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Items: 24


STIM1 activation of adenylyl cyclase 6 connects Ca2+ and cAMP signaling during melanogenesis.

Motiani RK, Tanwar J, Raja DA, Vashisht A, Khanna S, Sharma S, Srivastava S, Sivasubbu S, Natarajan VT, Gokhale RS.

EMBO J. 2018 Mar 1;37(5). pii: e97597. doi: 10.15252/embj.201797597. Epub 2018 Jan 8.


Cardiovascular and Hemostatic Disorders: Role of STIM and Orai Proteins in Vascular Disorders.

Tanwar J, Trebak M, Motiani RK.

Adv Exp Med Biol. 2017;993:425-452. doi: 10.1007/978-3-319-57732-6_22. Review.


Role of SOCE architects STIM and Orai proteins in Cell Death.

Tanwar J, Motiani RK.

Cell Calcium. 2018 Jan;69:19-27. doi: 10.1016/j.ceca.2017.06.002. Epub 2017 Jun 9. Review.


Mitochondria control store-operated Ca2+ entry through Na+ and redox signals.

Ben-Kasus Nissim T, Zhang X, Elazar A, Roy S, Stolwijk JA, Zhou Y, Motiani RK, Gueguinou M, Hempel N, Hershfinkel M, Gill DL, Trebak M, Sekler I.

EMBO J. 2017 Mar 15;36(6):797-815. doi: 10.15252/embj.201592481. Epub 2017 Feb 20.


Water Buffalo (Bubalus bubalis) as a spontaneous animal model of Vitiligo.

Singh VP, Motiani RK, Singh A, Malik G, Aggarwal R, Pratap K, Wani MR, Gokhale SB, Natarajan VT, Gokhale RS.

Pigment Cell Melanoma Res. 2016 Jul;29(4):465-9. doi: 10.1111/pcmr.12485.


STIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis.

Vashisht A, Trebak M, Motiani RK.

Am J Physiol Cell Physiol. 2015 Oct 1;309(7):C457-69. doi: 10.1152/ajpcell.00064.2015. Epub 2015 May 27. Review.


Synthesis, Structure-Activity Relationship, and Mechanistic Investigation of Lithocholic Acid Amphiphiles for Colon Cancer Therapy.

Singh M, Bansal S, Kundu S, Bhargava P, Singh A, Motiani RK, Shyam R, Sreekanth V, Sengupta S, Bajaj A.

Medchemcomm. 2015 Jan;6(1):192-201. doi: 10.1039/C4MD00223G. Epub 2014 Oct 15.


Injectable small molecule hydrogel as a potential nanocarrier for localized and sustained in vivo delivery of doxorubicin.

Singh M, Kundu S, Reddy M A, Sreekanth V, Motiani RK, Sengupta S, Srivastava A, Bajaj A.

Nanoscale. 2014 Nov 7;6(21):12849-55. doi: 10.1039/c4nr04064c.


Design, synthesis, and mechanistic investigations of bile acid-tamoxifen conjugates for breast cancer therapy.

Sreekanth V, Bansal S, Motiani RK, Kundu S, Muppu SK, Majumdar TD, Panjamurthy K, Sengupta S, Bajaj A.

Bioconjug Chem. 2013 Sep 18;24(9):1468-84. doi: 10.1021/bc300664k. Epub 2013 Aug 21.


Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels.

Zhang X, González-Cobos JC, Schindl R, Muik M, Ruhle B, Motiani RK, Bisaillon JM, Zhang W, Fahrner M, Barroso M, Matrougui K, Romanin C, Trebak M.

Mol Cell Biol. 2013 Sep;33(18):3715-23. doi: 10.1128/MCB.00554-13. Epub 2013 Jul 22.


Emerging roles of Orai3 in pathophysiology.

Motiani RK, Stolwijk JA, Newton RL, Zhang X, Trebak M.

Channels (Austin). 2013 Sep-Oct;7(5):392-401. doi: 10.4161/chan.24960. Epub 2013 May 21. Review.


STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion.

Motiani RK, Hyzinski-García MC, Zhang X, Henkel MM, Abdullaev IF, Kuo YH, Matrougui K, Mongin AA, Trebak M.

Pflugers Arch. 2013 Sep;465(9):1249-60. doi: 10.1007/s00424-013-1254-8. Epub 2013 Mar 21.


STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry.

Shinde AV, Motiani RK, Zhang X, Abdullaev IF, Adam AP, González-Cobos JC, Zhang W, Matrougui K, Vincent PA, Trebak M.

Sci Signal. 2013 Mar 19;6(267):ra18. doi: 10.1126/scisignal.2003425.


miR-424/322 regulates vascular smooth muscle cell phenotype and neointimal formation in the rat.

Merlet E, Atassi F, Motiani RK, Mougenot N, Jacquet A, Nadaud S, Capiod T, Trebak M, Lompré AM, Marchand A.

Cardiovasc Res. 2013 Jun 1;98(3):458-68. doi: 10.1093/cvr/cvt045. Epub 2013 Feb 26.


Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia.

González-Cobos JC, Zhang X, Zhang W, Ruhle B, Motiani RK, Schindl R, Muik M, Spinelli AM, Bisaillon JM, Shinde AV, Fahrner M, Singer HA, Matrougui K, Barroso M, Romanin C, Trebak M.

Circ Res. 2013 Mar 29;112(7):1013-25. doi: 10.1161/CIRCRESAHA.111.300220. Epub 2013 Jan 24.


What role for store-operated Ca²⁺ entry in muscle?

Trebak M, Zhang W, Ruhle B, Henkel MM, González-Cobos JC, Motiani RK, Stolwijk JA, Newton RL, Zhang X.

Microcirculation. 2013 May;20(4):330-6. doi: 10.1111/micc.12042. Review.


Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration.

Spinelli AM, González-Cobos JC, Zhang X, Motiani RK, Rowan S, Zhang W, Garrett J, Vincent PA, Matrougui K, Singer HA, Trebak M.

Pflugers Arch. 2012 Nov;464(5):481-92. doi: 10.1007/s00424-012-1160-5. Epub 2012 Sep 27.


Orai3 is an estrogen receptor α-regulated Ca²⁺ channel that promotes tumorigenesis.

Motiani RK, Zhang X, Harmon KE, Keller RS, Matrougui K, Bennett JA, Trebak M.

FASEB J. 2013 Jan;27(1):63-75. doi: 10.1096/fj.12-213801. Epub 2012 Sep 19.


Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury.

Zhang W, Halligan KE, Zhang X, Bisaillon JM, Gonzalez-Cobos JC, Motiani RK, Hu G, Vincent PA, Zhou J, Barroso M, Singer HA, Matrougui K, Trebak M.

Circ Res. 2011 Aug 19;109(5):534-42. doi: 10.1161/CIRCRESAHA.111.246777. Epub 2011 Jul 7.


Essential role for STIM1/Orai1-mediated calcium influx in PDGF-induced smooth muscle migration.

Bisaillon JM, Motiani RK, Gonzalez-Cobos JC, Potier M, Halligan KE, Alzawahra WF, Barroso M, Singer HA, Jourd'heuil D, Trebak M.

Am J Physiol Cell Physiol. 2010 May;298(5):C993-1005. doi: 10.1152/ajpcell.00325.2009. Epub 2010 Jan 27.


Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration.

Potier M, Gonzalez JC, Motiani RK, Abdullaev IF, Bisaillon JM, Singer HA, Trebak M.

FASEB J. 2009 Aug;23(8):2425-37. doi: 10.1096/fj.09-131128. Epub 2009 Apr 13.


Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2.

Zayed N, Afif H, Chabane N, Mfuna-Endam L, Benderdour M, Martel-Pelletier J, Pelletier JP, Motiani RK, Trebak M, Duval N, Fahmi H.

Arthritis Rheum. 2008 Nov;58(11):3530-40. doi: 10.1002/art.23958.


Stim1 and Orai1 mediate CRAC currents and store-operated calcium entry important for endothelial cell proliferation.

Abdullaev IF, Bisaillon JM, Potier M, Gonzalez JC, Motiani RK, Trebak M.

Circ Res. 2008 Nov 21;103(11):1289-99. doi: 10.1161/01.RES.0000338496.95579.56. Epub 2008 Oct 9.

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