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Items: 36


Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors.

Felix J, Weinhäupl K, Chipot C, Dehez F, Hessel A, Gauto DF, Morlot C, Abian O, Gutsche I, Velazquez-Campoy A, Schanda P, Fraga H.

Sci Adv. 2019 Sep 4;5(9):eaaw3818. doi: 10.1126/sciadv.aaw3818. eCollection 2019 Sep.


Origin of a Core Bacterial Gene via Co-option and Detoxification of a Phage Lysin.

Randich AM, Kysela DT, Morlot C, Brun YV.

Curr Biol. 2019 May 20;29(10):1634-1646.e6. doi: 10.1016/j.cub.2019.04.032. Epub 2019 May 9.


Structural characterization of the sporulation protein GerM from Bacillus subtilis.

Trouve J, Mohamed A, Leisico F, Contreras-Martel C, Liu B, Mas C, Rudner DZ, Rodrigues CDA, Morlot C.

J Struct Biol. 2018 Dec;204(3):481-490. doi: 10.1016/j.jsb.2018.09.010. Epub 2018 Sep 25.


Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.

Morlot C, Straume D, Peters K, Hegnar OA, Simon N, Villard AM, Contreras-Martel C, Leisico F, Breukink E, Gravier-Pelletier C, Le Corre L, Vollmer W, Pietrancosta N, Håvarstein LS, Zapun A.

Nat Commun. 2018 Aug 9;9(1):3180. doi: 10.1038/s41467-018-05602-w.


The cell wall hydrolase Pmp23 is important for assembly and stability of the division ring in Streptococcus pneumoniae.

Jacq M, Arthaud C, Manuse S, Mercy C, Bellard L, Peters K, Gallet B, Galindo J, Doan T, Vollmer W, Brun YV, VanNieuwenhze MS, Di Guilmi AM, Vernet T, Grangeasse C, Morlot C.

Sci Rep. 2018 May 15;8(1):7591. doi: 10.1038/s41598-018-25882-y.


The New Kid on the Block: A Specialized Secretion System during Bacterial Sporulation.

Morlot C, Rodrigues CDA.

Trends Microbiol. 2018 Aug;26(8):663-676. doi: 10.1016/j.tim.2018.01.001. Epub 2018 Feb 20. Review.


Peptidoglycan O-acetylation is functionally related to cell wall biosynthesis and cell division in Streptococcus pneumoniae.

Bonnet J, Durmort C, Jacq M, Mortier-Barrière I, Campo N, VanNieuwenhze MS, Brun YV, Arthaud C, Gallet B, Moriscot C, Morlot C, Vernet T, Di Guilmi AM.

Mol Microbiol. 2017 Dec;106(5):832-846. doi: 10.1111/mmi.13849. Epub 2017 Oct 26.


Autocatalytic association of proteins by covalent bond formation: a Bio Molecular Welding toolbox derived from a bacterial adhesin.

Bonnet J, Cartannaz J, Tourcier G, Contreras-Martel C, Kleman JP, Morlot C, Vernet T, Di Guilmi AM.

Sci Rep. 2017 Mar 2;7:43564. doi: 10.1038/srep43564.


Identification, distribution, and quantification of biominerals in a deciduous forest.

Krieger C, Calvaruso C, Morlot C, Uroz S, Salsi L, Turpault MP.

Geobiology. 2017 Mar;15(2):296-310. doi: 10.1111/gbi.12223. Epub 2017 Jan 28.


Enterococcus hirae LcpA (Psr), a new peptidoglycan-binding protein localized at the division site.

Maréchal M, Amoroso A, Morlot C, Vernet T, Coyette J, Joris B.

BMC Microbiol. 2016 Oct 12;16(1):239.


Resistance to β-Lactams in Neisseria ssp Due to Chromosomally Encoded Penicillin-Binding Proteins.

Zapun A, Morlot C, Taha MK.

Antibiotics (Basel). 2016 Sep 28;5(4). pii: E35. Review.


A ring-shaped conduit connects the mother cell and forespore during sporulation in Bacillus subtilis.

Rodrigues CD, Henry X, Neumann E, Kurauskas V, Bellard L, Fichou Y, Schanda P, Schoehn G, Rudner DZ, Morlot C.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11585-11590. Epub 2016 Sep 28.


Autophosphorylation of the Bacterial Tyrosine-Kinase CpsD Connects Capsule Synthesis with the Cell Cycle in Streptococcus pneumoniae.

Nourikyan J, Kjos M, Mercy C, Cluzel C, Morlot C, Noirot-Gros MF, Guiral S, Lavergne JP, Veening JW, Grangeasse C.

PLoS Genet. 2015 Sep 17;11(9):e1005518. doi: 10.1371/journal.pgen.1005518. eCollection 2015 Sep.


Remodeling of the Z-Ring Nanostructure during the Streptococcus pneumoniae Cell Cycle Revealed by Photoactivated Localization Microscopy.

Jacq M, Adam V, Bourgeois D, Moriscot C, Di Guilmi AM, Vernet T, Morlot C.

mBio. 2015 Aug 18;6(4). pii: e01108-15. doi: 10.1128/mBio.01108-15.


Full-length structure of the major autolysin LytA.

Li Q, Cheng W, Morlot C, Bai XH, Jiang YL, Wang W, Roper DI, Vernet T, Dong YH, Chen Y, Zhou CZ.

Acta Crystallogr D Biol Crystallogr. 2015 Jun;71(Pt 6):1373-81. doi: 10.1107/S1399004715007403. Epub 2015 May 23.


Mechanism of β-lactam action in Streptococcus pneumoniae: the piperacillin paradox.

Philippe J, Gallet B, Morlot C, Denapaite D, Hakenbeck R, Chen Y, Vernet T, Zapun A.

Antimicrob Agents Chemother. 2015 Jan;59(1):609-21. doi: 10.1128/AAC.04283-14. Epub 2014 Nov 10.


Construction of standardized surveillance indicators for bovine cysticercosis.

Dupuy C, Morlot C, Demont P, Ducrot C, Calavas D, Callait-Cardinal MP, Gay E.

Prev Vet Med. 2014 Aug 1;115(3-4):288-92. doi: 10.1016/j.prevetmed.2014.03.024. Epub 2014 Apr 3.


Prevalence of Taenia saginata cysticercosis in French cattle in 2010.

Dupuy C, Morlot C, Gilot-Fromont E, Mas M, Grandmontagne C, Gilli-Dunoyer P, Gay E, Callait-Cardinal MP.

Vet Parasitol. 2014 Jun 16;203(1-2):65-72. doi: 10.1016/j.vetpar.2014.02.054. Epub 2014 Mar 5.


Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein.

Duan C, Adam V, Byrdin M, Ridard J, Kieffer-Jaquinod S, Morlot C, Arcizet D, Demachy I, Bourgeois D.

J Am Chem Soc. 2013 Oct 23;135(42):15841-50. doi: 10.1021/ja406860e. Epub 2013 Oct 7.


Interaction of Penicillin-Binding Protein 2x and Ser/Thr protein kinase StkP, two key players in Streptococcus pneumoniae R6 morphogenesis.

Morlot C, Bayle L, Jacq M, Fleurie A, Tourcier G, Galisson F, Vernet T, Grangeasse C, Di Guilmi AM.

Mol Microbiol. 2013 Oct;90(1):88-102. doi: 10.1111/mmi.12348. Epub 2013 Aug 27.


Structure-function analysis of the LytM domain of EnvC, an activator of cell wall remodelling at the Escherichia coli division site.

Peters NT, Morlot C, Yang DC, Uehara T, Vernet T, Bernhardt TG.

Mol Microbiol. 2013 Aug;89(4):690-701. doi: 10.1111/mmi.12304. Epub 2013 Jul 23.


A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis.

Morlot C, Uehara T, Marquis KA, Bernhardt TG, Rudner DZ.

Genes Dev. 2010 Feb 15;24(4):411-22. doi: 10.1101/gad.1878110.


Novel secretion apparatus maintains spore integrity and developmental gene expression in Bacillus subtilis.

Doan T, Morlot C, Meisner J, Serrano M, Henriques AO, Moran CP Jr, Rudner DZ.

PLoS Genet. 2009 Jul;5(7):e1000566. doi: 10.1371/journal.pgen.1000566. Epub 2009 Jul 17.


Structural insights into the Slit-Robo complex.

Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA.

Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):14923-8. Epub 2007 Sep 11.


Production of Slit2 LRR domains in mammalian cells for structural studies and the structure of human Slit2 domain 3.

Morlot C, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA.

Acta Crystallogr D Biol Crystallogr. 2007 Sep;63(Pt 9):961-8. Epub 2007 Aug 17.


Cloning, expression, crystallization and preliminary X-ray analysis of the first two Ig domains from human roundabout 1 (Robo1).

Morlot C, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt 8):689-91. Epub 2007 Jul 21.


In vitro reconstitution of a trimeric complex of DivIB, DivIC and FtsL, and their transient co-localization at the division site in Streptococcus pneumoniae.

Noirclerc-Savoye M, Le Gouëllec A, Morlot C, Dideberg O, Vernet T, Zapun A.

Mol Microbiol. 2005 Jan;55(2):413-24.


Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae.

Morlot C, Pernot L, Le Gouellec A, Di Guilmi AM, Vernet T, Dideberg O, Dessen A.

J Biol Chem. 2005 Apr 22;280(16):15984-91. Epub 2004 Dec 13.


The D,D-carboxypeptidase PBP3 organizes the division process of Streptococcus pneumoniae.

Morlot C, Noirclerc-Savoye M, Zapun A, Dideberg O, Vernet T.

Mol Microbiol. 2004 Mar;51(6):1641-8.


Expression and purification of FtsW and RodA from Streptococcus pneumoniae, two membrane proteins involved in cell division and cell growth, respectively.

Noirclerc-Savoye M, Morlot C, Gérard P, Vernet T, Zapun A.

Protein Expr Purif. 2003 Jul;30(1):18-25.


Investigating the endonuclease activity of four Pyrococcus abyssi inteins.

Saves I, Morlot C, Thion L, Rolland JL, Diétrich J, Masson JM.

Nucleic Acids Res. 2002 Oct 1;30(19):4158-65.


[Retraction of the macular internal limiting membrane after surgery for retinal detachment].

Girard P, Forest A, Morlot C, Houtteville P.

Bull Soc Ophtalmol Fr. 1981 Jan;81(1):37-40. French. No abstract available.


[Undergoing retinal detachment and primitive ocular hypertension (author's transl)].

Forest A, Girard P, Morlot C, Rahmani F.

J Fr Ophtalmol. 1980 Dec;3(12):711-3. French.


[Treatment of retinal vascular accidents].

Girard P, Morlot C, Houtteville P, Forest A.

Rev Med Interne. 1980;1(2):259-63. French. No abstract available.


[Preliminary note on the use of the pilocarpine Ocusert in primary glaucoma].

Miller HA, Morlot C.

Bull Soc Ophtalmol Fr. 1977 Apr;77(4):397-400. French. No abstract available.


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