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Stable Pom1 clusters form a glucose-modulated concentration gradient that regulates mitotic entry.

Allard CAH, Opalko HE, Moseley JB.

Elife. 2019 May 3;8. pii: e46003. doi: 10.7554/eLife.46003.



Moseley JB.

Curr Biol. 2018 Apr 23;28(8):R376-R378. doi: 10.1016/j.cub.2017.11.073.


Cell size-dependent regulation of Wee1 localization by Cdr2 cortical nodes.

Allard CAH, Opalko HE, Liu KW, Medoh U, Moseley JB.

J Cell Biol. 2018 May 7;217(5):1589-1599. doi: 10.1083/jcb.201709171. Epub 2018 Mar 7.


Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division.

Lee ME, Rusin SF, Jenkins N, Kettenbach AN, Moseley JB.

Curr Biol. 2018 Jan 8;28(1):84-92.e4. doi: 10.1016/j.cub.2017.11.034. Epub 2017 Dec 14.


Dynamic regulation of Cdr1 kinase localization and phosphorylation during osmotic stress.

Opalko HE, Moseley JB.

J Biol Chem. 2017 Nov 10;292(45):18457-18468. doi: 10.1074/jbc.M117.793034. Epub 2017 Sep 18.


Transient activation of fission yeast AMPK is required for cell proliferation during osmotic stress.

Schutt KL, Moseley JB.

Mol Biol Cell. 2017 Jul 1;28(13):1804-1814. doi: 10.1091/mbc.E17-04-0235. Epub 2017 May 17.


Wee1 and Cdc25: Tools, pathways, mechanisms, questions.

Moseley JB.

Cell Cycle. 2017 Apr 3;16(7):599-600. doi: 10.1080/15384101.2017.1302229. No abstract available.


Phosphatases Generate Signal Specificity Downstream of Ssp1 Kinase in Fission Yeast.

Deng L, Lee ME, Schutt KL, Moseley JB.

Mol Cell Biol. 2017 May 2;37(10). pii: e00494-16. doi: 10.1128/MCB.00494-16. Print 2017 May 15.


CAG Expansions Are Genetically Stable and Form Nontoxic Aggregates in Cells Lacking Endogenous Polyglutamine Proteins.

Zurawel AA, Kabeche R, DiGregorio SE, Deng L, Menon KM, Opalko H, Duennwald ML, Moseley JB, Supattapone S.

MBio. 2016 Sep 27;7(5). pii: e01367-16. doi: 10.1128/mBio.01367-16.


Sideline Management of Joint Dislocations.

Schupp CM, Rand SE, Hanson TW, Lee BM, Jafarnia K, Jia Y, Moseley JB, Seaberg JP, Seelhoefer GM.

Curr Sports Med Rep. 2016 May-Jun;15(3):140-53. doi: 10.1249/JSR.0000000000000266.


Pil1 cytoplasmic rods contain bundles of crosslinked tubules.

Kabeche R, Howard L, Moseley JB.

Commun Integr Biol. 2015 Mar 4;8(1):e990848. doi: 10.4161/19420889.2014.990848. eCollection 2015 Jan-Feb.


Eisosomes provide membrane reservoirs for rapid expansion of the yeast plasma membrane.

Kabeche R, Howard L, Moseley JB.

J Cell Sci. 2015 Nov 15;128(22):4057-62. doi: 10.1242/jcs.176867. Epub 2015 Sep 24.


Eisosomes Regulate Phosphatidylinositol 4,5-Bisphosphate (PI(4,5)P2) Cortical Clusters and Mitogen-activated Protein (MAP) Kinase Signaling upon Osmotic Stress.

Kabeche R, Madrid M, Cansado J, Moseley JB.

J Biol Chem. 2015 Oct 23;290(43):25960-73. doi: 10.1074/jbc.M115.674192. Epub 2015 Sep 10.


Cytokinesis: does Mid1 have an identity crisis?

Moseley JB.

Curr Biol. 2015 May 4;25(9):R364-6. doi: 10.1016/j.cub.2015.03.017.


Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.

Kettenbach AN, Deng L, Wu Y, Baldissard S, Adamo ME, Gerber SA, Moseley JB.

Mol Cell Proteomics. 2015 May;14(5):1275-87. doi: 10.1074/mcp.M114.045245. Epub 2015 Feb 26.


Megadalton-node assembly by binding of Skb1 to the membrane anchor Slf1.

Deng L, Kabeche R, Wang N, Wu JQ, Moseley JB.

Mol Biol Cell. 2014 Sep 1;25(17):2660-8. doi: 10.1091/mbc.E14-04-0896. Epub 2014 Jul 9.


Actin cytoskeleton: a nucleator face-off.

Moseley JB.

Curr Biol. 2014 Mar 3;24(5):R194-6. doi: 10.1016/j.cub.2014.01.043.


Dueling kinases regulate cell size at division through the SAD kinase Cdr2.

Deng L, Baldissard S, Kettenbach AN, Gerber SA, Moseley JB.

Curr Biol. 2014 Feb 17;24(4):428-33. doi: 10.1016/j.cub.2014.01.009. Epub 2014 Feb 6.


A Pil1-Sle1-Syj1-Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation.

Kabeche R, Roguev A, Krogan NJ, Moseley JB.

J Cell Sci. 2014 Mar 15;127(Pt 6):1318-26. doi: 10.1242/jcs.143545. Epub 2014 Jan 16.


Cellular aging: symmetry evades senescence.

Moseley JB.

Curr Biol. 2013 Oct 7;23(19):R871-3. doi: 10.1016/j.cub.2013.08.013.


An expanded view of the eukaryotic cytoskeleton.

Moseley JB.

Mol Biol Cell. 2013 Jun;24(11):1615-8. doi: 10.1091/mbc.E12-10-0732.


Compartmentalized nodes control mitotic entry signaling in fission yeast.

Deng L, Moseley JB.

Mol Biol Cell. 2013 Jun;24(12):1872-81. doi: 10.1091/mbc.E13-02-0104. Epub 2013 Apr 24.


Blt1 and Mid1 provide overlapping membrane anchors to position the division plane in fission yeast.

Guzman-Vendrell M, Baldissard S, Almonacid M, Mayeux A, Paoletti A, Moseley JB.

Mol Cell Biol. 2013 Jan;33(2):418-28. doi: 10.1128/MCB.01286-12. Epub 2012 Nov 12.


Seg1 controls eisosome assembly and shape.

Moreira KE, Schuck S, Schrul B, Fröhlich F, Moseley JB, Walther TC, Walter P.

J Cell Biol. 2012 Aug 6;198(3):405-20. doi: 10.1083/jcb.201202097.


The filament-forming protein Pil1 assembles linear eisosomes in fission yeast.

Kabeche R, Baldissard S, Hammond J, Howard L, Moseley JB.

Mol Biol Cell. 2011 Nov;22(21):4059-67. doi: 10.1091/mbc.E11-07-0605. Epub 2011 Sep 7.


Mechanism and cellular function of Bud6 as an actin nucleation-promoting factor.

Graziano BR, DuPage AG, Michelot A, Breitsprecher D, Moseley JB, Sagot I, Blanchoin L, Goode BL.

Mol Biol Cell. 2011 Nov;22(21):4016-28. doi: 10.1091/mbc.E11-05-0404. Epub 2011 Aug 31.


Cell division intersects with cell geometry.

Moseley JB, Nurse P.

Cell. 2010 Jul 23;142(2):184-8. doi: 10.1016/j.cell.2010.07.004.


Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1.

Okada K, Bartolini F, Deaconescu AM, Moseley JB, Dogic Z, Grigorieff N, Gundersen GG, Goode BL.

J Cell Biol. 2010 Jun 28;189(7):1087-96. doi: 10.1083/jcb.201001016. Epub 2010 Jun 21.


Long-term durability of autologous chondrocyte implantation: a multicenter, observational study in US patients.

Moseley JB Jr, Anderson AF, Browne JE, Mandelbaum BR, Micheli LJ, Fu F, Erggelet C.

Am J Sports Med. 2010 Feb;38(2):238-46. doi: 10.1177/0363546509348000.


A spatial gradient coordinates cell size and mitotic entry in fission yeast.

Moseley JB, Mayeux A, Paoletti A, Nurse P.

Nature. 2009 Jun 11;459(7248):857-60. doi: 10.1038/nature08074. Epub 2009 May 27.


Spatial control of cytokinesis by Cdr2 kinase and Mid1/anillin nuclear export.

Almonacid M, Moseley JB, Janvore J, Mayeux A, Fraisier V, Nurse P, Paoletti A.

Curr Biol. 2009 Jun 9;19(11):961-6. doi: 10.1016/j.cub.2009.04.024. Epub 2009 May 7.


Displacement of formins from growing barbed ends by bud14 is critical for actin cable architecture and function.

Chesarone M, Gould CJ, Moseley JB, Goode BL.

Dev Cell. 2009 Feb;16(2):292-302. doi: 10.1016/j.devcel.2008.12.001.


Cdk1 and cell morphology: connections and directions.

Moseley JB, Nurse P.

Curr Opin Cell Biol. 2009 Feb;21(1):82-8. doi: 10.1016/ Epub 2009 Feb 3. Review.


The formin mDia2 stabilizes microtubules independently of its actin nucleation activity.

Bartolini F, Moseley JB, Schmoranzer J, Cassimeris L, Goode BL, Gundersen GG.

J Cell Biol. 2008 May 5;181(3):523-36. doi: 10.1083/jcb.200709029.


Regulation and targeting of the fission yeast formin cdc12p in cytokinesis.

Yonetani A, Lustig RJ, Moseley JB, Takeda T, Goode BL, Chang F.

Mol Biol Cell. 2008 May;19(5):2208-19. doi: 10.1091/mbc.E07-07-0731. Epub 2008 Feb 27.


Treatment outcomes of autologous chondrocyte implantation for full-thickness articular cartilage defects of the trochlea.

Mandelbaum B, Browne JE, Fu F, Micheli LJ, Moseley JB Jr, Erggelet C, Anderson AF.

Am J Sports Med. 2007 Jun;35(6):915-21. Epub 2007 Mar 21.


Regulated binding of adenomatous polyposis coli protein to actin.

Moseley JB, Bartolini F, Okada K, Wen Y, Gundersen GG, Goode BL.

J Biol Chem. 2007 Apr 27;282(17):12661-8. Epub 2007 Feb 8.


The yeast actin cytoskeleton: from cellular function to biochemical mechanism.

Moseley JB, Goode BL.

Microbiol Mol Biol Rev. 2006 Sep;70(3):605-45. Review.


Articular cartilage defects of the distal femur in children and adolescents: treatment with autologous chondrocyte implantation.

Micheli LJ, Moseley JB, Anderson AF, Browne JE, Erggelet C, Arciero R, Fu FH, Mandelbaum BR.

J Pediatr Orthop. 2006 Jul-Aug;26(4):455-60.


Twinfilin is an actin-filament-severing protein and promotes rapid turnover of actin structures in vivo.

Moseley JB, Okada K, Balcer HI, Kovar DR, Pollard TD, Goode BL.

J Cell Sci. 2006 Apr 15;119(Pt 8):1547-57. Epub 2006 Mar 28.


Injury risk in professional basketball players: a comparison of Women's National Basketball Association and National Basketball Association athletes.

Deitch JR, Starkey C, Walters SL, Moseley JB.

Am J Sports Med. 2006 Jul;34(7):1077-83. Epub 2006 Feb 21.


Formin proteins: purification and measurement of effects on actin assembly.

Moseley JB, Maiti S, Goode BL.

Methods Enzymol. 2006;406:215-34.


Autologous chondrocyte implantation versus debridement for treatment of full-thickness chondral defects of the knee: an observational cohort study with 3-year follow-up.

Fu FH, Zurakowski D, Browne JE, Mandelbaum B, Erggelet C, Moseley JB Jr, Anderson AF, Micheli LJ.

Am J Sports Med. 2005 Nov;33(11):1658-66. Epub 2005 Aug 10.


Clinical outcome of autologous chondrocyte implantation at 5 years in US subjects.

Browne JE, Anderson AF, Arciero R, Mandelbaum B, Moseley JB Jr, Micheli LJ, Fu F, Erggelet C.

Clin Orthop Relat Res. 2005 Jul;(436):237-45.


Differential activities and regulation of Saccharomyces cerevisiae formin proteins Bni1 and Bnr1 by Bud6.

Moseley JB, Goode BL.

J Biol Chem. 2005 Jul 29;280(30):28023-33. Epub 2005 May 27.


A high-affinity interaction with ADP-actin monomers underlies the mechanism and in vivo function of Srv2/cyclase-associated protein.

Mattila PK, Quintero-Monzon O, Kugler J, Moseley JB, Almo SC, Lappalainen P, Goode BL.

Mol Biol Cell. 2004 Nov;15(11):5158-71. Epub 2004 Sep 8.


Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture.

Xu Y, Moseley JB, Sagot I, Poy F, Pellman D, Goode BL, Eck MJ.

Cell. 2004 Mar 5;116(5):711-23.


A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin.

Moseley JB, Sagot I, Manning AL, Xu Y, Eck MJ, Pellman D, Goode BL.

Mol Biol Cell. 2004 Feb;15(2):896-907. Epub 2003 Dec 2.


Joint-specific multidimensional assessment of pain (J-MAP): factor structure, reliability, validity, and responsiveness in patients with knee osteoarthritis.

O'Malley KJ, Suarez-Almazor M, Aniol J, Richardson P, Kuykendall DH, Moseley JB Jr, Wray NP.

J Rheumatol. 2003 Mar;30(3):534-43.


Arthroscopic treatment of osteoarthritis of the knee.

Wray NP, Moseley JB, O'Malley K.

J Bone Joint Surg Am. 2003 Feb;85(2):381. No abstract available.


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