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Items: 26


Layer-by-layer nanoparticles for novel delivery of cisplatin and PARP inhibitors for platinum-based drug resistance therapy in ovarian cancer.

Mensah LB, Morton SW, Li J, Xiao H, Quadir MA, Elias KM, Penn E, Richson AK, Ghoroghchian PP, Liu J, Hammond PT.

Bioeng Transl Med. 2019 Jun 14;4(2):e10131. doi: 10.1002/btm2.10131. eCollection 2019 May.


Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles.

Lam FC, Morton SW, Wyckoff J, Vu Han TL, Hwang MK, Maffa A, Balkanska-Sinclair E, Yaffe MB, Floyd SR, Hammond PT.

Nat Commun. 2018 May 18;9(1):1991. doi: 10.1038/s41467-018-04315-4.


Quantitative Comparison of Enzyme Immobilization Strategies for Glucose Biosensing in Real-Time Using Fast-Scan Cyclic Voltammetry Coupled with Carbon-Fiber Microelectrodes.

Smith SK, Lugo-Morales LZ, Tang C, Gosrani SP, Lee CA, Roberts JG, Morton SW, McCarty GS, Khan SA, Sombers LA.

Chemphyschem. 2018 May 22;19(10):1197-1204. doi: 10.1002/cphc.201701235. Epub 2018 Feb 5.


Ligand-decorated click polypeptide derived nanoparticles for targeted drug delivery applications.

Quadir MA, Morton SW, Mensah LB, Shopsowitz K, Dobbelaar J, Effenberger N, Hammond PT.

Nanomedicine. 2017 Jul;13(5):1797-1808. doi: 10.1016/j.nano.2017.02.010. Epub 2017 Mar 2.


Tumor-Targeted Synergistic Blockade of MAPK and PI3K from a Layer-by-Layer Nanoparticle.

Dreaden EC, Kong YW, Morton SW, Correa S, Choi KY, Shopsowitz KE, Renggli K, Drapkin R, Yaffe MB, Hammond PT.

Clin Cancer Res. 2015 Oct 1;21(19):4410-9. doi: 10.1158/1078-0432.CCR-15-0013. Epub 2015 Jun 1.


A plug-and-play ratiometric pH-sensing nanoprobe for high-throughput investigation of endosomal escape.

Deng ZJ, Morton SW, Bonner DK, Gu L, Ow H, Hammond PT.

Biomaterials. 2015 May;51:250-256. doi: 10.1016/j.biomaterials.2015.02.013. Epub 2015 Feb 20.


Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging.

Sowers MA, McCombs JR, Wang Y, Paletta JT, Morton SW, Dreaden EC, Boska MD, Ottaviani MF, Hammond PT, Rajca A, Johnson JA.

Nat Commun. 2014 Nov 18;5:5460. doi: 10.1038/ncomms6460.


Layer-by-layer assembled antisense DNA microsponge particles for efficient delivery of cancer therapeutics.

Roh YH, Lee JB, Shopsowitz KE, Dreaden EC, Morton SW, Poon Z, Hong J, Yamin I, Bonner DK, Hammond PT.

ACS Nano. 2014 Oct 28;8(10):9767-80. doi: 10.1021/nn502596b. Epub 2014 Oct 14.


Bimodal tumor-targeting from microenvironment responsive hyaluronan layer-by-layer (LbL) nanoparticles.

Dreaden EC, Morton SW, Shopsowitz KE, Choi JH, Deng ZJ, Cho NJ, Hammond PT.

ACS Nano. 2014 Aug 26;8(8):8374-82. doi: 10.1021/nn502861t. Epub 2014 Aug 11.


Cross-linked polymer nanofibers for hyperthermophilic enzyme immobilization: approaches to improve enzyme performance.

Tang C, Saquing CD, Morton SW, Glatz BN, Kelly RM, Khan SA.

ACS Appl Mater Interfaces. 2014 Aug 13;6(15):11899-906. doi: 10.1021/am5033633. Epub 2014 Aug 1.


RNAi-microsponges form through self-assembly of the organic and inorganic products of transcription.

Shopsowitz KE, Roh YH, Deng ZJ, Morton SW, Hammond PT.

Small. 2014 Apr 24;10(8):1623-33.


A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways.

Morton SW, Lee MJ, Deng ZJ, Dreaden EC, Siouve E, Shopsowitz KE, Shah NJ, Yaffe MB, Hammond PT.

Sci Signal. 2014 May 13;7(325):ra44. doi: 10.1126/scisignal.2005261.


PEG-polypeptide block copolymers as pH-responsive endosome-solubilizing drug nanocarriers.

Quadir MA, Morton SW, Deng ZJ, Shopsowitz KE, Murphy RP, Epps TH 3rd, Hammond PT.

Mol Pharm. 2014 Jul 7;11(7):2420-30. doi: 10.1021/mp500162w. Epub 2014 Jun 12.


A convergent synthetic platform for single-nanoparticle combination cancer therapy: ratiometric loading and controlled release of cisplatin, doxorubicin, and camptothecin.

Liao L, Liu J, Dreaden EC, Morton SW, Shopsowitz KE, Hammond PT, Johnson JA.

J Am Chem Soc. 2014 Apr 23;136(16):5896-9. doi: 10.1021/ja502011g. Epub 2014 Apr 11.


FRET-enabled biological characterization of polymeric micelles.

Morton SW, Zhao X, Quadir MA, Hammond PT.

Biomaterials. 2014 Apr;35(11):3489-96. doi: 10.1016/j.biomaterials.2014.01.027. Epub 2014 Jan 26.


Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment.

Deng ZJ, Morton SW, Ben-Akiva E, Dreaden EC, Shopsowitz KE, Hammond PT.

ACS Nano. 2013 Nov 26;7(11):9571-84. doi: 10.1021/nn4047925. Epub 2013 Oct 21.


Osteotropic therapy via targeted layer-by-layer nanoparticles.

Morton SW, Shah NJ, Quadir MA, Deng ZJ, Poon Z, Hammond PT.

Adv Healthc Mater. 2014 Jun;3(6):867-75. doi: 10.1002/adhm.201300465. Epub 2013 Oct 9.


Inhibition of vein graft stenosis with a c-jun targeting DNAzyme in a cationic liposomal formulation containing 1,2-dioleoyl-3-trimethylammonium propane (DOTAP)/1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE).

Li Y, Bhindi R, Deng ZJ, Morton SW, Hammond PT, Khachigian LM.

Int J Cardiol. 2013 Oct 9;168(4):3659-64. doi: 10.1016/j.ijcard.2013.05.092. Epub 2013 Jul 22.


Scalable manufacture of built-to-order nanomedicine: spray-assisted layer-by-layer functionalization of PRINT nanoparticles.

Morton SW, Herlihy KP, Shopsowitz KE, Deng ZJ, Chu KS, Bowerman CJ, Desimone JM, Hammond PT.

Adv Mater. 2013 Sep 14;25(34):4707-13. doi: 10.1002/adma.201302025. Epub 2013 Jul 1.


Surface-mediated bone tissue morphogenesis from tunable nanolayered implant coatings.

Shah NJ, Hyder MN, Moskowitz JS, Quadir MA, Morton SW, Seeherman HJ, Padera RF, Spector M, Hammond PT.

Sci Transl Med. 2013 Jun 26;5(191):191ra83. doi: 10.1126/scitranslmed.3005576.


Fluorescent multiblock π-conjugated polymer nanoparticles for in vivo tumor targeting.

Ahmed E, Morton SW, Hammond PT, Swager TM.

Adv Mater. 2013 Aug 27;25(32):4504-10. doi: 10.1002/adma.201301656. Epub 2013 Jun 24.


Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER).

Cho EA, Moloney FJ, Cai H, Au-Yeung A, China C, Scolyer RA, Yosufi B, Raftery MJ, Deng JZ, Morton SW, Hammond PT, Arkenau HT, Damian DL, Francis DJ, Chesterman CN, Barnetson RS, Halliday GM, Khachigian LM.

Lancet. 2013 May 25;381(9880):1835-43. doi: 10.1016/S0140-6736(12)62166-7. Epub 2013 May 7.


The architecture and biological performance of drug-loaded LbL nanoparticles.

Morton SW, Poon Z, Hammond PT.

Biomaterials. 2013 Jul;34(21):5328-35. doi: 10.1016/j.biomaterials.2013.03.059. Epub 2013 Apr 22.


Controlling in vivo stability and biodistribution in electrostatically assembled nanoparticles for systemic delivery.

Poon Z, Lee JB, Morton SW, Hammond PT.

Nano Lett. 2011 May 11;11(5):2096-103. doi: 10.1021/nl200636r. Epub 2011 Apr 27.


Voltammetric detection of hydrogen peroxide at carbon fiber microelectrodes.

Sanford AL, Morton SW, Whitehouse KL, Oara HM, Lugo-Morales LZ, Roberts JG, Sombers LA.

Anal Chem. 2010 Jun 15;82(12):5205-10. doi: 10.1021/ac100536s.


Prenatal diagnosis of heterozygosity for biotinidase deficiency by enzymatic and molecular analyses.

Pomponio RJ, Hymes J, Pandya A, Landa B, Melone P, Javaheri R, Mardach R, Morton SW, Meyers GA, Reynolds T, Buck G, Nance WE, Wolf B.

Prenat Diagn. 1998 Feb;18(2):117-22.


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