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Items: 1 to 50 of 82

1.

Corrigendum to "Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR" [DNA Repair 6 (2007) 1536-1544].

Jowsey P, Morrice NA, Hastie CJ, MacLauchlan H, Toth R, Rouse J.

DNA Repair (Amst). 2018 May;65:80. doi: 10.1016/j.dnarep.2017.10.012. Epub 2018 Feb 12. No abstract available.

PMID:
29449168
2.

Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin Cancer.

Unbekandt M, Belshaw S, Bower J, Clarke M, Cordes J, Crighton D, Croft DR, Drysdale MJ, Garnett MJ, Gill K, Gray C, Greenhalgh DA, Hall JAM, Konczal J, Lilla S, McArthur D, McConnell P, McDonald L, McGarry L, McKinnon H, McMenemy C, Mezna M, Morrice NA, Munro J, Naylor G, Rath N, Schüttelkopf AW, Sime M, Olson MF.

Cancer Res. 2018 Apr 15;78(8):2096-2114. doi: 10.1158/0008-5472.CAN-17-2870. Epub 2018 Jan 30.

PMID:
29382705
3.

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis.

Zibrova D, Vandermoere F, Göransson O, Peggie M, Mariño KV, Knierim A, Spengler K, Weigert C, Viollet B, Morrice NA, Sakamoto K, Heller R.

Biochem J. 2017 Mar 7;474(6):983-1001. doi: 10.1042/BCJ20160980.

PMID:
28008135
4.

Phosphorylation of a splice variant of collapsin response mediator protein 2 in the nucleus of tumour cells links cyclin dependent kinase-5 to oncogenesis.

Grant NJ, Coates PJ, Woods YL, Bray SE, Morrice NA, Hastie CJ, Lamont DJ, Carey FA, Sutherland C.

BMC Cancer. 2015 Nov 10;15:885. doi: 10.1186/s12885-015-1691-1.

5.

Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16.

Shehata SN, Deak M, Morrice NA, Ohta E, Hunter RW, Kalscheuer VM, Sakamoto K.

Biochem J. 2015 Aug 1;469(3):409-20. doi: 10.1042/BJ20150486. Epub 2015 Jun 11.

6.

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.

Ross EA, Smallie T, Ding Q, O'Neil JD, Cunliffe HE, Tang T, Rosner DR, Klevernic I, Morrice NA, Monaco C, Cunningham AF, Buckley CD, Saklatvala J, Dean JL, Clark AR.

J Immunol. 2015 Jul 1;195(1):265-76. doi: 10.4049/jimmunol.1402826. Epub 2015 May 22.

7.

K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin.

Kristariyanto YA, Abdul Rehman SA, Campbell DG, Morrice NA, Johnson C, Toth R, Kulathu Y.

Mol Cell. 2015 Apr 2;58(1):83-94. doi: 10.1016/j.molcel.2015.01.041. Epub 2015 Mar 5.

8.

Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.

Kristariyanto YA, Choi SY, Rehman SA, Ritorto MS, Campbell DG, Morrice NA, Toth R, Kulathu Y.

Biochem J. 2015 Apr 15;467(2):345-52. doi: 10.1042/BJ20141502.

9.

Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate.

Ducommun S, Deak M, Sumpton D, Ford RJ, Núñez Galindo A, Kussmann M, Viollet B, Steinberg GR, Foretz M, Dayon L, Morrice NA, Sakamoto K.

Cell Signal. 2015 May;27(5):978-88. doi: 10.1016/j.cellsig.2015.02.008. Epub 2015 Feb 13.

10.

Fumarate induces redox-dependent senescence by modifying glutathione metabolism.

Zheng L, Cardaci S, Jerby L, MacKenzie ED, Sciacovelli M, Johnson TI, Gaude E, King A, Leach JD, Edrada-Ebel R, Hedley A, Morrice NA, Kalna G, Blyth K, Ruppin E, Frezza C, Gottlieb E.

Nat Commun. 2015 Jan 23;6:6001. doi: 10.1038/ncomms7001.

11.

SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.

Henriksson E, Säll J, Gormand A, Wasserstrom S, Morrice NA, Fritzen AM, Foretz M, Campbell DG, Sakamoto K, Ekelund M, Degerman E, Stenkula KG, Göransson O.

J Cell Sci. 2015 Feb 1;128(3):472-86.

12.

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.

Ritorto MS, Ewan R, Perez-Oliva AB, Knebel A, Buhrlage SJ, Wightman M, Kelly SM, Wood NT, Virdee S, Gray NS, Morrice NA, Alessi DR, Trost M.

Nat Commun. 2014 Aug 27;5:4763. doi: 10.1038/ncomms5763.

13.

Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis.

Douglas P, Ye R, Trinkle-Mulcahy L, Neal JA, De Wever V, Morrice NA, Meek K, Lees-Miller SP.

Biosci Rep. 2014 Jun 25;34(3). pii: e00113. doi: 10.1042/BSR20140051.

14.

Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.

Makrantoni V, Corbishley SJ, Rachidi N, Morrice NA, Robinson DA, Stark MJ.

PLoS One. 2014 Feb 18;9(2):e89399. doi: 10.1371/journal.pone.0089399. eCollection 2014.

15.

Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cells.

Gantke T, Boussouf S, Janzen J, Morrice NA, Howell S, Mühlberger E, Ley SC.

Biochem J. 2013 Jun 1;452(2):359-65. doi: 10.1042/BJ20121873.

16.

Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex.

Erazo T, Moreno A, Ruiz-Babot G, Rodríguez-Asiain A, Morrice NA, Espadamala J, Bayascas JR, Gómez N, Lizcano JM.

Mol Cell Biol. 2013 Apr;33(8):1671-86. doi: 10.1128/MCB.01246-12. Epub 2013 Feb 19.

17.

Pseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation.

Ura S, Pollitt AY, Veltman DM, Morrice NA, Machesky LM, Insall RH.

Curr Biol. 2012 Apr 10;22(7):553-61. doi: 10.1016/j.cub.2012.02.020. Epub 2012 Mar 1.

18.
19.

A screen for novel phosphoinositide 3-kinase effector proteins.

Dixon MJ, Gray A, Boisvert FM, Agacan M, Morrice NA, Gourlay R, Leslie NR, Downes CP, Batty IH.

Mol Cell Proteomics. 2011 Apr;10(4):M110.003178. doi: 10.1074/mcp.M110.003178. Epub 2011 Jan 24.

20.

Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction.

Lewis AE, Sommer L, Arntzen MØ, Strahm Y, Morrice NA, Divecha N, D'Santos CS.

Mol Cell Proteomics. 2011 Feb;10(2):M110.003376. doi: 10.1074/mcp.M110.003376. Epub 2010 Nov 3.

21.

Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry.

Pozo-Guisado E, Campbell DG, Deak M, Alvarez-Barrientos A, Morrice NA, Alvarez IS, Alessi DR, Martín-Romero FJ.

J Cell Sci. 2010 Sep 15;123(Pt 18):3084-93. doi: 10.1242/jcs.067215. Epub 2010 Aug 24.

22.

Prophossi: automating expert validation of phosphopeptide-spectrum matches from tandem mass spectrometry.

Martin DM, Nett IR, Vandermoere F, Barber JD, Morrice NA, Ferguson MA.

Bioinformatics. 2010 Sep 1;26(17):2153-9. doi: 10.1093/bioinformatics/btq341. Epub 2010 Jul 22.

23.

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization.

Nichols RJ, Dzamko N, Morrice NA, Campbell DG, Deak M, Ordureau A, Macartney T, Tong Y, Shen J, Prescott AR, Alessi DR.

Biochem J. 2010 Sep 15;430(3):393-404. doi: 10.1042/BJ20100483.

24.

In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification.

Blomster HA, Imanishi SY, Siimes J, Kastu J, Morrice NA, Eriksson JE, Sistonen L.

J Biol Chem. 2010 Jun 18;285(25):19324-9. doi: 10.1074/jbc.M110.106955. Epub 2010 Apr 13.

25.

PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.

Yan L, Mieulet V, Burgess D, Findlay GM, Sully K, Procter J, Goris J, Janssens V, Morrice NA, Lamb RF.

Mol Cell. 2010 Mar 12;37(5):633-42. doi: 10.1016/j.molcel.2010.01.031.

26.

Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1).

Dettori R, Sonzogni S, Meyer L, Lopez-Garcia LA, Morrice NA, Zeuzem S, Engel M, Piiper A, Neimanis S, Frödin M, Biondi RM.

J Biol Chem. 2009 Oct 30;284(44):30318-27. doi: 10.1074/jbc.M109.051151. Epub 2009 Sep 1.

27.

Sprouty2 association with B-Raf is regulated by phosphorylation and kinase conformation.

Brady SC, Coleman ML, Munro J, Feller SM, Morrice NA, Olson MF.

Cancer Res. 2009 Sep 1;69(17):6773-81. doi: 10.1158/0008-5472.CAN-08-4447. Epub 2009 Aug 18.

28.

Regulation of the inducible nuclear dual-specificity phosphatase DUSP5 by ERK MAPK.

Kucharska A, Rushworth LK, Staples C, Morrice NA, Keyse SM.

Cell Signal. 2009 Dec;21(12):1794-805. doi: 10.1016/j.cellsig.2009.07.015. Epub 2009 Aug 7.

PMID:
19666109
29.

Differential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signaling.

Dubois F, Vandermoere F, Gernez A, Murphy J, Toth R, Chen S, Geraghty KM, Morrice NA, MacKintosh C.

Mol Cell Proteomics. 2009 Nov;8(11):2487-99. doi: 10.1074/mcp.M800544-MCP200. Epub 2009 Aug 1.

30.

Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes.

Trinkle-Mulcahy L, Boulon S, Lam YW, Urcia R, Boisvert FM, Vandermoere F, Morrice NA, Swift S, Rothbauer U, Leonhardt H, Lamond A.

J Cell Biol. 2008 Oct 20;183(2):223-39. doi: 10.1083/jcb.200805092.

31.

A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis.

Towler MC, Fogarty S, Hawley SA, Pan DA, Martin DM, Morrice NA, McCarthy A, Galardo MN, Meroni SB, Cigorraga SB, Ashworth A, Sakamoto K, Hardie DG.

Biochem J. 2008 Nov 15;416(1):1-14. doi: 10.1042/BJ20081447.

PMID:
18774945
32.

Identification and characterization of FUS/TLS as a new target of ATM.

Gardiner M, Toth R, Vandermoere F, Morrice NA, Rouse J.

Biochem J. 2008 Oct 15;415(2):297-307. doi: 10.1042/BJ20081135.

PMID:
18620545
33.

Identification of serine phosphorylation in mitochondrial uncoupling protein 1.

Carroll AM, Porter RK, Morrice NA.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):1060-5. doi: 10.1016/j.bbabio.2008.04.030. Epub 2008 Apr 30.

34.

Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin.

Spycher C, Miller ES, Townsend K, Pavic L, Morrice NA, Janscak P, Stewart GS, Stucki M.

J Cell Biol. 2008 Apr 21;181(2):227-40. doi: 10.1083/jcb.200709008. Epub 2008 Apr 14.

35.

TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation.

Clark K, Middelbeek J, Lasonder E, Dulyaninova NG, Morrice NA, Ryazanov AG, Bresnick AR, Figdor CG, van Leeuwen FN.

J Mol Biol. 2008 May 9;378(4):790-803. doi: 10.1016/j.jmb.2008.02.057. Epub 2008 Mar 4.

36.

Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7.

Clark K, Middelbeek J, Morrice NA, Figdor CG, Lasonder E, van Leeuwen FN.

PLoS One. 2008 Mar 26;3(3):e1876. doi: 10.1371/journal.pone.0001876.

37.

Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1.

Richardson C, Rafiqi FH, Karlsson HK, Moleleki N, Vandewalle A, Campbell DG, Morrice NA, Alessi DR.

J Cell Sci. 2008 Mar 1;121(Pt 5):675-84. doi: 10.1242/jcs.025312. Epub 2008 Feb 12.

38.

Novel procedure to investigate the effect of phosphorylation on protein complex formation in vitro and in cells.

Rembutsu M, Soutar MP, Van Aalten L, Gourlay R, Hastie CJ, McLauchlan H, Morrice NA, Cole AR, Sutherland C.

Biochemistry. 2008 Feb 19;47(7):2153-61. doi: 10.1021/bi702030w. Epub 2008 Jan 26.

PMID:
18220421
39.

Identification of the flavoprotein of succinate dehydrogenase and aconitase as in vitro mitochondrial substrates of Fgr tyrosine kinase.

Salvi M, Morrice NA, Brunati AM, Toninello A.

FEBS Lett. 2007 Dec 11;581(29):5579-85. Epub 2007 Nov 13.

40.

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators.

Chen S, Murphy J, Toth R, Campbell DG, Morrice NA, Mackintosh C.

Biochem J. 2008 Jan 15;409(2):449-59.

PMID:
17995453
41.
42.

Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR.

Geraghty KM, Chen S, Harthill JE, Ibrahim AF, Toth R, Morrice NA, Vandermoere F, Moorhead GB, Hardie DG, MacKintosh C.

Biochem J. 2007 Oct 15;407(2):231-41.

43.

Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR.

Jowsey P, Morrice NA, Hastie CJ, McLauchlan H, Toth R, Rouse J.

DNA Repair (Amst). 2007 Oct 1;6(10):1536-44. Epub 2007 Jun 5. Erratum in: DNA Repair (Amst). 2018 Feb 12;:.

PMID:
17553757
44.

Pim kinase substrate identification and specificity.

Peng C, Knebel A, Morrice NA, Li X, Barringer K, Li J, Jakes S, Werneburg B, Wang L.

J Biochem. 2007 Mar;141(3):353-62. Epub 2007 Jan 18.

PMID:
17234686
45.

Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress.

Zagórska A, Pozo-Guisado E, Boudeau J, Vitari AC, Rafiqi FH, Thastrup J, Deak M, Campbell DG, Morrice NA, Prescott AR, Alessi DR.

J Cell Biol. 2007 Jan 1;176(1):89-100. Epub 2006 Dec 26.

46.

Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS.

McCoy CE, macdonald A, Morrice NA, Campbell DG, Deak M, Toth R, McIlrath J, Arthur JS.

Biochem J. 2007 Mar 15;402(3):491-501.

47.

Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation.

Göransson O, Deak M, Wullschleger S, Morrice NA, Prescott AR, Alessi DR.

J Cell Sci. 2006 Oct 1;119(Pt 19):4059-70. Epub 2006 Sep 12.

48.

Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62.

Stafford MJ, Morrice NA, Peggie MW, Cohen P.

FEBS Lett. 2006 Jul 10;580(16):4010-4. Epub 2006 Jun 15.

49.

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.

Vitari AC, Thastrup J, Rafiqi FH, Deak M, Morrice NA, Karlsson HK, Alessi DR.

Biochem J. 2006 Jul 1;397(1):223-31.

50.

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

Al-Hakim AK, Göransson O, Deak M, Toth R, Campbell DG, Morrice NA, Prescott AR, Alessi DR.

J Cell Sci. 2005 Dec 1;118(Pt 23):5661-73.

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