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Items: 1 to 50 of 165

1.

Sleep oscillation-specific associations with Alzheimer's disease CSF biomarkers: novel roles for sleep spindles and tau.

Kam K, Parekh A, Sharma RA, Andrade A, Lewin M, Castillo B, Bubu OM, Chua NJ, Miller MD, Mullins AE, Glodzik L, Mosconi L, Gosselin N, Prathamesh K, Chen Z, Blennow K, Zetterberg H, Bagchi N, Cavedoni B, Rapoport DM, Ayappa I, de Leon MJ, Petkova E, Varga AW, Osorio RS.

Mol Neurodegener. 2019 Feb 21;14(1):10. doi: 10.1186/s13024-019-0309-5.

2.

Using social media to disseminate education about Alzheimer's prevention & treatment: a pilot study on Alzheimer's universe (www.AlzU.org).

Isaacson RS, Seifan A, Haddox CL, Mureb M, Rahman A, Scheyer O, Hackett K, Caesar E, Chen JL, Isaacson J, McInnis M, Mosconi L, Safdieh J.

J Commun Healthc. 2018;11(2):106-113. doi: 10.1080/17538068.2018.1467068. Epub 2018 May 5.

3.

Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging study.

Mosconi L, Rahman A, Diaz I, Wu X, Scheyer O, Hristov HW, Vallabhajosula S, Isaacson RS, de Leon MJ, Brinton RD.

PLoS One. 2018 Dec 12;13(12):e0207885. doi: 10.1371/journal.pone.0207885. eCollection 2018.

4.

Utility of the NIH Toolbox for assessment of prodromal Alzheimer's disease and dementia.

Hackett K, Krikorian R, Giovannetti T, Melendez-Cabrero J, Rahman A, Caesar EE, Chen JL, Hristov H, Seifan A, Mosconi L, Isaacson RS.

Alzheimers Dement (Amst). 2018 Nov 2;10:764-772. doi: 10.1016/j.dadm.2018.10.002. eCollection 2018.

5.

Associations of lifestyle and vascular risk factors with Alzheimer's brain biomarker changes during middle age: a 3-year longitudinal study in the broader New York City area.

Walters MJ, Sterling J, Quinn C, Ganzer C, Osorio RS, Andrews RD, Matthews DC, Vallabhajosula S, de Leon MJ, Isaacson RS, Mosconi L.

BMJ Open. 2018 Nov 25;8(11):e023664. doi: 10.1136/bmjopen-2018-023664.

6.

The clinical practice of risk reduction for Alzheimer's disease: A precision medicine approach.

Isaacson RS, Ganzer CA, Hristov H, Hackett K, Caesar E, Cohen R, Kachko R, Meléndez-Cabrero J, Rahman A, Scheyer O, Hwang MJ, Berkowitz C, Hendrix S, Mureb M, Schelke MW, Mosconi L, Seifan A, Krikorian R.

Alzheimers Dement. 2018 Dec;14(12):1663-1673. doi: 10.1016/j.jalz.2018.08.004. Epub 2018 Nov 13.

7.

Clinical Application of APOE in Alzheimer's Prevention: A Precision Medicine Approach.

Berkowitz CL, Mosconi L, Rahman A, Scheyer O, Hristov H, Isaacson RS.

J Prev Alzheimers Dis. 2018;5(4):245-252. doi: 10.14283/jpad.2018.35.

8.

Female Sex and Alzheimer's Risk: The Menopause Connection.

Scheyer O, Rahman A, Hristov H, Berkowitz C, Isaacson RS, Diaz Brinton R, Mosconi L.

J Prev Alzheimers Dis. 2018;5(4):225-230. doi: 10.14283/jpad.2018.34.

9.

How would we combat menopause as an Alzheimer's risk factor?

Mosconi L, Brinton RD.

Expert Rev Neurother. 2018 Sep;18(9):689-691. doi: 10.1080/14737175.2018.1510320. Epub 2018 Aug 13. No abstract available.

10.

Precision Medicine for Alzheimer's Disease Prevention.

Berkowitz CL, Mosconi L, Scheyer O, Rahman A, Hristov H, Isaacson RS.

Healthcare (Basel). 2018 Jul 13;6(3). pii: E82. doi: 10.3390/healthcare6030082. Review.

11.

Mechanisms of Risk Reduction in the Clinical Practice of Alzheimer's Disease Prevention.

Schelke MW, Attia P, Palenchar DJ, Kaplan B, Mureb M, Ganzer CA, Scheyer O, Rahman A, Kachko R, Krikorian R, Mosconi L, Isaacson RS.

Front Aging Neurosci. 2018 Apr 10;10:96. doi: 10.3389/fnagi.2018.00096. eCollection 2018. Review.

12.

Mediterranean diet and 3-year Alzheimer brain biomarker changes in middle-aged adults.

Berti V, Walters M, Sterling J, Quinn CG, Logue M, Andrews R, Matthews DC, Osorio RS, Pupi A, Vallabhajosula S, Isaacson RS, de Leon MJ, Mosconi L.

Neurology. 2018 May 15;90(20):e1789-e1798. doi: 10.1212/WNL.0000000000005527. Epub 2018 Apr 13.

13.

Lifestyle and vascular risk effects on MRI-based biomarkers of Alzheimer's disease: a cross-sectional study of middle-aged adults from the broader New York City area.

Mosconi L, Walters M, Sterling J, Quinn C, McHugh P, Andrews RE, Matthews DC, Ganzer C, Osorio RS, Isaacson RS, De Leon MJ, Convit A.

BMJ Open. 2018 Mar 23;8(3):e019362. doi: 10.1136/bmjopen-2017-019362.

14.

Correction: Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery.

Mosconi L, Berti V, Quinn C, McHugh P, Petrongolo G, Osorio RS, Connaughty C, Pupi A, Vallabhajosula S, Isaacson RS, de Leon MJ, Swerdlow RH, Diaz Brinton R.

PLoS One. 2018 Feb 15;13(2):e0193314. doi: 10.1371/journal.pone.0193314. eCollection 2018.

15.

Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly. A Longitudinal Study.

Sharma RA, Varga AW, Bubu OM, Pirraglia E, Kam K, Parekh A, Wohlleber M, Miller MD, Andrade A, Lewis C, Tweardy S, Buj M, Yau PL, Sadda R, Mosconi L, Li Y, Butler T, Glodzik L, Fieremans E, Babb JS, Blennow K, Zetterberg H, Lu SE, Badia SG, Romero S, Rosenzweig I, Gosselin N, Jean-Louis G, Rapoport DM, de Leon MJ, Ayappa I, Osorio RS.

Am J Respir Crit Care Med. 2018 Apr 1;197(7):933-943. doi: 10.1164/rccm.201704-0704OC.

16.

Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery.

Mosconi L, Berti V, Quinn C, McHugh P, Petrongolo G, Osorio RS, Connaughty C, Pupi A, Vallabhajosula S, Isaacson RS, de Leon MJ, Swerdlow RH, Brinton RD.

PLoS One. 2017 Oct 10;12(10):e0185926. doi: 10.1371/journal.pone.0185926. eCollection 2017. Erratum in: PLoS One. 2018 Feb 15;13(2):e0193314.

17.

Sex differences in Alzheimer risk: Brain imaging of endocrine vs chronologic aging.

Mosconi L, Berti V, Quinn C, McHugh P, Petrongolo G, Varsavsky I, Osorio RS, Pupi A, Vallabhajosula S, Isaacson RS, de Leon MJ, Brinton RD.

Neurology. 2017 Sep 26;89(13):1382-1390. doi: 10.1212/WNL.0000000000004425. Epub 2017 Aug 30.

18.

Dissociation of Down syndrome and Alzheimer's disease effects with imaging.

Matthews DC, Lukic AS, Andrews RD, Marendic B, Brewer J, Rissman RA, Mosconi L, Strother SC, Wernick MN, Mobley WC, Ness S, Schmidt ME, Rafii MS.

Alzheimers Dement (N Y). 2016 Jun;2(2):69-81. doi: 10.1016/j.trci.2016.02.004.

19.

Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Aβ42 Levels in Cognitively Normal Elderly.

Varga AW, Wohlleber ME, Giménez S, Romero S, Alonso JF, Ducca EL, Kam K, Lewis C, Tanzi EB, Tweardy S, Kishi A, Parekh A, Fischer E, Gumb T, Alcolea D, Fortea J, Lleó A, Blennow K, Zetterberg H, Mosconi L, Glodzik L, Pirraglia E, Burschtin OE, de Leon MJ, Rapoport DM, Lu SE, Ayappa I, Osorio RS.

Sleep. 2016 Nov 1;39(11):2041-2048.

20.

Transient and chronic seizure-induced inflammation in human focal epilepsy.

Butler T, Li Y, Tsui W, Friedman D, Maoz A, Wang X, Harvey P, Tanzi E, Morim S, Kang Y, Mosconi L, Talos D, Kuzniecky R, Vallhabjosula S, Thesen T, Glodzik L, Ichise M, Silbersweig D, Stern E, de Leon MJ, French J.

Epilepsia. 2016 Sep;57(9):e191-4. doi: 10.1111/epi.13457. Epub 2016 Jul 6.

21.

Effects of vascular risk factors, statins, and antihypertensive drugs on PiB deposition in cognitively normal subjects.

Glodzik L, Rusinek H, Kamer A, Pirraglia E, Tsui W, Mosconi L, Li Y, McHugh P, Murray J, Williams S, Osorio RS, Randall C, Butler T, Deshpande A, Vallabhajolusa S, de Leon M.

Alzheimers Dement (Amst). 2016 Apr 19;2:95-104. doi: 10.1016/j.dadm.2016.02.007. eCollection 2016.

22.

Orexin-A is Associated with Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects.

Osorio RS, Ducca EL, Wohlleber ME, Tanzi EB, Gumb T, Twumasi A, Tweardy S, Lewis C, Fischer E, Koushyk V, Cuartero-Toledo M, Sheikh MO, Pirraglia E, Zetterberg H, Blennow K, Lu SE, Mosconi L, Glodzik L, Schuetz S, Varga AW, Ayappa I, Rapoport DM, de Leon MJ.

Sleep. 2016 Jun 1;39(6):1253-60. doi: 10.5665/sleep.5846.

23.
24.

Sleep-disordered breathing advances cognitive decline in the elderly.

Osorio RS, Gumb T, Pirraglia E, Varga AW, Lu SE, Lim J, Wohlleber ME, Ducca EL, Koushyk V, Glodzik L, Mosconi L, Ayappa I, Rapoport DM, de Leon MJ; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2015 May 12;84(19):1964-71. doi: 10.1212/WNL.0000000000001566. Epub 2015 Apr 15.

25.

Nutrient patterns and brain biomarkers of Alzheimer's disease in cognitively normal individuals.

Berti V, Murray J, Davies M, Spector N, Tsui WH, Li Y, Williams S, Pirraglia E, Vallabhajosula S, McHugh P, Pupi A, de Leon MJ, Mosconi L.

J Nutr Health Aging. 2015 Apr;19(4):413-23. doi: 10.1007/s12603-014-0534-0.

26.

Physical Activity, Mediterranean Diet and Biomarkers-Assessed Risk of Alzheimer's: A Multi-Modality Brain Imaging Study.

Matthews DC, Davies M, Murray J, Williams S, Tsui WH, Li Y, Andrews RD, Lukic A, McHugh P, Vallabhajosula S, de Leon MJ, Mosconi L.

Adv J Mol Imaging. 2014 Oct;4(4):43-57.

27.

Cortical laminar binding of PET amyloid and tau tracers in Alzheimer disease.

Li Y, Tsui W, Rusinek H, Butler T, Mosconi L, Pirraglia E, Mozley D, Vallabhajosula S, Harada R, Furumoto S, Furukawa K, Arai H, Kudo Y, Okamura N, de Leon MJ.

J Nucl Med. 2015 Feb;56(2):270-3. doi: 10.2967/jnumed.114.149229. Epub 2015 Jan 8.

28.

FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease.

Murray J, Tsui WH, Li Y, McHugh P, Williams S, Cummings M, Pirraglia E, Solnes L, Osorio R, Glodzik L, Vallabhajosula S, Drzezga A, Minoshima S, de Leon MJ, Mosconi L.

Adv J Mol Imaging. 2014 Apr;4(2):15-26.

29.

Periodontal disease associates with higher brain amyloid load in normal elderly.

Kamer AR, Pirraglia E, Tsui W, Rusinek H, Vallabhajosula S, Mosconi L, Yi L, McHugh P, Craig RG, Svetcov S, Linker R, Shi C, Glodzik L, Williams S, Corby P, Saxena D, de Leon MJ.

Neurobiol Aging. 2015 Feb;36(2):627-33. doi: 10.1016/j.neurobiolaging.2014.10.038. Epub 2014 Nov 5.

30.

Reduced retention of Pittsburgh compound B in white matter lesions.

Glodzik L, Rusinek H, Li J, Zhou C, Tsui W, Mosconi L, Li Y, Osorio R, Williams S, Randall C, Spector N, McHugh P, Murray J, Pirraglia E, Vallabhajolusa S, de Leon M.

Eur J Nucl Med Mol Imaging. 2015 Jan;42(1):97-102. doi: 10.1007/s00259-014-2897-1. Epub 2014 Oct 21.

31.

Mediterranean Diet and Magnetic Resonance Imaging-Assessed Brain Atrophy in Cognitively Normal Individuals at Risk for Alzheimer's Disease.

Mosconi L, Murray J, Tsui WH, Li Y, Davies M, Williams S, Pirraglia E, Spector N, Osorio RS, Glodzik L, McHugh P, de Leon MJ.

J Prev Alzheimers Dis. 2014 Jun;1(1):23-32.

32.

Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter.

Glodzik L, Kuceyeski A, Rusinek H, Tsui W, Mosconi L, Li Y, Osorio RS, Williams S, Randall C, Spector N, McHugh P, Murray J, Pirraglia E, Vallabhajosula S, Raj A, de Leon MJ.

Neuroimage. 2014 Oct 15;100:684-691. doi: 10.1016/j.neuroimage.2014.06.060. Epub 2014 Jul 4.

33.

Nutrient intake and brain biomarkers of Alzheimer's disease in at-risk cognitively normal individuals: a cross-sectional neuroimaging pilot study.

Mosconi L, Murray J, Davies M, Williams S, Pirraglia E, Spector N, Tsui WH, Li Y, Butler T, Osorio RS, Glodzik L, Vallabhajosula S, McHugh P, Marmar CR, de Leon MJ.

BMJ Open. 2014 Jun 24;4(6):e004850. doi: 10.1136/bmjopen-2014-004850.

34.

A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease.

Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, van der Flier WM, Glodzik L, van Harten AC, de Leon MJ, McHugh P, Mielke MM, Molinuevo JL, Mosconi L, Osorio RS, Perrotin A, Petersen RC, Rabin LA, Rami L, Reisberg B, Rentz DM, Sachdev PS, de la Sayette V, Saykin AJ, Scheltens P, Shulman MB, Slavin MJ, Sperling RA, Stewart R, Uspenskaya O, Vellas B, Visser PJ, Wagner M; Subjective Cognitive Decline Initiative (SCD-I) Working Group.

Alzheimers Dement. 2014 Nov;10(6):844-52. doi: 10.1016/j.jalz.2014.01.001. Epub 2014 May 3. Review.

35.
36.

Brain imaging of cognitively normal individuals with 2 parents affected by late-onset AD.

Mosconi L, Murray J, Tsui WH, Li Y, Spector N, Goldowsky A, Williams S, Osorio R, McHugh P, Glodzik L, Vallabhajosula S, de Leon MJ.

Neurology. 2014 Mar 4;82(9):752-60. doi: 10.1212/WNL.0000000000000181. Epub 2014 Feb 12.

37.

Interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals.

Osorio RS, Ayappa I, Mantua J, Gumb T, Varga A, Mooney AM, Burschtin OE, Taxin Z, During E, Spector N, Biagioni M, Pirraglia E, Lau H, Zetterberg H, Blennow K, Lu SE, Mosconi L, Glodzik L, Rapoport DM, de Leon MJ.

Neurobiol Aging. 2014 Jun;35(6):1318-24. doi: 10.1016/j.neurobiolaging.2013.12.030. Epub 2013 Dec 27.

38.
39.

Imaging and cerebrospinal fluid biomarkers in the search for Alzheimer's disease mechanisms.

Osorio RS, Pirraglia E, Gumb T, Mantua J, Ayappa I, Williams S, Mosconi L, Glodzik L, de Leon MJ.

Neurodegener Dis. 2014;13(2-3):163-5. doi: 10.1159/000355063. Epub 2013 Oct 2.

40.

Blood pressure decrease correlates with tau pathology and memory decline in hypertensive elderly.

Glodzik L, Rusinek H, Pirraglia E, McHugh P, Tsui W, Williams S, Cummings M, Li Y, Rich K, Randall C, Mosconi L, Osorio R, Murray J, Zetterberg H, Blennow K, de Leon M.

Neurobiol Aging. 2014 Jan;35(1):64-71. doi: 10.1016/j.neurobiolaging.2013.06.011. Epub 2013 Aug 19.

41.

Cerebrospinal fluid biomarkers of Alzheimer's disease in healthy elderly.

Randall C, Mosconi L, de Leon M, Glodzik L.

Front Biosci (Landmark Ed). 2013 Jun 1;18:1150-73. Review.

42.

Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease.

Protas HD, Chen K, Langbaum JB, Fleisher AS, Alexander GE, Lee W, Bandy D, de Leon MJ, Mosconi L, Buckley S, Truran-Sacrey D, Schuff N, Weiner MW, Caselli RJ, Reiman EM.

JAMA Neurol. 2013 Mar 1;70(3):320-5.

43.

Comparing brain amyloid deposition, glucose metabolism, and atrophy in mild cognitive impairment with and without a family history of dementia.

Mosconi L, Andrews RD, Matthews DC.

J Alzheimers Dis. 2013;35(3):509-24. doi: 10.3233/JAD-121867.

PMID:
23478305
44.

Alternative normalization methods demonstrate widespread cortical hypometabolism in untreated de novo Parkinson's disease.

Berti V, Polito C, Borghammer P, Ramat S, Mosconi L, Vanzi E, De Cristofaro MT, De Leon M, Sorbi S, Pupi A.

Q J Nucl Med Mol Imaging. 2012 Jun;56(3):299-308.

45.

Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents.

Mosconi L, Rinne JO, Tsui WH, Murray J, Li Y, Glodzik L, McHugh P, Williams S, Cummings M, Pirraglia E, Goldsmith SJ, Vallabhajosula S, Scheinin N, Viljanen T, Någren K, de Leon MJ.

Neurobiol Aging. 2013 Jan;34(1):22-34. doi: 10.1016/j.neurobiolaging.2012.03.002. Epub 2012 Apr 11.

46.

Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimer's disease.

Mosconi L, de Leon M, Murray J, E L, Lu J, Javier E, McHugh P, Swerdlow RH.

J Alzheimers Dis. 2011;27(3):483-90. doi: 10.3233/JAD-2011-110866.

47.

PET/CT in diagnosis of movement disorders.

Berti V, Pupi A, Mosconi L.

Ann N Y Acad Sci. 2011 Jun;1228:93-108. doi: 10.1111/j.1749-6632.2011.06025.x. Review.

48.

PET/CT in diagnosis of dementia.

Berti V, Pupi A, Mosconi L.

Ann N Y Acad Sci. 2011 Jun;1228:81-92. doi: 10.1111/j.1749-6632.2011.06015.x. Review.

49.

Rat liver mitochondrial proteome: changes associated with aging and acetyl-L-carnitine treatment.

Musicco C, Capelli V, Pesce V, Timperio AM, Calvani M, Mosconi L, Cantatore P, Gadaleta MN.

J Proteomics. 2011 Oct 19;74(11):2536-47. doi: 10.1016/j.jprot.2011.05.041. Epub 2011 Jun 6.

PMID:
21672642
50.

The concept of FDG-PET endophenotype in Alzheimer's disease.

During EH, Osorio RS, Elahi FM, Mosconi L, de Leon MJ.

Neurol Sci. 2011 Aug;32(4):559-69. doi: 10.1007/s10072-011-0633-1. Epub 2011 Jun 1. Review.

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