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Items: 1 to 50 of 75

1.

Direct acting oral anticoagulants and alopecia: the valuable support of post marketing data.

Bonaldo G, Vaccheri A, Motola D.

Br J Clin Pharmacol. 2020 Jan 16. doi: 10.1111/bcp.14221. [Epub ahead of print]

PMID:
31950530
2.

The prescription of antimicrobials by general practitioners: the differences between north and south Italian provinces.

Bonaldo G, Bianchi S, Ancona D, Procacci C, Natalini N, Motola D, Vaccheri A.

Expert Rev Anti Infect Ther. 2020 Jan 14:1-6. doi: 10.1080/14787210.2020.1713753. [Epub ahead of print]

PMID:
31914829
3.

Cardiovascular safety of macrolide and fluoroquinolone antibiotics: An analysis of the WHO database of adverse drug reactions.

Bonaldo G, Andriani LA, D'Annibali O, Motola D, Vaccheri A.

Pharmacoepidemiol Drug Saf. 2019 Nov;28(11):1457-1463. doi: 10.1002/pds.4873. Epub 2019 Aug 18.

PMID:
31423694
4.

Non-commercial trials on medicines submitted to the Ethics Committee of the University Hospital of Bologna (Italy) along 8 years of activity: time to update rules and recommendations.

Montanaro N, Bonaldo G, Proni S, Chiabrando G, Motola D.

Eur J Clin Pharmacol. 2019 Oct;75(10):1415-1420. doi: 10.1007/s00228-019-02706-0. Epub 2019 Jun 18.

PMID:
31214729
5.

Antibacterial prescription in Italian preschool children: analysis of 7 years of data from the Emilia-Romagna region reimbursement database.

D'Annibali O, Bonaldo G, Donati M, Småbrekke L, Motola D, Vaccheri A.

J Antimicrob Chemother. 2019 Aug 1;74(8):2434-2439. doi: 10.1093/jac/dkz153.

PMID:
30993338
6.

Safety profile of human papilloma virus vaccines: an analysis of the US Vaccine Adverse Event Reporting System from 2007 to 2017.

Bonaldo G, Vaccheri A, D'Annibali O, Motola D.

Br J Clin Pharmacol. 2019 Mar;85(3):634-643. doi: 10.1111/bcp.13841. Epub 2019 Jan 21.

PMID:
30569481
7.

Comparative risk/benefit profile of biosimilar and originator erythropoiesis-stimulating agents (ESAs): data from an Italian observational study in nephrology.

Motola D, Vaccheri A, Roncadori A, Donati M, Bonaldo G, Covezzoli A, Polidori P, Bianchi S.

Eur J Clin Pharmacol. 2018 Jun;74(6):805-810. doi: 10.1007/s00228-018-2428-2. Epub 2018 Feb 10.

PMID:
29429032
8.

Expression of PD-1/PD-L1 and PD-L2 in peripheral T-cells from non-small cell lung cancer patients.

Arrieta O, Montes-Servín E, Hernandez-Martinez JM, Cardona AF, Casas-Ruiz E, Crispín JC, Motola D, Flores-Estrada D, Barrera L.

Oncotarget. 2017 Oct 24;8(60):101994-102005. doi: 10.18632/oncotarget.22025. eCollection 2017 Nov 24.

9.

Antidepressant-Induced Acute Liver Injury: A Case-Control Study in an Italian Inpatient Population.

Ferrajolo C, Scavone C, Donati M, Bortolami O, Stoppa G, Motola D, Vannacci A, Mugelli A, Leone R, Capuano A; DILI-IT Study Group.

Drug Saf. 2018 Jan;41(1):95-102. doi: 10.1007/s40264-017-0583-5.

PMID:
28770534
10.

Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase.

Motola D, Donati M, Biagi C, Calamelli E, Cipriani F, Melis M, Monaco L, Vaccheri A, Ricci G.

Pharmacoepidemiol Drug Saf. 2017 Oct;26(10):1164-1171. doi: 10.1002/pds.4246. Epub 2017 Jun 27.

PMID:
28653802
11.

Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells.

Chen JY, Newcomb B, Zhou C, Pondick JV, Ghoshal S, York SR, Motola DL, Coant N, Yi JK, Mao C, Tanabe KK, Bronova I, Berdyshev EV, Fuchs BC, Hannun Y, Chung RT, Mullen AC.

Sci Rep. 2017 Mar 21;7:44867. doi: 10.1038/srep44867.

12.

Signal detection activity on EudraVigilance data: analysis of the procedure and findings from an Italian Regional Centre for Pharmacovigilance.

Monaco L, Melis M, Biagi C, Donati M, Sapigni E, Vaccheri A, Motola D.

Expert Opin Drug Saf. 2017 Mar;16(3):271-275. doi: 10.1080/14740338.2017.1284200. Epub 2017 Jan 30.

PMID:
28094583
13.

Safety profile of the direct oral anticoagulants: an analysis of the WHO database of adverse drug reactions.

Monaco L, Biagi C, Conti V, Melis M, Donati M, Venegoni M, Vaccheri A, Motola D.

Br J Clin Pharmacol. 2017 Jul;83(7):1532-1543. doi: 10.1111/bcp.13234. Epub 2017 Mar 19.

14.

Six-year activity on approval of compassionate use of medicines by the Ethics Committee of the University Hospital of Bologna (Italy): time to update rules and recommendations.

Montanaro N, Melis M, Proni S, Chiabrando G, Motola D.

Eur J Clin Pharmacol. 2017 Apr;73(4):479-485. doi: 10.1007/s00228-016-2186-y. Epub 2016 Dec 29.

PMID:
28035436
15.

Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C.

Schaefer EA, Meixiong J, Mark C, Deik A, Motola DL, Fusco D, Yang A, Brisac C, Salloum S, Lin W, Clish CB, Peng LF, Chung RT.

World J Gastroenterol. 2016 Dec 7;22(45):9954-9965. doi: 10.3748/wjg.v22.i45.9954.

16.

Ibuprofen-associated hypothermia in children: analysis of the Italian spontaneous reporting database.

Donati M, Monaco L, Melis M, Sottosanti L, Biagi C, Vaccheri A, Motola D.

Eur J Clin Pharmacol. 2016 Oct;72(10):1239-1243. doi: 10.1007/s00228-016-2088-z. Epub 2016 Jul 14.

PMID:
27417946
17.

Long noncoding RNAs expressed in human hepatic stellate cells form networks with extracellular matrix proteins.

Zhou C, York SR, Chen JY, Pondick JV, Motola DL, Chung RT, Mullen AC.

Genome Med. 2016 Mar 23;8(1):31. doi: 10.1186/s13073-016-0285-0.

18.

Risk of acute and serious liver injury associated to nimesulide and other NSAIDs: data from drug-induced liver injury case-control study in Italy.

Donati M, Conforti A, Lenti MC, Capuano A, Bortolami O, Motola D, Moretti U, Vannacci A, Rafaniello C, Vaccheri A, Arzenton E, Bonaiuti R, Sportiello L, Leone R; DILI-IT Study Group.

Br J Clin Pharmacol. 2016 Jul;82(1):238-48. doi: 10.1111/bcp.12938. Epub 2016 Apr 27.

19.

Drug-Induced Progressive Multifocal Leukoencephalopathy: A Comprehensive Analysis of the WHO Adverse Drug Reaction Database.

Melis M, Biagi C, Småbrekke L, Nonino F, Buccellato E, Donati M, Vaccheri A, Motola D.

CNS Drugs. 2015;29(10):879-91. doi: 10.1007/s40263-015-0286-3.

PMID:
26507833
20.

Use of Antibiotics in Pediatrics: 8-Years Survey in Italian Hospitals.

Buccellato E, Melis M, Biagi C, Donati M, Motola D, Vaccheri A.

PLoS One. 2015 Sep 25;10(9):e0139097. doi: 10.1371/journal.pone.0139097. eCollection 2015.

21.

Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability.

Luther J, Garber JJ, Khalili H, Dave M, Bale SS, Jindal R, Motola DL, Luther S, Bohr S, Jeoung SW, Deshpande V, Singh G, Turner JR, Yarmush ML, Chung RT, Patel SJ.

Cell Mol Gastroenterol Hepatol. 2015 Mar;1(2):222-232.

22.

Acute renal failure in patients treated with dronedarone or amiodarone: a large population-based cohort study in Italy.

Conti V, Biagi C, Melis M, Fortino I, Donati M, Vaccheri A, Venegoni M, Motola D.

Eur J Clin Pharmacol. 2015 Sep;71(9):1147-53. doi: 10.1007/s00228-015-1903-2. Epub 2015 Jul 15.

PMID:
26174115
23.

Off-label use of nicardipine as tocolytic and acute pulmonary oedema: a post-marketing analysis of adverse drug reaction reports in EudraVigilance.

Melis M, Cupelli A, Sottosanti L, Buccellato E, Biagi C, Vaccheri A, Motola D.

Pharmacoepidemiol Drug Saf. 2015 Nov;24(11):1220-4. doi: 10.1002/pds.3782. Epub 2015 Apr 2.

PMID:
25845714
24.

Noninvasive Biomarkers of Liver Fibrosis: Clinical Applications and Future Directions.

Motola DL, Caravan P, Chung RT, Fuchs BC.

Curr Pathobiol Rep. 2014 Dec 1;2(4):245-256.

25.

Comparative safety profiles of intravitreal bevacizumab, ranibizumab and pegaptanib: the analysis of the WHO database of adverse drug reactions.

Biagi C, Conti V, Montanaro N, Melis M, Buccellato E, Donati M, Covezzoli A, Amato R, Pazzi L, Venegoni M, Vaccheri A, Motola D.

Eur J Clin Pharmacol. 2014 Dec;70(12):1505-12. doi: 10.1007/s00228-014-1755-1. Epub 2014 Sep 20.

PMID:
25234795
26.

Ten years of pharmacovigilance in Italy: the experience of Emilia-Romagna region in the monitoring of drug's safety profile.

Motola D, Melis M, Lo Bianco S, Buccellato E, Biagi C, Vaccheri A.

Expert Opin Drug Saf. 2014 Jul;13(7):867-73. doi: 10.1517/14740338.2014.916687. Epub 2014 May 8.

PMID:
24809453
27.

Use of antibacterial agents in Italian hospitals: a 2004 to 2011 drug utilization survey in the Emilia-Romagna region.

Buccellato E, Biagi C, Melis M, Lategana R, Motola D, Vaccheri A.

Expert Rev Anti Infect Ther. 2014 Mar;12(3):383-92. doi: 10.1586/14787210.2014.884459. Epub 2014 Feb 3.

PMID:
24484182
28.

Incretin-mimetics associated pancreatitis: evidence from the spontaneous adverse drug reactions reporting in Italy.

Delfino M, Motola D, Benini A, Franzè GP, Barotto M, Campi A, Monda VM.

Expert Opin Drug Saf. 2014 Feb;13(2):151-6. doi: 10.1517/14740338.2014.853036. Epub 2013 Nov 13.

PMID:
24219498
29.

Post-approval safety issues with innovative drugs: a European cohort study.

Mol PG, Arnardottir AH, Motola D, Vrijlandt PJ, Duijnhoven RG, Haaijer-Ruskamp FM, de Graeff PA, Denig P, Straus SM.

Drug Saf. 2013 Nov;36(11):1105-15. doi: 10.1007/s40264-013-0094-y.

PMID:
24048690
30.

[Association between overweight, glucocorticoids and metabolic syndrome in cancer patients under chemotherapy].

Sánchez-Lara K, Hernández D, Motola D, Green D.

Nutr Hosp. 2013 Jan-Feb;28(1):182-7. doi: 10.3305/nh.2013.28.1.6177. Spanish.

31.

Safety profile of antiviral medications: a pharmacovigilance study using the Italian spontaneous-reporting database.

Pugi A, Bonaiuti R, Maggini V, Moschini M, Tuccori M, Leone R, Rossi M, Motola D, Piccinni C, Ferrazin F, Sottosanti L, Mugelli A, Vannacci A, Lapi F.

Am J Health Syst Pharm. 2013 Jun 15;70(12):1039-46. doi: 10.2146/ajhp120665.

PMID:
23719881
32.

Possible occurrence of paraesthesia in patients taking norethisterone: an analysis on the WHO Global Individual Case Reports database (VigiBase).

Buccellato E, Biagi C, Vaccheri A, Melis M, Montanaro N, Motola D.

Expert Opin Drug Saf. 2013 Sep;12(5):615-9. doi: 10.1517/14740338.2013.798298. Epub 2013 May 24.

PMID:
23701188
33.

A TALEN genome-editing system for generating human stem cell-based disease models.

Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA.

Cell Stem Cell. 2013 Feb 7;12(2):238-51. doi: 10.1016/j.stem.2012.11.011. Epub 2012 Dec 13.

34.

Dronedarone-associated acute renal failure: evidence coming from the Italian spontaneous ADR reporting database.

Biagi C, Venegoni M, Melis M, Buccellato E, Montanaro N, Motola D.

Br J Clin Pharmacol. 2013 May;75(5):1351-5. doi: 10.1111/bcp.12005.

35.

Ticlopidine safety profile: a case/non-case study on the basis of the spontaneous ADRs reporting in Italy.

Motola D, Biagi C, Leone R, Venegoni M, Lapi F, Cutroneo P, Vargiu A, Bonaiuti R, Montanaro N, Vaccheri A.

Curr Drug Saf. 2012 Apr;7(2):99-105.

PMID:
22873494
36.

Underreporting in pharmacovigilance: an intervention for Italian GPs (Emilia-Romagna region).

Biagi C, Montanaro N, Buccellato E, Roberto G, Vaccheri A, Motola D.

Eur J Clin Pharmacol. 2013 Feb;69(2):237-44. doi: 10.1007/s00228-012-1321-7. Epub 2012 Jun 17.

PMID:
22706618
37.

Cardiovascular, ocular and bone adverse reactions associated with thiazolidinediones: a disproportionality analysis of the US FDA adverse event reporting system database.

Motola D, Piccinni C, Biagi C, Raschi E, Marra A, Marchesini G, Poluzzi E.

Drug Saf. 2012 Apr 1;35(4):315-23. doi: 10.2165/11596510-000000000-00000.

PMID:
22376166
38.

Statin-associated gynecomastia: evidence coming from the Italian spontaneous ADR reporting database and literature.

Roberto G, Biagi C, Montanaro N, Koci A, Moretti U, Motola D.

Eur J Clin Pharmacol. 2012 Jun;68(6):1007-11. doi: 10.1007/s00228-012-1218-5.

PMID:
22286160
39.

Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes.

Zhi X, Zhou XE, Melcher K, Motola DL, Gelmedin V, Hawdon J, Kliewer SA, Mangelsdorf DJ, Xu HE.

J Biol Chem. 2012 Feb 10;287(7):4894-903. doi: 10.1074/jbc.M111.315242. Epub 2011 Dec 14.

40.

The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity.

Wollam J, Magomedova L, Magner DB, Shen Y, Rottiers V, Motola DL, Mangelsdorf DJ, Cummins CL, Antebi A.

Aging Cell. 2011 Oct;10(5):879-84. doi: 10.1111/j.1474-9726.2011.00733.x. Epub 2011 Aug 7.

41.

Pattern of triptan use and cardiovascular coprescription: a pharmacoepidemiological study in Italy.

Biagi C, Poluzzi E, Roberto G, Puccini A, Vaccheri A, D'Alessandro R, Motola D, Montanaro N.

Eur J Clin Pharmacol. 2011 Dec;67(12):1283-9. doi: 10.1007/s00228-011-1076-6. Epub 2011 Jun 15.

PMID:
21674159
42.

Assessing the association of pioglitazone use and bladder cancer through drug adverse event reporting.

Piccinni C, Motola D, Marchesini G, Poluzzi E.

Diabetes Care. 2011 Jun;34(6):1369-71. doi: 10.2337/dc10-2412. Epub 2011 Apr 22.

43.

Cardiovascular events in statin recipients: impact of adherence to treatment in a 3-year record linkage study.

Poluzzi E, Piccinni C, Carta P, Puccini A, Lanzoni M, Motola D, Vaccheri A, De Ponti F, Montanaro N.

Eur J Clin Pharmacol. 2011 Apr;67(4):407-414. doi: 10.1007/s00228-010-0958-3. Epub 2010 Dec 9.

PMID:
21152908
44.

Safety profile of the fluoroquinolones: analysis of adverse drug reactions in relation to prescription data using four regional pharmacovigilance databases in Italy.

Lapi F, Tuccori M, Motola D, Pugi A, Vietri M, Montanaro N, Vaccheri A, Leoni O, Cocci A, Leone R, Conforti A, Moretti U, Sessa E, Mazzaglia G, Mugelli A, Mazzei T, Vannacci A.

Drug Saf. 2010 Sep 1;33(9):789-99. doi: 10.2165/11536810-000000000-00000.

PMID:
20701411
45.

Identifying adverse drug reactions associated with drug-drug interactions: data mining of a spontaneous reporting database in Italy.

Leone R, Magro L, Moretti U, Cutroneo P, Moschini M, Motola D, Tuccori M, Conforti A.

Drug Saf. 2010 Aug 1;33(8):667-75. doi: 10.2165/11534400-000000000-00000.

PMID:
20635825
46.

Antimicrobials and the risk of torsades de pointes: the contribution from data mining of the US FDA Adverse Event Reporting System.

Poluzzi E, Raschi E, Motola D, Moretti U, De Ponti F.

Drug Saf. 2010 Apr 1;33(4):303-14. doi: 10.2165/11531850-000000000-00000.

PMID:
20297862
47.

Stronger association of drug-induced progressive multifocal leukoencephalopathy (PML) with biological immunomodulating agents.

Piccinni C, Sacripanti C, Poluzzi E, Motola D, Magro L, Moretti U, Conforti A, Montanaro N.

Eur J Clin Pharmacol. 2010 Feb;66(2):199-206. doi: 10.1007/s00228-009-0739-z. Epub 2009 Oct 17.

PMID:
19838692
48.

Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.

Wang Z, Zhou XE, Motola DL, Gao X, Suino-Powell K, Conneely A, Ogata C, Sharma KK, Auchus RJ, Lok JB, Hawdon JM, Kliewer SA, Xu HE, Mangelsdorf DJ.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9138-43. doi: 10.1073/pnas.0904064106. Epub 2009 Jun 2.

49.

Synthesis and activity of dafachronic acid ligands for the C. elegans DAF-12 nuclear hormone receptor.

Sharma KK, Wang Z, Motola DL, Cummins CL, Mangelsdorf DJ, Auchus RJ.

Mol Endocrinol. 2009 May;23(5):640-8. doi: 10.1210/me.2008-0415. Epub 2009 Feb 5.

50.

Statin-associated psychiatric adverse events: a case/non-case evaluation of an Italian database of spontaneous adverse drug reaction reporting.

Tuccori M, Lapi F, Testi A, Coli D, Moretti U, Vannacci A, Motola D, Salvo F, Rivolta AL, Blandizzi C, Mugelli A, Del Tacca M.

Drug Saf. 2008;31(12):1115-23. doi: 10.2165/0002018-200831120-00007.

PMID:
19026028

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