012 Jan 10;3:622. doi: 10.1038/ncomms1624.

PMID:
22233632
24.

Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor.

Xiang L, Nakamura Y, Lim YM, Yamasaki Y, Kurokawa-Nose Y, Maruyama W, Osawa T, Matsuura A, Motoyama N, Tsuda L.

Aging (Albany NY). 2011 Nov;3(11):1098-109.

25.

In vivo radiobiological characterization of proton beam at the National Cancer Center in Korea: effect of the Chk2 mutation.

Kim SS, Choo DW, Shin D, Baek HJ, Kim TH, Motoyama N, De Coster BM, Gueulette J, Furusawa Y, Ando K, Cho KH.

Int J Radiat Oncol Biol Phys. 2011 Feb 1;79(2):559-62. doi: 10.1016/j.ijrobp.2010.08.010.

PMID:
21195877
26.

Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo.

Niida H, Murata K, Shimada M, Ogawa K, Ohta K, Suzuki K, Fujigaki H, Khaw AK, Banerjee B, Hande MP, Miyamoto T, Miyoshi I, Shirai T, Motoyama N, Delhase M, Appella E, Nakanishi M.

EMBO J. 2010 Oct 20;29(20):3558-70. doi: 10.1038/emboj.2010.218. Epub 2010 Sep 10.

27.

TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.

Naka K, Hoshii T, Muraguchi T, Tadokoro Y, Ooshio T, Kondo Y, Nakao S, Motoyama N, Hirao A.

Nature. 2010 Feb 4;463(7281):676-80. doi: 10.1038/nature08734.

PMID:
20130650
28.

Response of the cutworm Spodoptera litura to sesame leaves or crude extracts in diet.

Ofosuhene Sintim H, Tashiro T, Motoyama N.

J Insect Sci. 2009;9:1-13. doi: 10.1673/031.009.5201.

29.

Bmi1 regulates mitochondrial function and the DNA damage response pathway.

Liu J, Cao L, Chen J, Song S, Lee IH, Quijano C, Liu H, Keyvanfar K, Chen H, Cao LY, Ahn BH, Kumar NG, Rovira II, Xu XL, van Lohuizen M, Motoyama N, Deng CX, Finkel T.

Nature. 2009 May 21;459(7245):387-392. doi: 10.1038/nature08040. Epub 2009 Apr 29.

30.

Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain.

Dohi T, Morita K, Kitayama T, Motoyama N, Morioka N.

Pharmacol Ther. 2009 Jul;123(1):54-79. doi: 10.1016/j.pharmthera.2009.03.018. Epub 2009 Apr 23.

PMID:
19393690
31.

[Gemcitabine treatment in patients with stage IV pancreatic cancer and prognostic factors for survival of patients with stage IVb(a retrospective survey at 15 hospitals in Niigata Prefecture)].

Ohta H, Shioji K, Maruyama Y, Watanabe K, Aiba T, Baba Y, Seki K, Yanagi M, Iiri T, Ishizuka K, Isokawa O, Nakamura A, Natsui M, Furukawa K, Suzuki Y, Ban-Nai H, Motoyama N, Mori S, Aoyagi Y.

Gan To Kagaku Ryoho. 2008 Dec;35(13):2357-61. Japanese.

PMID:
19098402
32.

ATM is required for rapid degradation of cyclin D1 in response to gamma-irradiation.

Choo DW, Baek HJ, Motoyama N, Cho KH, Kim HS, Kim SS.

Biochem Biophys Res Commun. 2009 Jan 23;378(4):847-50. doi: 10.1016/j.bbrc.2008.11.132. Epub 2008 Dec 9.

PMID:
19071090
33.

FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging.

Miyamoto K, Miyamoto T, Kato R, Yoshimura A, Motoyama N, Suda T.

Blood. 2008 Dec 1;112(12):4485-93. doi: 10.1182/blood-2008-05-159848. Epub 2008 Sep 17.

34.

Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice.

Morita K, Motoyama N, Kitayama T, Morioka N, Kifune K, Dohi T.

J Pharmacol Exp Ther. 2008 Aug;326(2):633-45. doi: 10.1124/jpet.108.136267. Epub 2008 Apr 30.

PMID:
18448867
35.

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, Harada M, Motoyama N, Suda T, Hirao A.

Cell Stem Cell. 2007 Jun 7;1(1):101-12. doi: 10.1016/j.stem.2007.02.001.

36.

Strain amplification of the 4k_(F) chain instability in Sr14Cu24O41.

Rusydi A, Abbamonte P, Eisaki H, Fujimaki Y, Smadici S, Motoyama N, Uchida S, Kim YJ, Rübhausen M, Sawatzky GA.

Phys Rev Lett. 2008 Jan 25;100(3):036403. Epub 2008 Jan 25.

PMID:
18233013
37.

Antinociceptive effects of glycine transporter inhibitors in neuropathic pain models in mice.

Morita K, Motoyama N, Kitayama T, Morioka N, Dohi T.

Nihon Yakurigaku Zasshi. 2007 Dec;130(6):458-63. doi: 10.1254/fpj.130.458. Review. Japanese. No abstract available.

PMID:
18079595
38.

The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells.

Ekoff M, Kaufmann T, Engström M, Motoyama N, Villunger A, Jönsson JI, Strasser A, Nilsson G.

Blood. 2007 Nov 1;110(9):3209-17. Epub 2007 Jul 18.

39.

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.

Huntington ND, Puthalakath H, Gunn P, Naik E, Michalak EM, Smyth MJ, Tabarias H, Degli-Esposti MA, Dewson G, Willis SN, Motoyama N, Huang DC, Nutt SL, Tarlinton DM, Strasser A.

Nat Immunol. 2007 Aug;8(8):856-63. Epub 2007 Jul 8.

40.

ER stress triggers apoptosis by activating BH3-only protein Bim.

Puthalakath H, O'Reilly LA, Gunn P, Lee L, Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKimm-Breschkin J, Motoyama N, Gotoh T, Akira S, Bouillet P, Strasser A.

Cell. 2007 Jun 29;129(7):1337-49.

41.

Bcl-2 and Bcl-XL are indispensable for the late phase of mast cell development from mouse embryonic stem cells.

Möller C, Karlberg M, Abrink M, Nakayama KI, Motoyama N, Nilsson G.

Exp Hematol. 2007 Mar;35(3):385-93.

PMID:
17309819
42.

ATR, PML, and CHK2 play a role in arsenic trioxide-induced apoptosis.

Joe Y, Jeong JH, Yang S, Kang H, Motoyama N, Pandolfi PP, Chung JH, Kim MK.

J Biol Chem. 2006 Sep 29;281(39):28764-71. Epub 2006 Aug 3.

43.

ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.

Cao L, Kim S, Xiao C, Wang RH, Coumoul X, Wang X, Li WM, Xu XL, De Soto JA, Takai H, Mai S, Elledge SJ, Motoyama N, Deng CX.

EMBO J. 2006 May 17;25(10):2167-77. Epub 2006 May 4.

44.

DNase II and the Chk2 DNA damage pathway form a genetic barrier blocking replication of horizontally transferred DNA.

Bergsmedh A, Ehnfors J, Kawane K, Motoyama N, Nagata S, Holmgren L.

Mol Cancer Res. 2006 Mar;4(3):187-95.

45.

Ataxia telangiectasia mutated (Atm) knockout mice as a model of osteopenia due to impaired bone formation.

Hishiya A, Ito M, Aburatani H, Motoyama N, Ikeda K, Watanabe K.

Bone. 2005 Oct;37(4):497-503.

PMID:
16027059
46.

SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress.

Kobayashi Y, Furukawa-Hibi Y, Chen C, Horio Y, Isobe K, Ikeda K, Motoyama N.

Int J Mol Med. 2005 Aug;16(2):237-43.

PMID:
16012755
47.

Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage.

Chen C, Shimizu S, Tsujimoto Y, Motoyama N.

Biochem Biophys Res Commun. 2005 Jul 29;333(2):427-31.

PMID:
15950944
48.

FOXO transcription factors in cell-cycle regulation and the response to oxidative stress.

Furukawa-Hibi Y, Kobayashi Y, Chen C, Motoyama N.

Antioxid Redox Signal. 2005 May-Jun;7(5-6):752-60. Review.

PMID:
15890021
49.

Absence of procarboxypeptidase R induces complement-mediated lethal inflammation in lipopolysaccharide-primed mice.

Asai S, Sato T, Tada T, Miyamoto T, Kimbara N, Motoyama N, Okada H, Okada N.

J Immunol. 2004 Oct 1;173(7):4669-74.

50.

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice.

Furuyama T, Kitayama K, Shimoda Y, Ogawa M, Sone K, Yoshida-Araki K, Hisatsune H, Nishikawa S, Nakayama K, Nakayama K, Ikeda K, Motoyama N, Mori N.

J Biol Chem. 2004 Aug 13;279(33):34741-9. Epub 2004 Jun 7.

Supplemental Content

Loading ...
Support Center