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Items: 27

1.

Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity.

Horiguchi H, Kadomatsu T, Kurahashi R, Hara C, Miyata K, Baba M, Osumi H, Terada K, Araki K, Takai T, Kamba T, Linehan WM, Moroishi T, Oike Y.

Genes Dev. 2019 Nov 14. doi: 10.1101/gad.329417.119. [Epub ahead of print]

PMID:
31727773
2.

Gold Nanoparticles Coimmobilized with Small Molecule Toll-Like Receptor 7 Ligand and α-Mannose as Adjuvants.

Shinchi H, Yamaguchi T, Moroishi T, Yuki M, Wakao M, Cottam HB, Hayashi T, Carson DA, Suda Y.

Bioconjug Chem. 2019 Nov 20;30(11):2811-2821. doi: 10.1021/acs.bioconjchem.9b00560. Epub 2019 Oct 9.

PMID:
31560198
3.

Hippo Pathway in Mammalian Adaptive Immune System.

Yamauchi T, Moroishi T.

Cells. 2019 Apr 30;8(5). pii: E398. doi: 10.3390/cells8050398. Review.

4.

BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling.

Verma S, Yeddula N, Soda Y, Zhu Q, Pao G, Moresco J, Diedrich JK, Hong A, Plouffe S, Moroishi T, Guan KL, Verma IM.

Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7363-7370. doi: 10.1073/pnas.1822155116. Epub 2019 Mar 27.

5.

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis.

Muto Y, Moroishi T, Ichihara K, Nishiyama M, Shimizu H, Eguchi H, Moriya K, Koike K, Mimori K, Mori M, Katayama Y, Nakayama KI.

J Exp Med. 2019 Apr 1;216(4):950-965. doi: 10.1084/jem.20180900. Epub 2019 Mar 15.

6.

Regulation of mitochondrial iron homeostasis by sideroflexin 2.

Mon EE, Wei FY, Ahmad RNR, Yamamoto T, Moroishi T, Tomizawa K.

J Physiol Sci. 2019 Mar;69(2):359-373. doi: 10.1007/s12576-018-0652-2. Epub 2018 Dec 20.

7.

Cell type-dependent function of LATS1/2 in cancer cell growth.

Pan WW, Moroishi T, Koo JH, Guan KL.

Oncogene. 2019 Apr;38(14):2595-2610. doi: 10.1038/s41388-018-0610-8. Epub 2018 Dec 10.

8.

RAP2 mediates mechanoresponses of the Hippo pathway.

Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL.

Nature. 2018 Aug;560(7720):655-660. doi: 10.1038/s41586-018-0444-0. Epub 2018 Aug 22.

9.

Author Correction: Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation.

Lin KC, Moroishi T, Meng Z, Jeong HS, Plouffe SW, Sekido Y, Han J, Park HW, Guan KL.

Nat Cell Biol. 2018 Sep;20(9):1098. doi: 10.1038/s41556-018-0101-8.

PMID:
30018319
10.

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Martin D, Degese MS, Vitale-Cross L, Iglesias-Bartolome R, Valera JLC, Wang Z, Feng X, Yeerna H, Vadmal V, Moroishi T, Thorne RF, Zaida M, Siegele B, Cheong SC, Molinolo AA, Samuels Y, Tamayo P, Guan KL, Lippman SM, Lyons JG, Gutkind JS.

Nat Commun. 2018 Jul 9;9(1):2372. doi: 10.1038/s41467-018-04590-1.

11.

Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma.

Cosset É, Ilmjärv S, Dutoit V, Elliott K, von Schalscha T, Camargo MF, Reiss A, Moroishi T, Seguin L, Gomez G, Moo JS, Preynat-Seauve O, Krause KH, Chneiweiss H, Sarkaria JN, Guan KL, Dietrich PY, Weis SM, Mischel PS, Cheresh DA.

Cancer Cell. 2017 Dec 11;32(6):856-868.e5. doi: 10.1016/j.ccell.2017.10.016. Epub 2017 Nov 30.

12.

Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation.

Lin KC, Moroishi T, Meng Z, Jeong HS, Plouffe SW, Sekido Y, Han J, Park HW, Guan KL.

Nat Cell Biol. 2017 Jul 28;19(8):996-1002. doi: 10.1038/ncb3581. Erratum in: Nat Cell Biol. 2018 Sep;20(9):1098.

13.

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells.

Muto Y, Nishiyama M, Nita A, Moroishi T, Nakayama KI.

Nat Commun. 2017 Jul 17;8:16114. doi: 10.1038/ncomms16114.

14.

YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.

Taniguchi K, Moroishi T, de Jong PR, Krawczyk M, Grebbin BM, Luo H, Xu RH, Golob-Schwarzl N, Schweiger C, Wang K, Di Caro G, Feng Y, Fearon ER, Raz E, Kenner L, Farin HF, Guan KL, Haybaeck J, Datz C, Zhang K, Karin M.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1643-1648. doi: 10.1073/pnas.1620290114. Epub 2017 Jan 27.

15.

FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.

Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama KI.

Mol Cell Biol. 2017 Mar 31;37(8). pii: e00470-16. doi: 10.1128/MCB.00470-16. Print 2017 Apr 15.

16.

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.

Moroishi T, Hayashi T, Pan WW, Fujita Y, Holt MV, Qin J, Carson DA, Guan KL.

Cell. 2016 Dec 1;167(6):1525-1539.e17. doi: 10.1016/j.cell.2016.11.005.

17.

Glycoholics Anonymous: Cancer Sobers Up with mTORC1.

Fu V, Moroishi T, Guan KL.

Cancer Cell. 2016 Apr 11;29(4):432-434. doi: 10.1016/j.ccell.2016.03.016.

18.

Mechanisms of Hippo pathway regulation.

Meng Z, Moroishi T, Guan KL.

Genes Dev. 2016 Jan 1;30(1):1-17. doi: 10.1101/gad.274027.115. Review.

19.

MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway.

Meng Z, Moroishi T, Mottier-Pavie V, Plouffe SW, Hansen CG, Hong AW, Park HW, Mo JS, Lu W, Lu S, Flores F, Yu FX, Halder G, Guan KL.

Nat Commun. 2015 Oct 5;6:8357. doi: 10.1038/ncomms9357.

20.

Alternative Wnt Signaling Activates YAP/TAZ.

Park HW, Kim YC, Yu B, Moroishi T, Mo JS, Plouffe SW, Meng Z, Lin KC, Yu FX, Alexander CM, Wang CY, Guan KL.

Cell. 2015 Aug 13;162(4):780-94. doi: 10.1016/j.cell.2015.07.013.

21.

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.

Moroishi T, Park HW, Qin B, Chen Q, Meng Z, Plouffe SW, Taniguchi K, Yu FX, Karin M, Pan D, Guan KL.

Genes Dev. 2015 Jun 15;29(12):1271-84. doi: 10.1101/gad.262816.115.

22.

YAP and TAZ: a nexus for Hippo signaling and beyond.

Hansen CG, Moroishi T, Guan KL.

Trends Cell Biol. 2015 Sep;25(9):499-513. doi: 10.1016/j.tcb.2015.05.002. Epub 2015 Jun 2. Review.

23.

The emerging roles of YAP and TAZ in cancer.

Moroishi T, Hansen CG, Guan KL.

Nat Rev Cancer. 2015 Feb;15(2):73-79. doi: 10.1038/nrc3876. Epub 2015 Jan 16. Review.

24.

MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24.

Yamauchi T, Nishiyama M, Moroishi T, Yumimoto K, Nakayama KI.

Mol Cell Biol. 2014 Sep;34(17):3321-40. doi: 10.1128/MCB.00320-14. Epub 2014 Jun 30.

25.

HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism.

Moroishi T, Yamauchi T, Nishiyama M, Nakayama KI.

J Biol Chem. 2014 Jun 6;289(23):16430-41. doi: 10.1074/jbc.M113.541490. Epub 2014 Apr 28.

26.

Comprehensive identification of substrates for F-box proteins by differential proteomics analysis.

Yumimoto K, Matsumoto M, Oyamada K, Moroishi T, Nakayama KI.

J Proteome Res. 2012 Jun 1;11(6):3175-85. doi: 10.1021/pr201216u. Epub 2012 May 1.

PMID:
22524983
27.

The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.

Moroishi T, Nishiyama M, Takeda Y, Iwai K, Nakayama KI.

Cell Metab. 2011 Sep 7;14(3):339-51. doi: 10.1016/j.cmet.2011.07.011.

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