Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 140

1.

Skeletal muscle function and need for long-term care of urban elderly people in Japan (the Bunkyo Health Study): a prospective cohort study.

Someya Y, Tamura Y, Kaga H, Nojiri S, Shimada K, Daida H, Ishijima M, Kaneko K, Aoki S, Miida T, Hirayama S, Konishi S, Hattori N, Motoi Y, Naito H, Kawamori R, Watada H.

BMJ Open. 2019 Sep 17;9(9):e031584. doi: 10.1136/bmjopen-2019-031584.

2.

Detection of lesions depends on the DARTEL template used in group comparisons with voxel-based morphometry.

Goto M, Kamatgata K, Saito A, Abe O, Motoi Y, Miyajima M, Nakajima M.

Acta Radiol. 2019 Jul 2:284185119855735. doi: 10.1177/0284185119855735. [Epub ahead of print] No abstract available.

PMID:
31265318
3.

Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism.

Nakayama S, Shimonaka S, Elahi M, Nishioka K, Oji Y, Matsumoto SE, Li Y, Yoshino H, Mogushi K, Hatano T, Sato T, Ikura T, Ito N, Motoi Y, Hattori N.

Neurobiol Aging. 2019 Dec;84:240.e13-240.e22. doi: 10.1016/j.neurobiolaging.2019.02.016. Epub 2019 Mar 1.

PMID:
31027853
4.

Cytidine deaminase enables Toll-like receptor 8 activation by cytidine or its analogs.

Furusho K, Shibata T, Sato R, Fukui R, Motoi Y, Zhang Y, Saitoh SI, Ichinohe T, Moriyama M, Nakamura S, Miyake K.

Int Immunol. 2019 Mar 5;31(3):167-173. doi: 10.1093/intimm/dxy075.

PMID:
30535046
5.

Soluble LR11 competes with amyloid β in binding to cerebrospinal fluid-high-density lipoprotein.

Yano K, Hirayama S, Misawa N, Furuta A, Ueno T, Motoi Y, Seino U, Ebinuma H, Ikeuchi T, Schneider WJ, Bujo H, Miida T.

Clin Chim Acta. 2019 Feb;489:29-34. doi: 10.1016/j.cca.2018.11.024. Epub 2018 Nov 15.

PMID:
30448281
6.

RNA-seq analysis reveals considerable genetic diversity and provides genetic markers saturating all chromosomes in the diploid wild wheat relative Aegilops umbellulata.

Okada M, Yoshida K, Nishijima R, Michikawa A, Motoi Y, Sato K, Takumi S.

BMC Plant Biol. 2018 Nov 8;18(1):271. doi: 10.1186/s12870-018-1498-8.

7.

Neutropenia related to an azathioprine metabolic disorder induced by an inosine triphosphate pyrophosphohydrolase (ITPA) gene mutation in a patient with PR3-ANCA-positive microscopic polyangiitis
.

Honda K, Kobayashi A, Niikura T, Hasegawa T, Saito Z, Ito S, Sasaki T, Komine K, Ishizuka S, Motoi Y, Kubota T, Yamamoto H, Yokoo T.

Clin Nephrol. 2018 Nov;90(5):363-369. doi: 10.5414/CN109383.

PMID:
30106365
8.

Marked Reduction in the Striatal Dopamine Transporter Uptake During the Early Stage of Motor Symptoms in Patients with the MAPT N279K Mutation.

Takeshige H, Nakayama S, Nishioka K, Li Y, Motoi Y, Hattori N.

Intern Med. 2018 Oct 15;57(20):3015-3019. doi: 10.2169/internalmedicine.0454-17. Epub 2018 Jun 6.

9.

Change of Amyloid-β 1-42 Toxic Conformer Ratio After Cerebrospinal Fluid Diversion Predicts Long-Term Cognitive Outcome in Patients with Idiopathic Normal Pressure Hydrocephalus.

Akiba C, Nakajima M, Miyajima M, Ogino I, Motoi Y, Kawamura K, Adachi S, Kondo A, Sugano H, Tokuda T, Irie K, Arai H.

J Alzheimers Dis. 2018;63(3):989-1002. doi: 10.3233/JAD-180059.

10.

Neurite orientation dispersion and density imaging of the nigrostriatal pathway in Parkinson's disease: Retrograde degeneration observed by tract-profile analysis.

Andica C, Kamagata K, Hatano T, Okuzumi A, Saito A, Nakazawa M, Ueda R, Motoi Y, Kamiya K, Suzuki M, Hori M, Kumamaru KK, Hattori N, Aoki S.

Parkinsonism Relat Disord. 2018 Jun;51:55-60. doi: 10.1016/j.parkreldis.2018.02.046. Epub 2018 Feb 28.

11.

Digital PCR for determination of cytochrome P450 2D6 and sulfotransferase 1A1 gene copy number variations.

Motoi Y, Watanabe K, Honma H, Tadano Y, Hashimoto H, Kubota T.

Drug Discov Ther. 2017;11(6):336-341. doi: 10.5582/ddt.2017.01057.

12.

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos.

Oka M, Hashimoto K, Yamaguchi Y, Saitoh SI, Sugiura Y, Motoi Y, Honda K, Kikko Y, Ohata S, Suematsu M, Miura M, Miyake K, Katada T, Kontani K.

J Cell Sci. 2017 Oct 15;130(20):3568-3577. doi: 10.1242/jcs.200519. Epub 2017 Aug 21.

13.

Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.

Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi-Miyamoto T, Fukui R, Tanimura N, Motoi Y, Akashi-Takamura S, Kato T, Fujishita S, Kimura T, Ohto U, Shimizu T, Hirokawa T, Miyake K, Fukase K, Fujimoto Y, Nagai Y, Takatsu K.

J Biol Chem. 2017 Sep 15;292(37):15378-15394. doi: 10.1074/jbc.M117.791780. Epub 2017 Jul 28.

14.

Identification of biomarker sets for predicting the efficacy of sublingual immunotherapy against pollen-induced allergic rhinitis.

Gotoh M, Kaminuma O, Nakaya A, Katayama K, Motoi Y, Watanabe N, Saeki M, Nishimura T, Kitamura N, Yamaoka K, Okubo K, Hiroi T.

Int Immunol. 2017 Jun 1;29(6):291-300. doi: 10.1093/intimm/dxx034.

PMID:
28575522
15.

Age-related effects and gender differences in Japanese healthy controls for [123I] FP-CIT SPECT.

Yamamoto H, Arimura S, Nakanishi A, Shimo Y, Motoi Y, Ishiguro K, Murakami K, Hattori N, Aoki S.

Ann Nucl Med. 2017 Jun;31(5):407-412. doi: 10.1007/s12149-017-1168-1. Epub 2017 Apr 5.

PMID:
28382589
16.

The protective effect of the anti-Toll-like receptor 9 antibody against acute cytokine storm caused by immunostimulatory DNA.

Murakami Y, Fukui R, Motoi Y, Shibata T, Saitoh SI, Sato R, Miyake K.

Sci Rep. 2017 Mar 7;7:44042. doi: 10.1038/srep44042.

17.

Galantamine Response Associates with Agitation and the Prefrontal Cortex in Patients with Alzheimer's Disease.

Nakayama S, Suda A, Nakanishi A, Motoi Y, Hattori N.

J Alzheimers Dis. 2017;57(1):267-273. doi: 10.3233/JAD-160902.

PMID:
28222509
18.

Genotype-phenotype correlations of cysteine replacement in CADASIL.

Matsushima T, Conedera S, Tanaka R, Li Y, Yoshino H, Funayama M, Ikeda A, Hosaka Y, Okuzumi A, Shimada Y, Yamashiro K, Motoi Y, Nishioka K, Hattori N.

Neurobiol Aging. 2017 Feb;50:169.e7-169.e14. doi: 10.1016/j.neurobiolaging.2016.10.026. Epub 2016 Nov 2.

PMID:
27890607
19.

Genetic association between RAGE polymorphisms and Alzheimer's disease and Lewy body dementias in a Japanese cohort: a case-control study.

Takeshita Y, Shibata N, Kasanuki K, Nagata T, Shinagawa S, Kobayashi N, Ohnuma T, Suzuki A, Kawai E, Takayama T, Nishioka K, Motoi Y, Hattori N, Nakayama K, Yamada H, Arai H.

Int J Geriatr Psychiatry. 2017 Dec;32(12):1241-1246. doi: 10.1002/gps.4600. Epub 2016 Oct 4.

PMID:
27699858
20.

Involvement of the Septo-Hippocampal Cholinergic Pathway in Association with Septal Acetylcholinesterase Upregulation in a Mouse Model of Tauopathy.

Hara Y, Motoi Y, Hikishima K, Mizuma H, Onoe H, Matsumoto SE, Elahi M, Okano H, Aoki S, Hattori N.

Curr Alzheimer Res. 2017;14(1):94-103.

PMID:
27335039
21.

Genome-wide identification of novel genetic markers from RNA sequencing assembly of diverse Aegilops tauschii accessions.

Nishijima R, Yoshida K, Motoi Y, Sato K, Takumi S.

Mol Genet Genomics. 2016 Aug;291(4):1681-94. doi: 10.1007/s00438-016-1211-2. Epub 2016 May 3.

PMID:
27142109
22.

Genetic Association between Presenilin 2 Polymorphisms and Alzheimer's Disease and Dementia of Lewy Body Type in a Japanese Population.

Suzuki A, Shibata N, Kasanuki K, Nagata T, Shinagawa S, Kobayashi N, Ohnuma T, Takeshita Y, Kawai E, Takayama T, Nishioka K, Motoi Y, Hattori N, Nakayama K, Yamada H, Arai H.

Dement Geriatr Cogn Dis Extra. 2016 Mar 16;6(1):90-7. doi: 10.1159/000444080. eCollection 2016 Jan-Apr.

23.

Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8.

Tanji H, Ohto U, Motoi Y, Shibata T, Miyake K, Shimizu T.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3012-7. doi: 10.1073/pnas.1516000113. Epub 2016 Feb 29.

24.

Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice.

Elahi M, Hasan Z, Motoi Y, Matsumoto SE, Ishiguro K, Hattori N.

J Alzheimers Dis. 2016;51(4):1209-24. doi: 10.3233/JAD-150820.

PMID:
26923011
25.

Improvement of barley genome annotations by deciphering the Haruna Nijo genome.

Sato K, Tanaka T, Shigenobu S, Motoi Y, Wu J, Itoh T.

DNA Res. 2016 Feb;23(1):21-8. doi: 10.1093/dnares/dsv033. Epub 2015 Nov 29.

26.

Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice.

Elahi M, Motoi Y, Matsumoto SE, Hasan Z, Ishiguro K, Hattori N.

Neurosci Lett. 2016 Jan 1;610:207-12. doi: 10.1016/j.neulet.2015.11.010. Epub 2015 Nov 27.

PMID:
26592481
27.

Neurite orientation dispersion and density imaging in the substantia nigra in idiopathic Parkinson disease.

Kamagata K, Hatano T, Okuzumi A, Motoi Y, Abe O, Shimoji K, Kamiya K, Suzuki M, Hori M, Kumamaru KK, Hattori N, Aoki S.

Eur Radiol. 2016 Aug;26(8):2567-77. doi: 10.1007/s00330-015-4066-8. Epub 2015 Oct 29.

PMID:
26515546
28.

Guanosine and its modified derivatives are endogenous ligands for TLR7.

Shibata T, Ohto U, Nomura S, Kibata K, Motoi Y, Zhang Y, Murakami Y, Fukui R, Ishimoto T, Sano S, Ito T, Shimizu T, Miyake K.

Int Immunol. 2016 May;28(5):211-22. doi: 10.1093/intimm/dxv062. Epub 2015 Oct 20.

29.

The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties.

Matsumoto SE, Motoi Y, Ishiguro K, Tabira T, Kametani F, Hasegawa M, Hattori N.

Hum Mol Genet. 2015 Nov 15;24(22):6403-16. doi: 10.1093/hmg/ddv351. Epub 2015 Sep 15.

PMID:
26374846
30.

Fibromyalgia syndrome and cognitive dysfunction in elderly: a case series.

Nishioka K, Hayashi T, Suzuki M, Li Y, Nakayama S, Matsushima T, Usui C, Shibata N, Motoi Y, Tanaka R, Nishioka K, Hattori N.

Int J Rheum Dis. 2016 Jan;19(1):21-9. doi: 10.1111/1756-185X.12734. Epub 2015 Sep 10.

PMID:
26354322
31.

Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.

Kanno A, Tanimura N, Ishizaki M, Ohko K, Motoi Y, Onji M, Fukui R, Shimozato T, Yamamoto K, Shibata T, Sano S, Sugahara-Tobinai A, Takai T, Ohto U, Shimizu T, Saitoh S, Miyake K.

Nat Commun. 2015 Feb 4;6:6119. doi: 10.1038/ncomms7119.

PMID:
25648980
32.

Roles of the cleaved N-terminal TLR3 fragment and cell surface TLR3 in double-stranded RNA sensing.

Murakami Y, Fukui R, Motoi Y, Kanno A, Shibata T, Tanimura N, Saitoh S, Miyake K.

J Immunol. 2014 Nov 15;193(10):5208-17. doi: 10.4049/jimmunol.1400386. Epub 2014 Oct 10.

33.

Lipopeptides are signaled by Toll-like receptor 1, 2 and 6 in endolysosomes.

Motoi Y, Shibata T, Takahashi K, Kanno A, Murakami Y, Li X, Kasahara T, Miyake K.

Int Immunol. 2014 Oct;26(10):563-73. doi: 10.1093/intimm/dxu054. Epub 2014 May 24.

PMID:
24860120
34.

Selective suppression of Th2 cell-mediated lung eosinophilic inflammation by anti-major facilitator super family domain containing 10 monoclonal antibody.

Nishimura T, Saeki M, Motoi Y, Kitamura N, Mori A, Kaminuma O, Hiroi T.

Allergol Int. 2014 May;63 Suppl 1:29-35. doi: 10.2332/allergolint.13-OA-0635.

35.

Lithium and autophagy.

Motoi Y, Shimada K, Ishiguro K, Hattori N.

ACS Chem Neurosci. 2014 Jun 18;5(6):434-42. doi: 10.1021/cn500056q. Epub 2014 Apr 30. Review.

36.

Effects of donepezil dose escalation in Parkinson's patients with dementia receiving long-term donepezil treatment: an exploratory study.

Ishikawa K, Motoi Y, Mizuno Y, Kubo S, Hattori N.

Psychogeriatrics. 2014 Jun;14(2):93-100. doi: 10.1111/psyg.12045. Epub 2014 Mar 24.

37.

A preliminary diffusional kurtosis imaging study of Parkinson disease: comparison with conventional diffusion tensor imaging.

Kamagata K, Tomiyama H, Hatano T, Motoi Y, Abe O, Shimoji K, Kamiya K, Suzuki M, Hori M, Yoshida M, Hattori N, Aoki S.

Neuroradiology. 2014 Mar;56(3):251-8. doi: 10.1007/s00234-014-1327-1. Epub 2014 Jan 28.

PMID:
24468858
38.

Diffusional kurtosis imaging analysis in patients with hypertension.

Shimoji K, Uka T, Tamura Y, Yoshida M, Kamagata K, Hori M, Motoi Y, Watada H, Kawamori R, Aoki S.

Jpn J Radiol. 2014 Feb;32(2):98-104. doi: 10.1007/s11604-013-0275-8. Epub 2014 Jan 11.

PMID:
24414884
39.

Leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex.

Miyajima M, Nakajima M, Motoi Y, Moriya M, Sugano H, Ogino I, Nakamura E, Tada N, Kunichika M, Arai H.

PLoS One. 2013 Sep 18;8(9):e74453. doi: 10.1371/journal.pone.0074453. eCollection 2013.

40.

Verbal dysflucency as a consequence of basal ganglia infarction with selective involvement of dorsolateral prefrontal fiber tract.

Nakayama S, Kamagata K, Sano T, Shimada Y, Tanaka Y, Fukui T, Urabe T, Aoki S, Hattori N, Motoi Y.

J Neurol. 2013 Sep;260(9):2427-9. doi: 10.1007/s00415-013-7066-0. Epub 2013 Aug 23. No abstract available.

PMID:
23974644
41.

Diffusional kurtosis imaging of cingulate fibers in Parkinson disease: comparison with conventional diffusion tensor imaging.

Kamagata K, Tomiyama H, Motoi Y, Kano M, Abe O, Ito K, Shimoji K, Suzuki M, Hori M, Nakanishi A, Kuwatsuru R, Sasai K, Aoki S, Hattori N.

Magn Reson Imaging. 2013 Nov;31(9):1501-6. doi: 10.1016/j.mri.2013.06.009. Epub 2013 Jul 27.

PMID:
23895870
42.

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing.

Onji M, Kanno A, Saitoh S, Fukui R, Motoi Y, Shibata T, Matsumoto F, Lamichhane A, Sato S, Kiyono H, Yamamoto K, Miyake K.

Nat Commun. 2013;4:1949. doi: 10.1038/ncomms2949.

PMID:
23752491
43.

Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia.

Shibata N, Motoi Y, Tomiyama H, Ohnuma T, Kuerban B, Tomson K, Komatsu M, Shimazaki H, Hattori N, Arai H.

Dement Geriatr Cogn Dis Extra. 2013 May 18;3(1):161-7. doi: 10.1159/000351419. Print 2013 Jan.

44.

Defining the culture and attitude towards dietary management actions in people undergoing haemodialysis.

Onbe H, Oka M, Shimada M, Motegi E, Motoi Y, Okabe A.

J Ren Care. 2013 Jun;39(2):90-5. doi: 10.1111/j.1755-6686.2013.12011.x.

PMID:
23683303
45.

Obesity-associated autoantibody production requires AIM to retain the immunoglobulin M immune complex on follicular dendritic cells.

Arai S, Maehara N, Iwamura Y, Honda S, Nakashima K, Kai T, Ogishi M, Morita K, Kurokawa J, Mori M, Motoi Y, Miyake K, Matsuhashi N, Yamamura K, Ohara O, Shibuya A, Wakeland EK, Li QZ, Miyazaki T.

Cell Rep. 2013 Apr 25;3(4):1187-98. doi: 10.1016/j.celrep.2013.03.006. Epub 2013 Apr 4.

46.

Essential role for Toll-like receptor 7 (TLR7)-unique cysteines in an intramolecular disulfide bond, proteolytic cleavage and RNA sensing.

Kanno A, Yamamoto C, Onji M, Fukui R, Saitoh S, Motoi Y, Shibata T, Matsumoto F, Muta T, Miyake K.

Int Immunol. 2013 Jul;25(7):413-22. doi: 10.1093/intimm/dxt007. Epub 2013 Feb 26.

PMID:
23446849
47.

Relationship between cognitive impairment and white-matter alteration in Parkinson's disease with dementia: tract-based spatial statistics and tract-specific analysis.

Kamagata K, Motoi Y, Tomiyama H, Abe O, Ito K, Shimoji K, Suzuki M, Hori M, Nakanishi A, Sano T, Kuwatsuru R, Sasai K, Aoki S, Hattori N.

Eur Radiol. 2013 Jul;23(7):1946-55. doi: 10.1007/s00330-013-2775-4. Epub 2013 Feb 13.

48.

[Development of antibodies for immunotherapy of Alzheimer's disease].

Matsumoto SE, Jin H, Takeda K, Hasegawa Y, Motoi Y, Hattori N, Tabira T.

Rinsho Shinkeigaku. 2012;52(11):1168-70. Japanese.

PMID:
23196552
49.

Detection of Rickettsia tamurae DNA in ticks and wild boar (Sus scrofa leucomystax) skins in Shimane Prefecture, Japan.

Motoi Y, Asano M, Inokuma H, Ando S, Kawabata H, Takano A, Suzuki M.

J Vet Med Sci. 2013;75(3):263-7. Epub 2012 Oct 16.

50.

PRAT4A-dependent expression of cell surface TLR5 on neutrophils, classical monocytes and dendritic cells.

Shibata T, Takemura N, Motoi Y, Goto Y, Karuppuchamy T, Izawa K, Li X, Akashi-Takamura S, Tanimura N, Kunisawa J, Kiyono H, Akira S, Kitamura T, Kitaura J, Uematsu S, Miyake K.

Int Immunol. 2012 Oct;24(10):613-23. Epub 2012 Jul 25.

PMID:
22836022

Supplemental Content

Support Center