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Reconstructing the sediment concentration of a giant submarine gravity flow.

Stevenson CJ, Feldens P, Georgiopoulou A, Schӧnke M, Krastel S, Piper DJW, Lindhorst K, Mosher D.

Nat Commun. 2018 Jul 5;9(1):2616. doi: 10.1038/s41467-018-05042-6.


Myeloid-derived growth factor is a resident endoplasmic reticulum protein.

Bortnov V, Annis DS, Fogerty FJ, Barretto KT, Turton KB, Mosher DF.

J Biol Chem. 2018 Jun 28. pii: jbc.AC118.002052. doi: 10.1074/jbc.AC118.002052. [Epub ahead of print]


Feasibility of Measurement and Adherence to System Performance Measures for Rheumatoid Arthritis in 5 Models of Care.

Barber CEH, Thorne JC, Ahluwalia V, Burt J, Lacaille D, Marshall DA, Hazlewood GS, Mosher D, Denning L, Szamjo I, Chin R, Hamilton S, Benseler S, Twilt M, Shiff NJ, Bykerk V, Homik J, Barnabe C.

J Rheumatol. 2018 Jun 15. pii: jrheum.171284. doi: 10.3899/jrheum.171284. [Epub ahead of print]


Planning for the Rheumatologist Workforce: Factors Associated With Work Hours and Volumes.

Barber CEH, Nasr M, Barnabe C, Badley EM, Lacaille D, Pope J, Cividino A, Yacyshyn E, Baillie C, Mosher D, Thomson JG, Charnock C, Thorne JC, Zummer M, Brophy J, Ruban TN, Ahluwalia V, McDougall R, Marshall DA.

J Clin Rheumatol. 2018 May 25. doi: 10.1097/RHU.0000000000000803. [Epub ahead of print]


Proteomic and Phosphoproteomic Changes Induced by Prolonged Activation of Human Eosinophils with IL-3.

Esnault S, Hebert AS, Jarjour NN, Coon JJ, Mosher DF.

J Proteome Res. 2018 Jun 1;17(6):2102-2111. doi: 10.1021/acs.jproteome.8b00057. Epub 2018 May 4.


A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis.

Schnellmann R, Sack R, Hess D, Annis DS, Mosher DF, Apte SS, Chiquet-Ehrismann R.

Mol Cell Proteomics. 2018 Jul;17(7):1410-1425. doi: 10.1074/mcp.RA118.000676. Epub 2018 Apr 18.


Expression of novel "LOCGEF" isoforms of ARHGEF18 in eosinophils.

Turton KB, Wilkerson EM, Hebert AS, Fogerty FJ, Schira HM, Botros FE, Coon JJ, Mosher DF.

J Leukoc Biol. 2018 Jul;104(1):135-145. doi: 10.1002/JLB.2MA1017-418RR. Epub 2018 Mar 30.


Microtiter assays for quantitation of assembly of plasma and cellular fibronectin.

Tomasini-Johansson BR, Mosher DF.

Methods Cell Biol. 2018;143:157-170. doi: 10.1016/bs.mcb.2017.10.001. Epub 2017 Nov 15.


Adaptation in a Fibronectin Binding Autolysin of Staphylococcus saprophyticus.

Mortimer TD, Annis DS, O'Neill MB, Bohr LL, Smith TM, Poinar HN, Mosher DF, Pepperell CS.

mSphere. 2017 Nov 29;2(6). pii: e00511-17. doi: 10.1128/mSphere.00511-17. eCollection 2017 Nov-Dec.


Proteomics of Eosinophil Activation.

Mosher DF, Wilkerson EM, Turton KB, Hebert AS, Coon JJ.

Front Med (Lausanne). 2017 Sep 29;4:159. doi: 10.3389/fmed.2017.00159. eCollection 2017. Review.


Development of a Canadian Core Clinical Dataset to Support High-quality Care for Canadian Patients with Rheumatoid Arthritis.

Barber CEH, Mosher DP, Ahluwalia V, Zummer M, Marshall DA, Choquette D, Lacaille D, Bombardier C, Lyddiatt A, Chandran V, Khodyakov D, Dao E, Barnabe C; RACCD Working Group.

J Rheumatol. 2017 Dec;44(12):1813-1822. doi: 10.3899/jrheum.170421. Epub 2017 Oct 1.


Mepolizumab Attenuates Airway Eosinophil Numbers, but Not Their Functional Phenotype, in Asthma.

Kelly EA, Esnault S, Liu LY, Evans MD, Johansson MW, Mathur S, Mosher DF, Denlinger LC, Jarjour NN.

Am J Respir Crit Care Med. 2017 Dec 1;196(11):1385-1395. doi: 10.1164/rccm.201611-2234OC.


IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migration.

Johansson MW, Khanna M, Bortnov V, Annis DS, Nguyen CL, Mosher DF.

Clin Exp Allergy. 2017 Oct;47(10):1263-1274. doi: 10.1111/cea.12934. Epub 2017 May 5.


IL-3 up-regulates and activates human eosinophil CD32 and αMβ2 integrin causing degranulation.

Esnault S, Johansson MW, Kelly EA, Koenderman L, Mosher DF, Jarjour NN.

Clin Exp Allergy. 2017 Apr;47(4):488-498. doi: 10.1111/cea.12876. Epub 2017 Jan 23.


Inflammatory aortic aneurysm in a young patient with ankylosing spondylitis.

Miller RJH, Moore R, Kim B, Mosher D, Alvarez N.

J Vasc Surg. 2017 Aug;66(2):600-604. doi: 10.1016/j.jvs.2016.09.044. Epub 2016 Dec 14.


Stand Up and Be Counted: Measuring and Mapping the Rheumatology Workforce in Canada.

Barber CE, Jewett L, Badley EM, Lacaille D, Cividino A, Ahluwalia V, Averns H, Baillie C, Ellsworth J, Pope J, Levy D, Charnock C, McGowan C, Thorne JC, Barnabe C, Zummer M, Lundon K, McDougall RS, Thomson JG, Yacyshyn EA, Mosher D, Brophy J, Ruban TN, Marshall DA.

J Rheumatol. 2017 Feb;44(2):248-257. doi: 10.3899/jrheum.160621. Epub 2016 Dec 1.


Merging Absolute and Relative Quantitative PCR Data to Quantify STAT3 Splice Variant Transcripts.

Turton KB, Esnault S, Delain LP, Mosher DF.

J Vis Exp. 2016 Oct 9;(116). doi: 10.3791/54473.


Commonalities and differences in the implementation of models of care for arthritis: key informant interviews from Canada.

Cott CA, Davis AM, Badley EM, Wong R, Canizares M, Li LC, Jones A, Brooks S, Ahlwalia V, Hawker G, Jaglal S, Landry M, MacKay C, Mosher D.

BMC Health Serv Res. 2016 Aug 19;16(1):415. doi: 10.1186/s12913-016-1634-9.


Fibroblasts and Mesenchymal Stromal/Stem Cells Are Phenotypically Indistinguishable.

Denu RA, Nemcek S, Bloom DD, Goodrich AD, Kim J, Mosher DF, Hematti P.

Acta Haematol. 2016;136(2):85-97. doi: 10.1159/000445096. Epub 2016 May 18.


Dynamic structure of plasma fibronectin.

Maurer LM, Ma W, Mosher DF.

Crit Rev Biochem Mol Biol. 2015 Jul-Aug;51(4):213-27. doi: 10.1080/10409238.2016.1184224. Epub 2016 May 17. Review.


The Peripheral Blood Eosinophil Proteome.

Wilkerson EM, Johansson MW, Hebert AS, Westphall MS, Mathur SK, Jarjour NN, Schwantes EA, Mosher DF, Coon JJ.

J Proteome Res. 2016 May 6;15(5):1524-33. doi: 10.1021/acs.jproteome.6b00006. Epub 2016 Apr 1.


Targeting Fibronectin To Disrupt In Vivo Candida albicans Biofilms.

Nett JE, Cabezas-Olcoz J, Marchillo K, Mosher DF, Andes DR.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):3152-5. doi: 10.1128/AAC.03094-15. Print 2016 May.


Improving Appropriate Access to Care With Central Referral and Triage in Rheumatology.

Hazlewood GS, Barr SG, Lopatina E, Marshall DA, Lupton TL, Fritzler MJ, Mosher DP, Steber WA, Martin L.

Arthritis Care Res (Hoboken). 2016 Oct;68(10):1547-53. doi: 10.1002/acr.22845. Epub 2016 Aug 19.


Development of System-level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada.

Barber CE, Marshall DA, Mosher DP, Akhavan P, Tucker L, Houghton K, Batthish M, Levy DM, Schmeling H, Ellsworth J, Tibollo H, Grant S, Khodyakov D, Lacaille D; Arthritis Alliance of Canada Performance Measurement Development Panel.

J Rheumatol. 2016 Mar;43(3):530-40. doi: 10.3899/jrheum.150839. Epub 2016 Jan 15.


A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture.

Zheng M, Turton KB, Zhu F, Li Y, Grindle KM, Annis DS, Lu L, Drennan AC, Tweardy DJ, Bharadwaj U, Mosher DF, Rui L.

Oncogenesis. 2016 Jan 4;4:e184. doi: 10.1038/oncsis.2015.44.


Development of key performance indicators to evaluate centralized intake for patients with osteoarthritis and rheumatoid arthritis.

Barber CE, Patel JN, Woodhouse L, Smith C, Weiss S, Homik J, LeClercq S, Mosher D, Christiansen T, Howden JS, Wasylak T, Greenwood-Lee J, Emrick A, Suter E, Kathol B, Khodyakov D, Grant S, Campbell-Scherer D, Phillips L, Hendricks J, Marshall DA.

Arthritis Res Ther. 2015 Nov 14;17:322. doi: 10.1186/s13075-015-0843-7. Review.


Host contributions to construction of three device-associated Candida albicans biofilms.

Nett JE, Zarnowski R, Cabezas-Olcoz J, Brooks EG, Bernhardt J, Marchillo K, Mosher DF, Andes DR.

Infect Immun. 2015 Dec;83(12):4630-8. doi: 10.1128/IAI.00931-15. Epub 2015 Sep 14.


The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA.

Shen B, Estevez B, Xu Z, Kreutz B, Karginov A, Bai Y, Qian F, Norifumi U, Mosher D, Du X.

Mol Biol Cell. 2015 Oct 15;26(20):3658-70. doi: 10.1091/mbc.E15-05-0274. Epub 2015 Aug 26.


Periostin and TGF-β-induced protein: Two peas in a pod?

Mosher DF, Johansson MW, Gillis ME, Annis DS.

Crit Rev Biochem Mol Biol. 2015;50(5):427-39. doi: 10.3109/10409238.2015.1069791. Epub 2015 Aug 10. Review.


Absence of Vitamin K-Dependent γ-Carboxylation in Human Periostin Extracted from Fibrotic Lung or Secreted from a Cell Line Engineered to Optimize γ-Carboxylation.

Annis DS, Ma H, Balas DM, Kumfer KT, Sandbo N, Potts GK, Coon JJ, Mosher DF.

PLoS One. 2015 Aug 14;10(8):e0135374. doi: 10.1371/journal.pone.0135374. eCollection 2015.


Evaluation of a Rheumatology Transition Clinic.

Stringer E, Scott R, Mosher D, MacNeill I, Huber AM, Ramsey S, Lang B.

Pediatr Rheumatol Online J. 2015 Jun 11;13:22. doi: 10.1186/s12969-015-0016-x.


Ratios of Four STAT3 Splice Variants in Human Eosinophils and Diffuse Large B Cell Lymphoma Cells.

Turton KB, Annis DS, Rui L, Esnault S, Mosher DF.

PLoS One. 2015 May 18;10(5):e0127243. doi: 10.1371/journal.pone.0127243. eCollection 2015.


Thrombospondin-1 (TSP1) contributes to the development of vascular inflammation by regulating monocytic cell motility in mouse models of abdominal aortic aneurysm.

Liu Z, Morgan S, Ren J, Wang Q, Annis DS, Mosher DF, Zhang J, Sorenson CM, Sheibani N, Liu B.

Circ Res. 2015 Jul 3;117(2):129-41. doi: 10.1161/CIRCRESAHA.117.305262. Epub 2015 May 4. Erratum in: Circ Res. 2015 Aug 14;117(5):e55.


Estimating the Burden of Osteoarthritis to Plan for the Future.

Marshall DA, Vanderby S, Barnabe C, MacDonald KV, Maxwell C, Mosher D, Wasylak T, Lix L, Enns E, Frank C, Noseworthy T.

Arthritis Care Res (Hoboken). 2015 Oct;67(10):1379-86. doi: 10.1002/acr.22612.


On-Off Kinetics of Engagement of FNI Modules of Soluble Fibronectin by β-Strand Addition.

Ma W, Ma H, Mosher DF.

PLoS One. 2015 Apr 28;10(4):e0124941. doi: 10.1371/journal.pone.0124941. eCollection 2015.


2014 Update of the Canadian Rheumatology Association/spondyloarthritis research consortium of Canada treatment recommendations for the management of spondyloarthritis. Part I: principles of the management of spondyloarthritis in Canada.

Rohekar S, Chan J, Tse SM, Haroon N, Chandran V, Bessette L, Mosher D, Flanagan C, Keen KJ, Adams K, Mallinson M, Thorne C, Rahman P, Gladman DD, Inman RD.

J Rheumatol. 2015 Apr;42(4):654-64. doi: 10.3899/jrheum.141000. Epub 2015 Feb 15.


2014 Update of the Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Treatment Recommendations for the Management of Spondyloarthritis. Part II: Specific Management Recommendations.

Rohekar S, Chan J, Tse SM, Haroon N, Chandran V, Bessette L, Mosher D, Flanagan C, Keen KJ, Adams K, Mallinson M, Thorne C, Rahman P, Gladman DD, Inman RD.

J Rheumatol. 2015 Apr;42(4):665-81. doi: 10.3899/jrheum.141001. Epub 2015 Feb 15.


Bivalent ligation of the collagen-binding modules of fibronectin by SFS, a non-anchored bacterial protein of Streptococcus equi.

Ma W, Ma H, Fogerty FJ, Mosher DF.

J Biol Chem. 2015 Feb 20;290(8):4866-76. doi: 10.1074/jbc.M114.612259. Epub 2014 Dec 18.


Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.

Raval KK, Tao R, White BE, De Lange WJ, Koonce CH, Yu J, Kishnani PS, Thomson JA, Mosher DF, Ralphe JC, Kamp TJ.

J Biol Chem. 2015 Jan 30;290(5):3121-36. doi: 10.1074/jbc.M114.628628. Epub 2014 Dec 8.


What Could the Future Hold? Simulating the Demand for Osteoarthritis (oa) Care in Alberta to Plan a Sustainable Oa Care System.

Marshall D, Vanderby S, Carter M, Wasylak T, Mosher DP, Noseworthy T, Maxwell C, MacDonald K, Frank C.

Value Health. 2014 Nov;17(7):A389. doi: 10.1016/j.jval.2014.08.2664. Epub 2014 Oct 26. No abstract available.


Transitioning to employment with a rheumatic disease: the role of independence, overprotection, and social support.

Jetha A, Badley E, Beaton D, Fortin PR, Shiff NJ, Rosenberg AM, Tucker LB, Mosher DP, Gignac MA.

J Rheumatol. 2014 Dec;41(12):2386-94. doi: 10.3899/jrheum.140419. Epub 2014 Oct 1.


Plasma fibronectin supports hemostasis and regulates thrombosis.

Wang Y, Reheman A, Spring CM, Kalantari J, Marshall AH, Wolberg AS, Gross PL, Weitz JI, Rand ML, Mosher DF, Freedman J, Ni H.

J Clin Invest. 2014 Oct;124(10):4281-93. doi: 10.1172/JCI74630. Epub 2014 Sep 2.


Factor XIII and adipocyte biology.

Mosher DF.

Blood. 2014 Aug 21;124(8):1213-4. doi: 10.1182/blood-2014-07-583880. No abstract available.


A framework for patient-centred care coordination.

Mosher D.

Healthc Manage Forum. 2014 Spring;27(1 Suppl):S37-45. English, French.


Borrelia burgdorferi protein BBK32 binds to soluble fibronectin via the N-terminal 70-kDa region, causing fibronectin to undergo conformational extension.

Harris G, Ma W, Maurer LM, Potts JR, Mosher DF.

J Biol Chem. 2014 Aug 8;289(32):22490-9. doi: 10.1074/jbc.M114.578419. Epub 2014 Jun 24.


Clinical and serological features of patients referred through a rheumatology triage system because of positive antinuclear antibodies.

Fitch-Rogalsky C, Steber W, Mahler M, Lupton T, Martin L, Barr SG, Mosher DP, Wick J, Fritzler MJ.

PLoS One. 2014 Apr 4;9(4):e93812. doi: 10.1371/journal.pone.0093812. eCollection 2014.


Semaphorin 7A is expressed on airway eosinophils and upregulated by IL-5 family cytokines.

Esnault S, Kelly EA, Johansson MW, Liu LY, Han ST, Akhtar M, Sandbo N, Mosher DF, Denlinger LC, Mathur SK, Malter JS, Jarjour NN.

Clin Immunol. 2014 Jan;150(1):90-100. doi: 10.1016/j.clim.2013.11.009. Epub 2013 Nov 23.


Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

Beene LC, Wang LW, Hubmacher D, Keene DR, Reinhardt DP, Annis DS, Mosher DF, Mecham RP, Traboulsi EI, Apte SS.

Invest Ophthalmol Vis Sci. 2013 Dec 23;54(13):8337-44. doi: 10.1167/iovs.13-13121.


IL-5 induces suspended eosinophils to undergo unique global reorganization associated with priming.

Han ST, Mosher DF.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):654-64. doi: 10.1165/rcmb.2013-0181OC.


Complex contributions of fibronectin to initiation and maturation of microfibrils.

Sabatier L, Djokic J, Fagotto-Kaufmann C, Chen M, Annis DS, Mosher DF, Reinhardt DP.

Biochem J. 2013 Dec 1;456(2):283-95. doi: 10.1042/BJ20130699.

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