Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 142


Impact of manganese on biofilm formation and cell morphology of Candida parapsilosis clinical isolates with different biofilm forming abilities.

Shafeeq S, Pannanusorn S, Elsharabasy Y, Ramírez-Zavala B, Morschhäuser J, Römling U.

FEMS Yeast Res. 2019 Sep 1;19(6). pii: foz057. doi: 10.1093/femsyr/foz057.


An Intragenic Recombination Event Generates a Snf4-Independent Form of the Essential Protein Kinase Snf1 in Candida albicans.

Mottola A, Morschhäuser J.

mSphere. 2019 Jun 19;4(3). pii: e00352-19. doi: 10.1128/mSphere.00352-19.


In Vitro Activities of the Novel Investigational Tetrazoles VT-1161 and VT-1598 Compared to the Triazole Antifungals against Azole-Resistant Strains and Clinical Isolates of Candida albicans.

Nishimoto AT, Wiederhold NP, Flowers SA, Zhang Q, Kelly SL, Morschhäuser J, Yates CM, Hoekstra WJ, Schotzinger RJ, Garvey EP, Rogers PD.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00341-19. doi: 10.1128/AAC.00341-19. Print 2019 Jun.


Contribution of Clinically Derived Mutations in the Gene Encoding the Zinc Cluster Transcription Factor Mrr2 to Fluconazole Antifungal Resistance and CDR1 Expression in Candida albicans.

Nishimoto AT, Zhang Q, Hazlett B, Morschhäuser J, Rogers PD.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00078-19. doi: 10.1128/AAC.00078-19. Print 2019 May.


Evolution of Fluconazole-Resistant Candida albicans Strains by Drug-Induced Mating Competence and Parasexual Recombination.

Popp C, Ramírez-Zavala B, Schwanfelder S, Krüger I, Morschhäuser J.

mBio. 2019 Feb 5;10(1). pii: e02740-18. doi: 10.1128/mBio.02740-18.


A Hyperactive Form of the Zinc Cluster Transcription Factor Stb5 Causes YOR1 Overexpression and Beauvericin Resistance in Candida albicans.

Ramírez-Zavala B, Manz H, Englert F, Rogers PD, Morschhäuser J.

Antimicrob Agents Chemother. 2018 Nov 26;62(12). pii: e01655-18. doi: 10.1128/AAC.01655-18. Print 2018 Dec.


Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers.

Allert S, Förster TM, Svensson CM, Richardson JP, Pawlik T, Hebecker B, Rudolphi S, Juraschitz M, Schaller M, Blagojevic M, Morschhäuser J, Figge MT, Jacobsen ID, Naglik JR, Kasper L, Mogavero S, Hube B.

mBio. 2018 Jun 5;9(3). pii: e00915-18. doi: 10.1128/mBio.00915-18.


A Global Analysis of Kinase Function in Candida albicans Hyphal Morphogenesis Reveals a Role for the Endocytosis Regulator Akl1.

Bar-Yosef H, Gildor T, Ramírez-Zavala B, Schmauch C, Weissman Z, Pinsky M, Naddaf R, Morschhäuser J, Arkowitz RA, Kornitzer D.

Front Cell Infect Microbiol. 2018 Feb 8;8:17. doi: 10.3389/fcimb.2018.00017. eCollection 2018.


Put3 Positively Regulates Proline Utilization in Candida albicans.

Tebung WA, Omran RP, Fulton DL, Morschhäuser J, Whiteway M.

mSphere. 2017 Dec 13;2(6). pii: e00354-17. doi: 10.1128/mSphere.00354-17. eCollection 2017 Nov-Dec.


Transport Deficiency Is the Molecular Basis of Candida albicans Resistance to Antifungal Oligopeptides.

Schielmann M, Szweda P, Gucwa K, Kawczyński M, Milewska MJ, Martynow D, Morschhäuser J, Milewski S.

Front Microbiol. 2017 Nov 7;8:2154. doi: 10.3389/fmicb.2017.02154. eCollection 2017.


An acquired mechanism of antifungal drug resistance simultaneously enables Candida albicans to escape from intrinsic host defenses.

Hampe IAI, Friedman J, Edgerton M, Morschhäuser J.

PLoS Pathog. 2017 Sep 27;13(9):e1006655. doi: 10.1371/journal.ppat.1006655. eCollection 2017 Sep.


Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains.

Popp C, Hampe IAI, Hertlein T, Ohlsen K, Rogers PD, Morschhäuser J.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00584-17. doi: 10.1128/AAC.00584-17. Print 2017 Jul.


The Snf1-activating kinase Sak1 is a key regulator of metabolic adaptation and in vivo fitness of Candida albicans.

Ramírez-Zavala B, Mottola A, Haubenreißer J, Schneider S, Allert S, Brunke S, Ohlsen K, Hube B, Morschhäuser J.

Mol Microbiol. 2017 Jun;104(6):989-1007. doi: 10.1111/mmi.13674. Epub 2017 Apr 18.


Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.

Ene IV, Lohse MB, Vladu AV, Morschhäuser J, Johnson AD, Bennett RJ.

mBio. 2016 Nov 22;7(6). pii: e01269-16. doi: 10.1128/mBio.01269-16.


Reduced PICD in Monocytes Mounts Altered Neonate Immune Response to Candida albicans.

Dreschers S, Saupp P, Hornef M, Prehn A, Platen C, Morschhäuser J, Orlikowsky TW.

PLoS One. 2016 Nov 21;11(11):e0166648. doi: 10.1371/journal.pone.0166648. eCollection 2016.


Rewiring of the Ppr1 Zinc Cluster Transcription Factor from Purine Catabolism to Pyrimidine Biogenesis in the Saccharomycetaceae.

Tebung WA, Choudhury BI, Tebbji F, Morschhäuser J, Whiteway M.

Curr Biol. 2016 Jul 11;26(13):1677-1687. doi: 10.1016/j.cub.2016.04.064. Epub 2016 Jun 16.


Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch.

Lohse MB, Ene IV, Craik VB, Hernday AD, Mancera E, Morschhäuser J, Bennett RJ, Johnson AD.

Genetics. 2016 Aug;203(4):1679-92. doi: 10.1534/genetics.116.190645. Epub 2016 Jun 8.


The development of fluconazole resistance in Candida albicans - an example of microevolution of a fungal pathogen.

Morschhäuser J.

J Microbiol. 2016 Mar;54(3):192-201. doi: 10.1007/s12275-016-5628-4. Epub 2016 Feb 27. Review.


Induction of Candida albicans drug resistance genes by hybrid zinc cluster transcription factors.

Schneider S, Morschhäuser J.

Antimicrob Agents Chemother. 2015 Jan;59(1):558-69. doi: 10.1128/AAC.04448-14. Epub 2014 Nov 10.


SAGA/ADA complex subunit Ada2 is required for Cap1- but not Mrr1-mediated upregulation of the Candida albicans multidrug efflux pump MDR1.

Ramírez-Zavala B, Mogavero S, Schöller E, Sasse C, Rogers PD, Morschhäuser J.

Antimicrob Agents Chemother. 2014 Sep;58(9):5102-10. doi: 10.1128/AAC.03065-14. Epub 2014 Jun 16.


Control of morphogenesis, protease secretion and gene expression in Candida albicans by the preferred nitrogen source ammonium.

Dunkel N, Biswas K, Hiller E, Fellenberg K, Satheesh SV, Rupp S, Morschhäuser J.

Microbiology. 2014 Aug;160(Pt 8):1599-1608. doi: 10.1099/mic.0.078238-0. Epub 2014 May 19.


Characterization of biofilm formation and the role of BCR1 in clinical isolates of Candida parapsilosis.

Pannanusorn S, Ramírez-Zavala B, Lünsdorf H, Agerberth B, Morschhäuser J, Römling U.

Eukaryot Cell. 2014 Apr;13(4):438-51. doi: 10.1128/EC.00181-13. Epub 2013 Dec 2.


Activation of the Cph1-dependent MAP kinase signaling pathway induces white-opaque switching in Candida albicans.

Ramírez-Zavala B, Weyler M, Gildor T, Schmauch C, Kornitzer D, Arkowitz R, Morschhäuser J.

PLoS Pathog. 2013;9(10):e1003696. doi: 10.1371/journal.ppat.1003696. Epub 2013 Oct 10.


Analysis of a fungus-specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation.

Schillig R, Morschhäuser J.

Mol Microbiol. 2013 Sep;89(5):1003-17. doi: 10.1111/mmi.12327. Epub 2013 Jul 25.


Global transcriptome sequencing identifies chlamydospore specific markers in Candida albicans and Candida dubliniensis.

Palige K, Linde J, Martin R, Böttcher B, Citiulo F, Sullivan DJ, Weber J, Staib C, Rupp S, Hube B, Morschhäuser J, Staib P.

PLoS One. 2013 Apr 15;8(4):e61940. doi: 10.1371/journal.pone.0061940. Print 2013.


Factors supporting cysteine tolerance and sulfite production in Candida albicans.

Hennicke F, Grumbt M, Lermann U, Ueberschaar N, Palige K, Böttcher B, Jacobsen ID, Staib C, Morschhäuser J, Monod M, Hube B, Hertweck C, Staib P.

Eukaryot Cell. 2013 Apr;12(4):604-13. doi: 10.1128/EC.00336-12. Epub 2013 Feb 15.


Roles of different peptide transporters in nutrient acquisition in Candida albicans.

Dunkel N, Hertlein T, Franz R, Reuß O, Sasse C, Schäfer T, Ohlsen K, Morschhäuser J.

Eukaryot Cell. 2013 Apr;12(4):520-8. doi: 10.1128/EC.00008-13. Epub 2013 Feb 2.


White-opaque switching of Candida albicans allows immune evasion in an environment-dependent fashion.

Sasse C, Hasenberg M, Weyler M, Gunzer M, Morschhäuser J.

Eukaryot Cell. 2013 Jan;12(1):50-8. doi: 10.1128/EC.00266-12. Epub 2012 Nov 2.


The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans.

Sasse C, Dunkel N, Schäfer T, Schneider S, Dierolf F, Ohlsen K, Morschhäuser J.

Mol Microbiol. 2012 Nov;86(3):539-56. doi: 10.1111/j.1365-2958.2012.08210.x. Epub 2012 Aug 28.


Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans.

Flowers SA, Barker KS, Berkow EL, Toner G, Chadwick SG, Gygax SE, Morschhäuser J, Rogers PD.

Eukaryot Cell. 2012 Oct;11(10):1289-99. doi: 10.1128/EC.00215-12. Epub 2012 Aug 24.


Inducible and constitutive activation of two polymorphic promoter alleles of the Candida albicans multidrug efflux pump MDR1.

Sasse C, Schillig R, Reimund A, Merk J, Morschhäuser J.

Antimicrob Agents Chemother. 2012 Aug;56(8):4490-4. doi: 10.1128/AAC.00264-12. Epub 2012 May 21.


Tetracycline-inducible gene expression in Candida albicans.

Weyler M, Morschhäuser J.

Methods Mol Biol. 2012;845:201-10. doi: 10.1007/978-1-61779-539-8_13.


Gene deletion in Candida albicans wild-type strains using the SAT1-flipping strategy.

Sasse C, Morschhäuser J.

Methods Mol Biol. 2012;845:3-17. doi: 10.1007/978-1-61779-539-8_1.


Oligopeptide transport and regulation of extracellular proteolysis are required for growth of Aspergillus fumigatus on complex substrates but not for virulence.

Hartmann T, Cairns TC, Olbermann P, Morschhäuser J, Bignell EM, Krappmann S.

Mol Microbiol. 2011 Nov;82(4):917-35. doi: 10.1111/j.1365-2958.2011.07868.x. Epub 2011 Oct 24.


Glutathione utilization by Candida albicans requires a functional glutathione degradation (DUG) pathway and OPT7, an unusual member of the oligopeptide transporter family.

Desai PR, Thakur A, Ganguli D, Paul S, Morschhäuser J, Bachhawat AK.

J Biol Chem. 2011 Dec 2;286(48):41183-94. doi: 10.1074/jbc.M111.272377. Epub 2011 Oct 12.


The transcription factor Ndt80 does not contribute to Mrr1-, Tac1-, and Upc2-mediated fluconazole resistance in Candida albicans.

Sasse C, Schillig R, Dierolf F, Weyler M, Schneider S, Mogavero S, Rogers PD, Morschhäuser J.

PLoS One. 2011;6(9):e25623. doi: 10.1371/journal.pone.0025623. Epub 2011 Sep 27.


Functional dissection of a Candida albicans zinc cluster transcription factor, the multidrug resistance regulator Mrr1.

Schubert S, Popp C, Rogers PD, Morschhäuser J.

Eukaryot Cell. 2011 Aug;10(8):1110-21. doi: 10.1128/EC.05100-11. Epub 2011 Jun 17.


Pathobiology of human-pathogenic fungi.

Brakhage AA, Gross U, Morschhäuser J.

Int J Med Microbiol. 2011 Jun;301(5):367. doi: 10.1016/j.ijmm.2011.04.002. Epub 2011 May 10. No abstract available.


Nitrogen regulation of morphogenesis and protease secretion in Candida albicans.

Morschhäuser J.

Int J Med Microbiol. 2011 Jun;301(5):390-4. doi: 10.1016/j.ijmm.2011.04.005. Epub 2011 May 8. Review.


Regulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans.

Schubert S, Barker KS, Znaidi S, Schneider S, Dierolf F, Dunkel N, Aïd M, Boucher G, Rogers PD, Raymond M, Morschhäuser J.

Antimicrob Agents Chemother. 2011 May;55(5):2212-23. doi: 10.1128/AAC.01343-10. Epub 2011 Mar 14.


Seminal plasma protects human spermatozoa and pathogenic yeasts from capture by dendritic cells.

Rennemeier C, Schwab M, Lermann U, Albert C, Kämmerer U, Frambach T, Morschhäuser J, Dietl J, Staib P.

Hum Reprod. 2011 May;26(5):987-99. doi: 10.1093/humrep/der038. Epub 2011 Feb 23.


Differential requirement of the transcription factor Mcm1 for activation of the Candida albicans multidrug efflux pump MDR1 by its regulators Mrr1 and Cap1.

Mogavero S, Tavanti A, Senesi S, Rogers PD, Morschhäuser J.

Antimicrob Agents Chemother. 2011 May;55(5):2061-6. doi: 10.1128/AAC.01467-10. Epub 2011 Feb 22.


Role of the Npr1 kinase in ammonium transport and signaling by the ammonium permease Mep2 in Candida albicans.

Neuhäuser B, Dunkel N, Satheesh SV, Morschhäuser J.

Eukaryot Cell. 2011 Mar;10(3):332-42. doi: 10.1128/EC.00293-10. Epub 2011 Jan 28.


Loss of heterozygosity at an unlinked genomic locus is responsible for the phenotype of a Candida albicans sap4Δ sap5Δ sap6Δ mutant.

Dunkel N, Morschhäuser J.

Eukaryot Cell. 2011 Jan;10(1):54-62. doi: 10.1128/EC.00281-10. Epub 2010 Nov 19.


New cis-configured aziridine-2-carboxylates as aspartic acid protease inhibitors.

Büchold C, Hemberger Y, Heindl C, Welker A, Degel B, Pfeuffer T, Staib P, Schneider S, Rosenthal PJ, Gut J, Morschhäuser J, Bringmann G, Schirmeister T.

ChemMedChem. 2011 Jan 3;6(1):141-52. doi: 10.1002/cmdc.201000370.


Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2.

Navarathna DH, Das A, Morschhäuser J, Nickerson KW, Roberts DD.

Microbiology. 2011 Jan;157(Pt 1):270-9. doi: 10.1099/mic.0.045005-0. Epub 2010 Sep 30.


Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.

Correia A, Lermann U, Teixeira L, Cerca F, Botelho S, da Costa RM, Sampaio P, Gärtner F, Morschhäuser J, Vilanova M, Pais C.

Infect Immun. 2010 Nov;78(11):4839-49. doi: 10.1128/IAI.00248-10. Epub 2010 Aug 2.


Validation of a self-excising marker in the human pathogen Aspergillus fumigatus by employing the beta-rec/six site-specific recombination system.

Hartmann T, Dümig M, Jaber BM, Szewczyk E, Olbermann P, Morschhäuser J, Krappmann S.

Appl Environ Microbiol. 2010 Sep;76(18):6313-7. doi: 10.1128/AEM.00882-10. Epub 2010 Jul 23.


Baculiferins A-O, O-sulfated pyrrole alkaloids with anti-HIV-1 activity, from the Chinese marine sponge Iotrochota baculifera.

Fan G, Li Z, Shen S, Zeng Y, Yang Y, Xu M, Bruhn T, Bruhn H, Morschhäuser J, Bringmann G, Lin W.

Bioorg Med Chem. 2010 Aug 1;18(15):5466-74. doi: 10.1016/j.bmc.2010.06.052. Epub 2010 Jun 23.


Disruption of homocitrate synthase genes in Candida albicans affects growth but not virulence.

Kur K, Gabriel I, Morschhäuser J, Barchiesi F, Spreghini E, Milewski S.

Mycopathologia. 2010 Dec;170(6):397-402. doi: 10.1007/s11046-010-9337-y. Epub 2010 Jun 23.


Supplemental Content

Loading ...
Support Center