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Items: 40


The tubulin mutation database: A resource for the cytoskeleton community.

Pham CL, Morrissette NS.

Cytoskeleton (Hoboken). 2019 Feb;76(2):186-191. doi: 10.1002/cm.21514. Epub 2019 Feb 4.


From B to A: making an essential cofactor in a human parasite.

Morrissette NS, Goulding CW.

Biochem J. 2017 Aug 30;474(18):3089-3092. doi: 10.1042/BCJ20170446.


Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium.

Francia ME, Dubremetz JF, Morrissette NS.

Cilia. 2016 Feb 4;5:3. doi: 10.1186/s13630-016-0025-5. eCollection 2015. Review.


Extracellular Toxoplasma gondii tachyzoites metabolize and incorporate unnatural sugars into cellular proteins.

Nazarova LA, Ochoa RJ, Jones KA, Morrissette NS, Prescher JA.

Microbes Infect. 2016 Mar;18(3):199-210. doi: 10.1016/j.micinf.2015.11.004. Epub 2015 Dec 11.


An ensemble of specifically targeted proteins stabilizes cortical microtubules in the human parasite Toxoplasma gondii.

Liu J, He Y, Benmerzouga I, Sullivan WJ Jr, Morrissette NS, Murray JM, Hu K.

Mol Biol Cell. 2016 Feb 1;27(3):549-71. doi: 10.1091/mbc.E15-11-0754. Epub 2015 Dec 17.


Compartmentalized Toxoplasma EB1 bundles spindle microtubules to secure accurate chromosome segregation.

Chen CT, Kelly M, Leon Jd, Nwagbara B, Ebbert P, Ferguson DJ, Lowery LA, Morrissette N, Gubbels MJ.

Mol Biol Cell. 2015 Dec 15;26(25):4562-76. doi: 10.1091/mbc.E15-06-0437. Epub 2015 Oct 14.


Ingenious strategies of microbial pathogens.

Morrissette NS, Machner MP.

Mol Biol Cell. 2015 Mar 15;26(6):1007. doi: 10.1091/mbc.E15-01-0011. No abstract available.


Targeting Toxoplasma tubules: tubulin, microtubules, and associated proteins in a human pathogen.

Morrissette N.

Eukaryot Cell. 2015 Jan;14(1):2-12. doi: 10.1128/EC.00225-14. Epub 2014 Nov 7. Review.


Diaryl and heteroaryl sulfides: synthesis via sulfenyl chlorides and evaluation as selective anti-breast-cancer agents.

Yonova IM, Osborne CA, Morrissette NS, Jarvo ER.

J Org Chem. 2014 Mar 7;79(5):1947-53. doi: 10.1021/jo402586v. Epub 2014 Feb 25.


Stereospecific nickel-catalyzed cross-coupling reactions of alkyl Grignard reagents and identification of selective anti-breast-cancer agents.

Yonova IM, Johnson AG, Osborne CA, Moore CE, Morrissette NS, Jarvo ER.

Angew Chem Int Ed Engl. 2014 Feb 24;53(9):2422-2427. doi: 10.1002/anie.201308666. Epub 2014 Jan 29.


A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components.

de Leon JC, Scheumann N, Beatty W, Beck JR, Tran JQ, Yau C, Bradley PJ, Gull K, Wickstead B, Morrissette NS.

Eukaryot Cell. 2013 Jul;12(7):1009-19. doi: 10.1128/EC.00096-13. Epub 2013 May 17.


Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella.

Francia ME, Jordan CN, Patel JD, Sheiner L, Demerly JL, Fellows JD, de Leon JC, Morrissette NS, Dubremetz JF, Striepen B.

PLoS Biol. 2012;10(12):e1001444. doi: 10.1371/journal.pbio.1001444. Epub 2012 Dec 11.


SPM1 stabilizes subpellicular microtubules in Toxoplasma gondii.

Tran JQ, Li C, Chyan A, Chung L, Morrissette NS.

Eukaryot Cell. 2012 Feb;11(2):206-16. doi: 10.1128/EC.05161-11. Epub 2011 Oct 21.


α-Tubulin mutations alter oryzalin affinity and microtubule assembly properties to confer dinitroaniline resistance.

Lyons-Abbott S, Sackett DL, Wloga D, Gaertig J, Morgan RE, Werbovetz KA, Morrissette NS.

Eukaryot Cell. 2010 Dec;9(12):1825-34. doi: 10.1128/EC.00140-10. Epub 2010 Sep 24.


A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division.

Beck JR, Rodriguez-Fernandez IA, de Leon JC, Huynh MH, Carruthers VB, Morrissette NS, Bradley PJ.

PLoS Pathog. 2010 Sep 9;6(9):e1001094. doi: 10.1371/journal.ppat.1001094.


MEC-17 is an alpha-tubulin acetyltransferase.

Akella JS, Wloga D, Kim J, Starostina NG, Lyons-Abbott S, Morrissette NS, Dougan ST, Kipreos ET, Gaertig J.

Nature. 2010 Sep 9;467(7312):218-22. doi: 10.1038/nature09324.


Synthesis and evaluation of oryzalin analogs against Toxoplasma gondii.

Endeshaw MM, Li C, de Leon J, Yao N, Latibeaudiere K, Premalatha K, Morrissette N, Werbovetz KA.

Bioorg Med Chem Lett. 2010 Sep 1;20(17):5179-83. doi: 10.1016/j.bmcl.2010.07.003. Epub 2010 Jul 8.


RNG1 is a late marker of the apical polar ring in Toxoplasma gondii.

Tran JQ, de Leon JC, Li C, Huynh MH, Beatty W, Morrissette NS.

Cytoskeleton (Hoboken). 2010 Sep;67(9):586-98. doi: 10.1002/cm.20469.


Isolating tubulin from nonneural sources.

Sackett DL, Werbovetz KA, Morrissette NS.

Methods Cell Biol. 2010;95:17-32. doi: 10.1016/S0091-679X(10)95002-4. Review.


Host cell invasion by Toxoplasma gondii is temporally regulated by the host microtubule cytoskeleton.

Sweeney KR, Morrissette NS, LaChapelle S, Blader IJ.

Eukaryot Cell. 2010 Nov;9(11):1680-9. doi: 10.1128/EC.00079-10. Epub 2010 Apr 30.


Dinitroaniline activity in Toxoplasma gondii expressing wild-type or mutant alpha-tubulin.

Ma C, Tran J, Gu F, Ochoa R, Li C, Sept D, Werbovetz K, Morrissette N.

Antimicrob Agents Chemother. 2010 Apr;54(4):1453-60. doi: 10.1128/AAC.01150-09. Epub 2010 Feb 9.


The early years of Toxoplasma research: What's past is prologue.

Morrissette NS, Ajioka JW.

Int J Parasitol. 2009 Jul 1;39(8):865-9. doi: 10.1016/j.ijpara.2009.02.010. Epub 2009 Feb 27.


A century of Toxoplasma research.

Ajioka JW, Morrissette NS.

Int J Parasitol. 2009 Jul 1;39(8):859-60. doi: 10.1016/j.ijpara.2009.02.006. Epub 2009 Feb 25. No abstract available.


The cell-penetrating peptide, Pep-1, has activity against intracellular chlamydial growth but not extracellular forms of Chlamydia trachomatis.

Park N, Yamanaka K, Tran D, Chandrangsu P, Akers JC, de Leon JC, Morrissette NS, Selsted ME, Tan M.

J Antimicrob Chemother. 2009 Jan;63(1):115-23. doi: 10.1093/jac/dkn436. Epub 2008 Oct 27.


FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells.

Bell BD, Leverrier S, Weist BM, Newton RH, Arechiga AF, Luhrs KA, Morrissette NS, Walsh CM.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16677-82. doi: 10.1073/pnas.0808597105. Epub 2008 Oct 22.


Secondary mutations correct fitness defects in Toxoplasma gondii with dinitroaniline resistance mutations.

Ma C, Tran J, Li C, Ganesan L, Wood D, Morrissette N.

Genetics. 2008 Oct;180(2):845-56. doi: 10.1534/genetics.108.092494. Epub 2008 Sep 9.


Mutations in alpha-tubulin confer dinitroaniline resistance at a cost to microtubule function.

Ma C, Li C, Ganesan L, Oak J, Tsai S, Sept D, Morrissette NS.

Mol Biol Cell. 2007 Dec;18(12):4711-20. Epub 2007 Sep 19.


Dinitroanilines bind alpha-tubulin to disrupt microtubules.

Morrissette NS, Mitra A, Sept D, Sibley LD.

Mol Biol Cell. 2004 Apr;15(4):1960-8. Epub 2004 Jan 23.


Epsilon-tubulin is an essential component of the centriole.

Dutcher SK, Morrissette NS, Preble AM, Rackley C, Stanga J.

Mol Biol Cell. 2002 Nov;13(11):3859-69.


Cytoskeleton of apicomplexan parasites.

Morrissette NS, Sibley LD.

Microbiol Mol Biol Rev. 2002 Mar;66(1):21-38; table of contents. Review.


Disruption of microtubules uncouples budding and nuclear division in Toxoplasma gondii.

Morrissette NS, Sibley LD.

J Cell Sci. 2002 Mar 1;115(Pt 5):1017-25.


Amphiphysin IIm, a novel amphiphysin II isoform, is required for macrophage phagocytosis.

Gold ES, Morrissette NS, Underhill DM, Guo J, Bassetti M, Aderem A.

Immunity. 2000 Mar;12(3):285-92.


Dynamin 2 is required for phagocytosis in macrophages.

Gold ES, Underhill DM, Morrissette NS, Guo J, McNiven MA, Aderem A.

J Exp Med. 1999 Dec 20;190(12):1849-56.


Isolation and characterization of monoclonal antibodies directed against novel components of macrophage phagosomes.

Morrissette NS, Gold ES, Guo J, Hamerman JA, Ozinsky A, Bedian V, Aderem AA.

J Cell Sci. 1999 Dec;112 ( Pt 24):4705-13.


The macrophage--a cell for all seasons.

Morrissette N, Gold E, Aderem A.

Trends Cell Biol. 1999 May;9(5):199-201. Review. No abstract available.


Toxoplasma gondii: a family of apical antigens associated with the cytoskeleton.

Morrissette NS, Roos DS.

Exp Parasitol. 1998 Jul;89(3):296-303.


Inhibition of Toxoplasma gondii replication by dinitroaniline herbicides.

Stokkermans TJ, Schwartzman JD, Keenan K, Morrissette NS, Tilney LG, Roos DS.

Exp Parasitol. 1996 Dec;84(3):355-70.


Characterization of extreme apical antigens from Toxoplasma gondii.

Morrissette NS, Bedian V, Webster P, Roos DS.

Exp Parasitol. 1994 Nov;79(3):445-59.


Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii.

Roos DS, Donald RG, Morrissette NS, Moulton AL.

Methods Cell Biol. 1994;45:27-63. Review. No abstract available.


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