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Progress on the regulation of myofibrillar function: Part 2.

Granzier HL, Moss RL.

J Gen Physiol. 2019 May 6;151(5):609. doi: 10.1085/jgp.201912380. Epub 2019 Apr 15. No abstract available.


The enduring relationship between myosin enzymatic activity and the speed of muscle contraction.

Moss RL, Solaro RJ.

J Gen Physiol. 2019 May 6;151(5):623-627. doi: 10.1085/jgp.201912323. Epub 2019 Mar 19. Review. No abstract available.


Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium.

Gregorich ZR, Patel JR, Cai W, Lin Z, Heurer R, Fitzsimons DP, Moss RL, Ge Y.

J Gen Physiol. 2019 May 6;151(5):670-679. doi: 10.1085/jgp.201812214. Epub 2019 Jan 14.


Toward an understanding of the regulation of myofibrillar function.

Moss RL, de Tombe PP, Solaro RJ.

J Gen Physiol. 2019 Jan 7;151(1):1-2. doi: 10.1085/jgp.201812288. Epub 2018 Dec 21. No abstract available.


Recovery of left ventricular function following in vivo reexpression of cardiac myosin binding protein C.

Giles J, Patel JR, Miller A, Iverson E, Fitzsimons D, Moss RL.

J Gen Physiol. 2019 Jan 7;151(1):77-89. doi: 10.1085/jgp.201812238. Epub 2018 Dec 20.


New anthropometric classification scheme of preoperative nutritional status in children: a retrospective observational cohort study.

Stey A, Ricks-Oddie J, Innis S, Rangel SJ, Moss RL, Hall BL, Dibbins A, Skarsgard ED.

BMJ Paediatr Open. 2018 Oct 12;2(1):e000303. doi: 10.1136/bmjpo-2018-000303. eCollection 2018.


Novel Regulatory Elements within Myofilaments of Vertebrate Striated Muscles-Who Knew.

Moss RL.

Biophys J. 2018 Oct 16;115(8):1401-1402. doi: 10.1016/j.bpj.2018.07.043. Epub 2018 Sep 4. No abstract available.


Patient blood management and the importance of the Transfusion Practitioner role to embed this into practice.

Bielby L, Moss RL.

Transfus Med. 2018 Apr;28(2):98-106. doi: 10.1111/tme.12526. Epub 2018 Apr 16. Review.


Hospital variation in rates of concurrent fundoplication during gastrostomy enteral access procedures.

Stey AM, Vinocur CD, Moss RL, Hall BL, Cohen ME, Kraemer K, Ko CY, Kenney BD, Berman L.

Surg Endosc. 2018 May;32(5):2201-2211. doi: 10.1007/s00464-017-5518-9. Epub 2018 Feb 5.


Organ-level right ventricular dysfunction with preserved Frank-Starling mechanism in a mouse model of pulmonary arterial hypertension.

Wang Z, Patel JR, Schreier DA, Hacker TA, Moss RL, Chesler NC.

J Appl Physiol (1985). 2018 May 1;124(5):1244-1253. doi: 10.1152/japplphysiol.00725.2017. Epub 2018 Jan 25.


Altered Right Ventricular Mechanical Properties Are Afterload Dependent in a Rodent Model of Bronchopulmonary Dysplasia.

Patel JR, Barton GP, Braun RK, Goss KN, Haraldsdottir K, Hopp A, Diffee G, Hacker TA, Moss RL, Eldridge MW.

Front Physiol. 2017 Oct 25;8:840. doi: 10.3389/fphys.2017.00840. eCollection 2017.


Single visit surgery for pediatric ambulatory surgical procedures: a satisfaction and cost analysis.

Olson JK, Deming LA, King DR, Rager TM, Gartner S, Huibregtse N, Moss RL, Besner GE.

J Pediatr Surg. 2017 Oct 10. pii: S0022-3468(17)30643-7. doi: 10.1016/j.jpedsurg.2017.10.021. [Epub ahead of print]


Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications (PTMs) in Skeletal Muscles Identified by Top-down Proteomics.

Wei L, Gregorich ZR, Lin Z, Cai W, Jin Y, McKiernan SH, McIlwain S, Aiken JM, Moss RL, Diffee GM, Ge Y.

Mol Cell Proteomics. 2018 Jan;17(1):134-145. doi: 10.1074/mcp.RA117.000124. Epub 2017 Oct 18.


Complete Characterization of Cardiac Myosin Heavy Chain (223 kDa) Enabled by Size-Exclusion Chromatography and Middle-Down Mass Spectrometry.

Jin Y, Wei L, Cai W, Lin Z, Wu Z, Peng Y, Kohmoto T, Moss RL, Ge Y.

Anal Chem. 2017 May 2;89(9):4922-4930. doi: 10.1021/acs.analchem.7b00113. Epub 2017 Apr 12.


Acting on an impulse (or two): Advantages of high-frequency tetanic onset in skeletal muscle.

Moss RL, Lynch TL 4th, Fitzsimons DP.

J Gen Physiol. 2017 Mar 6;149(3):297-300. doi: 10.1085/jgp.201711763. Epub 2017 Feb 17. No abstract available.


Phosphorylation of cardiac myosin binding protein C releases myosin heads from the surface of cardiac thick filaments.

Kensler RW, Craig R, Moss RL.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1355-E1364. doi: 10.1073/pnas.1614020114. Epub 2017 Feb 6.


Acylcarnitine Profiles Reflect Metabolic Vulnerability for Necrotizing Enterocolitis in Newborns Born Premature.

Sylvester KG, Kastenberg ZJ, Moss RL, Enns GM, Cowan TM, Shaw GM, Stevenson DK, Sinclair TJ, Scharfe C, Ryckman KK, Jelliffe-Pawlowski LL.

J Pediatr. 2017 Feb;181:80-85.e1. doi: 10.1016/j.jpeds.2016.10.019. Epub 2016 Nov 8.


Top-Down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light-Chain Phosphorylation That Contributes to Sarcopenic Muscle Dysfunction.

Gregorich ZR, Peng Y, Cai W, Jin Y, Wei L, Chen AJ, McKiernan SH, Aiken JM, Moss RL, Diffee GM, Ge Y.

J Proteome Res. 2016 Aug 5;15(8):2706-16. doi: 10.1021/acs.jproteome.6b00244. Epub 2016 Jul 13.


Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase.

Massengill MT, Ashraf HM, Chowdhury RR, Chrzanowski SM, Kar J, Warren SA, Walter GA, Zeng H, Kang BH, Anderson RH, Moss RL, Kasahara H.

Cardiovasc Res. 2016 Jul 1;111(1):34-43. doi: 10.1093/cvr/cvw069. Epub 2016 Mar 29.


Cardiac myosin-binding protein C: A protein once at loose ends finds its regulatory groove.

Moss RL.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3133-5. doi: 10.1073/pnas.1602568113. Epub 2016 Mar 10. No abstract available.


Variation in intraoperative and postoperative red blood cell transfusion in pediatric surgery.

Stey AM, Vinocur CD, Moss RL, Hall BL, Cohen ME, Kraemer K, Ko CY, Kenney BD.

Transfusion. 2016 Mar;56(3):666-72. doi: 10.1111/trf.13479. Epub 2016 Jan 26.


Effectiveness of Patient Choice in Nonoperative vs Surgical Management of Pediatric Uncomplicated Acute Appendicitis.

Minneci PC, Mahida JB, Lodwick DL, Sulkowski JP, Nacion KM, Cooper JN, Ambeba EJ, Moss RL, Deans KJ.

JAMA Surg. 2016 May 1;151(5):408-15. doi: 10.1001/jamasurg.2015.4534.


Improving Quality and Efficiency for Intussusception Management After Successful Enema Reduction.

Raval MV, Minneci PC, Deans KJ, Kurtovic KJ, Dietrich A, Bates DG, Rangel SJ, Moss RL, Kenney BD.

Pediatrics. 2015 Nov;136(5):e1345-52. doi: 10.1542/peds.2014-3122. Epub 2015 Oct 12.


Estimating Adverse Events After Gastrostomy Tube Placement.

Stey AM, Kenney BD, Cohen ME, Moss RL, Hall BL, Berman L, Kraemer K, Ko CY, Vinocur CD.

Acad Pediatr. 2016 Mar;16(2):129-35. doi: 10.1016/j.acap.2015.05.004. Epub 2015 Aug 22.


Impaired Activity of Blood Coagulant Factor XIII in Patients with Necrotizing Enterocolitis.

Tao GZ, Liu B, Zhang R, Liu G, Abdullah F, Harris MC, Brandt ML, Ehrenkranz RA, Bowers C, Martin CR, Moss RL, Sylvester KG.

Sci Rep. 2015 Aug 17;5:13119. doi: 10.1038/srep13119.


Effective top-down LC/MS+ method for assessing actin isoforms as a potential cardiac disease marker.

Chen YC, Ayaz-Guner S, Peng Y, Lane NM, Locher M, Kohmoto T, Larsson L, Moss RL, Ge Y.

Anal Chem. 2015 Aug 18;87(16):8399-8406. doi: 10.1021/acs.analchem.5b01745. Epub 2015 Jul 31.


Reply to a Letter to the Editor.

ACS Children's Surgery Verification Committee, Oldham KT, Fallat M, Barnhart D, Derkay C, Deshpande J, Georgeson K, Hirschl R, Houck C, Mooney D, Moss RL, Sawin R, Tuggle D.

J Pediatr Surg. 2015 Aug;50(8):1434-6. doi: 10.1016/j.jpedsurg.2015.06.003. Epub 2015 Jun 20. No abstract available. Erratum in: J Pediatr Surg. 2015 Dec;50(12):2173.


Strategies from UW-Madison for rescuing biomedical research in the US.

Kimble J, Bement WM, Chang Q, Cox BL, Drinkwater NR, Gourse RL, Hoskins AA, Huttenlocher A, Kreeger PK, Lambert PF, Mailick MR, Miyamoto S, Moss RL, O'Connor-Giles KM, Roopra A, Saha K, Seidel HS.

Elife. 2015 Jun 30;4:e09305. doi: 10.7554/eLife.09305.


A risk calculator predicting postoperative adverse events in neonates undergoing major abdominal or thoracic surgery.

Stey AM, Kenney BD, Moss RL, Hall BL, Berman L, Cohen ME, Kraemer K, Ko CY, Vinocur CD.

J Pediatr Surg. 2015 Jun;50(6):987-91. doi: 10.1016/j.jpedsurg.2015.03.023. Epub 2015 Mar 17.


Urine biomarkers for necrotizing enterocolitis.

Sylvester KG, Moss RL.

Pediatr Surg Int. 2015 May;31(5):421-9. doi: 10.1007/s00383-015-3693-0. Epub 2015 Mar 26. Review.


Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mutation that depresses ryanodine receptor function.

Zhao YT, Valdivia CR, Gurrola GB, Powers PP, Willis BC, Moss RL, Jalife J, Valdivia HH.

Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1669-77. doi: 10.1073/pnas.1419795112. Epub 2015 Mar 16.


Phosphorylation of cardiac Myosin-binding protein-C is a critical mediator of diastolic function.

Rosas PC, Liu Y, Abdalla MI, Thomas CM, Kidwell DT, Dusio GF, Mukhopadhyay D, Kumar R, Baker KM, Mitchell BM, Powers PA, Fitzsimons DP, Patel BG, Warren CM, Solaro RJ, Moss RL, Tong CW.

Circ Heart Fail. 2015 May;8(3):582-94. doi: 10.1161/CIRCHEARTFAILURE.114.001550. Epub 2015 Mar 4.


Phosphoregulation of Cardiac Inotropy via Myosin Binding Protein-C During Increased Pacing Frequency or β1-Adrenergic Stimulation.

Tong CW, Wu X, Liu Y, Rosas PC, Sadayappan S, Hudmon A, Muthuchamy M, Powers PA, Valdivia HH, Moss RL.

Circ Heart Fail. 2015 May;8(3):595-604. doi: 10.1161/CIRCHEARTFAILURE.114.001585. Epub 2015 Mar 4.


Dissecting human skeletal muscle troponin proteoforms by top-down mass spectrometry.

Chen YC, Sumandea MP, Larsson L, Moss RL, Ge Y.

J Muscle Res Cell Motil. 2015 Apr;36(2):169-81. doi: 10.1007/s10974-015-9404-6. Epub 2015 Jan 23.


Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium.

Moss RL, Fitzsimons DP, Ralphe JC.

Circ Res. 2015 Jan 2;116(1):183-92. doi: 10.1161/CIRCRESAHA.116.300561. Review.


Cardiac tissue structure, properties, and performance: a materials science perspective.

Golob M, Moss RL, Chesler NC.

Ann Biomed Eng. 2014 Oct;42(10):2003-13. doi: 10.1007/s10439-014-1071-z. Epub 2014 Aug 1. Review.


Feasibility of a nonoperative management strategy for uncomplicated acute appendicitis in children.

Minneci PC, Sulkowski JP, Nacion KM, Mahida JB, Cooper JN, Moss RL, Deans KJ.

J Am Coll Surg. 2014 Aug;219(2):272-9. doi: 10.1016/j.jamcollsurg.2014.02.031. Epub 2014 Apr 13.


TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy.

Theis JL, Zimmermann MT, Larsen BT, Rybakova IN, Long PA, Evans JM, Middha S, de Andrade M, Moss RL, Wieben ED, Michels VV, Olson TM.

Hum Mol Genet. 2014 Nov 1;23(21):5793-804. doi: 10.1093/hmg/ddu297. Epub 2014 Jun 11.


The importance of extreme weight percentile in postoperative morbidity in children.

Stey AM, Moss RL, Kraemer K, Cohen ME, Ko CY, Lee Hall B.

J Am Coll Surg. 2014 May;218(5):988-96. doi: 10.1016/j.jamcollsurg.2013.12.051. Epub 2014 Feb 15.


A data-driven algorithm integrating clinical and laboratory features for the diagnosis and prognosis of necrotizing enterocolitis.

Ji J, Ling XB, Zhao Y, Hu Z, Zheng X, Xu Z, Wen Q, Kastenberg ZJ, Li P, Abdullah F, Brandt ML, Ehrenkranz RA, Harris MC, Lee TC, Simpson BJ, Bowers C, Moss RL, Sylvester KG.

PLoS One. 2014 Feb 28;9(2):e89860. doi: 10.1371/journal.pone.0089860. eCollection 2014.


Enhancing NSQIP-Pediatric through integration with the Pediatric Health Information System.

Deans KJ, Cooper JN, Rangel SJ, Raval MV, Minneci PC, Moss RL.

J Pediatr Surg. 2014 Jan;49(1):207-12; discussion 212. doi: 10.1016/j.jpedsurg.2013.09.058. Epub 2013 Oct 5.


Urine protein biomarkers for the diagnosis and prognosis of necrotizing enterocolitis in infants.

Sylvester KG, Ling XB, Liu GY, Kastenberg ZJ, Ji J, Hu Z, Wu S, Peng S, Abdullah F, Brandt ML, Ehrenkranz RA, Harris MC, Lee TC, Simpson BJ, Bowers C, Moss RL.

J Pediatr. 2014 Mar;164(3):607-12.e1-7. doi: 10.1016/j.jpeds.2013.10.091. Epub 2014 Jan 14.


Current concepts in the surgical approach to necrotizing enterocolitis.

Raval MV, Moss RL.

Pathophysiology. 2014 Feb;21(1):105-10. doi: 10.1016/j.pathophys.2013.11.017. Epub 2013 Dec 19.


Critical review, with an optimistic outlook, on Boron Neutron Capture Therapy (BNCT).

Moss RL.

Appl Radiat Isot. 2014 Jun;88:2-11. doi: 10.1016/j.apradiso.2013.11.109. Epub 2013 Dec 4. Review.


Glioblastoma, brain metastases and soft tissue sarcoma of extremities: candidate tumors for BNCT.

Wittig A, Moss RL, Sauerwein WA.

Appl Radiat Isot. 2014 Jun;88:46-9. doi: 10.1016/j.apradiso.2013.11.038. Epub 2013 Nov 28.


Multicenter study of pectus excavatum, final report: complications, static/exercise pulmonary function, and anatomic outcomes.

Kelly RE Jr, Mellins RB, Shamberger RC, Mitchell KK, Lawson ML, Oldham KT, Azizkhan RG, Hebra AV, Nuss D, Goretsky MJ, Sharp RJ, Holcomb GW 3rd, Shim WK, Megison SM, Moss RL, Fecteau AH, Colombani PM, Cooper D, Bagley T, Quinn A, Moskowitz AB, Paulson JF.

J Am Coll Surg. 2013 Dec;217(6):1080-9. doi: 10.1016/j.jamcollsurg.2013.06.019.


Assessing quality in pediatric surgery--the limited role of appendectomy as the optimal target.

Raval MV, Deans KJ, Rangel SJ, Minneci PC, Nwomeh BC, Kelleher KJ, Moss RL.

J Pediatr Surg. 2013 Nov;48(11):2313-9. doi: 10.1016/j.jpedsurg.2013.03.057.


A novel urine peptide biomarker-based algorithm for the prognosis of necrotising enterocolitis in human infants.

Sylvester KG, Ling XB, Liu GY, Kastenberg ZJ, Ji J, Hu Z, Peng S, Lau K, Abdullah F, Brandt ML, Ehrenkranz RA, Harris MC, Lee TC, Simpson J, Bowers C, Moss RL.

Gut. 2014 Aug;63(8):1284-92. doi: 10.1136/gutjnl-2013-305130. Epub 2013 Sep 18.


Risk-adjusted hospital outcomes for children's surgery.

Saito JM, Chen LE, Hall BL, Kraemer K, Barnhart DC, Byrd C, Cohen ME, Fei C, Heiss KF, Huffman K, Ko CY, Latus M, Meara JG, Oldham KT, Raval MV, Richards KE, Shah RK, Sutton LC, Vinocur CD, Moss RL.

Pediatrics. 2013 Sep;132(3):e677-88. doi: 10.1542/peds.2013-0867. Epub 2013 Aug 5.


Evidence-based prevention and surgical treatment of necrotizing enterocolitis-a review of randomized controlled trials.

Raval MV, Hall NJ, Pierro A, Moss RL.

Semin Pediatr Surg. 2013 May;22(2):117-21. doi: 10.1053/j.sempedsurg.2013.01.009. Review.


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