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A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice.

Al-Moyed H, Cepeda AP, Jung S, Moser T, Kügler S, Reisinger E.

EMBO Mol Med. 2018 Dec 3. pii: e9396. doi: 10.15252/emmm.201809396. [Epub ahead of print]


Individual synaptic vesicles mediate stimulated exocytosis from cochlear inner hair cells.

Grabner CP, Moser T.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12811-12816. doi: 10.1073/pnas.1811814115. Epub 2018 Nov 21.


Considerations for imaging thick, low contrast, and beam sensitive samples with liquid cell transmission electron microscopy.

Moser TH, Shokuhfar T, Evans JE.

Micron. 2018 Nov 1;117:8-15. doi: 10.1016/j.micron.2018.10.007. [Epub ahead of print]


Integrating phylogenomics, phylogenetics, morphometrics, relative genome size and ecological niche modelling disentangles the diversification of Eurasian Euphorbia seguieriana s. l. (Euphorbiaceae).

Frajman B, Záveská E, Gamisch A, Moser T; STEPPE Consortium, Schönswetter P.

Mol Phylogenet Evol. 2018 Nov 8. pii: S1055-7903(18)30552-9. doi: 10.1016/j.ympev.2018.10.046. [Epub ahead of print]


Ultrafast optogenetic stimulation of the auditory pathway by targeting-optimized Chronos.

Keppeler D, Merino RM, Lopez de la Morena D, Bali B, Huet AT, Gehrt A, Wrobel C, Subramanian S, Dombrowski T, Wolf F, Rankovic V, Neef A, Moser T.

EMBO J. 2018 Nov 5. pii: e99649. doi: 10.15252/embj.201899649. [Epub ahead of print]


Ca2+ Regulates the Kinetics of Synaptic Vesicle Fusion at the Afferent Inner Hair Cell Synapse.

Huang CH, Moser T.

Front Cell Neurosci. 2018 Oct 17;12:364. doi: 10.3389/fncel.2018.00364. eCollection 2018.


Axial Tubule Junctions Activate Atrial Ca2+ Release Across Species.

Brandenburg S, Pawlowitz J, Fakuade FE, Kownatzki-Danger D, Kohl T, Mitronova GY, Scardigli M, Neef J, Schmidt C, Wiedmann F, Pavone FS, Sacconi L, Kutschka I, Sossalla S, Moser T, Voigt N, Lehnart SE.

Front Physiol. 2018 Oct 8;9:1227. doi: 10.3389/fphys.2018.01227. eCollection 2018.


Toward the Optical Cochlear Implant.

Dombrowski T, Rankovic V, Moser T.

Cold Spring Harb Perspect Med. 2018 Oct 15. pii: a033225. doi: 10.1101/cshperspect.a033225. [Epub ahead of print]


Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance.

Hagiwara A, Kitahara Y, Grabner CP, Vogl C, Abe M, Kitta R, Ohta K, Nakamura K, Sakimura K, Moser T, Nishi A, Ohtsuka T.

J Cell Biol. 2018 Nov 5;217(11):3993-4006. doi: 10.1083/jcb.201704076. Epub 2018 Sep 6.


Psychophysiological modeling: Current state and future directions.

Bach DR, Castegnetti G, Korn CW, Gerster S, Melinscak F, Moser T.

Psychophysiology. 2018 Nov;55(11):e13214. doi: 10.1111/psyp.13209. Epub 2018 Sep 2. Review.


High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis.

Xu X, Tan X, Tampe B, Wilhelmi T, Hulshoff MS, Saito S, Moser T, Kalluri R, Hasenfuss G, Zeisberg EM, Zeisberg M.

Nat Commun. 2018 Aug 29;9(1):3509. doi: 10.1038/s41467-018-05766-5.


Optogenetic stimulation of cochlear neurons activates the auditory pathway and restores auditory-driven behavior in deaf adult gerbils.

Wrobel C, Dieter A, Huet A, Keppeler D, Duque-Afonso CJ, Vogl C, Hoch G, Jeschke M, Moser T.

Sci Transl Med. 2018 Jul 11;10(449). pii: eaao0540. doi: 10.1126/scitranslmed.aao0540.


[Molecular Understanding of Hearing - How Does This Matter to the Hearing Impaired?]

Moser T.

Laryngorhinootologie. 2018 Mar;97(S 01):S214-S230. doi: 10.1055/s-0043-121595. Epub 2018 Mar 22. English, German.


Radiological identification and analysis of soft tissue musculoskeletal calcifications.

Freire V, Moser TP, Lepage-Saucier M.

Insights Imaging. 2018 Jun 7. doi: 10.1007/s13244-018-0619-0. [Epub ahead of print] Review.


The role of electron irradiation history in liquid cell transmission electron microscopy.

Moser TH, Mehta H, Park C, Kelly RT, Shokuhfar T, Evans JE.

Sci Adv. 2018 Apr 20;4(4):eaaq1202. doi: 10.1126/sciadv.aaq1202. eCollection 2018 Apr.


High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics.

Mager T, Lopez de la Morena D, Senn V, Schlotte J, D Errico A, Feldbauer K, Wrobel C, Jung S, Bodensiek K, Rankovic V, Browne L, Huet A, Jüttner J, Wood PG, Letzkus JJ, Moser T, Bamberg E.

Nat Commun. 2018 May 1;9(1):1750. doi: 10.1038/s41467-018-04146-3.


A practical guide for planning pelvic bone percutaneous interventions (biopsy, tumour ablation and cementoplasty).

Oñate Miranda M, Moser TP.

Insights Imaging. 2018 Jun;9(3):275-285. doi: 10.1007/s13244-018-0600-y. Epub 2018 Mar 21. Review.


Propagation-based phase-contrast x-ray tomography of cochlea using a compact synchrotron source.

Töpperwien M, Gradl R, Keppeler D, Vassholz M, Meyer A, Hessler R, Achterhold K, Gleich B, Dierolf M, Pfeiffer F, Moser T, Salditt T.

Sci Rep. 2018 Mar 21;8(1):4922. doi: 10.1038/s41598-018-23144-5.


Correction to: The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.

Tranebjærg L, Strenzke N, Lindholm S, Rendtorff ND, Poulsen H, Khandelia H, Kopec W, Lyngbye TJB, Hamel C, Delettre C, Bocquet B, Bille M, Owen HH, Bek T, Jensen H, Østergaard K, Möller C, Luxon L, Carr L, Wilson L, Rajput K, Sirimanna T, Harrop-Griffiths K, Rahman S, Vona B, Doll J, Haaf T, Bartsch O, Rosewich H, Moser T, Bitner-Glindzicz M.

Hum Genet. 2018 Mar;137(3):279-280. doi: 10.1007/s00439-018-1870-7.


Is the environment in kindergarten associated with the vegetables served and eaten? The BRA Study.

Himberg-Sundet A, Kristiansen AL, Bjelland M, Moser T, Holthe A, Andersen LF, Lien N.

Scand J Public Health. 2018 Feb 1:1403494818756702. doi: 10.1177/1403494818756702. [Epub ahead of print]


Quantitative optical nanophysiology of Ca2+ signaling at inner hair cell active zones.

Neef J, Urban NT, Ohn TL, Frank T, Jean P, Hell SW, Willig KI, Moser T.

Nat Commun. 2018 Jan 18;9(1):290. doi: 10.1038/s41467-017-02612-y.


The synaptic ribbon is critical for sound encoding at high rates and with temporal precision.

Jean P, Lopez de la Morena D, Michanski S, Jaime Tobón LM, Chakrabarti R, Picher MM, Neef J, Jung S, Gültas M, Maxeiner S, Neef A, Wichmann C, Strenzke N, Grabner C, Moser T.

Elife. 2018 Jan 12;7. pii: e29275. doi: 10.7554/eLife.29275.


The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.

Tranebjærg L, Strenzke N, Lindholm S, Rendtorff ND, Poulsen H, Khandelia H, Kopec W, Lyngbye TJB, Hamel C, Delettre C, Bocquet B, Bille M, Owen HH, Bek T, Jensen H, Østergaard K, Möller C, Luxon L, Carr L, Wilson L, Rajput K, Sirimanna T, Harrop-Griffiths K, Rahman S, Vona B, Doll J, Haaf T, Bartsch O, Rosewich H, Moser T, Bitner-Glindzicz M.

Hum Genet. 2018 Feb;137(2):111-127. doi: 10.1007/s00439-017-1862-z. Epub 2018 Jan 5. Erratum in: Hum Genet. 2018 Feb 12;:.


RIM-Binding Protein 2 Promotes a Large Number of CaV1.3 Ca2+-Channels and Contributes to Fast Synaptic Vesicle Replenishment at Hair Cell Active Zones.

Krinner S, Butola T, Jung S, Wichmann C, Moser T.

Front Cell Neurosci. 2017 Nov 2;11:334. doi: 10.3389/fncel.2017.00334. eCollection 2017.


Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.

Richter KN, Revelo NH, Seitz KJ, Helm MS, Sarkar D, Saleeb RS, D'Este E, Eberle J, Wagner E, Vogl C, Lazaro DF, Richter F, Coy-Vergara J, Coceano G, Boyden ES, Duncan RR, Hell SW, Lauterbach MA, Lehnart SE, Moser T, Outeiro TF, Rehling P, Schwappach B, Testa I, Zapiec B, Rizzoli SO.

EMBO J. 2018 Jan 4;37(1):139-159. doi: 10.15252/embj.201695709. Epub 2017 Nov 16.


Piccolo Promotes Vesicle Replenishment at a Fast Central Auditory Synapse.

Butola T, Wichmann C, Moser T.

Front Synaptic Neurosci. 2017 Oct 25;9:14. doi: 10.3389/fnsyn.2017.00014. eCollection 2017.


Phonomyography as a non-invasive continuous monitoring technique for muscle ischemia in an experimental model of acute compartment syndrome.

Martinez AP, Moser TP, Saran N, Paquet M, Hemmerling T, Berry GK.

Injury. 2017 Nov;48(11):2411-2416. doi: 10.1016/j.injury.2017.08.051. Epub 2017 Aug 26.


Single-Stranded DNA Library Preparation Does Not Preferentially Enrich Circulating Tumor DNA.

Moser T, Ulz P, Zhou Q, Perakis S, Geigl JB, Speicher MR, Heitzer E.

Clin Chem. 2017 Oct;63(10):1656-1659. doi: 10.1373/clinchem.2017.277988. Epub 2017 Aug 14. No abstract available.


Risk Factors for Intensive Care Unit Admission in Patients with Autoimmune Encephalitis.

Harutyunyan G, Hauer L, Dünser MW, Moser T, Pikija S, Leitinger M, Novak HF, Aichhorn W, Trinka E, Sellner J.

Front Immunol. 2017 Jul 28;8:835. doi: 10.3389/fimmu.2017.00835. eCollection 2017.


Objectively measured physical activity level and sedentary behavior in Norwegian children during a week in preschool.

Andersen E, Borch-Jenssen J, Øvreås S, Ellingsen H, Jørgensen KA, Moser T.

Prev Med Rep. 2017 Jun 9;7:130-135. doi: 10.1016/j.pmedr.2017.06.003. eCollection 2017 Sep.


Rab Interacting Molecules 2 and 3 Directly Interact with the Pore-Forming CaV1.3 Ca2+ Channel Subunit and Promote Its Membrane Expression.

Picher MM, Oprişoreanu AM, Jung S, Michel K, Schoch S, Moser T.

Front Cell Neurosci. 2017 Jun 8;11:160. doi: 10.3389/fncel.2017.00160. eCollection 2017.


Validation of the ultrasonographic assessment of the femoral trochlea epiphyseal cartilage in foals at osteochondrosis predilected sites with magnetic resonance imaging and histology.

Martel G, Forget C, Gilbert G, Richard H, Moser T, Olive J, Laverty S.

Equine Vet J. 2017 Nov;49(6):821-828. doi: 10.1111/evj.12698. Epub 2017 Jun 19.


Associations between clinical outcome and navigated transcranial magnetic stimulation characteristics in patients with motor-eloquent brain lesions: a combined navigated transcranial magnetic stimulation-diffusion tensor imaging fiber tracking approach.

Sollmann N, Wildschuetz N, Kelm A, Conway N, Moser T, Bulubas L, Kirschke JS, Meyer B, Krieg SM.

J Neurosurg. 2018 Mar;128(3):800-810. doi: 10.3171/2016.11.JNS162322. Epub 2017 Mar 31.


Resection of Navigated Transcranial Magnetic Stimulation-Positive Prerolandic Motor Areas Causes Permanent Impairment of Motor Function.

Moser T, Bulubas L, Sabih J, Conway N, Wildschutz N, Sollmann N, Meyer B, Ringel F, Krieg SM.

Neurosurgery. 2017 Jul 1;81(1):99-110. doi: 10.1093/neuros/nyw169.


Ecotoxicity of boric acid in standard laboratory tests with plants and soil organisms.

Princz J, Becker L, Scheffczyk A, Stephenson G, Scroggins R, Moser T, Römbke J.

Ecotoxicology. 2017 May;26(4):471-481. doi: 10.1007/s10646-017-1789-0. Epub 2017 Mar 17. Review.


Having Fun and Staying Active! Children with Disabilities and Participation in Physical Activity: A Follow-Up Study.

Baksjøberget PE, Nyquist A, Moser T, Jahnsen R.

Phys Occup Ther Pediatr. 2017 Nov;37(4):347-358. doi: 10.1080/01942638.2017.1281369. Epub 2017 Mar 16.


Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells.

Picher MM, Gehrt A, Meese S, Ivanovic A, Predoehl F, Jung S, Schrauwen I, Dragonetti AG, Colombo R, Van Camp G, Strenzke N, Moser T.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1717-E1726. doi: 10.1073/pnas.1617533114. Epub 2017 Feb 9.


Cortical plasticity of motor-eloquent areas measured by navigated transcranial magnetic stimulation in patients with glioma.

Conway N, Wildschuetz N, Moser T, Bulubas L, Sollmann N, Tanigawa N, Meyer B, Krieg SM.

J Neurosurg. 2017 Nov;127(5):981-991. doi: 10.3171/2016.9.JNS161595. Epub 2017 Jan 20.


Conditional deletion of pejvakin in adult outer hair cells causes progressive hearing loss in mice.

Harris SL, Kazmierczak M, Pangršič T, Shah P, Chuchvara N, Barrantes-Freer A, Moser T, Schwander M.

Neuroscience. 2017 Mar 6;344:380-393. doi: 10.1016/j.neuroscience.2016.12.055. Epub 2017 Jan 9.


3D dosimetric validation of motion compensation concepts in radiotherapy using an anthropomorphic dynamic lung phantom.

Mann P, Witte M, Moser T, Lang C, Runz A, Johnen W, Berger M, Biederer J, Karger CP.

Phys Med Biol. 2017 Jan 21;62(2):573-595. doi: 10.1088/1361-6560/aa51b1. Epub 2016 Dec 29.


Autoimmune Encephalitis at the Neurological Intensive Care Unit: Etiologies, Reasons for Admission and Survival.

Harutyunyan G, Hauer L, Dünser MW, Karamyan A, Moser T, Pikija S, Leitinger M, Novak HF, Trinka E, Sellner J.

Neurocrit Care. 2017 Aug;27(1):82-89. doi: 10.1007/s12028-016-0370-7.


Fabrication of electrocatalytic Ta nanoparticles by reactive sputtering and ion soft landing.

Johnson GE, Moser T, Engelhard M, Browning ND, Laskin J.

J Chem Phys. 2016 Nov 7;145(17):174701.


Femoral epiphyseal cartilage matrix changes at predilection sites of equine osteochondrosis: Quantitative MRI, second-harmonic microscopy, and histological findings.

Martel G, Couture CA, Gilbert G, Bancelin S, Richard H, Moser T, Kiss S, Légaré F, Laverty S.

J Orthop Res. 2016 Oct;34(10):1743-1752. doi: 10.1002/jor.23176. Epub 2016 Feb 8.


New insights into cochlear sound encoding.

Moser T, Vogl C.

F1000Res. 2016 Aug 26;5. pii: F1000 Faculty Rev-2081. doi: 10.12688/f1000research.8924.1. eCollection 2016. Review.


Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes.

Ohn TL, Rutherford MA, Jing Z, Jung S, Duque-Afonso CJ, Hoch G, Picher MM, Scharinger A, Strenzke N, Moser T.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4716-25. doi: 10.1073/pnas.1605737113. Epub 2016 Jul 26.


Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.

Vogl C, Panou I, Yamanbaeva G, Wichmann C, Mangosing SJ, Vilardi F, Indzhykulian AA, Pangršič T, Santarelli R, Rodriguez-Ballesteros M, Weber T, Jung S, Cardenas E, Wu X, Wojcik SM, Kwan KY, Del Castillo I, Schwappach B, Strenzke N, Corey DP, Lin SY, Moser T.

EMBO J. 2016 Dec 1;35(23):2536-2552. Epub 2016 Jul 25.


Farmers' Preferences for Future Agricultural Land Use Under the Consideration of Climate Change.

Pröbstl-Haider U, Mostegl NM, Kelemen-Finan J, Haider W, Formayer H, Kantelhardt J, Moser T, Kapfer M, Trenholm R.

Environ Manage. 2016 Sep;58(3):446-64. doi: 10.1007/s00267-016-0720-4. Epub 2016 Jul 2.


Ultrasound-Guided Cervical Facet Joint Injections: A Viable Substitution for Fluoroscopy-Guided Injections?

Freire V, Grabs D, Lepage-Saucier M, Moser TP.

J Ultrasound Med. 2016 Jun;35(6):1253-8. doi: 10.7863/ultra.15.07062. Epub 2016 May 5.


Prediction of Hip Failure Load: In Vitro Study of 80 Femurs Using Three Imaging Methods and Finite Element Models-The European Fracture Study (EFFECT).

Pottecher P, Engelke K, Duchemin L, Museyko O, Moser T, Mitton D, Vicaut E, Adams J, Skalli W, Laredo JD, Bousson V.

Radiology. 2016 Sep;280(3):837-47. doi: 10.1148/radiol.2016142796. Epub 2016 Apr 14.


DNA Diagnostics of Hereditary Hearing Loss: A Targeted Resequencing Approach Combined with a Mutation Classification System.

Sommen M, Schrauwen I, Vandeweyer G, Boeckx N, Corneveaux JJ, van den Ende J, Boudewyns A, De Leenheer E, Janssens S, Claes K, Verstreken M, Strenzke N, Predöhl F, Wuyts W, Mortier G, Bitner-Glindzicz M, Moser T, Coucke P, Huentelman MJ, Van Camp G.

Hum Mutat. 2016 Aug;37(8):812-9. doi: 10.1002/humu.22999. Epub 2016 May 6.


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