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Items: 1 to 50 of 168

1.

Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance.

Peña-Martínez C, Durán-Laforet V, García-Culebras A, Ostos F, Hernández-Jiménez M, Bravo-Ferrer I, Pérez-Ruiz A, Ballenilla F, Díaz-Guzmán J, Pradillo JM, Lizasoain I, Moro MA.

Stroke. 2019 Nov;50(11):3228-3237. doi: 10.1161/STROKEAHA.119.026848. Epub 2019 Sep 17.

PMID:
31526124
2.

Lack of the aryl hydrocarbon receptor accelerates aging in mice.

Bravo-Ferrer I, Cuartero MI, Medina V, Ahedo-Quero D, Peña-Martínez C, Pérez-Ruíz A, Fernández-Valle ME, Hernández-Sánchez C, Fernández-Salguero PM, Lizasoain I, Moro MA.

FASEB J. 2019 Nov;33(11):12644-12654. doi: 10.1096/fj.201901333R. Epub 2019 Sep 4.

PMID:
31483997
3.

Role of TLR4 (Toll-Like Receptor 4) in N1/N2 Neutrophil Programming After Stroke.

García-Culebras A, Durán-Laforet V, Peña-Martínez C, Moraga A, Ballesteros I, Cuartero MI, de la Parra J, Palma-Tortosa S, Hidalgo A, Corbí AL, Moro MA, Lizasoain I.

Stroke. 2019 Oct;50(10):2922-2932. doi: 10.1161/STROKEAHA.119.025085. Epub 2019 Aug 27.

PMID:
31451099
4.

Delayed Effects of Acute Reperfusion on Vascular Remodeling and Late-Phase Functional Recovery After Stroke.

Durán-Laforet V, Fernández-López D, García-Culebras A, González-Hijón J, Moraga A, Palma-Tortosa S, García-Yébenes I, Vega-Pérez A, Lizasoain I, Moro MÁ.

Front Neurosci. 2019 Jul 23;13:767. doi: 10.3389/fnins.2019.00767. eCollection 2019.

5.

Toll-like receptor 4 regulates subventricular zone proliferation and neuroblast migration after experimental stroke.

Palma-Tortosa S, Hurtado O, Pradillo JM, Ferreras-Martín R, García-Yébenes I, García-Culebras A, Moraga A, Moro MÁ, Lizasoain I.

Brain Behav Immun. 2019 Aug;80:573-582. doi: 10.1016/j.bbi.2019.05.002. Epub 2019 May 3.

PMID:
31059808
6.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A.

Immunity. 2019 Feb 19;50(2):390-402.e10. doi: 10.1016/j.immuni.2019.01.002. Epub 2019 Jan 29.

PMID:
30709741
7.

Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice.

Cuartero MI, de la Parra J, Pérez-Ruiz A, Bravo-Ferrer I, Durán-Laforet V, García-Culebras A, García-Segura JM, Dhaliwal J, Frankland PW, Lizasoain I, Moro MÁ.

J Clin Invest. 2019 Apr 1;129(4):1536-1550. doi: 10.1172/JCI120412. Epub 2019 Feb 25.

8.

AhR Deletion Promotes Aberrant Morphogenesis and Synaptic Activity of Adult-Generated Granule Neurons and Impairs Hippocampus-Dependent Memory.

de la Parra J, Cuartero MI, Pérez-Ruiz A, García-Culebras A, Martín R, Sánchez-Prieto J, García-Segura JM, Lizasoain I, Moro MA.

eNeuro. 2018 Aug 22;5(4). pii: ENEURO.0370-17.2018. doi: 10.1523/ENEURO.0370-17.2018. eCollection 2018 Jul-Aug.

9.

Myeloid cells as therapeutic targets in neuroinflammation after stroke: Specific roles of neutrophils and neutrophil-platelet interactions.

García-Culebras A, Durán-Laforet V, Peña-Martínez C, Ballesteros I, Pradillo JM, Díaz-Guzmán J, Lizasoain I, Moro MA.

J Cereb Blood Flow Metab. 2018 Dec;38(12):2150-2164. doi: 10.1177/0271678X18795789. Epub 2018 Aug 21. Review.

PMID:
30129391
10.

Iron Overload Exacerbates the Risk of Hemorrhagic Transformation After tPA (Tissue-Type Plasminogen Activator) Administration in Thromboembolic Stroke Mice.

García-Yébenes I, García-Culebras A, Peña-Martínez C, Fernández-López D, Díaz-Guzmán J, Negredo P, Avendaño C, Castellanos M, Gasull T, Dávalos A, Moro MA, Lizasoain I.

Stroke. 2018 Sep;49(9):2163-2172. doi: 10.1161/STROKEAHA.118.021540.

PMID:
30018160
11.

TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models.

Fernández G, Moraga A, Cuartero MI, García-Culebras A, Peña-Martínez C, Pradillo JM, Hernández-Jiménez M, Sacristán S, Ayuso MI, Gonzalo-Gobernado R, Fernández-López D, Martín ME, Moro MA, González VM, Lizasoain I.

Mol Ther. 2018 Aug 1;26(8):2047-2059. doi: 10.1016/j.ymthe.2018.05.019. Epub 2018 Jun 15.

12.

Specific Features of SVZ Neurogenesis After Cortical Ischemia: a Longitudinal Study.

Palma-Tortosa S, García-Culebras A, Moraga A, Hurtado O, Perez-Ruiz A, Durán-Laforet V, Parra J, Cuartero MI, Pradillo JM, Moro MA, Lizasoain I.

Sci Rep. 2017 Nov 27;7(1):16343. doi: 10.1038/s41598-017-16109-7.

13.

Test repositioning for functional assessment of neurological outcome after experimental stroke in mice.

Hernández-Jiménez M, Peña-Martínez C, Godino MDC, Díaz-Guzmán J, Moro MÁ, Lizasoain I.

PLoS One. 2017 May 4;12(5):e0176770. doi: 10.1371/journal.pone.0176770. eCollection 2017.

14.

Toll-Like Receptor 4 Mediates Hemorrhagic Transformation After Delayed Tissue Plasminogen Activator Administration in In Situ Thromboembolic Stroke.

García-Culebras A, Palma-Tortosa S, Moraga A, García-Yébenes I, Durán-Laforet V, Cuartero MI, de la Parra J, Barrios-Muñoz AL, Díaz-Guzmán J, Pradillo JM, Moro MA, Lizasoain I.

Stroke. 2017 Jun;48(6):1695-1699. doi: 10.1161/STROKEAHA.116.015956. Epub 2017 Apr 20.

PMID:
28428349
15.

Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke.

Bravo-Ferrer I, Cuartero MI, Zarruk JG, Pradillo JM, Hurtado O, Romera VG, Díaz-Alonso J, García-Segura JM, Guzmán M, Lizasoain I, Galve-Roperh I, Moro MA.

Stroke. 2017 Jan;48(1):204-212. doi: 10.1161/STROKEAHA.116.014793. Epub 2016 Nov 29.

PMID:
27899748
16.

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia.

Pradillo JM, Murray KN, Coutts GA, Moraga A, Oroz-Gonjar F, Boutin H, Moro MA, Lizasoain I, Rothwell NJ, Allan SM.

Brain Behav Immun. 2017 Mar;61:117-126. doi: 10.1016/j.bbi.2016.11.013. Epub 2016 Nov 14.

17.

Imaging the role of toll-like receptor 4 on cell proliferation and inflammation after cerebral ischemia by positron emission tomography.

Moraga A, Gómez-Vallejo V, Cuartero MI, Szczupak B, San Sebastián E, Markuerkiaga I, Pradillo JM, Higuchi M, Llop J, Moro MÁ, Martín A, Lizasoain I.

J Cereb Blood Flow Metab. 2016 Apr;36(4):702-8. doi: 10.1177/0271678X15627657. Epub 2016 Jan 19.

18.

Seladin-1/DHCR24 Is Neuroprotective by Associating EAAT2 Glutamate Transporter to Lipid Rafts in Experimental Stroke.

Hernández-Jiménez M, Martínez-López D, Gabandé-Rodríguez E, Martín-Segura A, Lizasoain I, Ledesma MD, Dotti CG, Moro MA.

Stroke. 2016 Jan;47(1):206-13. doi: 10.1161/STROKEAHA.115.010810. Epub 2015 Dec 1.

PMID:
26628388
19.

Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications.

Fernández-Ruiz J, Moro MA, Martínez-Orgado J.

Neurotherapeutics. 2015 Oct;12(4):793-806. doi: 10.1007/s13311-015-0381-7. Review.

20.

Rational modulation of the innate immune system for neuroprotection in ischemic stroke.

Amantea D, Micieli G, Tassorelli C, Cuartero MI, Ballesteros I, Certo M, Moro MA, Lizasoain I, Bagetta G.

Front Neurosci. 2015 Apr 29;9:147. doi: 10.3389/fnins.2015.00147. eCollection 2015. Review.

21.

Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia.

Moraga A, Pradillo JM, García-Culebras A, Palma-Tortosa S, Ballesteros I, Hernández-Jiménez M, Moro MA, Lizasoain I.

J Neuroinflammation. 2015 May 10;12:87. doi: 10.1186/s12974-015-0314-8.

22.

Complexity of the cell-cell interactions in the innate immune response after cerebral ischemia.

Cuartero MI, Ballesteros I, Lizasoain I, Moro MA.

Brain Res. 2015 Oct 14;1623:53-62. doi: 10.1016/j.brainres.2015.04.047. Epub 2015 May 5.

PMID:
25956207
23.

Stereological and flow cytometry characterization of leukocyte subpopulations in models of transient or permanent cerebral ischemia.

Ballesteros I, Cuartero MI, Moraga A, de la Parra J, Lizasoain I, Moro MÁ.

J Vis Exp. 2014 Dec 28;(94). doi: 10.3791/52031.

24.

Neutrophils scan for activated platelets to initiate inflammation.

Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nácher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi MD, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A.

Science. 2014 Dec 5;346(6214):1234-8. doi: 10.1126/science.1256478. Epub 2014 Dec 4.

25.

L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke.

Cuartero MI, Ballesteros I, de la Parra J, Harkin AL, Abautret-Daly A, Sherwin E, Fernández-Salguero P, Corbí AL, Lizasoain I, Moro MA.

Circulation. 2014 Dec 2;130(23):2040-51. doi: 10.1161/CIRCULATIONAHA.114.011394. Epub 2014 Oct 30.

PMID:
25359166
26.

Intravenous immunoglobulin promotes antitumor responses by modulating macrophage polarization.

Domínguez-Soto A, de las Casas-Engel M, Bragado R, Medina-Echeverz J, Aragoneses-Fenoll L, Martín-Gayo E, van Rooijen N, Berraondo P, Toribio ML, Moro MA, Cuartero I, Castrillo A, Sancho D, Sánchez-Torres C, Bruhns P, Sánchez-Ramón S, Corbí AL.

J Immunol. 2014 Nov 15;193(10):5181-9. doi: 10.4049/jimmunol.1303375. Epub 2014 Oct 17.

27.

The Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia.

Cuartero MI, de la Parra J, García-Culebras A, Ballesteros I, Lizasoain I, Moro MÁ.

Curr Pharm Des. 2016;22(8):1060-73. Review.

28.

Pallister-Killian syndrome in a preterm newborn who died soon after precipitous delivery: cytogenetic analysis.

Moro MA, Sanna R, Cambosu F, Soro G, Dessole S, Montella A, Capobianco G.

Clin Exp Obstet Gynecol. 2014;41(4):483-5.

PMID:
25134307
29.

Toll-like receptor 4 modulates cell migration and cortical neurogenesis after focal cerebral ischemia.

Moraga A, Pradillo JM, Cuartero MI, Hernández-Jiménez M, Oses M, Moro MA, Lizasoain I.

FASEB J. 2014 Nov;28(11):4710-8. doi: 10.1096/fj.14-252452. Epub 2014 Jul 25.

PMID:
25063846
30.

The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins.

Camós S, Gubern C, Sobrado M, Rodríguez R, Romera VG, Moro MA, Lizasoain I, Serena J, Mallolas J, Castellanos M.

Neuroscience. 2014 Jun 6;269:112-30. doi: 10.1016/j.neuroscience.2014.03.036. Epub 2014 Mar 27.

PMID:
24680881
31.

Characterization of Gcf2/Lrrfip1 in experimental cerebral ischemia and its role as a modulator of Akt, mTOR and β-catenin signaling pathways.

Gubern C, Camós S, Hurtado O, Rodríguez R, Romera VG, Sobrado M, Cañadas R, Moro MA, Lizasoain I, Serena J, Mallolas J, Castellanos M.

Neuroscience. 2014 May 30;268:48-65. doi: 10.1016/j.neuroscience.2014.02.051. Epub 2014 Mar 14.

PMID:
24637094
32.

Prenatal diagnosis and molecular cytogenetic characterisation of a de novo 18p deletion.

Fogu G, Capobianco G, Cambosu F, Bandiera P, Pirino A, Moro MA, Campus PM, Soro G, Dessole M, Montella A.

J Obstet Gynaecol. 2014 Feb;34(2):192-3. doi: 10.3109/01443615.2013.834300. No abstract available.

PMID:
24456448
33.

Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways.

Ballesteros I, Cuartero MI, Pradillo JM, de la Parra J, Pérez-Ruiz A, Corbí A, Ricote M, Hamilton JA, Sobrado M, Vivancos J, Nombela F, Lizasoain I, Moro MA.

J Leukoc Biol. 2014 Apr;95(4):587-98. doi: 10.1189/jlb.0613326. Epub 2013 Dec 12.

PMID:
24338629
34.

Oct-2 transcription factor binding activity and expression up-regulation in rat cerebral ischaemia is associated with a diminution of neuronal damage in vitro.

Camós S, Gubern C, Sobrado M, Rodríguez R, Romera VG, Moro MÁ, Lizasoain I, Serena J, Mallolas J, Castellanos M.

Neuromolecular Med. 2014 Jun;16(2):332-49. doi: 10.1007/s12017-013-8279-1. Epub 2013 Nov 27.

PMID:
24282026
35.

N2 neutrophils, novel players in brain inflammation after stroke: modulation by the PPARγ agonist rosiglitazone.

Cuartero MI, Ballesteros I, Moraga A, Nombela F, Vivancos J, Hamilton JA, Corbí ÁL, Lizasoain I, Moro MA.

Stroke. 2013 Dec;44(12):3498-508. doi: 10.1161/STROKEAHA.113.002470. Epub 2013 Oct 17.

PMID:
24135932
36.

miRNA expression is modulated over time after focal ischaemia: up-regulation of miR-347 promotes neuronal apoptosis.

Gubern C, Camós S, Ballesteros I, Rodríguez R, Romera VG, Cañadas R, Lizasoain I, Moro MA, Serena J, Mallolas J, Castellanos M.

FEBS J. 2013 Dec;280(23):6233-46. doi: 10.1111/febs.12546. Epub 2013 Oct 28.

37.

Amelioration of ischemic brain damage by peritoneal dialysis.

Godino Mdel C, Romera VG, Sánchez-Tomero JA, Pacheco J, Canals S, Lerma J, Vivancos J, Moro MA, Torres M, Lizasoain I, Sánchez-Prieto J.

J Clin Invest. 2013 Oct;123(10):4359-63. doi: 10.1172/JCI67284. Epub 2013 Sep 3.

38.

Silent information regulator 1 protects the brain against cerebral ischemic damage.

Hernández-Jiménez M, Hurtado O, Cuartero MI, Ballesteros I, Moraga A, Pradillo JM, McBurney MW, Lizasoain I, Moro MA.

Stroke. 2013 Aug;44(8):2333-7. doi: 10.1161/STROKEAHA.113.001715. Epub 2013 May 30.

PMID:
23723308
39.

Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke.

Hurtado O, Hernández-Jiménez M, Zarruk JG, Cuartero MI, Ballesteros I, Camarero G, Moraga A, Pradillo JM, Moro MA, Lizasoain I.

J Neurochem. 2013 Sep;126(6):819-26. doi: 10.1111/jnc.12269. Epub 2013 May 13.

40.

Neuronal excitotoxicity after carotid angioplasty and stent placement procedures.

Nombela F, Blanco M, Pérez de la Ossa N, Caniego JL, Sobrino T, Escudero D, Campos F, Moro MÁ, Lizasoaín I, Dávalos A, Castillo J, Vivancos J.

Radiology. 2013 Aug;268(2):515-20. doi: 10.1148/radiol.13112104. Epub 2013 Mar 22.

PMID:
23525205
41.

Cannabinoids: well-suited candidates for the treatment of perinatal brain injury.

Fernández-López D, Lizasoain I, Moro MA, Martínez-Orgado J.

Brain Sci. 2013 Jul 10;3(3):1043-59. doi: 10.3390/brainsci3031043.

42.

Iron overload, measured as serum ferritin, increases brain damage induced by focal ischemia and early reperfusion.

García-Yébenes I, Sobrado M, Moraga A, Zarruk JG, Romera VG, Pradillo JM, Perez de la Ossa N, Moro MA, Dávalos A, Lizasoain I.

Neurochem Int. 2012 Dec;61(8):1364-9. doi: 10.1016/j.neuint.2012.09.014. Epub 2012 Oct 2.

PMID:
23036361
43.

Partial trisomy of the long arm of chromosome 1: prenatal diagnosis, clinical evaluation and cytogenetic findings. Case report and review of the literature.

Cambosu F, Capobianco G, Fogu G, Bandiera P, Pirino A, Moro MA, Sanna R, Soro G, Dessole M, Montella A.

J Obstet Gynaecol Res. 2013 Feb;39(2):592-7. doi: 10.1111/j.1447-0756.2012.01986.x. Epub 2012 Aug 26. Review.

PMID:
22925348
44.

Unbalanced 1q whole-arm translocation resulting in der(14)t(1;14)(q11-12;p11) in myelodysplastic syndrome.

Fogu G, Campus PM, Cambosu F, Moro MA, Sanna R, Fozza C, Nieddu RM, Longinotti M, Montella A.

Cytogenet Genome Res. 2012;136(4):256-63. doi: 10.1159/000338437. Epub 2012 May 10. Review.

45.

Daidzein has neuroprotective effects through ligand-binding-independent PPARγ activation.

Hurtado O, Ballesteros I, Cuartero MI, Moraga A, Pradillo JM, Ramírez-Franco J, Bartolomé-Martín D, Pascual D, Torres M, Sánchez-Prieto J, Salom JB, Lizasoain I, Moro MA.

Neurochem Int. 2012 Jul;61(1):119-27. doi: 10.1016/j.neuint.2012.04.007. Epub 2012 Apr 11.

PMID:
22521773
46.

Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome: is PTPN22 involved?

Colina M, Pippucci T, Moro MA, Marconi C, Magini P, Ciancio G, Romeo G, Trotta F, Seri M.

Clin Exp Rheumatol. 2012 May-Jun;30(3):451. Epub 2012 Jun 26. No abstract available.

PMID:
22513164
47.

Regulator of calcineurin 1 (Rcan1) has a protective role in brain ischemia/reperfusion injury.

Sobrado M, Ramirez BG, Neria F, Lizasoain I, Arbones ML, Minami T, Redondo JM, Moro MA, Cano E.

J Neuroinflammation. 2012 Mar 7;9:48. doi: 10.1186/1742-2094-9-48.

48.

Reduced infarct size and accumulation of microglia in rats treated with WIN 55,212-2 after neonatal stroke.

Fernández-López D, Faustino J, Derugin N, Wendland M, Lizasoain I, Moro MA, Vexler ZS.

Neuroscience. 2012 Apr 5;207:307-15. doi: 10.1016/j.neuroscience.2012.01.008. Epub 2012 Jan 12.

49.

Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.

Redondo M, Zarruk JG, Ceballos P, Pérez DI, Pérez C, Perez-Castillo A, Moro MA, Brea J, Val C, Cadavid MI, Loza MI, Campillo NE, Martínez A, Gil C.

Eur J Med Chem. 2012 Jan;47(1):175-85. doi: 10.1016/j.ejmech.2011.10.040. Epub 2011 Nov 4.

PMID:
22100138
50.

Neurological tests for functional outcome assessment in rodent models of ischaemic stroke.

Zarruk JG, Garcia-Yebenes I, Romera VG, Ballesteros I, Moraga A, Cuartero MI, Hurtado O, Sobrado M, Pradillo JM, Fernandez-Lopez D, Serena J, Castillo-Melendez M, Moro MA, Lizasoain I.

Rev Neurol. 2011 Nov 16;53(10):607-18. English, Spanish.

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