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Items: 11


Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.

Moscovitz JE, Kalgutkar AS, Nulick K, Johnson N, Lin Z, Goosen TC, Weng Y.

J Pharmacol Exp Ther. 2018 May;365(2):262-271. doi: 10.1124/jpet.117.247296. Epub 2018 Feb 12.


Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas.

Bircsak KM, Moscovitz JE, Wen X, Archer F, Yuen PYS, Mohammed M, Memon N, Weinberger BI, Saba LM, Vetrano AM, Aleksunes LM.

Drug Metab Dispos. 2018 May;46(5):619-627. doi: 10.1124/dmd.117.079228. Epub 2018 Jan 31.


Diabetes area patent participation analysis - part II: years 2011-2016.

Boehm M, Crawford M, Moscovitz JE, Carpino PA.

Expert Opin Ther Pat. 2018 Feb;28(2):111-122. doi: 10.1080/13543776.2018.1406477. Epub 2017 Nov 29. Review.


Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor.

Moscovitz JE, Lin Z, Johnson N, Tu M, Goosen TC, Weng Y, Kalgutkar AS.

Xenobiotica. 2018 Jul;48(7):647-655. doi: 10.1080/00498254.2017.1353163. Epub 2017 Jul 24.


Differential regulation of intestinal efflux transporters by pregnancy in mice.

Moscovitz JE, Yarmush G, Herrera-Garcia G, Guo GL, Aleksunes LM.

Xenobiotica. 2017 Nov;47(11):989-997. doi: 10.1080/00498254.2016.1250292. Epub 2017 Jan 3.


Regulation of Drug Disposition Gene Expression in Pregnant Mice with Car Receptor Activation.

Bright AS, Herrera-Garcia G, Moscovitz JE, You D, Guo GL, Aleksunes LM.

Nucl Receptor Res. 2016;3. pii: 101193.


Restoration of enterohepatic bile acid pathways in pregnant mice following short term activation of Fxr by GW4064.

Moscovitz JE, Kong B, Buckley K, Buckley B, Guo GL, Aleksunes LM.

Toxicol Appl Pharmacol. 2016 Nov 1;310:60-67. doi: 10.1016/j.taap.2016.08.021. Epub 2016 Sep 5.


Correlation between Conjugated Bisphenol A Concentrations and Efflux Transporter Expression in Human Fetal Livers.

Moscovitz JE, Nahar MS, Shalat SL, Slitt AL, Dolinoy DC, Aleksunes LM.

Drug Metab Dispos. 2016 Jul;44(7):1061-5. doi: 10.1124/dmd.115.068668. Epub 2016 Feb 5.


Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice.

Rudraiah S, Moscovitz JE, Donepudi AC, Campion SN, Slitt AL, Aleksunes LM, Manautou JE.

Toxicology. 2014 Nov 5;325:85-95. doi: 10.1016/j.tox.2014.08.013. Epub 2014 Sep 2.


Establishment of metabolism and transport pathways in the rodent and human fetal liver.

Moscovitz JE, Aleksunes LM.

Int J Mol Sci. 2013 Dec 6;14(12):23801-27. doi: 10.3390/ijms141223801. Review.


Keap1-knockdown decreases fasting-induced fatty liver via altered lipid metabolism and decreased fatty acid mobilization from adipose tissue.

Xu J, Donepudi AC, Moscovitz JE, Slitt AL.

PLoS One. 2013 Nov 4;8(11):e79841. doi: 10.1371/journal.pone.0079841. eCollection 2013.

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