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Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.

Teixeira VH, Pipinikas CP, Pennycuick A, Lee-Six H, Chandrasekharan D, Beane J, Morris TJ, Karpathakis A, Feber A, Breeze CE, Ntolios P, Hynds RE, Falzon M, Capitanio A, Carroll B, Durrenberger PF, Hardavella G, Brown JM, Lynch AG, Farmery H, Paul DS, Chambers RC, McGranahan N, Navani N, Thakrar RM, Swanton C, Beck S, George PJ, Spira A, Campbell PJ, Thirlwell C, Janes SM.

Nat Med. 2019 Mar;25(3):517-525. doi: 10.1038/s41591-018-0323-0. Epub 2019 Jan 21.


Compact, modular and in-plane AOSLO for high-resolution retinal imaging.

Young LK, Morris TJ, Saunter CD, Smithson HE.

Biomed Opt Express. 2018 Aug 15;9(9):4275-4293. doi: 10.1364/BOE.9.004275. eCollection 2018 Sep 1.


Insights into imprinting from parent-of-origin phased methylomes and transcriptomes.

Zink F, Magnusdottir DN, Magnusson OT, Walker NJ, Morris TJ, Sigurdsson A, Halldorsson GH, Gudjonsson SA, Melsted P, Ingimundardottir H, Kristmundsdottir S, Alexandersson KF, Helgadottir A, Gudmundsson J, Rafnar T, Jonsdottir I, Holm H, Eyjolfsson GI, Sigurdardottir O, Olafsson I, Masson G, Gudbjartsson DF, Thorsteinsdottir U, Halldorsson BV, Stacey SN, Stefansson K.

Nat Genet. 2018 Nov;50(11):1542-1552. doi: 10.1038/s41588-018-0232-7. Epub 2018 Oct 22.


Raman and Infrared Studies of Platinum-Based Drugs: Cisplatin, Carboplatin, Oxaliplatin, Nedaplatin, and Heptaplatin.

Torres M, Khan S, Duplanty M, Lozano HC, Morris TJ, Nguyen T, Rostovtsev YV, DeYonker NJ, Mirsaleh-Kohan N.

J Phys Chem A. 2018 Aug 30;122(34):6934-6952. doi: 10.1021/acs.jpca.8b04023. Epub 2018 Aug 17.


ChAMP: updated methylation analysis pipeline for Illumina BeadChips.

Tian Y, Morris TJ, Webster AP, Yang Z, Beck S, Feber A, Teschendorff AE.

Bioinformatics. 2017 Dec 15;33(24):3982-3984. doi: 10.1093/bioinformatics/btx513.


Suspended solid concentration reduces feeding in freshwater mussels.

Tuttle-Raycraft S, Morris TJ, Ackerman JD.

Sci Total Environ. 2017 Nov 15;598:1160-1168. doi: 10.1016/j.scitotenv.2017.04.127. Epub 2017 May 10.


The effect of Me2SO overexposure during cryopreservation on HOS TE85 and hMSC viability, growth and quality.

Morris TJ, Picken A, Sharp DMC, Slater NKH, Hewitt CJ, Coopman K.

Cryobiology. 2016 Dec;73(3):367-375. doi: 10.1016/j.cryobiol.2016.09.004. Epub 2016 Sep 20.


Loss of reproductive output caused by an invasive species.

Tremblay ME, Morris TJ, Ackerman JD.

R Soc Open Sci. 2016 Apr 6;3(4):150481. doi: 10.1098/rsos.150481. eCollection 2016 Apr.


miR-301a expression: A prognostic marker for prostate cancer.

Damodaran C, Das TP, Papu John AM, Suman S, Kolluru V, Morris TJ, Faber EN, Rai SN, Messer JC, Alatassi H, Ankem MK.

Urol Oncol. 2016 Aug;34(8):336.e13-20. doi: 10.1016/j.urolonc.2016.03.009. Epub 2016 Apr 26.


Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells.

Butcher LM, Ito M, Brimpari M, Morris TJ, Soares FAC, Ährlund-Richter L, Carey N, Vallier L, Ferguson-Smith AC, Beck S.

Nat Commun. 2016 Jan 29;7:10458. doi: 10.1038/ncomms10458.


A nuclear fraction of turnip crinkle virus capsid protein is important for elicitation of the host resistance response.

Kang SH, Qu F, Morris TJ.

Virus Res. 2015 Dec 2;210:264-70. doi: 10.1016/j.virusres.2015.08.014. Epub 2015 Aug 20.


Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours.

Pipinikas CP, Dibra H, Karpathakis A, Feber A, Novelli M, Oukrif D, Fusai G, Valente R, Caplin M, Meyer T, Teschendorff A, Bell C, Morris TJ, Salomoni P, Luong TV, Davidson B, Beck S, Thirlwell C.

Endocr Relat Cancer. 2015 Jun;22(3):L13-8. doi: 10.1530/ERC-15-0108. Epub 2015 Apr 21. No abstract available.


A spectrum of HRT-dependent hypersensitive responses elicited by the 52 amino acid N-terminus of turnip crinkle virus capsid protein and its mutants.

Kang SH, Qu F, Morris TJ.

Virus Res. 2015 Mar 16;200:30-4. doi: 10.1016/j.virusres.2015.01.020. Epub 2015 Feb 2.


Generation of an Attenuated, Cross-Protective Pepino mosaic virus Variant Through Alignment-Guided Mutagenesis of the Viral Capsid Protein.

Chewachong GM, Miller SA, Blakeslee JJ, Francis DM, Morris TJ, Qu F.

Phytopathology. 2015 Jan;105(1):126-34. doi: 10.1094/PHYTO-01-14-0018-R.


Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data.

Morris TJ, Beck S.

Methods. 2015 Jan 15;72:3-8. doi: 10.1016/j.ymeth.2014.08.011. Epub 2014 Sep 16. Review.


oxBS-450K: a method for analysing hydroxymethylation using 450K BeadChips.

Stewart SK, Morris TJ, Guilhamon P, Bulstrode H, Bachman M, Balasubramanian S, Beck S.

Methods. 2015 Jan 15;72:9-15. doi: 10.1016/j.ymeth.2014.08.009. Epub 2014 Aug 28.


Assessing the stability of an ALPAO deformable mirror for feed-forward operation.

Bitenc U, Bharmal NA, Morris TJ, Myers RM.

Opt Express. 2014 May 19;22(10):12438-51. doi: 10.1364/OE.22.012438.


Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.

Steegenga WT, Boekschoten MV, Lute C, Hooiveld GJ, de Groot PJ, Morris TJ, Teschendorff AE, Butcher LM, Beck S, Müller M.

Age (Dordr). 2014 Jun;36(3):9648. doi: 10.1007/s11357-014-9648-x. Epub 2014 May 2.


Using high-density DNA methylation arrays to profile copy number alterations.

Feber A, Guilhamon P, Lechner M, Fenton T, Wilson GA, Thirlwell C, Morris TJ, Flanagan AM, Teschendorff AE, Kelly JD, Beck S.

Genome Biol. 2014 Feb 3;15(2):R30. doi: 10.1186/gb-2014-15-2-r30.


Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming.

Ellis PJ, Morris TJ, Skinner BM, Sargent CA, Vickers MH, Gluckman PD, Gilmour S, Affara NA.

BMC Genomics. 2014 Jan 21;15:49. doi: 10.1186/1471-2164-15-49.


Turnip crinkle virus coat protein inhibits the basal immune response to virus invasion in Arabidopsis by binding to the NAC transcription factor TIP.

Donze T, Qu F, Twigg P, Morris TJ.

Virology. 2014 Jan 20;449:207-14. doi: 10.1016/j.virol.2013.11.018. Epub 2013 Dec 8.


ChAMP: 450k Chip Analysis Methylation Pipeline.

Morris TJ, Butcher LM, Feber A, Teschendorff AE, Chakravarthy AR, Wojdacz TK, Beck S.

Bioinformatics. 2014 Feb 1;30(3):428-30. doi: 10.1093/bioinformatics/btt684. Epub 2013 Dec 12.


Amphipathic polymer-mediated uptake of trehalose for dimethyl sulfoxide-free human cell cryopreservation.

Sharp DM, Picken A, Morris TJ, Hewitt CJ, Coopman K, Slater NK.

Cryobiology. 2013 Dec;67(3):305-11. doi: 10.1016/j.cryobiol.2013.09.002. Epub 2013 Sep 14.


Triticum mosaic poacevirus enlists P1 rather than HC-Pro to suppress RNA silencing-mediated host defense.

Tatineni S, Qu F, Li R, Morris TJ, French R.

Virology. 2012 Nov 10;433(1):104-15. doi: 10.1016/j.virol.2012.07.016. Epub 2012 Aug 9.


An evaluation of patient and physician satisfaction with controlled-release oxybutynin 15 mg as a one-step daily dose in elderly and non-elderly patients with overactive bladder: results of the STOP study.

Aaron LE, Morris TJ, Jahshan P, Reiz JL.

Curr Med Res Opin. 2012 Aug;28(8):1369-79. doi: 10.1185/03007995.2012.709837. Epub 2012 Jul 23.


Virus infections in wild plant populations are both frequent and often unapparent.

Prendeville HR, Ye X, Morris TJ, Pilson D.

Am J Bot. 2012 Jun;99(6):1033-42. doi: 10.3732/ajb.1100509. Epub 2012 May 29.


Tritimovirus P1 functions as a suppressor of RNA silencing and an enhancer of disease symptoms.

Young BA, Stenger DC, Qu F, Morris TJ, Tatineni S, French R.

Virus Res. 2012 Feb;163(2):672-7. doi: 10.1016/j.virusres.2011.12.019. Epub 2011 Dec 31.


Robust RNAi-based resistance to mixed infection of three viruses in soybean plants expressing separate short hairpins from a single transgene.

Zhang X, Sato S, Ye X, Dorrance AE, Morris TJ, Clemente TE, Qu F.

Phytopathology. 2011 Nov;101(11):1264-9. doi: 10.1094/PHYTO-02-11-0056.


The capsid protein of Turnip crinkle virus overcomes two separate defense barriers to facilitate systemic movement of the virus in Arabidopsis.

Cao M, Ye X, Willie K, Lin J, Zhang X, Redinbaugh MG, Simon AE, Morris TJ, Qu F.

J Virol. 2010 Aug;84(15):7793-802. doi: 10.1128/JVI.02643-09. Epub 2010 May 26.


Transcriptional profiling of rats subjected to gestational undernourishment: implications for the developmental variations in metabolic traits.

Morris TJ, Vickers M, Gluckman P, Gilmour S, Affara N.

PLoS One. 2009 Sep 29;4(9):e7271. doi: 10.1371/journal.pone.0007271.


A current landscape of provincial perinatal data collection in Canada.

Massey KA, Magee LA, Dale S, Claydon J, Morris TJ, von Dadelszen P, Liston RM, Ansermino JM; Canadian Perinatal Network Collaborative Group and the British Columbia Perinatal Health Program.

J Obstet Gynaecol Can. 2009 Mar;31(3):236-246. doi: 10.1016/S1701-2163(16)34122-6.


Increasing rates of contralateral prophylactic mastectomy among patients with ductal carcinoma in situ.

Tuttle TM, Jarosek S, Habermann EB, Arrington A, Abraham A, Morris TJ, Virnig BA.

J Clin Oncol. 2009 Mar 20;27(9):1362-7. doi: 10.1200/JCO.2008.20.1681. Epub 2009 Feb 17.


What is SNOMED CT and why should the ISSHP care?

Massey KA, Ansermino JM, von Dadelszen P, Morris TJ, Liston RM, Magee LA.

Hypertens Pregnancy. 2009 Feb;28(1):119-21. doi: 10.1080/10641950802601294.


Wheat streak mosaic virus Lacking Helper Component-Proteinase Is Competent to Produce Disease Synergism in Double Infections with Maize chlorotic mottle virus.

Stenger DC, Young BA, Qu F, Morris TJ, French R.

Phytopathology. 2007 Oct;97(10):1213-21. doi: 10.1094/PHYTO-97-10-1213.


Arabidopsis DRB4, AGO1, AGO7, and RDR6 participate in a DCL4-initiated antiviral RNA silencing pathway negatively regulated by DCL1.

Qu F, Ye X, Morris TJ.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14732-7. doi: 10.1073/pnas.0805760105. Epub 2008 Sep 17.


A versatile assay for the identification of RNA silencing suppressors based on complementation of viral movement.

Powers JG, Sit TL, Qu F, Morris TJ, Kim KH, Lommel SA.

Mol Plant Microbe Interact. 2008 Jul;21(7):879-90. doi: 10.1094/MPMI-21-7-0879.


Increasing use of contralateral prophylactic mastectomy for breast cancer patients: a trend toward more aggressive surgical treatment.

Tuttle TM, Habermann EB, Grund EH, Morris TJ, Virnig BA.

J Clin Oncol. 2007 Nov 20;25(33):5203-9. Epub 2007 Oct 22.


Optimizing Rayleigh laser guide star range-gate depth during initial loop closing.

Morris TJ, Wilson RW.

Opt Lett. 2007 Jul 15;32(14):2004-6.


Leaving a lasting impression: ear mold impressions as middle ear foreign bodies.

Jacob A, Morris TJ, Welling DB.

Ann Otol Rhinol Laryngol. 2006 Dec;115(12):912-6.


Expression of Aedes trypsin-modulating oostatic factor on the virion of TMV: A potential larvicide.

Borovsky D, Rabindran S, Dawson WO, Powell CA, Iannotti DA, Morris TJ, Shabanowitz J, Hunt DF, DeBondt HL, DeLoof A.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):18963-8. Epub 2006 Dec 5.


In vitro and in vivo characterization of a combination chemotherapy formulation consisting of vinorelbine and phosphatidylserine.

Webb MS, Johnstone S, Morris TJ, Kennedy A, Gallagher R, Harasym N, Harasym T, Shew CR, Tardi P, Dragowska WH, Mayer LD, Bally MB.

Eur J Pharm Biopharm. 2007 Mar;65(3):289-99. Epub 2006 Oct 17.


Studying the mechanosensitivity of voltage-gated channels using oocyte patches.

Morris CE, Juranka PF, Lin W, Morris TJ, Laitko U.

Methods Mol Biol. 2006;322:315-29. Review.


Common HEXB polymorphisms reduce serum HexA and HexB enzymatic activities, potentially masking Tay-Sachs disease carrier identification.

Vallance H, Morris TJ, Coulter-Mackie M, Lim-Steele J, Kaback M.

Mol Genet Metab. 2006 Feb;87(2):122-7. Epub 2005 Dec 13.


RDR6 has a broad-spectrum but temperature-dependent antiviral defense role in Nicotiana benthamiana.

Qu F, Ye X, Hou G, Sato S, Clemente TE, Morris TJ.

J Virol. 2005 Dec;79(24):15209-17.


Suppressors of RNA silencing encoded by plant viruses and their role in viral infections.

Qu F, Morris TJ.

FEBS Lett. 2005 Oct 31;579(26):5958-64. Epub 2005 Sep 2. Review.


A novel ferroportin mutation in a Canadian family with autosomal dominant hemochromatosis.

Morris TJ, Litvinova MM, Ralston D, Mattman A, Holmes D, Lockitch G.

Blood Cells Mol Dis. 2005 Nov-Dec;35(3):309-14. Epub 2005 Aug 18.


RNA silencing-suppressor function of Turnip crinkle virus coat protein cannot be attributed to its interaction with the Arabidopsis protein TIP.

Choi CW, Qu F, Ren T, Ye X, Morris TJ.

J Gen Virol. 2004 Nov;85(Pt 11):3415-3420. doi: 10.1099/vir.0.80326-0.


Preserved antigenicity of HIV-1 p24 produced and purified in high yields from plants inoculated with a tobacco mosaic virus (TMV)-derived vector.

Pérez-Filgueira DM, Brayfield BP, Phiri S, Borca MV, Wood C, Morris TJ.

J Virol Methods. 2004 Nov;121(2):201-8.


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