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Items: 1 to 50 of 163

1.

Immunological Features of a Lung Cancer Patient Achieving an Objective Response with Anti-PD-1 Blockade Therapy.

Kamata T, Yoshida S, Takami M, Ihara F, Yoshizawa H, Toyoda T, Takeshita Y, Nobuyama S, Kanetsuna Y, Sato T, Yoshino I, Motohashi S.

Cancer Sci. 2019 Nov 2. doi: 10.1111/cas.14222. [Epub ahead of print]

2.

Regulatory T cells induce CD4- NKT cell anergy and suppress NKT cell cytotoxic function.

Ihara F, Sakurai D, Takami M, Kamata T, Kunii N, Yamasaki K, Iinuma T, Nakayama T, Motohashi S, Okamoto Y.

Cancer Immunol Immunother. 2019 Oct 22. doi: 10.1007/s00262-019-02417-6. [Epub ahead of print]

PMID:
31641795
3.

Deep Circumflex Iliac Artery as an Inflow Alternative for Surgical Revascularization: A Case Report.

Haga M, Motohashi S, Inoue H, Akasaka J, Shindo S.

Vasc Endovascular Surg. 2019 Sep 23:1538574419877730. doi: 10.1177/1538574419877730. [Epub ahead of print]

PMID:
31547785
4.

A Double-Blind Randomized Controlled Trial to Determine the Preventive Effect of Hangekobokuto on Aspiration Pneumonia in Patients Undergoing Cardiovascular Surgery.

Kawago K, Nishibe T, Shindo S, Inoue H, Motohashi S, Akasaka J, Ogino H.

Ann Thorac Cardiovasc Surg. 2019 Jul 18. doi: 10.5761/atcs.oa.19-00128. [Epub ahead of print]

5.

Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation.

Harada K, Ihara F, Takami M, Kamata T, Mise N, Yoshizawa H, Hishiki T, Saito T, Terui K, Nakata M, Komatsu S, Ikeuchi T, Nakayama T, Yoshida H, Motohashi S.

Cancer Sci. 2019 Mar;110(3):888-902. doi: 10.1111/cas.13933. Epub 2019 Feb 1.

6.

Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer.

Makita Y, Kunii N, Sakurai D, Ihara F, Motohashi S, Suzuki A, Nakayama T, Okamoto Y.

BMC Cancer. 2018 Dec 17;18(1):1254. doi: 10.1186/s12885-018-5179-7.

7.

Role of leukotriene B4 12-hydroxydehydrogenase in α-galactosylceramide-pulsed dendritic cell therapy for non-small cell lung cancer.

Tanaka K, Kanesaka Y, Takami M, Suzuki A, Hosokawa H, Onodera A, Kamata T, Nagato K, Nakayama T, Yoshino I, Motohashi S.

Biochem Biophys Res Commun. 2018 Nov 17;506(1):27-32. doi: 10.1016/j.bbrc.2018.10.048. Epub 2018 Oct 15.

PMID:
30336981
8.

TGF-β suppresses RasGRP1 expression and supports regulatory T cell resistance against p53-induced CD28-dependent T-cell apoptosis.

Takami M, Cunha C, Motohashi S, Nakayama T, Iwashima M.

Eur J Immunol. 2018 Dec;48(12):1938-1943. doi: 10.1002/eji.201847587. Epub 2018 Oct 24.

PMID:
30298904
9.

Clinical Application of iNKT Cell-mediated Anti-tumor Activity Against Lung Cancer and Head and Neck Cancer.

Takami M, Ihara F, Motohashi S.

Front Immunol. 2018 Sep 7;9:2021. doi: 10.3389/fimmu.2018.02021. eCollection 2018. Review.

10.

CD69 prevents PLZFhi innate precursors from prematurely exiting the thymus and aborting NKT2 cell differentiation.

Kimura MY, Igi A, Hayashizaki K, Mita Y, Shinzawa M, Kadakia T, Endo Y, Ogawa S, Yagi R, Motohashi S, Singer A, Nakayama T.

Nat Commun. 2018 Sep 14;9(1):3749. doi: 10.1038/s41467-018-06283-1.

11.

Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-infiltrating T cells.

Mita Y, Kimura MY, Hayashizaki K, Koyama-Nasu R, Ito T, Motohashi S, Okamoto Y, Nakayama T.

Int Immunol. 2018 Nov 14;30(12):559-567. doi: 10.1093/intimm/dxy050.

PMID:
30085193
12.

Immunosuppressive property of submandibular lymph nodes in patients with head and neck tumors: differential distribution of regulatory T cells.

Sakurai D, Uchida R, Ihara F, Kunii N, Nakagawa T, Chazono H, Hanazawa T, Motohashi S, Okamoto Y.

BMC Res Notes. 2018 Jul 16;11(1):479. doi: 10.1186/s13104-018-3587-z.

13.

Accuracy analysis of computer-assisted surgery for femoral trochanteric fracture using a fluoroscopic navigation system: Stryker ADAPT® system.

Takai H, Murayama M, Kii S, Mito D, Hayai C, Motohashi S, Takahashi T.

Injury. 2018 Jun;49(6):1149-1154. doi: 10.1016/j.injury.2018.03.014. Epub 2018 Mar 19.

14.

Double-Stranded RNA Derived from Lactic Acid Bacteria Augments Th1 Immunity via Interferon-β from Human Dendritic Cells.

Kawashima T, Ikari N, Watanabe Y, Kubota Y, Yoshio S, Kanto T, Motohashi S, Shimojo N, Tsuji NM.

Front Immunol. 2018 Jan 23;9:27. doi: 10.3389/fimmu.2018.00027. eCollection 2018.

15.

Clinical Significance of the Serotonin Release Assay and Platelet Count Monitoring After Cardiac Surgery.

Motohashi S, Matsuo T, Inoue H, Kaneko M, Shindo S.

Clin Appl Thromb Hemost. 2018 Sep;24(6):944-949. doi: 10.1177/1076029617734308. Epub 2017 Oct 18.

16.

Invariant natural killer T infiltration in neuroblastoma with favorable outcome.

Hishiki T, Mise N, Harada K, Ihara F, Takami M, Saito T, Terui K, Nakata M, Komatsu S, Yoshida H, Motohashi S.

Pediatr Surg Int. 2018 Feb;34(2):195-201. doi: 10.1007/s00383-017-4189-x. Epub 2017 Oct 10.

PMID:
29018959
17.

Frequency and proliferative response of circulating invariant natural killer T cells in pediatric patients with malignant solid tumors.

Hishiki T, Mise N, Harada K, Ihara F, Takami M, Saito T, Terui K, Nakata M, Komatsu S, Yoshida H, Motohashi S.

Pediatr Surg Int. 2018 Feb;34(2):169-176. doi: 10.1007/s00383-017-4185-1. Epub 2017 Oct 10.

PMID:
29018953
18.

[II. Overview and Future Outlook of Immune Cell Therapy for Lung Cancer].

Ihara F, Motohashi S.

Gan To Kagaku Ryoho. 2017 Aug;44(8):650-654. Japanese. No abstract available.

PMID:
28860435
19.

Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation.

Hayashizaki K, Kimura MY, Tokoyoda K, Hosokawa H, Shinoda K, Hirahara K, Ichikawa T, Onodera A, Hanazawa A, Iwamura C, Kakuta J, Muramoto K, Motohashi S, Tumes DJ, Iinuma T, Yamamoto H, Ikehara Y, Okamoto Y, Nakayama T.

Sci Immunol. 2016 Sep 16;1(3):eaaf9154. doi: 10.1126/sciimmunol.aaf9154. Epub 2016 Sep 16.

PMID:
28783682
20.

Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation.

Kimura MY, Hayashizaki K, Tokoyoda K, Takamura S, Motohashi S, Nakayama T.

Immunol Rev. 2017 Jul;278(1):87-100. doi: 10.1111/imr.12559. Review.

PMID:
28658550
21.

Isolation, Amino Acid Sequences, and Plausible Functions of the Galacturonic Acid-Binding Egg Lectin of the Sea Hare Aplysia kurodai.

Motohashi S, Jimbo M, Naito T, Suzuki T, Sakai R, Kamiya H.

Mar Drugs. 2017 Jun 2;15(6). pii: E161. doi: 10.3390/md15060161.

22.

CD45RA-Foxp3high regulatory T cells have a negative impact on the clinical outcome of head and neck squamous cell carcinoma.

Ihara F, Sakurai D, Horinaka A, Makita Y, Fujikawa A, Sakurai T, Yamasaki K, Kunii N, Motohashi S, Nakayama T, Okamoto Y.

Cancer Immunol Immunother. 2017 Oct;66(10):1275-1285. doi: 10.1007/s00262-017-2021-z. Epub 2017 May 27.

PMID:
28551813
23.

Invariant NKT cell-based immunotherapy for lung cancer and head and neck cancer.

Ihara F, Motohashi S.

Nihon Rinsho. 2017 Feb;75(2):312-316. Japanese.

PMID:
30562870
24.

Spontaneous Evacuation of a Vascular Metallic Stent through a Graft-Duodenal Fistula with Concomitant Non-Surgical Fistula Closure.

Shindo S, Inoue H, Motohashi S, Uchiyama H, Akasaka J.

Ann Vasc Dis. 2016;9(4):338-341. doi: 10.3400/avd.cr.16-00068. Epub 2016 Nov 15.

25.

The Effect of Hachimi-Jio-Gan (Ba-Wei-Di-Huang-Wan) on the Quality of Life in Patients with Peripheral Arterial Disease - A Prospective Study Using Kampo Medicine.

Kawago K, Shindo S, Inoue H, Akasaka J, Motohashi S, Urabe G, Sato M, Uchiyama H, Ogino H.

Ann Vasc Dis. 2016;9(4):289-294. doi: 10.3400/avd.oa.15-00133. Epub 2016 Sep 15.

26.

Blockade of programmed death-1/programmed death ligand pathway enhances the antitumor immunity of human invariant natural killer T cells.

Kamata T, Suzuki A, Mise N, Ihara F, Takami M, Makita Y, Horinaka A, Harada K, Kunii N, Yoshida S, Yoshino I, Nakayama T, Motohashi S.

Cancer Immunol Immunother. 2016 Dec;65(12):1477-1489. Epub 2016 Sep 15.

27.

Low Frequency of Programmed Death Ligand 1 Expression in Pediatric Cancers.

Aoki T, Hino M, Koh K, Kyushiki M, Kishimoto H, Arakawa Y, Hanada R, Kawashima H, Kurihara J, Shimojo N, Motohashi S.

Pediatr Blood Cancer. 2016 Aug;63(8):1461-4. doi: 10.1002/pbc.26018. Epub 2016 May 2.

28.

Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells.

Hosokawa H, Tanaka T, Endo Y, Kato M, Shinoda K, Suzuki A, Motohashi S, Matsumoto M, Nakayama KI, Nakayama T.

Nat Commun. 2016 Apr 7;7:11289. doi: 10.1038/ncomms11289.

29.

Skin Permeation of Testosterone from Viscoelastic Lecithin Reverse Wormlike Micellar Solution.

Imai M, Hashizaki K, Yanagi A, Taguchi H, Saito Y, Motohashi S, Fujii M.

Biol Pharm Bull. 2016;39(4):532-9. doi: 10.1248/bpb.b15-00750.

30.

Antibody-dependent cellular cytotoxicity toward neuroblastoma enhanced by activated invariant natural killer T cells.

Mise N, Takami M, Suzuki A, Kamata T, Harada K, Hishiki T, Saito T, Terui K, Mitsunaga T, Nakata M, Ikeuchi T, Nakayama T, Yoshida H, Motohashi S.

Cancer Sci. 2016 Mar;107(3):233-41. doi: 10.1111/cas.12882. Epub 2016 Feb 9.

31.

Invariant NKT cells are resistant to circulating CD15+ myeloid-derived suppressor cells in patients with head and neck cancer.

Horinaka A, Sakurai D, Ihara F, Makita Y, Kunii N, Motohashi S, Nakayama T, Okamoto Y.

Cancer Sci. 2016 Mar;107(3):207-16. doi: 10.1111/cas.12866. Epub 2016 Feb 13.

32.

[Corrigendum] Aberrant methylation of CXCL12 in non-small cell lung cancer is associated with an unfavorable prognosis.

Suzuki M, Mohamed S, Nakajima T, Kubo R, Tian L, Fujiwara T, Suzuki H, Nagato K, Chiyo M, Motohashi S, Yasufuku K, Iyoda A, Yoshida S, Sekine Y, Shibuya K, Hiroshima K, Nakatani Y, Yoshino I, Fujisawa T.

Int J Oncol. 2015 Aug;47(2):791. doi: 10.3892/ijo.2015.3046. Epub 2015 Jun 12. No abstract available.

PMID:
26081105
33.

Methylation of Gata3 protein at Arg-261 regulates transactivation of the Il5 gene in T helper 2 cells.

Hosokawa H, Kato M, Tohyama H, Tamaki Y, Endo Y, Kimura MY, Tumes DJ, Motohashi S, Matsumoto M, Nakayama KI, Tanaka T, Nakayama T.

J Biol Chem. 2015 May 22;290(21):13095-103. doi: 10.1074/jbc.M114.621524. Epub 2015 Apr 10.

34.

Effects of albumin binding on photocytotoxicity of extracellular photosensitization reaction using talaporfin sodium to rat myocardial cells.

Ogawa E, Motohashi S, Ito A, Arai T.

Photodiagnosis Photodyn Ther. 2015 Jun;12(2):252-7. doi: 10.1016/j.pdpdt.2015.02.001. Epub 2015 Feb 18.

PMID:
25701502
35.

The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway.

Endo Y, Hirahara K, Iinuma T, Shinoda K, Tumes DJ, Asou HK, Matsugae N, Obata-Ninomiya K, Yamamoto H, Motohashi S, Oboki K, Nakae S, Saito H, Okamoto Y, Nakayama T.

Immunity. 2015 Feb 17;42(2):294-308. doi: 10.1016/j.immuni.2015.01.016.

36.

Unique expression features of cancer-type organic anion transporting polypeptide 1B3 mRNA expression in human colon and lung cancers.

Sun Y, Furihata T, Ishii S, Nagai M, Harada M, Shimozato O, Kamijo T, Motohashi S, Yoshino I, Kamiichi A, Kobayashi K, Chiba K.

Clin Transl Med. 2014 Nov 18;3:37. doi: 10.1186/s40169-014-0037-y. eCollection 2014.

37.

Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells.

Frigault MJ, Lee J, Basil MC, Carpenito C, Motohashi S, Scholler J, Kawalekar OU, Guedan S, McGettigan SE, Posey AD Jr, Ang S, Cooper LJ, Platt JM, Johnson FB, Paulos CM, Zhao Y, Kalos M, Milone MC, June CH.

Cancer Immunol Res. 2015 Apr;3(4):356-67. doi: 10.1158/2326-6066.CIR-14-0186. Epub 2015 Jan 19.

38.

Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.

Watanabe Y, Onodera A, Kanai U, Ichikawa T, Obata-Ninomiya K, Wada T, Kiuchi M, Iwamura C, Tumes DJ, Shinoda K, Yagi R, Motohashi S, Hirahara K, Nakayama T.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12829-34. doi: 10.1073/pnas.1321245111. Epub 2014 Aug 18.

39.

Protein tyrosine phosphatase-PEST (PTP-PEST) regulates mast cell-activating signals in PTP activity-dependent and -independent manners.

Motohashi S, Koizumi K, Honda R, Maruyama A, Palmer HE, Mashima K.

Cell Immunol. 2014 May-Jun;289(1-2):128-34. doi: 10.1016/j.cellimm.2014.04.003. Epub 2014 Apr 13.

PMID:
24791697
40.

NKT cells as an ideal anti-tumor immunotherapeutic.

Fujii S, Shimizu K, Okamoto Y, Kunii N, Nakayama T, Motohashi S, Taniguchi M.

Front Immunol. 2013 Dec 2;4:409. doi: 10.3389/fimmu.2013.00409. Review.

41.

The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells.

Tumes DJ, Onodera A, Suzuki A, Shinoda K, Endo Y, Iwamura C, Hosokawa H, Koseki H, Tokoyoda K, Suzuki Y, Motohashi S, Nakayama T.

Immunity. 2013 Nov 14;39(5):819-32. doi: 10.1016/j.immuni.2013.09.012.

42.

Production of Anti-platelet Factor 4/Heparin Complex Antibodies After Cardiovascular Surgery.

Matsuo T, Motohashi S, Wanaka K, Walenga JM.

Clin Appl Thromb Hemost. 2015 Mar;21(2):177-80. doi: 10.1177/1076029613507334. Epub 2013 Nov 6.

PMID:
24203352
43.

Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.

Hosokawa H, Tanaka T, Kato M, Shinoda K, Tohyama H, Hanazawa A, Tamaki Y, Hirahara K, Yagi R, Sakikawa I, Morita A, Nagira M, Poyurovsky MV, Suzuki Y, Motohashi S, Nakayama T.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18626-31. doi: 10.1073/pnas.1311100110. Epub 2013 Oct 28.

44.

Surgical techniques for implanting implantable cardioverter defibrillators in children and infants.

Suzuki S, Motohashi S, Matsumoto M.

Surg Today. 2014 Oct;44(10):1801-6. doi: 10.1007/s00595-013-0755-6. Epub 2013 Oct 24. Review.

PMID:
24154922
45.

[III. Immunotherapy for lung cancer].

Motohashi S.

Gan To Kagaku Ryoho. 2013 Aug;40(8):1015-7. Japanese. No abstract available.

PMID:
24151658
46.

Glycosidic inhibitors of melanogenesis from leaves of Passiflora edulis.

Zhang J, Koike R, Yamamoto A, Ukiya M, Fukatsu M, Banno N, Miura M, Motohashi S, Tokuda H, Akihisa T.

Chem Biodivers. 2013 Oct;10(10):1851-65. doi: 10.1002/cbdv.201300181.

PMID:
24130028
47.

A successful treatment for concomitant injury of the coronary artery and tricuspid valve after blunt chest trauma.

Kikuchi C, Motohashi S, Takahashi Y, Nakazawa S, Kanazawa H.

Gen Thorac Cardiovasc Surg. 2015 Nov;63(11):616-9. doi: 10.1007/s11748-013-0322-5. Epub 2013 Sep 17.

PMID:
24043608
48.

Hybrid procedures for an infant with hypoplastic left heart syndrome with intact atrial septum.

Suzuki S, Kise H, Kaga S, Hoshiai M, Koizumi K, Hasebe Y, Motohashi S, Matsumoto M.

Gen Thorac Cardiovasc Surg. 2015 Aug;63(8):472-5. doi: 10.1007/s11748-013-0304-7. Epub 2013 Aug 3.

PMID:
23907363
49.

A new reverse worm-like micellar system from a lecithin, multivalent carboxylic acid and oil mixture.

Imai M, Hashizaki K, Taguchi H, Saito Y, Motohashi S.

J Colloid Interface Sci. 2013 Aug 1;403:77-83. doi: 10.1016/j.jcis.2013.04.033. Epub 2013 Apr 30.

PMID:
23684226
50.

Recurrent refractory arterial thromboembolism in a patient with anti-phospholipid antibody syndrome.

Sakakibara K, Matsumoto M, Motohashi S, Suzuki S.

Intern Med. 2013;52(10):1145-6. Epub 2013 May 15. No abstract available.

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