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Items: 25


Using next-generation sequencing to determine diversity of horse intestinal worms: identifying the equine 'nemabiome'.

Mitchell CJ, O'Sullivan CM, Pinloche E, Wilkinson T, Morphew RM, McEwan NR.

J Equine Sci. 2019 Mar;30(1):1-5. doi: 10.1294/jes.30.1. Epub 2019 Apr 3.


The importance of extracellular vesicle purification for downstream analysis: A comparison of differential centrifugation and size exclusion chromatography for helminth pathogens.

Davis CN, Phillips H, Tomes JJ, Swain MT, Wilkinson TJ, Brophy PM, Morphew RM.

PLoS Negl Trop Dis. 2019 Feb 27;13(2):e0007191. doi: 10.1371/journal.pntd.0007191. eCollection 2019 Feb.


X-ray structure of Fasciola hepatica Sigma class glutathione transferase 1 reveals a disulfide bond to support stability in gastro-intestinal environment.

Line K, Isupov MN, LaCourse EJ, Cutress DJ, Morphew RM, Brophy PM, Littlechild JA.

Sci Rep. 2019 Jan 29;9(1):902. doi: 10.1038/s41598-018-37531-5.


Genome Sequencing and Pan-Genome Analysis of 23 Corallococcus spp. Strains Reveal Unexpected Diversity, With Particular Plasticity of Predatory Gene Sets.

Livingstone PG, Morphew RM, Whitworth DE.

Front Microbiol. 2018 Dec 19;9:3187. doi: 10.3389/fmicb.2018.03187. eCollection 2018.


Smell of Infection: A Novel, Noninvasive Method for Detection of Fish Excretory-Secretory Proteins.

Pawluk RJ, Stuart R, Garcia de Leaniz C, Cable J, Morphew RM, Brophy PM, Consuegra S.

J Proteome Res. 2019 Mar 1;18(3):1371-1379. doi: 10.1021/acs.jproteome.8b00953. Epub 2019 Jan 9.


Polyomic tools for an emerging livestock parasite, the rumen fluke Calicophoron daubneyi; identifying shifts in rumen functionality.

Huson KM, Morphew RM, Allen NR, Hegarty MJ, Worgan HJ, Girdwood SE, Jones EL, Phillips HC, Vickers M, Swain M, Smith D, Kingston-Smith AH, Brophy PM.

Parasit Vectors. 2018 Dec 4;11(1):617. doi: 10.1186/s13071-018-3225-6.


Genome Analysis, Metabolic Potential, and Predatory Capabilities of Herpetosiphon llansteffanense sp. nov.

Livingstone PG, Morphew RM, Cookson AR, Whitworth DE.

Appl Environ Microbiol. 2018 Oct 30;84(22). pii: e01040-18. doi: 10.1128/AEM.01040-18. Print 2018 Nov 15.


Purification of native Sigma class glutathione transferase from Fasciola hepatica.

Duncan J, Cutress D, Morphew RM, Brophy PM.

Mol Biochem Parasitol. 2018 Jun;222:45-50. doi: 10.1016/j.molbiopara.2018.04.006. Epub 2018 Apr 27.


Worms at the Royal Welsh Show.

Tyson F, Brophy PM, Morphew RM, Allen T, Pennington C, Thomas E.

Vet Rec. 2017 Oct 7;181(14):376-377. doi: 10.1136/vr.j4548. No abstract available.


Myxobacteria Are Able to Prey Broadly upon Clinically-Relevant Pathogens, Exhibiting a Prey Range Which Cannot Be Explained by Phylogeny.

Livingstone PG, Morphew RM, Whitworth DE.

Front Microbiol. 2017 Aug 22;8:1593. doi: 10.3389/fmicb.2017.01593. eCollection 2017.


Saprotrophic proteomes of biotypes of the witches' broom pathogen Moniliophthora perniciosa.

Pierre S, Griffith GW, Morphew RM, Mur LAJ, Scott IM.

Fungal Biol. 2017 Sep;121(9):743-753. doi: 10.1016/j.funbio.2017.05.004. Epub 2017 May 31.


Exploring and Expanding the Fatty-Acid-Binding Protein Superfamily in Fasciola Species.

Morphew RM, Wilkinson TJ, Mackintosh N, Jahndel V, Paterson S, McVeigh P, Abbas Abidi SM, Saifullah K, Raman M, Ravikumar G, LaCourse J, Maule A, Brophy PM.

J Proteome Res. 2016 Sep 2;15(9):3308-21. doi: 10.1021/acs.jproteome.6b00331. Epub 2016 Aug 16.


The effects of PPO activity on the proteome of ingested red clover and implications for improving the nutrition of grazing cattle.

Hart EH, Onime LA, Davies TE, Morphew RM, Kingston-Smith AH.

J Proteomics. 2016 Jun 1;141:67-76. doi: 10.1016/j.jprot.2016.04.023. Epub 2016 Apr 21.


Calmodulin disruption impacts growth and motility in juvenile liver fluke.

McCammick EM, McVeigh P, McCusker P, Timson DJ, Morphew RM, Brophy PM, Marks NJ, Mousley A, Maule AG.

Parasit Vectors. 2016 Jan 27;9:46. doi: 10.1186/s13071-016-1324-9.


RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.

McVeigh P, McCammick EM, McCusker P, Morphew RM, Mousley A, Abidi A, Saifullah KM, Muthusamy R, Gopalakrishnan R, Spithill TW, Dalton JP, Brophy PM, Marks NJ, Maule AG.

PLoS Negl Trop Dis. 2014 Sep 25;8(9):e3185. doi: 10.1371/journal.pntd.0003185. eCollection 2014 Sep.


Time-dependent tegumental surface changes in juvenile Fasciola gigantica in response to triclabendazole treatment in goat.

Shareef PA, Brennan GP, McVeigh P, Khan MA, Morphew RM, Mousley A, Marks NJ, Saifullah MK, Brophy PM, Maule AG, Abidi SM.

Acta Trop. 2014 Aug;136:108-17. doi: 10.1016/j.actatropica.2014.04.011. Epub 2014 Apr 15.


Proteomics and in silico approaches to extend understanding of the glutathione transferase superfamily of the tropical liver fluke Fasciola gigantica.

Morphew RM, Eccleston N, Wilkinson TJ, McGarry J, Perally S, Prescott M, Ward D, Williams D, Paterson S, Raman M, Ravikumar G, Khalid Saifullah M, Abbas Abidi SM, McVeigh P, Maule AG, Brophy PM, LaCourse EJ.

J Proteome Res. 2012 Dec 7;11(12):5876-89. doi: 10.1021/pr300654w. Epub 2012 Nov 28.


Identification of the major proteins of an immune modulating fraction from adult Fasciola hepatica released by Nonidet P40.

Morphew RM, Hamilton CM, Wright HA, Dowling DJ, O'Neill SM, Brophy PM.

Vet Parasitol. 2013 Jan 31;191(3-4):379-85. doi: 10.1016/j.vetpar.2012.08.029. Epub 2012 Sep 11.


The soluble proteome phenotypes of ivermectin resistant and ivermectin susceptible Haemonchus contortus females compared.

Hart EH, Morphew RM, Bartley DJ, Millares P, Wolf BT, Brophy PM, Hamilton JV.

Vet Parasitol. 2012 Nov 23;190(1-2):104-13. doi: 10.1016/j.vetpar.2012.06.009. Epub 2012 Jun 17.


Anthelmintic metabolism in parasitic helminths: proteomic insights.

Brophy PM, MacKintosh N, Morphew RM.

Parasitology. 2012 Aug;139(9):1205-17. doi: 10.1017/S003118201200087X. Epub 2012 Jul 10. Review.


The Sigma class glutathione transferase from the liver fluke Fasciola hepatica.

LaCourse EJ, Perally S, Morphew RM, Moxon JV, Prescott M, Dowling DJ, O'Neill SM, Kipar A, Hetzel U, Hoey E, Zafra R, Buffoni L, Pérez Arévalo J, Brophy PM.

PLoS Negl Trop Dis. 2012;6(5):e1666. doi: 10.1371/journal.pntd.0001666. Epub 2012 May 29.


Towards delineating functions within the fasciola secreted cathepsin l protease family by integrating in vivo based sub-proteomics and phylogenetics.

Morphew RM, Wright HA, Lacourse EJ, Porter J, Barrett J, Woods DJ, Brophy PM.

PLoS Negl Trop Dis. 2011 Jan 4;5(1):e937. doi: 10.1371/journal.pntd.0000937.


The Fasciola hepatica tegumental antigen suppresses dendritic cell maturation and function.

Hamilton CM, Dowling DJ, Loscher CE, Morphew RM, Brophy PM, O'Neill SM.

Infect Immun. 2009 Jun;77(6):2488-98. doi: 10.1128/IAI.00919-08. Epub 2009 Mar 30.


Comparative proteomics of excretory-secretory proteins released by the liver fluke Fasciola hepatica in sheep host bile and during in vitro culture ex host.

Morphew RM, Wright HA, LaCourse EJ, Woods DJ, Brophy PM.

Mol Cell Proteomics. 2007 Jun;6(6):963-72. Epub 2007 Feb 17.

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