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Intestinal co-colonization with different carbapenemase-producing Enterobacterales isolates is not a rare event in an OXA-48 endemic area.

Hernández-García M, Pérez-Viso B, Navarro-San Francisco C, Baquero F, Morosini MI, Ruiz-Garbajosa P, Cantón R.

EClinicalMedicine. 2019 Oct 17;15:72-79. doi: 10.1016/j.eclinm.2019.09.005. eCollection 2019 Oct.


Mechanisms of action and antimicrobial activity of ceftobiprole.

Morosini MI, Díez-Aguilar M, Cantón R.

Rev Esp Quimioter. 2019 Sep;32 Suppl 3:3-10. Review.


Hypermucoviscous Klebsiella pneumoniae: A challenge in community acquired infection.

Sánchez-López J, García-Caballero A, Navarro-San Francisco C, Quereda C, Ruiz-Garbajosa P, Navas E, Dronda F, Morosini MI, Cantón R, Diez-Aguilar M.

IDCases. 2019 May 3;17:e00547. doi: 10.1016/j.idcr.2019.e00547. eCollection 2019.


Outbreak of NDM-1+CTX-M-15+DHA-1-producing Klebsiella pneumoniae high-risk clone in Spain owing to an undetectable colonised patient from Pakistan.

Hernández-García M, Pérez-Viso B, León-Sampedro R, Navarro-San Francisco C, López-Fresneña N, Díaz-Agero C, Morosini MI, Ruiz-Garbajosa P, Cantón R.

Int J Antimicrob Agents. 2019 Aug;54(2):233-239. doi: 10.1016/j.ijantimicag.2019.05.021. Epub 2019 Jun 4.


Whole-genome sequencing reveals nosocomial Clostridioides difficile transmission and a previously unsuspected epidemic scenario.

García-Fernández S, Frentrup M, Steglich M, Gonzaga A, Cobo M, López-Fresneña N, Cobo J, Morosini MI, Cantón R, Del Campo R, Nübel U.

Sci Rep. 2019 May 6;9(1):6959. doi: 10.1038/s41598-019-43464-4.


Recommendations of the Spanish Antibiogram Committee (COESANT) for selecting antimicrobial agents and concentrations for in vitro susceptibility studies using automated systems.

Cantón R, Oliver A, Alós JI, de Benito N, Bou G, Campos J, Calvo J, Canut A, Castillo J, Cercenado E, Domínguez MÁ, Fernández-Cuenca F, Guinea J, Larrosa N, Liñares J, López-Cerero L, López-Navas A, Marco F, Mirelis B, Moreno-Romo MÁ, Morosini MI, Navarro F, Oteo J, Pascual Á, Pérez-Trallero E, Pérez-Vázquez M, Soriano A, Torres C, Vila J, Martínez-Martínez L.

Enferm Infecc Microbiol Clin. 2019 Mar 13. pii: S0213-005X(19)30135-1. doi: 10.1016/j.eimc.2019.01.017. [Epub ahead of print] Review. English, Spanish.


Urinary tract infections and antimicrobial resistance.

Morosini MI, Del Campo R.

Rev Clin Esp. 2019 Apr;219(3):149-150. doi: 10.1016/j.rce.2018.12.003. Epub 2019 Mar 4. English, Spanish. No abstract available.


Direct antimicrobial susceptibility testing from the blood culture pellet obtained for MALDI-TOF identification of Enterobacterales and Pseudomonas aeruginosa.

López-Pintor JM, Navarro-San Francisco C, Sánchez-López J, García-Caballero A, Loza Fernández de Bobadilla E, Morosini MI, Cantón R.

Eur J Clin Microbiol Infect Dis. 2019 Jun;38(6):1095-1104. doi: 10.1007/s10096-019-03498-y. Epub 2019 Feb 2.


Impact of De-escalation on Prognosis of Patients With Bacteremia due to Enterobacteriaceae: A Post Hoc Analysis From a Multicenter Prospective Cohort.

Palacios-Baena ZR, Delgado-Valverde M, Valiente Méndez A, Almirante B, Gómez-Zorrilla S, Borrell N, Corzo JE, Gurguí M, De la Calle C, García-Álvarez L, Ramos L, Gozalo M, Morosini MI, Molina J, Causse M, Pascual Á, Rodríguez-Baño J; REIPI/GEIRAS-SEIMC Bacteraemia-MIC Group .

Clin Infect Dis. 2019 Aug 30;69(6):956-962. doi: 10.1093/cid/ciy1032.


Early prosthetic endocarditis caused by Stenotrophomonas maltophilia.

Morte E, Tolmos M, Halperin A, Morosini MI, Cantón R, Hermida JM.

Med Mal Infect. 2018 Dec;48(8):543-546. doi: 10.1016/j.medmal.2018.09.004. Epub 2018 Oct 15. Review. No abstract available.


Emergence and dissemination of colistin-resistant Klebsiella pneumoniae isolates expressing OXA-48 plus CTX-M-15 in patients not previously treated with colistin in a Spanish university hospital.

Barragán-Prada H, Ruiz-Hueso P, Tedim AP, González-Candelas F, Galán JC, Cantón R, Morosini MI.

Diagn Microbiol Infect Dis. 2019 Feb;93(2):147-153. doi: 10.1016/j.diagmicrobio.2018.08.014. Epub 2018 Sep 8.


Antimicrobial susceptibility of non-fermenting Gram-negative pathogens isolated from cystic fibrosis patients.

Díez-Aguilar M, Ekkelenkamp M, Morosini MI, Merino I, de Dios Caballero J, Jones M, van Westreenen M, Tunney MM, Cantón R, Fluit AC.

Int J Antimicrob Agents. 2019 Jan;53(1):84-88. doi: 10.1016/j.ijantimicag.2018.09.001. Epub 2018 Sep 19.


Changes in bacterial hospital epidemiology.

Morosini MI, Cantón R.

Rev Esp Quimioter. 2018 Sep;31 Suppl 1:23-26. Review.


First Report of an OXA-48- and CTX-M-213-Producing Kluyvera Species Clone Recovered from Patients Admitted in a University Hospital in Madrid, Spain.

Hernández-García M, León-Sampedro R, Pérez-Viso B, Morosini MI, López-Fresneña N, Díaz-Agero C, Coque TM, Ruiz-Garbajosa P, Cantón R.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01238-18. doi: 10.1128/AAC.01238-18. Print 2018 Nov.


Performance of CHROMID® Colistin R agar, a new chromogenic medium for screening of colistin-resistant Enterobacterales.

García-Fernández S, García-Castillo M, Ruiz-Garbajosa P, Morosini MI, Bala Y, Zambardi G, Cantón R.

Diagn Microbiol Infect Dis. 2019 Jan;93(1):1-4. doi: 10.1016/j.diagmicrobio.2018.07.008. Epub 2018 Aug 7.


Susceptibility testing and detection of β-lactam resistance mechanisms in Enterobacteriaceae: a multicentre national proficiency study.

Díez-Aguilar M, Conejo MC, Morosini MI, Tormo Palop N, Gimeno C, Cantón R, Pascual Á.

Int J Antimicrob Agents. 2018 Apr;51(4):612-619. doi: 10.1016/j.ijantimicag.2017.12.008. Epub 2017 Dec 21.


Use of Calgary and Microfluidic BioFlux Systems To Test the Activity of Fosfomycin and Tobramycin Alone and in Combination against Cystic Fibrosis Pseudomonas aeruginosa Biofilms.

Díez-Aguilar M, Morosini MI, Köksal E, Oliver A, Ekkelenkamp M, Cantón R.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01650-17. doi: 10.1128/AAC.01650-17. Print 2018 Jan.


The endless increase of antibiotic resistance in Enterobacteriaceae and the activity of new compounds to face the challenge.

Morosini MI.

Enferm Infecc Microbiol Clin. 2017 Oct;35(8):477-479. doi: 10.1016/j.eimc.2017.08.007. English, Spanish. No abstract available.


[Dalbavancin breakpoints and recommendations for in vitro study of its activity].

Cantón R, Díez-Aguilar M, Morosini MI.

Enferm Infecc Microbiol Clin. 2017 Jan;35 Suppl 1:15-21. doi: 10.1016/S0213-005X(17)30030-7. Spanish.


CHROMagar mSuperCARBA performance in carbapenem-resistant Enterobacteriaceae isolates characterized at molecular level and routine surveillance rectal swab specimens.

García-Fernández S, Hernández-García M, Valverde A, Ruiz-Garbajosa P, Morosini MI, Cantón R.

Diagn Microbiol Infect Dis. 2017 Mar;87(3):207-209. doi: 10.1016/j.diagmicrobio.2016.11.014. Epub 2016 Nov 25.


Gut eradication of VIM-1 producing ST9 Klebsiella oxytoca after fecal microbiota transplantation for diarrhea caused by a Clostridium difficile hypervirulent R027 strain.

García-Fernández S, Morosini MI, Cobo M, Foruny JR, López-Sanromán A, Cobo J, Romero J, Cantón R, Del Campo R.

Diagn Microbiol Infect Dis. 2016 Dec;86(4):470-471. doi: 10.1016/j.diagmicrobio.2016.09.004. Epub 2016 Sep 16.


Etest® versus broth microdilution for ceftaroline MIC determination with Staphylococcus aureus: results from PREMIUM, a European multicentre study.

Cantón R, Livermore DM, Morosini MI, Díaz-Regañón J, Rossolini GM; PREMIUM Study Group.

J Antimicrob Chemother. 2017 Feb;72(2):431-436. doi: 10.1093/jac/dkw442. Epub 2016 Oct 20.


First description of late recurrence of catheter-associated bacteraemia due to Cellulosimicrobium cellulans.

Ponce-Alonso M, Del Campo R, Fortun J, Cantón R, Morosini MI.

Enferm Infecc Microbiol Clin. 2017 Feb;35(2):131-133. doi: 10.1016/j.eimc.2016.05.003. Epub 2016 Jun 8. No abstract available.


Emergence of cfr-Mediated Linezolid Resistance in a Methicillin-Resistant Staphylococcus aureus Epidemic Clone Isolated from Patients with Cystic Fibrosis.

de Dios Caballero J, Pastor MD, Vindel A, Máiz L, Yagüe G, Salvador C, Cobo M, Morosini MI, del Campo R, Cantón R; GEIFQ Study Group.

Antimicrob Agents Chemother. 2015 Dec 14;60(3):1878-82. doi: 10.1128/AAC.02067-15.


Is a New Standard Needed for Diffusion Methods for In Vitro Susceptibility Testing of Fosfomycin against Pseudomonas aeruginosa?

Díez-Aguilar M, Martínez-García L, Cantón R, Morosini MI.

Antimicrob Agents Chemother. 2015 Dec 7;60(2):1158-61. doi: 10.1128/AAC.02237-15. Print 2016 Feb.


Detection of Carbapenemase Production in a Collection of Enterobacteriaceae with Characterized Resistance Mechanisms from Clinical and Environmental Origins by Use of Both Carba NP and Blue-Carba Tests.

García-Fernández S, Morosini MI, Gijón D, Beatobe L, Ruiz-Garbajosa P, Domínguez L, Cantón R, Valverde A.

J Clin Microbiol. 2016 Feb;54(2):464-6. doi: 10.1128/JCM.02580-15. Epub 2015 Nov 25.


Comparison of different methods for identification of species of the genus Raoultella: report of 11 cases of Raoultella causing bacteraemia and literature review.

Ponce-Alonso M, Rodríguez-Rojas L, Del Campo R, Cantón R, Morosini MI.

Clin Microbiol Infect. 2016 Mar;22(3):252-7. doi: 10.1016/j.cmi.2015.10.035. Epub 2015 Nov 11. Review.


Antimicrobial Activity of Fosfomycin-Tobramycin Combination against Pseudomonas aeruginosa Isolates Assessed by Time-Kill Assays and Mutant Prevention Concentrations.

Díez-Aguilar M, Morosini MI, Tedim AP, Rodríguez I, Aktaş Z, Cantón R.

Antimicrob Agents Chemother. 2015 Oct;59(10):6039-45. doi: 10.1128/AAC.00822-15. Epub 2015 Jul 20.


Performance of EUCAST and CLSI approaches for co-amoxiclav susceptibility testing conditions for clinical categorization of a collection of Escherichia coli isolates with characterized resistance phenotypes.

Díez-Aguilar M, Morosini MI, López-Cerero L, Pascual Á, Calvo J, Martínez-Martínez L, Marco F, Vila J, Ortega A, Oteo J, Cantón R.

J Antimicrob Chemother. 2015 Aug;70(8):2306-10. doi: 10.1093/jac/dkv088. Epub 2015 Apr 21.


In vitro activity of ceftazidime, ceftaroline and aztreonam alone and in combination with avibactam against European Gram-negative and Gram-positive clinical isolates.

Testa R, Cantón R, Giani T, Morosini MI, Nichols WW, Seifert H, Stefanik D, Rossolini GM, Nordmann P.

Int J Antimicrob Agents. 2015 Jun;45(6):641-6. doi: 10.1016/j.ijantimicag.2014.12.033. Epub 2015 Feb 17.


Breakpoints for carbapenemase-producing Enterobacteriaceae: is the problem solved?

Cantón R, Canut A, Morosini MI, Oliver A.

Enferm Infecc Microbiol Clin. 2014 Dec;32 Suppl 4:33-40. doi: 10.1016/S0213-005X(14)70172-7. Review.


Evaluation of the eazyplex® SuperBug CRE system for rapid detection of carbapenemases and ESBLs in clinical Enterobacteriaceae isolates recovered at two Spanish hospitals.

García-Fernández S, Morosini MI, Marco F, Gijón D, Vergara A, Vila J, Ruiz-Garbajosa P, Cantón R.

J Antimicrob Chemother. 2015 Apr;70(4):1047-50. doi: 10.1093/jac/dku476. Epub 2014 Nov 26.


Evaluation of a loop-mediated isothermal amplification-based methodology to detect carbapenemase carriage in Acinetobacter clinical isolates.

Vergara A, Zboromyrska Y, Mosqueda N, Morosini MI, García-Fernández S, Roca I, Cantón R, Marco F, Vila J.

Antimicrob Agents Chemother. 2014 Dec;58(12):7538-40. doi: 10.1128/AAC.03870-14. Epub 2014 Sep 15.


[Antimicrobial spectrum of ceftaroline. In vitro activity against methicillin-resistant staphylococci].

Cercenado E, Morosini MI.

Enferm Infecc Microbiol Clin. 2014 Mar;32 Suppl 2:8-14. doi: 10.1016/S0213-005X(14)70152-1. Spanish.


Rapid detection of β-lactamase-hydrolyzing extended-spectrum cephalosporins in Enterobacteriaceae by use of the new chromogenic βLacta test.

Morosini MI, García-Castillo M, Tato M, Gijón D, Valverde A, Ruiz-Garbajosa P, Cantón R.

J Clin Microbiol. 2014 May;52(5):1741-4. doi: 10.1128/JCM.03614-13. Epub 2014 Feb 26.


Characterization of variables that may influence ozenoxacin in susceptibility testing, including MIC and MBC values.

Tato M, López Y, Morosini MI, Moreno-Bofarull A, Garcia-Alonso F, Gargallo-Viola D, Vila J, Cantón R.

Diagn Microbiol Infect Dis. 2014 Mar;78(3):263-7. doi: 10.1016/j.diagmicrobio.2013.11.010. Epub 2013 Nov 15.


Melioidosis in traveler from Africa to Spain.

Morosini MI, Quereda C, Gil H, Anda P, Núñez-Murga M, Cantón R, López-Vélez R.

Emerg Infect Dis. 2013 Oct;19(10):1656-9. doi: 10.3201/eid1910.121785.


In vitro activity of fosfomycin against a collection of clinical Pseudomonas aeruginosa isolates from 16 Spanish hospitals: establishing the validity of standard broth microdilution as susceptibility testing method.

Díez-Aguilar M, Morosini MI, del Campo R, García-Castillo M, Zamora J, Cantón R.

Antimicrob Agents Chemother. 2013 Nov;57(11):5701-3. doi: 10.1128/AAC.00589-13. Epub 2013 Aug 12.


Multiclonal dispersal of KPC genes following the emergence of non-ST258 KPC-producing Klebsiella pneumoniae clones in Madrid, Spain.

Ruiz-Garbajosa P, Curiao T, Tato M, Gijón D, Pintado V, Valverde A, Baquero F, Morosini MI, Coque TM, Cantón R.

J Antimicrob Chemother. 2013 Nov;68(11):2487-92. doi: 10.1093/jac/dkt237. Epub 2013 Jun 20.


Population structure and antimicrobial susceptibility of both nonpersistent and persistent Pseudomonas aeruginosa isolates recovered from cystic fibrosis patients.

Fernández-Olmos A, García-Castillo M, Alba JM, Morosini MI, Lamas A, Romero B, Galán JC, del Campo R, Cantón R.

J Clin Microbiol. 2013 Aug;51(8):2761-5. doi: 10.1128/JCM.00802-13. Epub 2013 Jun 12.


Assessment of the Phoenix™ automated system and EUCAST breakpoints for antimicrobial susceptibility testing against isolates expressing clinically relevant resistance mechanisms.

Giani T, Morosini MI, D'Andrea MM, García-Castillo M, Rossolini GM, Cantón R.

Clin Microbiol Infect. 2012 Nov;18(11):E452-8. doi: 10.1111/j.1469-0691.2012.03980.x. Epub 2012 Aug 22.


Emergence of a mutL mutation causing multilocus sequence typing-pulsed-field gel electrophoresis discrepancy among Pseudomonas aeruginosa isolates from a cystic fibrosis patient.

García-Castillo M, Máiz L, Morosini MI, Rodríguez-Baños M, Suarez L, Fernández-Olmos A, Baquero F, Cantón R, del Campo R.

J Clin Microbiol. 2012 May;50(5):1777-8. doi: 10.1128/JCM.05478-11. Epub 2012 Feb 8.


Clinical and microbiological features of a cystic fibrosis patient chronically colonized with Pandoraea sputorum identified by combining 16S rRNA sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry.

Fernández-Olmos A, Morosini MI, Lamas A, García-Castillo M, García-García L, Cantón R, Máiz L.

J Clin Microbiol. 2012 Mar;50(3):1096-8. doi: 10.1128/JCM.05730-11. Epub 2011 Dec 14.


[Phenotypic detection of resistance mechanisms in gram-positive bacteria].

Morosini MI, Cercenado E, Ardanuy C, Torres C.

Enferm Infecc Microbiol Clin. 2012 Jun;30(6):325-32. doi: 10.1016/j.eimc.2011.09.009. Epub 2011 Nov 29. Review. Spanish.


MALDI-TOF MS improves routine identification of non-fermenting Gram negative isolates from cystic fibrosis patients.

Fernández-Olmos A, García-Castillo M, Morosini MI, Lamas A, Máiz L, Cantón R.

J Cyst Fibros. 2012 Jan;11(1):59-62. doi: 10.1016/j.jcf.2011.09.001. Epub 2011 Oct 2.


Reidentification of Streptococcus bovis isolates causing bacteremia according to the new taxonomy criteria: still an issue?

Romero B, Morosini MI, Loza E, Rodríguez-Baños M, Navas E, Cantón R, Campo RD.

J Clin Microbiol. 2011 Sep;49(9):3228-33. doi: 10.1128/JCM.00524-11. Epub 2011 Jul 13.


Emergence and spread of antibiotic resistance following exposure to antibiotics.

Cantón R, Morosini MI.

FEMS Microbiol Rev. 2011 Sep;35(5):977-91. doi: 10.1111/j.1574-6976.2011.00295.x. Epub 2011 Jul 29. Review.


Wide dispersion of ST175 clone despite high genetic diversity of carbapenem-nonsusceptible Pseudomonas aeruginosa clinical strains in 16 Spanish hospitals.

García-Castillo M, Del Campo R, Morosini MI, Riera E, Cabot G, Willems R, van Mansfeld R, Oliver A, Cantón R.

J Clin Microbiol. 2011 Aug;49(8):2905-10. doi: 10.1128/JCM.00753-11. Epub 2011 Jun 22.


[Tolerance and heteroresistance in Gram-positive microorganisms].

Morosini MI, Cantón R.

Med Clin (Barc). 2010 Dec;135 Suppl 3:16-22. doi: 10.1016/S0025-7753(10)70036-1. Review. Spanish.


Stationary biofilm growth normalizes mutation frequencies and mutant prevention concentrations in Pseudomonas aeruginosa from cystic fibrosis patients.

García-Castillo M, del Campo R, Baquero F, Morosini MI, Turrientes MC, Zamora J, Cantón R.

Clin Microbiol Infect. 2011 May;17(5):704-11. doi: 10.1111/j.1469-0691.2010.03317.x.

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