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Items: 1 to 50 of 220

1.

Primed histone demethylation regulates shoot regenerative competency.

Ishihara H, Sugimoto K, Tarr PT, Temman H, Kadokura S, Inui Y, Sakamoto T, Sasaki T, Aida M, Suzuki T, Inagaki S, Morohashi K, Seki M, Kakutani T, Meyerowitz EM, Matsunaga S.

Nat Commun. 2019 Apr 16;10(1):1786. doi: 10.1038/s41467-019-09386-5.

2.

Vitamin B12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection.

Schaffner A, Li X, Gomez-Llorente Y, Leandrou E, Memou A, Clemente N, Yao C, Afsari F, Zhi L, Pan N, Morohashi K, Hua X, Zhou MM, Wang C, Zhang H, Chen SG, Elliott CJ, Rideout H, Ubarretxena-Belandia I, Yue Z.

Cell Res. 2019 Apr;29(4):313-329. doi: 10.1038/s41422-019-0153-8. Epub 2019 Mar 11.

PMID:
30858560
3.

Three populations of adult Leydig cells in mouse testes revealed by a novel mouse HSD3B1-specific rat monoclonal antibody.

Yokoyama C, Chigi Y, Baba T, Ohshitanai A, Harada Y, Takahashi F, Morohashi KI.

Biochem Biophys Res Commun. 2019 Apr 16;511(4):916-920. doi: 10.1016/j.bbrc.2019.02.100. Epub 2019 Mar 7.

PMID:
30851938
4.

Genome-wide analysis of MpBHLH12, a IIIf basic helix-loop-helix transcription factor of Marchantia polymorpha.

Arai H, Yanagiura K, Toyama Y, Morohashi K.

J Plant Res. 2019 Mar;132(2):197-209. doi: 10.1007/s10265-019-01095-w. Epub 2019 Mar 6.

PMID:
30840209
5.

Towards a next step of the research of regulatory networks in plant growth and development.

Morohashi K, Russinova E.

J Plant Res. 2019 Mar;132(2):155-157. doi: 10.1007/s10265-019-01097-8. No abstract available.

PMID:
30825069
6.

Arabidopsis JMJD5/JMJ30 Acts Independently of LUX ARRHYTHMO Within the Plant Circadian Clock to Enable Temperature Compensation.

Jones MA, Morohashi K, Grotewold E, Harmer SL.

Front Plant Sci. 2019 Feb 1;10:57. doi: 10.3389/fpls.2019.00057. eCollection 2019.

7.

Mouse polycomb group gene Cbx2 promotes osteoblastic but suppresses adipogenic differentiation in postnatal long bones.

Katoh-Fukui Y, Baba T, Sato T, Otake H, Nagakui-Noguchi Y, Shindo M, Suyama M, Ohkawa Y, Tsumura H, Morohashi KI, Fukami M.

Bone. 2019 Mar;120:219-231. doi: 10.1016/j.bone.2018.10.021. Epub 2018 Oct 30.

PMID:
30389610
8.

Transcriptome-wide effects of expansin gene manipulation in etiolated Arabidopsis seedling.

Ilias IA, Negishi K, Yasue K, Jomura N, Morohashi K, Baharum SN, Goh HH.

J Plant Res. 2019 Mar;132(2):159-172. doi: 10.1007/s10265-018-1067-0. Epub 2018 Oct 19.

PMID:
30341720
9.

Ad4BP/SF-1 regulates cholesterol synthesis to boost the production of steroids.

Baba T, Otake H, Inoue M, Sato T, Ishihara Y, Moon JY, Tsuchiya M, Miyabayashi K, Ogawa H, Shima Y, Wang L, Sato R, Yamazaki T, Suyama M, Nomura M, Choi MH, Ohkawa Y, Morohashi KI.

Commun Biol. 2018 Mar 22;1:18. doi: 10.1038/s42003-018-0020-z. eCollection 2018.

10.

Adrenocortical development: Lessons from mouse models.

Dumontet T, Sahut-Barnola I, Septier A, Montanier N, Plotton I, Roucher-Boulez F, Ducros V, Lefrançois-Martinez AM, Pointud JC, Zubair M, Morohashi KI, Breault DT, Val P, Martinez A.

Ann Endocrinol (Paris). 2018 Jun;79(3):95-97. doi: 10.1016/j.ando.2018.03.014. Epub 2018 Apr 16.

PMID:
29673697
11.

GTL1 and DF1 regulate root hair growth through transcriptional repression of ROOT HAIR DEFECTIVE 6-LIKE 4 in Arabidopsis.

Shibata M, Breuer C, Kawamura A, Clark NM, Rymen B, Braidwood L, Morohashi K, Busch W, Benfey PN, Sozzani R, Sugimoto K.

Development. 2018 Feb 8;145(3). pii: dev159707. doi: 10.1242/dev.159707.

12.

PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal.

Dumontet T, Sahut-Barnola I, Septier A, Montanier N, Plotton I, Roucher-Boulez F, Ducros V, Lefrançois-Martinez AM, Pointud JC, Zubair M, Morohashi KI, Breault DT, Val P, Martinez A.

JCI Insight. 2018 Jan 25;3(2). pii: 98394. doi: 10.1172/jci.insight.98394. eCollection 2018 Jan 25.

13.

Recent progress in understanding the mechanisms of Leydig cell differentiation.

Inoue M, Baba T, Morohashi KI.

Mol Cell Endocrinol. 2018 Jun 15;468:39-46. doi: 10.1016/j.mce.2017.12.013. Epub 2018 Jan 6. Review.

PMID:
29309805
14.

Dual Roles of Glutathione in Ecdysone Biosynthesis and Antioxidant Function During Larval Development in Drosophila.

Enya S, Yamamoto C, Mizuno H, Esaki T, Lin HK, Iga M, Morohashi K, Hirano Y, Kataoka H, Masujima T, Shimada-Niwa Y, Niwa R.

Genetics. 2017 Dec;207(4):1519-1532. doi: 10.1534/genetics.117.300391. Epub 2017 Oct 11.

15.

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

Xing Y, Morohashi KI, Ingraham HA, Hammer GD.

Development. 2017 Oct 15;144(20):3798-3807. doi: 10.1242/dev.150516. Epub 2017 Sep 11.

16.

A Novel Regulatory Pathway for K+ Uptake in the Legume Symbiont Azorhizobium caulinodans in Which TrkJ Represses the kdpFABC Operon at High Extracellular K+ Concentrations.

Siarot L, Toyazaki H, Hidaka M, Kurumisawa K, Hirakawa T, Morohashi K, Aono T.

Appl Environ Microbiol. 2017 Sep 15;83(19). pii: e01197-17. doi: 10.1128/AEM.01197-17. Print 2017 Oct 1.

17.

Stringent Expression Control of Pathogenic R-body Production in Legume Symbiont Azorhizobium caulinodans.

Matsuoka JI, Ishizuna F, Kurumisawa K, Morohashi K, Ogawa T, Hidaka M, Saito K, Ezawa T, Aono T.

MBio. 2017 Jul 25;8(4). pii: e00715-17. doi: 10.1128/mBio.00715-17.

18.

Gravitropism interferes with hydrotropism via counteracting auxin dynamics in cucumber roots: clinorotation and spaceflight experiments.

Morohashi K, Okamoto M, Yamazaki C, Fujii N, Miyazawa Y, Kamada M, Kasahara H, Osada I, Shimazu T, Fusejima Y, Higashibata A, Yamazaki T, Ishioka N, Kobayashi A, Takahashi H.

New Phytol. 2017 Sep;215(4):1476-1489. doi: 10.1111/nph.14689. Epub 2017 Jul 19.

19.

CBF2A-CBF4B genomic region copy numbers alongside the circadian clock play key regulatory mechanisms driving expression of FR-H2 CBFs.

Dhillon T, Morohashi K, Stockinger EJ.

Plant Mol Biol. 2017 Jun;94(3):333-347. doi: 10.1007/s11103-017-0610-z. Epub 2017 Apr 22.

PMID:
28434151
20.

Corrigendum to "Leydig progenitor cells in fetal testis" [Mol. Cell. Endocrinol. 445 (2017) 55-64].

Shima Y, Morohashi KI.

Mol Cell Endocrinol. 2017 May 15;447:134. doi: 10.1016/j.mce.2017.03.030. No abstract available.

PMID:
28377127
21.

Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth.

Syu JS, Baba T, Huang JY, Ogawa H, Hsieh CH, Hu JX, Chen TY, Lin TC, Tsuchiya M, Morohashi KI, Huang BM, Lu FL, Wang CY.

Sci Rep. 2017 Mar 21;7(1):240. doi: 10.1038/s41598-017-00393-4.

22.

Role of Ad4-binding protein/steroidogenic factor 1 in regulating NADPH production in adrenocortical Y-1 cells.

Li B, Baba T, Miyabayashi K, Sato T, Shima Y, Ichinose T, Miura D, Ohkawa Y, Suyama M, Morohashi KI.

Endocr J. 2017 Mar 31;64(3):315-324. doi: 10.1507/endocrj.EJ16-0467. Epub 2017 Feb 14.

23.

Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells.

Shishido Y, Baba T, Sato T, Shima Y, Miyabayashi K, Inoue M, Akiyama H, Kimura H, Kanai Y, Ishihara Y, Haraguchi S, Miyazaki A, Rozman D, Yamazaki T, Choi MH, Ohkawa Y, Suyama M, Morohashi KI.

Sci Rep. 2017 Feb 2;7:41912. doi: 10.1038/srep41912.

24.

WIND1 Promotes Shoot Regeneration through Transcriptional Activation of ENHANCER OF SHOOT REGENERATION1 in Arabidopsis.

Iwase A, Harashima H, Ikeuchi M, Rymen B, Ohnuma M, Komaki S, Morohashi K, Kurata T, Nakata M, Ohme-Takagi M, Grotewold E, Sugimoto K.

Plant Cell. 2017 Jan;29(1):54-69. doi: 10.1105/tpc.16.00623. Epub 2016 Dec 23.

25.

Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development.

Miyabayashi K, Shima Y, Inoue M, Sato T, Baba T, Ohkawa Y, Suyama M, Morohashi KI.

Sex Dev. 2017;11(2):53-63. doi: 10.1159/000453323. Epub 2016 Dec 14.

26.

Leydig progenitor cells in fetal testis.

Shima Y, Morohashi KI.

Mol Cell Endocrinol. 2017 Apr 15;445:55-64. doi: 10.1016/j.mce.2016.12.006. Epub 2016 Dec 8. Review. Erratum in: Mol Cell Endocrinol. 2017 May 15;447:134.

PMID:
27940302
27.

A Maize Gene Regulatory Network for Phenolic Metabolism.

Yang F, Li W, Jiang N, Yu H, Morohashi K, Ouma WZ, Morales-Mantilla DE, Gomez-Cano FA, Mukundi E, Prada-Salcedo LD, Velazquez RA, Valentin J, Mejía-Guerra MK, Gray J, Doseff AI, Grotewold E.

Mol Plant. 2017 Mar 6;10(3):498-515. doi: 10.1016/j.molp.2016.10.020. Epub 2016 Nov 19.

28.

SF-1 deficiency causes lipid accumulation in Leydig cells via suppression of STAR and CYP11A1.

Hatano M, Migita T, Ohishi T, Shima Y, Ogawa Y, Morohashi KI, Hasegawa Y, Shibasaki F.

Endocrine. 2016 Nov;54(2):484-496. Epub 2016 Jul 25.

PMID:
27455990
29.

Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice.

Umehara T, Kawashima I, Kawai T, Hoshino Y, Morohashi KI, Shima Y, Zeng W, Richards JS, Shimada M.

Endocrinology. 2016 Dec;157(12):4899-4913. Epub 2016 Oct 12.

30.

Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues.

Igarashi M, Takasawa K, Hakoda A, Kanno J, Takada S, Miyado M, Baba T, Morohashi KI, Tajima T, Hata K, Nakabayashi K, Matsubara Y, Sekido R, Ogata T, Kashimada K, Fukami M.

Hum Mutat. 2017 Jan;38(1):39-42. doi: 10.1002/humu.23116. Epub 2016 Sep 21.

PMID:
27610946
31.

Testicular dysgenesis/regression without campomelic dysplasia in patients carrying missense mutations and upstream deletion of SOX9.

Katoh-Fukui Y, Igarashi M, Nagasaki K, Horikawa R, Nagai T, Tsuchiya T, Suzuki E, Miyado M, Hata K, Nakabayashi K, Hayashi K, Matsubara Y, Baba T, Morohashi K, Igarashi A, Ogata T, Takada S, Fukami M.

Mol Genet Genomic Med. 2015 Jul 14;3(6):550-7. doi: 10.1002/mgg3.165. eCollection 2015 Nov.

32.

Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice.

Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K.

Endocrinology. 2016 Mar;157(3):1222-33. doi: 10.1210/en.2015-1773. Epub 2015 Dec 23.

PMID:
26697723
33.

Selective autophagic receptor p62 regulates the abundance of transcriptional coregulator ARIP4 during nutrient starvation.

Tsuchiya M, Isogai S, Taniguchi H, Tochio H, Shirakawa M, Morohashi KI, Hiraoka Y, Haraguchi T, Ogawa H.

Sci Rep. 2015 Sep 28;5:14498. doi: 10.1038/srep14498.

34.

Fetal Leydig Cells Persist as an Androgen-Independent Subpopulation in the Postnatal Testis.

Shima Y, Matsuzaki S, Miyabayashi K, Otake H, Baba T, Kato S, Huhtaniemi I, Morohashi K.

Mol Endocrinol. 2015 Nov;29(11):1581-93. doi: 10.1210/me.2015-1200. Epub 2015 Sep 24.

35.

Ridaifen G, tamoxifen analog, is a potent anticancer drug working through a combinatorial association with multiple cellular factors.

Ikeda K, Kamisuki S, Uetake S, Mizusawa A, Ota N, Sasaki T, Tsukuda S, Kusayanagi T, Takakusagi Y, Morohashi K, Yamori T, Dan S, Shiina I, Sugawara F.

Bioorg Med Chem. 2015 Sep 15;23(18):6118-24. doi: 10.1016/j.bmc.2015.08.001. Epub 2015 Aug 5.

PMID:
26314924
36.

A practical fluorogenic substrate for high-throughput screening of glutathione S-transferase inhibitors.

Fujikawa Y, Morisaki F, Ogura A, Morohashi K, Enya S, Niwa R, Goto S, Kojima H, Okabe T, Nagano T, Inoue H.

Chem Commun (Camb). 2015 Jul 21;51(57):11459-62. doi: 10.1039/c5cc02067k.

PMID:
26090533
37.

Heterogeneity of ovarian theca and interstitial gland cells in mice.

Miyabayashi K, Tokunaga K, Otake H, Baba T, Shima Y, Morohashi K.

PLoS One. 2015 Jun 3;10(6):e0128352. doi: 10.1371/journal.pone.0128352. eCollection 2015.

38.

Epidermis-dermis junction as a novel location for bone marrow-derived cells to reside in response to ionizing radiation.

Okano J, Kojima H, Katagi M, Nakae Y, Terashima T, Nakagawa T, Kurakane T, Okamoto N, Morohashi K, Maegawa H, Udagawa J.

Biochem Biophys Res Commun. 2015 Jun 12;461(4):695-701. doi: 10.1016/j.bbrc.2015.04.094. Epub 2015 Apr 25.

PMID:
25922286
39.

[Regulation of metabolism by orphan receptor regulone].

Morohashi K, Baba T.

Seikagaku. 2014 Dec;86(6):719-25. Review. Japanese. No abstract available.

PMID:
25675809
40.

Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain.

Ren C, Morohashi K, Plotnikov AN, Jakoncic J, Smith SG, Li J, Zeng L, Rodriguez Y, Stojanoff V, Walsh M, Zhou MM.

Chem Biol. 2015 Feb 19;22(2):161-8. doi: 10.1016/j.chembiol.2014.11.021. Epub 2015 Feb 5.

41.

ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence.

Chung D, Barker BM, Carey CC, Merriman B, Werner ER, Lechner BE, Dhingra S, Cheng C, Xu W, Blosser SJ, Morohashi K, Mazurie A, Mitchell TK, Haas H, Mitchell AP, Cramer RA.

PLoS Pathog. 2014 Nov 6;10(11):e1004487. doi: 10.1371/journal.ppat.1004487. eCollection 2014 Nov. Erratum in: PLoS Pathog. 2014 Nov;10(11):e1004576.

42.

Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex.

Yokoyama A, Igarashi K, Sato T, Takagi K, Otsuka I M, Shishido Y, Baba T, Ito R, Kanno J, Ohkawa Y, Morohashi K, Sugawara A.

J Biol Chem. 2014 Jun 27;289(26):18152-62. doi: 10.1074/jbc.M114.566448. Epub 2014 May 14.

43.

Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1.

Baba T, Otake H, Sato T, Miyabayashi K, Shishido Y, Wang CY, Shima Y, Kimura H, Yagi M, Ishihara Y, Hino S, Ogawa H, Nakao M, Yamazaki T, Kang D, Ohkawa Y, Suyama M, Chung BC, Morohashi K.

Nat Commun. 2014 Apr 14;5:3634. doi: 10.1038/ncomms4634.

PMID:
24727981
44.

Helix-loop-helix/basic helix-loop-helix transcription factor network represses cell elongation in Arabidopsis through an apparent incoherent feed-forward loop.

Zhiponova MK, Morohashi K, Vanhoutte I, Machemer-Noonan K, Revalska M, Van Montagu M, Grotewold E, Russinova E.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2824-9. doi: 10.1073/pnas.1400203111. Epub 2014 Feb 6.

45.

Novel class of potential therapeutics that target ricin retrograde translocation.

Redmann V, Gardner T, Lau Z, Morohashi K, Felsenfeld D, Tortorella D.

Toxins (Basel). 2013 Dec 23;6(1):33-53. doi: 10.3390/toxins6010033.

46.

Regulatory modules controlling maize inflorescence architecture.

Eveland AL, Goldshmidt A, Pautler M, Morohashi K, Liseron-Monfils C, Lewis MW, Kumari S, Hiraga S, Yang F, Unger-Wallace E, Olson A, Hake S, Vollbrecht E, Grotewold E, Ware D, Jackson D.

Genome Res. 2014 Mar;24(3):431-43. doi: 10.1101/gr.166397.113. Epub 2013 Dec 4.

47.

Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains.

Zhang G, Plotnikov AN, Rusinova E, Shen T, Morohashi K, Joshua J, Zeng L, Mujtaba S, Ohlmeyer M, Zhou MM.

J Med Chem. 2013 Nov 27;56(22):9251-64. doi: 10.1021/jm401334s. Epub 2013 Nov 11.

48.

Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development.

Fujimoto Y, Tanaka SS, Yamaguchi YL, Kobayashi H, Kuroki S, Tachibana M, Shinomura M, Kanai Y, Morohashi K, Kawakami K, Nishinakamura R.

Dev Cell. 2013 Aug 26;26(4):416-30. doi: 10.1016/j.devcel.2013.06.018.

49.

Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells.

Miyabayashi K, Katoh-Fukui Y, Ogawa H, Baba T, Shima Y, Sugiyama N, Kitamura K, Morohashi K.

PLoS One. 2013 Jun 28;8(6):e68050. doi: 10.1371/journal.pone.0068050. Print 2013.

50.

Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets.

Arango D, Morohashi K, Yilmaz A, Kuramochi K, Parihar A, Brahimaj B, Grotewold E, Doseff AI.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):E2153-62. doi: 10.1073/pnas.1303726110. Epub 2013 May 22.

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