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Items: 1 to 20 of 53

1.

Insights into pancreatic β cell energy metabolism using rodent β cell models.

Morten KJ, Potter M, Badder L, Sivathondan P, Dragovic R, Neumann A, Gavin J, Shrestha R, Reilly S, Phadwal K, Lodge TA, Borzychowski A, Cookson S, Mitchell C, Morovat A, Simon AK, Uusimaa J, Hynes J, Poulton J.

Version 3. Wellcome Open Res. 2019 Sep 25 [revised 2019 Jan 1];2:14. doi: 10.12688/wellcomeopenres.10535.3. eCollection 2017.

2.

Impact of pharmacological agents on mitochondrial function: a growing opportunity?

Stoker ML, Newport E, Hulit JC, West AP, Morten KJ.

Biochem Soc Trans. 2019 Nov 7. pii: BST20190280. doi: 10.1042/BST20190280. [Epub ahead of print]

PMID:
31696924
3.

Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test.

Tomas C, Lodge TA, Potter M, Elson JL, Newton JL, Morten KJ.

Sci Rep. 2019 Aug 7;9(1):11464. doi: 10.1038/s41598-019-47966-z.

4.

Correction: A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy.

Xu J, Potter M, Tomas C, Elson JL, Morten KJ, Poulton J, Wang N, Jin H, Hou Z, Huang WE.

Analyst. 2019 Jul 7;144(13):4121. doi: 10.1039/c9an90055a. Epub 2019 Jun 7.

PMID:
31173005
5.

A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways.

Agnew T, Goldsworthy M, Aguilar C, Morgan A, Simon M, Hilton H, Esapa C, Wu Y, Cater H, Bentley L, Scudamore C, Poulton J, Morten KJ, Thompson K, He L, Brown SDM, Taylor RW, Bowl MR, Cox RD.

Cell Rep. 2018 Dec 18;25(12):3315-3328.e6. doi: 10.1016/j.celrep.2018.11.080.

6.

Validating the RedMIT/GFP-LC3 Mouse Model by Studying Mitophagy in Autosomal Dominant Optic Atrophy Due to the OPA1Q285STOP Mutation.

Diot A, Agnew T, Sanderson J, Liao C, Carver J, Neves RPD, Gupta R, Guo Y, Waters C, Seto S, Daniels MJ, Dombi E, Lodge T, Morten K, Williams SA, Enver T, Iborra FJ, Votruba M, Poulton J.

Front Cell Dev Biol. 2018 Sep 19;6:103. doi: 10.3389/fcell.2018.00103. eCollection 2018.

7.

A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy.

Xu J, Potter M, Tomas C, Elson JL, Morten KJ, Poulton J, Wang N, Jin H, Hou Z, Huang WE.

Analyst. 2019 Jan 28;144(3):913-920. doi: 10.1039/c8an01437j. Erratum in: Analyst. 2019 Jul 7;144(13):4121.

PMID:
30207334
8.

Mechanisms driving the lactate switch in Chinese hamster ovary cells.

Hartley F, Walker T, Chung V, Morten K.

Biotechnol Bioeng. 2018 Aug;115(8):1890-1903. doi: 10.1002/bit.26603. Epub 2018 Apr 10. Review.

PMID:
29603726
9.

Acute nutritional stress during pregnancy affects placental efficiency, fetal growth and adult glucose homeostasis.

Malik S, Diot A, Morten K, Dombi E, Vatish M, Boyd CAR, Poulton J.

Oncotarget. 2017 Nov 25;8(65):109478-109486. doi: 10.18632/oncotarget.22695. eCollection 2017 Dec 12.

10.

The isolation of primary hepatocytes from human tissue: optimising the use of small non-encapsulated liver resection surplus.

Green CJ, Charlton CA, Wang LM, Silva M, Morten KJ, Hodson L.

Cell Tissue Bank. 2017 Dec;18(4):597-604. doi: 10.1007/s10561-017-9641-6. Epub 2017 Jul 17.

11.

Correction: Is Placental Mitochondrial Function a Regulator that Matches Fetal and Placental Growth to Maternal Nutrient Intake in the Mouse?

Chiaratti MR, Malik S, Diot A, Rapa E, Macleod L, Morten K, Vatish M, Boyd R, Poulton J.

PLoS One. 2017 Feb 3;12(2):e0171795. doi: 10.1371/journal.pone.0171795. eCollection 2017.

12.

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.

Liao C, Ashley N, Diot A, Morten K, Phadwal K, Williams A, Fearnley I, Rosser L, Lowndes J, Fratter C, Ferguson DJ, Vay L, Quaghebeur G, Moroni I, Bianchi S, Lamperti C, Downes SM, Sitarz KS, Flannery PJ, Carver J, Dombi E, East D, Laura M, Reilly MM, Mortiboys H, Prevo R, Campanella M, Daniels MJ, Zeviani M, Yu-Wai-Man P, Simon AK, Votruba M, Poulton J.

Neurology. 2017 Jan 10;88(2):131-142. doi: 10.1212/WNL.0000000000003491. Epub 2016 Dec 14.

13.

The Warburg effect: 80 years on.

Potter M, Newport E, Morten KJ.

Biochem Soc Trans. 2016 Oct 15;44(5):1499-1505. Review.

14.

Modulating mitochondrial quality in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy children.

Diot A, Dombi E, Lodge T, Liao C, Morten K, Carver J, Wells D, Child T, Johnston IG, Williams S, Poulton J.

Biochem Soc Trans. 2016 Aug 15;44(4):1091-100. doi: 10.1042/BST20160095.

15.

Mitophagy plays a central role in mitochondrial ageing.

Diot A, Morten K, Poulton J.

Mamm Genome. 2016 Aug;27(7-8):381-95. doi: 10.1007/s00335-016-9651-x. Epub 2016 Jun 28. Review.

16.

The m.13051G>A mitochondrial DNA mutation results in variable neurology and activated mitophagy.

Dombi E, Diot A, Morten K, Carver J, Lodge T, Fratter C, Ng YS, Liao C, Muir R, Blakely EL, Hargreaves I, Al-Dosary M, Sarkar G, Hickman SJ, Downes SM, Jayawant S, Yu-Wai-Man P, Taylor RW, Poulton J.

Neurology. 2016 May 17;86(20):1921-3. doi: 10.1212/WNL.0000000000002688. Epub 2016 Apr 22. No abstract available.

17.

Monitoring Intracellular Oxygen Concentration: Implications for Hypoxia Studies and Real-Time Oxygen Monitoring.

Potter M, Badder L, Hoade Y, Johnston IG, Morten KJ.

Adv Exp Med Biol. 2016;876:257-263. doi: 10.1007/978-1-4939-3023-4_32.

PMID:
26782220
18.

Using an Integrated -Omics Approach to Identify Key Cellular Processes That Are Disturbed in the Kidney After Brain Death.

Akhtar MZ, Huang H, Kaisar M, Lo Faro ML, Rebolledo R, Morten K, Heather LC, Dona A, Leuvenink HG, Fuggle SV, Kessler BM, Pugh CW, Ploeg RJ.

Am J Transplant. 2016 May;16(5):1421-40. doi: 10.1111/ajt.13626. Epub 2016 Mar 10.

19.

A novel quantitative assay of mitophagy: Combining high content fluorescence microscopy and mitochondrial DNA load to quantify mitophagy and identify novel pharmacological tools against pathogenic heteroplasmic mtDNA.

Diot A, Hinks-Roberts A, Lodge T, Liao C, Dombi E, Morten K, Brady S, Fratter C, Carver J, Muir R, Davis R, Green CJ, Johnston I, Hilton-Jones D, Sue C, Mortiboys H, Poulton J.

Pharmacol Res. 2015 Oct;100:24-35. doi: 10.1016/j.phrs.2015.07.014. Epub 2015 Jul 18.

PMID:
26196248
20.

Is Placental Mitochondrial Function a Regulator that Matches Fetal and Placental Growth to Maternal Nutrient Intake in the Mouse?

Chiaratti MR, Malik S, Diot A, Rapa E, Macleod L, Morten K, Vatish M, Boyd R, Poulton J.

PLoS One. 2015 Jul 1;10(7):e0130631. doi: 10.1371/journal.pone.0130631. eCollection 2015. Erratum in: PLoS One. 2017 Feb 3;12 (2):e0171795.

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