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Items: 1 to 50 of 144

1.

Deletion of a specific exon in the voltage-gated calcium channel, cacophony, causes disrupted locomotion in Drosophila larvae.

Lembke KM, Law AD, Ahrar J, Morton DB.

J Exp Biol. 2018 Nov 5. pii: jeb.191106. doi: 10.1242/jeb.191106. [Epub ahead of print]

PMID:
30397173
2.

Exploring the Interaction of Drosophila TDP-43 and the Type II Voltage-Gated Calcium Channel, Cacophony, in Regulating Motor Function and Behavior.

Lembke KM, Morton DB.

J Exp Neurosci. 2017 Nov 15;11:1179069517740892. doi: 10.1177/1179069517740892. eCollection 2017.

3.

Challenges facing the veterinary profession in Ireland: 2. On-farm use of veterinary antimicrobials.

Magalhães-Sant'Ana M, More SJ, Morton DB, Hanlon AJ.

Ir Vet J. 2017 Sep 15;70:28. doi: 10.1186/s13620-017-0106-9. eCollection 2017.

4.

Restoration of Motor Defects Caused by Loss of Drosophila TDP-43 by Expression of the Voltage-Gated Calcium Channel, Cacophony, in Central Neurons.

Lembke KM, Scudder C, Morton DB.

J Neurosci. 2017 Sep 27;37(39):9486-9497. doi: 10.1523/JNEUROSCI.0554-17.2017. Epub 2017 Aug 28.

5.

Challenges facing the veterinary profession in Ireland: 3. emergency and casualty slaughter certification.

Magalhães-Sant'Ana M, More SJ, Morton DB, Hanlon AJ.

Ir Vet J. 2017 Aug 4;70:24. doi: 10.1186/s13620-017-0102-0. eCollection 2017.

7.

Challenges facing the veterinary profession in Ireland: 1. clinical veterinary services.

Magalhães-Sant'Ana M, More SJ, Morton DB, Hanlon AJ.

Ir Vet J. 2017 Jun 5;70:17. doi: 10.1186/s13620-017-0096-7. eCollection 2017.

8.

Ethical challenges facing veterinary professionals in Ireland: results from Policy Delphi with vignette methodology.

Magalhães-Sant'Ana M, More SJ, Morton DB, Hanlon A.

Vet Rec. 2016 Oct 29;179(17):437. doi: 10.1136/vr.103786. Epub 2016 Sep 9.

9.

Animal suffering and expert evidence.

Morton DB.

Vet Rec. 2016 Sep 24;179(12):305-6. doi: 10.1136/vr.i4970. No abstract available.

PMID:
27660355
10.

Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta.

Kanost MR, Arrese EL, Cao X, Chen YR, Chellapilla S, Goldsmith MR, Grosse-Wilde E, Heckel DG, Herndon N, Jiang H, Papanicolaou A, Qu J, Soulages JL, Vogel H, Walters J, Waterhouse RM, Ahn SJ, Almeida FC, An C, Aqrawi P, Bretschneider A, Bryant WB, Bucks S, Chao H, Chevignon G, Christen JM, Clarke DF, Dittmer NT, Ferguson LCF, Garavelou S, Gordon KHJ, Gunaratna RT, Han Y, Hauser F, He Y, Heidel-Fischer H, Hirsh A, Hu Y, Jiang H, Kalra D, Klinner C, König C, Kovar C, Kroll AR, Kuwar SS, Lee SL, Lehman R, Li K, Li Z, Liang H, Lovelace S, Lu Z, Mansfield JH, McCulloch KJ, Mathew T, Morton B, Muzny DM, Neunemann D, Ongeri F, Pauchet Y, Pu LL, Pyrousis I, Rao XJ, Redding A, Roesel C, Sanchez-Gracia A, Schaack S, Shukla A, Tetreau G, Wang Y, Xiong GH, Traut W, Walsh TK, Worley KC, Wu D, Wu W, Wu YQ, Zhang X, Zou Z, Zucker H, Briscoe AD, Burmester T, Clem RJ, Feyereisen R, Grimmelikhuijzen CJP, Hamodrakas SJ, Hansson BS, Huguet E, Jermiin LS, Lan Q, Lehman HK, Lorenzen M, Merzendorfer H, Michalopoulos I, Morton DB, Muthukrishnan S, Oakeshott JG, Palmer W, Park Y, Passarelli AL, Rozas J, Schwartz LM, Smith W, Southgate A, Vilcinskas A, Vogt R, Wang P, Werren J, Yu XQ, Zhou JJ, Brown SJ, Scherer SE, Richards S, Blissard GW.

Insect Biochem Mol Biol. 2016 Sep;76:118-147. doi: 10.1016/j.ibmb.2016.07.005. Epub 2016 Aug 12.

11.

The upper limits of pain and suffering in animal research.

Beauchamp TL, Morton DB.

Camb Q Healthc Ethics. 2015 Oct;24(4):431-47. doi: 10.1017/S0963180115000092.

PMID:
26364778
12.

Role for Rab10 in Methamphetamine-Induced Behavior.

Vanderwerf SM, Buck DC, Wilmarth PA, Sears LM, David LL, Morton DB, Neve KA.

PLoS One. 2015 Aug 20;10(8):e0136167. doi: 10.1371/journal.pone.0136167. eCollection 2015.

13.

What do European veterinary codes of conduct actually say and mean? A case study approach.

Magalhães-Sant'Ana M, More SJ, Morton DB, Osborne M, Hanlon A.

Vet Rec. 2015 Jun 20;176(25):654. doi: 10.1136/vr.103005. Epub 2015 Apr 10.

PMID:
25861823
14.

Physiological, physical and behavioural changes in dogs (Canis familiaris) when kennelled: testing the validity of stress parameters.

Part CE, Kiddie JL, Hayes WA, Mills DS, Neville RF, Morton DB, Collins LM.

Physiol Behav. 2014 Jun 22;133:260-71. doi: 10.1016/j.physbeh.2014.05.018. Epub 2014 May 24.

PMID:
24866912
15.

Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.

Chang JC, Hazelett DJ, Stewart JA, Morton DB.

Brain Res. 2014 Oct 10;1584:39-51. doi: 10.1016/j.brainres.2013.11.019. Epub 2013 Nov 22.

16.

Phosphodiesterase-8A binds to and regulates Raf-1 kinase.

Brown KM, Day JP, Huston E, Zimmermann B, Hampel K, Christian F, Romano D, Terhzaz S, Lee LC, Willis MJ, Morton DB, Beavo JA, Shimizu-Albergine M, Davies SA, Kolch W, Houslay MD, Baillie GS.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):E1533-42. doi: 10.1073/pnas.1303004110. Epub 2013 Mar 18.

17.

Environmental refinement and quality of life.

Morton DB.

Vet J. 2013 Jan;195(1):4-5. doi: 10.1016/j.tvjl.2012.11.007. No abstract available.

PMID:
23261762
18.

A risk assessment approach to severity classification in animal research.

Morton DB.

Altern Lab Anim. 2012 Oct;40(5):P2-3. No abstract available.

PMID:
23215667
20.

Drosophila gustatory preference behaviors require the atypical soluble guanylyl cyclases.

Vermehren-Schmaedick A, Scudder C, Timmermans W, Morton DB.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2011 Jul;197(7):717-27. doi: 10.1007/s00359-011-0634-9. Epub 2011 Feb 25.

PMID:
21350862
21.

Behavioral responses to hypoxia and hyperoxia in Drosophila larvae: molecular and neuronal sensors.

Morton DB.

Fly (Austin). 2011 Apr-Jun;5(2):119-25. Epub 2011 Apr 1. Review.

22.

A guide to defining and implementing protocols for the welfare assessment of laboratory animals: eleventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement.

Hawkins P, Morton DB, Burman O, Dennison N, Honess P, Jennings M, Lane S, Middleton V, Roughan JV, Wells S, Westwood K; UK Joint Working Group on Refinement BVAAWF/FRAME/RSPCA/UFAW.

Lab Anim. 2011 Jan;45(1):1-13. doi: 10.1258/la.2010.010031. Epub 2010 Dec 1.

PMID:
21123303
23.

Application of the Three Rs to challenge assays used in vaccine testing: tenth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement.

Jennings M, Morton DB, Charton E, Cooper J, Hendriksen C, Martin S, Pearce MC, Price S, Redhead K, Reed N, Simmons H, Spencer S, Willingale H.

Biologicals. 2010 Nov;38(6):684-95. doi: 10.1016/j.biologicals.2010.04.004. Epub 2010 Aug 17.

PMID:
20724180
24.

Behavioral responses to hypoxia in Drosophila larvae are mediated by atypical soluble guanylyl cyclases.

Vermehren-Schmaedick A, Ainsley JA, Johnson WA, Davies SA, Morton DB.

Genetics. 2010 Sep;186(1):183-96. doi: 10.1534/genetics.110.118166. Epub 2010 Jun 30.

25.

Infertility and male mating behavior deficits associated with Pde1c in Drosophila melanogaster.

Morton DB, Clemens-Grisham R, Hazelett DJ, Vermehren-Schmaedick A.

Genetics. 2010 Sep;186(1):159-65. doi: 10.1534/genetics.110.118018. Epub 2010 Jun 15.

26.

A commentary on the animal welfare symposium, with possible actions.

Morton DB.

J Vet Med Educ. 2010 Spring;37(1):107-13. doi: 10.3138/jvme.37.1.107.

PMID:
20378888
27.

Refinements in husbandry, care and common procedures for non-human primates: Ninth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement.

Jennings M, Prescott MJ; Members of the Joint Working Group on Refinement (Primates), Buchanan-Smith HM, Gamble MR, Gore M, Hawkins P, Hubrecht R, Hudson S, Jennings M, Keeley JR, Morris K, Morton DB, Owen S, Pearce PC, Prescott MJ, Robb D, Rumble RJ, Wolfensohn S, Buist D.

Lab Anim. 2009 Apr;43 Suppl 1:1-47. doi: 10.1258/la.2008.007143.

PMID:
19286892
28.

Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases.

Zimmer M, Gray JM, Pokala N, Chang AJ, Karow DS, Marletta MA, Hudson ML, Morton DB, Chronis N, Bargmann CI.

Neuron. 2009 Mar 26;61(6):865-79. doi: 10.1016/j.neuron.2009.02.013.

29.

Synaptic transmission in neurons that express the Drosophila atypical soluble guanylyl cyclases, Gyc-89Da and Gyc-89Db, is necessary for the successful completion of larval and adult ecdysis.

Morton DB, Stewart JA, Langlais KK, Clemens-Grisham RA, Vermehren A.

J Exp Biol. 2008 May;211(Pt 10):1645-56. doi: 10.1242/jeb.014472.

30.

Vaccines and animal welfare.

Morton DB.

Rev Sci Tech. 2007 Apr;26(1):157-63. Review.

PMID:
17633300
31.

Soluble Guanylyl Cyclases in Invertebrates: Targets for NO and O(2).

Morton DB, Vermehren A.

Adv Exp Biol. 2007;1:65-82. No abstract available.

32.

Assessing the welfare of genetically altered mice.

Wells DJ, Playle LC, Enser WE, Flecknell PA, Gardiner MA, Holland J, Howard BR, Hubrecht R, Humphreys KR, Jackson IJ, Lane N, Maconochie M, Mason G, Morton DB, Raymond R, Robinson V, Smith JA, Watt N.

Lab Anim. 2006 Apr;40(2):111-4.

PMID:
16600070
33.

Oxygen-sensitive guanylyl cyclases in insects and their potential roles in oxygen detection and in feeding behaviors.

Vermehren A, Langlais KK, Morton DB.

J Insect Physiol. 2006 Apr;52(4):340-8. Epub 2006 Jan 19. Review.

PMID:
16427074
34.

Comparison of the properties of the five soluble guanylyl cyclase subunits in Drosophila melanogaster.

Morton DB, Langlais KK, Stewart JA, Vermehren A.

J Insect Sci. 2005;5:12. Epub 2005 Apr 19.

35.

Carbon dioxide for euthanasia of laboratory animals.

Raj AB, Leach MC, Morton DB.

Comp Med. 2004 Oct;54(5):470-1. No abstract available.

PMID:
15575359
36.

Atypical soluble guanylyl cyclases in Drosophila can function as molecular oxygen sensors.

Morton DB.

J Biol Chem. 2004 Dec 3;279(49):50651-3. Epub 2004 Oct 13.

37.

Report of the workshop on euthanasia guidelines and practices.

Carbone L, Baumans V, Morton DB.

Altern Lab Anim. 2004 Jun;32 Suppl 1B:445-6.

PMID:
23581115
38.

The welfare of non-human primates in research in the EU.

Morton DB.

Altern Lab Anim. 2004 Jun;32 Suppl 1A:307.

PMID:
23577478
39.
40.

Invertebrates yield a plethora of atypical guanylyl cyclases.

Morton DB.

Mol Neurobiol. 2004 Apr;29(2):97-116. Review.

PMID:
15126679
41.

Husbandry refinements for rats, mice, dogs and non-human primates used in telemetry procedures. Seventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part B.

Hawkins P, Morton DB, Bevan R, Heath K, Kirkwood J, Pearce P, Scott L, Whelan G, Webb A; Joint Working Group on Refinement.

Lab Anim. 2004 Jan;38(1):1-10. No abstract available.

PMID:
14979982
42.

Refinements in telemetry procedures. Seventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part A.

Morton DB, Hawkins P, Bevan R, Heath K, Kirkwood J, Pearce P, Scott L, Whelan G, Webb A; British Veterinary Association Animal Welfare Foundation; Fund for Replacement of Animals in Medical Experiments; Royal Society for the Prevention of Cruelty to Animals; Universities Federation for Animal Welfare.

Lab Anim. 2003 Oct;37(4):261-99. No abstract available.

PMID:
14599304
43.

Cellular signaling in eclosion hormone action.

Morton DB, Simpson PJ.

J Insect Physiol. 2002 Jan;48(1):1-13.

PMID:
12770127
44.

Best animal care practices in the production and control of biologicals.

Morton DB, Hanenberg E, Hogg A, Priebel Valera G, Lund C, Ottiger HP, Gorska P, Borensztejn C, Pereira S, Bousrih M, Blumrich M, Chapek ML, Ramirez A, Thuring J, Umiza A.

Dev Biol (Basel). 2002;111:221-5. No abstract available.

PMID:
12678246
45.
46.

Humane endpoints in the efficacy testing of swine erysipelas vaccines.

Johannes S, Hartinger J, Hendriksen CF, Morton DB, Cussler K.

ALTEX. 2003;20(1):11-5.

47.
48.
49.

Degrees of aversion shown by rats and mice to different concentrations of inhalational anaesthetics.

Leach MC, Bowell VA, Allan TF, Morton DB.

Vet Rec. 2002 Jun 29;150(26):808-15.

PMID:
12120924
50.

Aversion to gaseous euthanasia agents in rats and mice.

Leach MC, Bowell VA, Allan TF, Morton DB.

Comp Med. 2002 Jun;52(3):249-57. Erratum in: Comp Med. 2002 Dec;52(6):498, 572..

PMID:
12102571

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