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Items: 1 to 50 of 126

1.

PLGA based particles as "drug reservoir" for antitumor drug delivery: characterization and cytotoxicity studies.

Chronopoulou L, Domenici F, Giantulli S, Brasili F, D'Errico C, Tsaouli G, Tortorella E, Bordi F, Morrone S, Palocci C, Silvestri I.

Colloids Surf B Biointerfaces. 2019 May 7;180:495-502. doi: 10.1016/j.colsurfb.2019.05.006. [Epub ahead of print]

PMID:
31103709
2.

Structural perspectives of antibody-dependent enhancement of infection of dengue virus.

Morrone SR, Lok SM.

Curr Opin Virol. 2019 Mar 4;36:1-8. doi: 10.1016/j.coviro.2019.02.002. [Epub ahead of print] Review.

PMID:
30844538
3.

Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs.

Vomero M, Manganelli V, Barbati C, Colasanti T, Capozzi A, Finucci A, Spinelli FR, Ceccarelli F, Perricone C, Truglia S, Morrone S, Maggio R, Misasi R, Bombardieri M, Di Franco M, Conti F, Sorice M, Valesini G, Alessandri C.

Arthritis Res Ther. 2019 Jan 29;21(1):39. doi: 10.1186/s13075-019-1818-x.

4.

Differential microRNA expression between decidual and peripheral blood natural killer cells in early pregnancy.

Carlino C, Rippo MR, Lazzarini R, Monsurrò V, Morrone S, Angelini S, Trotta E, Stabile H, Bastianelli C, Albertini MC, Olivieri F, Procopio A, Santoni A, Gismondi A.

Hum Reprod. 2018 Dec 1;33(12):2184-2195. doi: 10.1093/humrep/dey323.

PMID:
30388265
5.

Tumor-Targeting Anti-CD20 Antibodies Mediate In Vitro Expansion of Memory Natural Killer Cells: Impact of CD16 Affinity Ligation Conditions and In Vivo Priming.

Capuano C, Battella S, Pighi C, Franchitti L, Turriziani O, Morrone S, Santoni A, Galandrini R, Palmieri G.

Front Immunol. 2018 May 11;9:1031. doi: 10.3389/fimmu.2018.01031. eCollection 2018.

6.

Growth arrest and apoptosis induced by kinesin Eg5 inhibitor K858 and by its 1,3,4-thiadiazoline analogue in tumor cells.

Giantulli S, De Iuliis F, Taglieri L, Carradori S, Menichelli G, Morrone S, Scarpa S, Silvestri I.

Anticancer Drugs. 2018 Aug;29(7):674-681. doi: 10.1097/CAD.0000000000000641.

PMID:
29738338
7.

Digital signaling network drives the assembly of the AIM2-ASC inflammasome.

Matyszewski M, Morrone SR, Sohn J.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E1963-E1972. doi: 10.1073/pnas.1712860115. Epub 2018 Feb 12.

8.

Effect of once-daily, modified-release hydrocortisone versus standard glucocorticoid therapy on metabolism and innate immunity in patients with adrenal insufficiency (DREAM): a single-blind, randomised controlled trial.

Isidori AM, Venneri MA, Graziadio C, Simeoli C, Fiore D, Hasenmajer V, Sbardella E, Gianfrilli D, Pozza C, Pasqualetti P, Morrone S, Santoni A, Naro F, Colao A, Pivonello R, Lenzi A.

Lancet Diabetes Endocrinol. 2018 Mar;6(3):173-185. doi: 10.1016/S2213-8587(17)30398-4. Epub 2017 Dec 8.

PMID:
29229498
9.

Differential effects on membrane permeability and viability of human keratinocyte cells undergoing very low intensity megasonic fields.

Domenici F, Brasili F, Giantulli S, Cerroni B, Bedini A, Giliberti C, Palomba R, Silvestri I, Morrone S, Paradossi G, Mattei M, Bordi F.

Sci Rep. 2017 Nov 28;7(1):16536. doi: 10.1038/s41598-017-16708-4.

10.

Multicolor flow cytometric analysis of TLR2 and TLR9 expression and function in NK cells from patients with ANCA-associated vasculitis.

Scrivo R, Peruzzi G, Gattamelata A, Gross CC, Carletti R, Di Gioia C, Brandt J, Priori R, Morrone S, Santoni A, Valesini G.

Cytometry B Clin Cytom. 2018 May;94(3):412-422. doi: 10.1002/cyto.b.21586. Epub 2017 Aug 29.

11.

Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells.

Pisanu ME, Noto A, De Vitis C, Morrone S, Scognamiglio G, Botti G, Venuta F, Diso D, Jakopin Z, Padula F, Ricci A, Mariotta S, Giovagnoli MR, Giarnieri E, Amelio I, Agostini M, Melino G, Ciliberto G, Mancini R.

Cancer Lett. 2017 Oct 10;406:93-104. doi: 10.1016/j.canlet.2017.07.027. Epub 2017 Aug 7.

PMID:
28797843
12.

Atopic dermatitis IL17A- and IFN-γ-producing lymphocytes: investigation in blood, chronic lesions and APT.

Grieco T, Faina V, Porzia A, Paolino G, Morrone S, Bottoni U, Calvieri S, Mainiero F.

J Eur Acad Dermatol Venereol. 2017 Oct;31(10):e438-e439. doi: 10.1111/jdv.14258. Epub 2017 May 2. No abstract available.

PMID:
28380262
13.

The Glycoside Oleandrin Reduces Glioma Growth with Direct and Indirect Effects on Tumor Cells.

Garofalo S, Grimaldi A, Chece G, Porzia A, Morrone S, Mainiero F, D'Alessandro G, Esposito V, Cortese B, Di Angelantonio S, Trettel F, Limatola C.

J Neurosci. 2017 Apr 5;37(14):3926-3939. doi: 10.1523/JNEUROSCI.2296-16.2017. Epub 2017 Mar 14.

14.

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes.

Farina A, Peruzzi G, Lacconi V, Lenna S, Quarta S, Rosato E, Vestri AR, York M, Dreyfus DH, Faggioni A, Morrone S, Trojanowska M, Farina GA.

Arthritis Res Ther. 2017 Feb 28;19(1):39. doi: 10.1186/s13075-017-1237-9.

15.

CXCR3/CXCL10 Axis Regulates Neutrophil-NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis.

Benigni G, Dimitrova P, Antonangeli F, Sanseviero E, Milanova V, Blom A, van Lent P, Morrone S, Santoni A, Bernardini G.

J Immunol. 2017 Mar 1;198(5):2115-2124. doi: 10.4049/jimmunol.1601359. Epub 2017 Jan 20.

16.

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells.

Antonangeli F, Soriani A, Ricci B, Ponzetta A, Benigni G, Morrone S, Bernardini G, Santoni A.

Oncoimmunology. 2016 Aug 5;5(10):e1218105. eCollection 2016.

17.

Peripheral blood regulatory T cell measurements correlate with serum vitamin D level in patients with psoriasis.

Mattozzi C, Paolino G, Salvi M, Macaluso L, Luci C, Morrone S, Calvieri S, Richetta AG.

Eur Rev Med Pharmacol Sci. 2016 May;20(9):1675-9.

18.

Selective inhibitors of aurora kinases inhibit proliferation, reduce cell viability and impair cell cycle progression in papillary thyroid carcinoma cells.

Baldini E, Tuccilli C, Prinzi N, Sorrenti S, Antonelli A, Fallahi P, Mian C, Barollo S, Catania A, Morrone S, Tartaglia F, Mascagni D, Coccaro C, Pepe M, Filippini A, D'Armiento M, Ulisse S.

J Biol Regul Homeost Agents. 2015 Oct-Dec;29(4):793-803.

PMID:
26753639
19.

The innate immune sensor IFI16 recognizes foreign DNA in the nucleus by scanning along the duplex.

Stratmann SA, Morrone SR, van Oijen AM, Sohn J.

Elife. 2015 Dec 16;4:e11721. doi: 10.7554/eLife.11721.

20.

Synthesis and pharmacological screening of a large library of 1,3,4-thiadiazolines as innovative therapeutic tools for the treatment of prostate cancer and melanoma.

De Monte C, Carradori S, Secci D, D'Ascenzio M, Guglielmi P, Mollica A, Morrone S, Scarpa S, Aglianò AM, Giantulli S, Silvestri I.

Eur J Med Chem. 2015 Nov 13;105:245-62. doi: 10.1016/j.ejmech.2015.10.023. Epub 2015 Oct 22.

PMID:
26498571
21.

Preclinical testing of selective Aurora kinase inhibitors on a medullary thyroid carcinoma-derived cell line.

Tuccilli C, Baldini E, Prinzi N, Morrone S, Sorrenti S, Filippini A, Catania A, Alessandrini S, Rendina R, Coccaro C, D'Armiento M, Ulisse S.

Endocrine. 2016 May;52(2):287-95. doi: 10.1007/s12020-015-0700-0. Epub 2015 Jul 28.

PMID:
26215279
22.

Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC.

Morrone SR, Matyszewski M, Yu X, Delannoy M, Egelman EH, Sohn J.

Nat Commun. 2015 Jul 22;6:7827. doi: 10.1038/ncomms8827.

23.

Single-molecule imaging at high fluorophore concentrations by local activation of dye.

Geertsema HJ, Schulte AC, Spenkelink LM, McGrath WJ, Morrone SR, Sohn J, Mangel WF, Robinson A, van Oijen AM.

Biophys J. 2015 Feb 17;108(4):949-956. doi: 10.1016/j.bpj.2014.12.019.

24.

Effect of surgery on pancreatic tumor-dependent lymphocyte asset: modulation of natural killer cell frequency and cytotoxic function.

Iannone F, Porzia A, Peruzzi G, Birarelli P, Milana B, Sacco L, Dinatale G, Peparini N, Prezioso G, Battella S, Caronna R, Morrone S, Palmieri G, Mainiero F, Chirletti P.

Pancreas. 2015 Apr;44(3):386-93. doi: 10.1097/MPA.0000000000000288.

25.

Multifunctional human CD56 low CD16 low natural killer cells are the prominent subset in bone marrow of both healthy pediatric donors and leukemic patients.

Stabile H, Nisti P, Morrone S, Pagliara D, Bertaina A, Locatelli F, Santoni A, Gismondi A.

Haematologica. 2015 Apr;100(4):489-98. doi: 10.3324/haematol.2014.116053. Epub 2015 Jan 16.

26.

Effects of selective inhibitors of Aurora kinases on anaplastic thyroid carcinoma cell lines.

Baldini E, Tuccilli C, Prinzi N, Sorrenti S, Antonelli A, Gnessi L, Morrone S, Moretti C, Bononi M, Arlot-Bonnemains Y, D'Armiento M, Ulisse S.

Endocr Relat Cancer. 2014 Oct;21(5):797-811. doi: 10.1530/ERC-14-0299. Epub 2014 Jul 29.

PMID:
25074669
27.

Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1.

Soriani A, Iannitto ML, Ricci B, Fionda C, Malgarini G, Morrone S, Peruzzi G, Ricciardi MR, Petrucci MT, Cippitelli M, Santoni A.

J Immunol. 2014 Jul 15;193(2):950-60. doi: 10.4049/jimmunol.1400271. Epub 2014 Jun 9.

28.

Structural and permeability sensitivity of cells to low intensity ultrasound: Infrared and fluorescence evidence in vitro.

Domenici F, Giliberti C, Bedini A, Palomba R, Udroiu I, Di Giambattista L, Pozzi D, Morrone S, Bordi F, Congiu Castellano A.

Ultrasonics. 2014 Apr;54(4):1020-8. doi: 10.1016/j.ultras.2013.12.003. Epub 2013 Dec 14.

PMID:
24370376
29.

Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy.

Morrone SR, Wang T, Constantoulakis LM, Hooy RM, Delannoy MJ, Sohn J.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E62-71. doi: 10.1073/pnas.1313577111. Epub 2013 Dec 23.

30.

Sgol2 provides a regulatory platform that coordinates essential cell cycle processes during meiosis I in oocytes.

Rattani A, Wolna M, Ploquin M, Helmhart W, Morrone S, Mayer B, Godwin J, Xu W, Stemmann O, Pendas A, Nasmyth K.

Elife. 2013 Nov 5;2:e01133. doi: 10.7554/eLife.01133.

31.

CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation.

Ponzetta A, Sciumè G, Benigni G, Antonangeli F, Morrone S, Santoni A, Bernardini G.

J Immunol. 2013 Dec 1;191(11):5684-94. doi: 10.4049/jimmunol.1300090. Epub 2013 Nov 1.

32.

Ultrasound well below the intensity threshold of cavitation can promote efficient uptake of small drug model molecules in fibroblast cells.

Domenici F, Giliberti C, Bedini A, Palomba R, Luongo F, Sennato S, Olmati C, Pozzi D, Morrone S, Congiu Castellano A, Bordi F.

Drug Deliv. 2013 Sep-Oct;20(7):285-95. doi: 10.3109/10717544.2013.836620.

PMID:
24044646
33.

Effects of ultraviolet radiation on FRTL-5 cell growth and thyroid-specific gene expression.

Baldini E, D'Armiento M, Sorrenti S, Del Sordo M, Mocini R, Morrone S, Gnessi L, Curcio F, Ulisse S.

Astrobiology. 2013 Jun;13(6):536-42. doi: 10.1089/ast.2013.0972. Epub 2013 May 22.

PMID:
23697699
34.

Serum levels of functional T-regs in vitiligo: our experience and mini-review of the literature.

Richetta A, D'Epiro S, Salvi M, Campoli M, Giancristoforo S, Mattozzi C, Macaluso L, Luci C, Cantisani C, Carboni V, Zanniello R, Zampetti M, Milana B, Morrone S, Calvieri S.

Eur J Dermatol. 2013 Apr 1;23(2):154-9. doi: 10.1684/ejd.2013.1986. Review.

PMID:
23608724
35.

Decoupling nucleosome recognition from DNA binding dramatically alters the properties of the Chd1 chromatin remodeler.

Patel A, Chakravarthy S, Morrone S, Nodelman IM, McKnight JN, Bowman GD.

Nucleic Acids Res. 2013 Feb 1;41(3):1637-48. doi: 10.1093/nar/gks1440. Epub 2012 Dec 28.

36.

Effects of the Aurora kinases pan-inhibitor SNS-314 mesylate on anaplastic thyroid cancer derived cell lines.

Baldini E, Sorrenti S, D'Armiento E, Guaitoli E, Morrone S, D'Andrea V, Gnessi L, Moretti C, Antonelli A, Catania A, De Antoni E, Ulisse S.

Clin Ter. 2012;163(5):e307-13.

PMID:
23099978
37.

Chemerin regulates NK cell accumulation and endothelial cell morphogenesis in the decidua during early pregnancy.

Carlino C, Trotta E, Stabile H, Morrone S, Bulla R, Soriani A, Iannitto ML, Agostinis C, Mocci C, Minozzi M, Aragona C, Perniola G, Tedesco F, Sozzani S, Santoni A, Gismondi A.

J Clin Endocrinol Metab. 2012 Oct;97(10):3603-12. doi: 10.1210/jc.2012-1102. Epub 2012 Jul 12.

38.

Polyfunctional type-1, -2, and -17 CD8⁺ T cell responses to apoptotic self-antigens correlate with the chronic evolution of hepatitis C virus infection.

Franceschini D, Del Porto P, Piconese S, Trella E, Accapezzato D, Paroli M, Morrone S, Piccolella E, Spada E, Mele A, Sidney J, Sette A, Barnaba V.

PLoS Pathog. 2012;8(6):e1002759. doi: 10.1371/journal.ppat.1002759. Epub 2012 Jun 21.

39.

Downregulation of circulating CD4+ CD25(bright) Foxp3+ T cells by cyclosporine therapy and correlation with clinical response in psoriasis patients: report of three cases.

Richetta AG, Mattozzi C, Salvi M, Giancristoforo S, Cantisani C, D'Epiro S, Calvieri S, Macaluso L, Morrone S.

Int J Dermatol. 2013 Nov;52(11):1437-9. doi: 10.1111/j.1365-4632.2011.05411.x. Epub 2012 Mar 14. No abstract available.

PMID:
22417245
40.

Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment.

Morrone S, Cheng Z, Moon RT, Cong F, Xu W.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1500-5. doi: 10.1073/pnas.1116618109. Epub 2012 Jan 17.

41.

NKG2D/Ligand dysregulation and functional alteration of innate immunity cell populations in pediatric IBD.

La Scaleia R, Stoppacciaro A, Oliva S, Morrone S, Di Nardo G, Santoni A, Cucchiara S, Palmieri G.

Inflamm Bowel Dis. 2012 Oct;18(10):1910-22. doi: 10.1002/ibd.22899. Epub 2012 Jan 31.

PMID:
22294522
42.

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.

Cheng Z, Biechele T, Wei Z, Morrone S, Moon RT, Wang L, Xu W.

Nat Struct Mol Biol. 2011 Oct 9;18(11):1204-10. doi: 10.1038/nsmb.2139.

43.

Aurora kinases are expressed in medullary thyroid carcinoma (MTC) and their inhibition suppresses in vitro growth and tumorigenicity of the MTC derived cell line TT.

Baldini E, Arlot-Bonnemains Y, Sorrenti S, Mian C, Pelizzo MR, De Antoni E, Palermo S, Morrone S, Barollo S, Nesca A, Moretti CG, D'Armiento M, Ulisse S.

BMC Cancer. 2011 Sep 26;11:411. doi: 10.1186/1471-2407-11-411.

44.

Transcriptional modulation of a human monocytic cell line exposed to PM(10) from an urban area.

Bastonini E, Verdone L, Morrone S, Santoni A, Settimo G, Marsili G, La Fortezza M, Di Mauro E, Caserta M.

Environ Res. 2011 Aug;111(6):765-74. doi: 10.1016/j.envres.2011.06.005. Epub 2011 Jul 8.

PMID:
21741637
45.

CD4+ CD25+ T-regulatory cells in psoriasis. Correlation between their numbers and biologics-induced clinical improvement.

Richetta AG, Mattozzi C, Salvi M, Giancristoforo S, D'epiro S, Milana B, Carboni V, Zampetti M, Calvieri S, Morrone S.

Eur J Dermatol. 2011 May-Jun;21(3):344-8. doi: 10.1684/ejd.2011.1362.

PMID:
21680285
46.

CX3CR1 expression defines 2 KLRG1+ mouse NK-cell subsets with distinct functional properties and positioning in the bone marrow.

Sciumè G, De Angelis G, Benigni G, Ponzetta A, Morrone S, Santoni A, Bernardini G.

Blood. 2011 Apr 28;117(17):4467-75. doi: 10.1182/blood-2010-07-297101. Epub 2011 Mar 1.

47.

New marker of tumor cell death revealed by ATR-FTIR spectroscopy.

Di Giambattista L, Pozzi D, Grimaldi P, Gaudenzi S, Morrone S, Castellano AC.

Anal Bioanal Chem. 2011 Mar;399(8):2771-8. doi: 10.1007/s00216-011-4654-7. Epub 2011 Jan 20.

PMID:
21249341
48.

Peripheral and intestinal CD4+ T cells with a regulatory phenotype in pediatric patients with inflammatory bowel disease.

La Scaleia R, Morrone S, Stoppacciaro A, Scarpino S, Antonelli M, Bianchi E, Di Nardo G, Oliva S, Viola F, Cucchiara S, Santoni A, Palmieri G, Uccini S.

J Pediatr Gastroenterol Nutr. 2010 Nov;51(5):563-72. doi: 10.1097/MPG.0b013e3181e4d323.

PMID:
20890221
49.

Evaluation of degranulation and cytokine production in natural killer cells from spondyloarthritis patients at single-cell level.

Scrivo R, Morrone S, Spadaro A, Santoni A, Valesini G.

Cytometry B Clin Cytom. 2011 Jan;80(1):22-7. doi: 10.1002/cyto.b.20549.

50.

Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity state.

Stabile H, Carlino C, Mazza C, Giliani S, Morrone S, Notarangelo LD, Notarangelo LD, Santoni A, Gismondi A.

Blood. 2010 Apr 8;115(14):2818-26. doi: 10.1182/blood-2009-07-235804. Epub 2010 Feb 3.

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