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Items: 1 to 50 of 113

1.

Meta-analysis of the psychometric properties of the Pain Catastrophizing Scale and associations with participant characteristics.

Wheeler CHB, Williams ACC, Morley SJ.

Pain. 2019 Sep;160(9):1946-1953. doi: 10.1097/j.pain.0000000000001494.

PMID:
30694929
2.

Probing the Anticancer Action of Novel Ferrocene Analogues of MNK Inhibitors.

Sansook S, Lineham E, Hassell-Hart S, Tizzard GJ, Coles SJ, Spencer J, Morley SJ.

Molecules. 2018 Aug 23;23(9). pii: E2126. doi: 10.3390/molecules23092126.

3.

Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells.

Lineham E, Tizzard GJ, Coles SJ, Spencer J, Morley SJ.

Oncotarget. 2018 Jan 31;9(18):14148-14159. doi: 10.18632/oncotarget.24354. eCollection 2018 Mar 6.

4.

Use of radiography in small animal practice in the UK and Republic of Ireland in 2013.

Booth NJ, Morley SJ, Ewers RS.

Vet Rec. 2018 Feb 24;182(8):225. doi: 10.1136/vr.104670. Epub 2018 Jan 31.

PMID:
29386251
5.

Dual abrogation of MNK and mTOR: a novel therapeutic approach for the treatment of aggressive cancers.

Lineham E, Spencer J, Morley SJ.

Future Med Chem. 2017 Sep;9(13):1539-1555. doi: 10.4155/fmc-2017-0062. Epub 2017 Aug 25. Review.

6.

The helicase, DDX3X, interacts with poly(A)-binding protein 1 (PABP1) and caprin-1 at the leading edge of migrating fibroblasts and is required for efficient cell spreading.

Copsey AC, Cooper S, Parker R, Lineham E, Lapworth C, Jallad D, Sweet S, Morley SJ.

Biochem J. 2017 Aug 30;474(18):3109-3120. doi: 10.1042/BCJ20170354.

7.

An efficient and cost-effective method of generating postnatal (P2-5) mouse primary hippocampal neuronal cultures.

Kaar A, Morley SJ, Rae MG.

J Neurosci Methods. 2017 Jul 15;286:69-77. doi: 10.1016/j.jneumeth.2017.05.020. Epub 2017 May 22.

PMID:
28546101
8.

Acetylated tubulin is essential for touch sensation in mice.

Morley SJ, Qi Y, Iovino L, Andolfi L, Guo D, Kalebic N, Castaldi L, Tischer C, Portulano C, Bolasco G, Shirlekar K, Fusco CM, Asaro A, Fermani F, Sundukova M, Matti U, Reymond L, De Ninno A, Businaro L, Johnsson K, Lazzarino M, Ries J, Schwab Y, Hu J, Heppenstall PA.

Elife. 2016 Dec 13;5. pii: e20813. doi: 10.7554/eLife.20813.

9.

Sumoylation of eIF4A2 affects stress granule formation.

Jongjitwimol J, Baldock RA, Morley SJ, Watts FZ.

J Cell Sci. 2016 Jun 15;129(12):2407-15. doi: 10.1242/jcs.184614. Epub 2016 May 9.

10.

Murine norovirus 1 (MNV1) replication induces translational control of the host by regulating eIF4E activity during infection.

Royall E, Doyle N, Abdul-Wahab A, Emmott E, Morley SJ, Goodfellow I, Roberts LO, Locker N.

J Biol Chem. 2015 Feb 20;290(8):4748-58. doi: 10.1074/jbc.M114.602649. Epub 2015 Jan 5.

11.
12.

Weighing up the possibilities: Controlling translation by ubiquitylation and sumoylation.

Watts FZ, Baldock R, Jongjitwimol J, Morley SJ.

Translation (Austin). 2014 Oct 30;2(2):e959366. doi: 10.4161/2169074X.2014.959366. eCollection 2014 Sep 1. Review.

13.

mTOR inhibition and levels of the DNA repair protein MGMT in T98G glioblastoma cells.

Smalley S, Chalmers AJ, Morley SJ.

Mol Cancer. 2014 Jun 8;13:144. doi: 10.1186/1476-4598-13-144.

14.

The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2.

Jongjitwimol J, Feng M, Zhou L, Wilkinson O, Small L, Baldock R, Taylor DL, Smith D, Bowler LD, Morley SJ, Watts FZ.

PLoS One. 2014 May 12;9(5):e94182. doi: 10.1371/journal.pone.0094182. eCollection 2014.

15.

Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis.

Coldwell MJ, Cowan JL, Vlasak M, Mead A, Willett M, Perry LS, Morley SJ.

Cell Cycle. 2013 Dec 1;12(23):3615-28. doi: 10.4161/cc.26588. Epub 2013 Oct 1.

16.

Requirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis by hypertonic conditions and mTOR inhibition.

Clemens MJ, Elia A, Morley SJ.

PLoS One. 2013 Aug 5;8(8):e71138. doi: 10.1371/journal.pone.0071138. Print 2013.

17.

Psychological approaches to chronic pain management: evidence and challenges.

Eccleston C, Morley SJ, Williams AC.

Br J Anaesth. 2013 Jul;111(1):59-63. doi: 10.1093/bja/aet207. Review.

18.

mRNA encoding WAVE-Arp2/3-associated proteins is co-localized with foci of active protein synthesis at the leading edge of MRC5 fibroblasts during cell migration.

Willett M, Brocard M, Pollard HJ, Morley SJ.

Biochem J. 2013 May 15;452(1):45-55. doi: 10.1042/BJ20121803.

PMID:
23452202
19.

Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon.

Coldwell MJ, Sack U, Cowan JL, Barrett RM, Vlasak M, Sivakumaran K, Morley SJ.

Biochem J. 2012 Nov 15;448(1):1-11. doi: 10.1042/BJ20111765.

PMID:
22909319
20.

SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians.

González-Estévez C, Felix DA, Smith MD, Paps J, Morley SJ, James V, Sharp TV, Aboobaker AA.

PLoS Genet. 2012;8(3):e1002619. doi: 10.1371/journal.pgen.1002619. Epub 2012 Mar 29.

21.

Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal death.

Vosler PS, Gao Y, Brennan CS, Yanagiya A, Gan Y, Cao G, Zhang F, Morley SJ, Sonenberg N, Bennett MV, Chen J.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18102-7. doi: 10.1073/pnas.1112635108. Epub 2011 Oct 17. Erratum in: Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):4020. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19968.

22.

Translation initiation factors and active sites of protein synthesis co-localize at the leading edge of migrating fibroblasts.

Willett M, Brocard M, Davide A, Morley SJ.

Biochem J. 2011 Aug 15;438(1):217-27. doi: 10.1042/BJ20110435.

PMID:
21539520
23.

Tailored treatment: it's not what you think it is. Comment on the article by van Koulil et al.

Vlaeyen JW, Morley SJ.

Arthritis Care Res (Hoboken). 2011 Jun;63(6):921-2; author reply 922-4. doi: 10.1002/acr.20455. No abstract available.

24.

Mitotic DNA damage targets the Aurora A/TPX2 complex.

Bhatia P, Menigatti M, Brocard M, Morley SJ, Ferrari S.

Cell Cycle. 2010 Nov 15;9(22):4592-9. Epub 2010 Nov 15.

PMID:
21099343
25.

LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.

James V, Zhang Y, Foxler DE, de Moor CH, Kong YW, Webb TM, Self TJ, Feng Y, Lagos D, Chu CY, Rana TM, Morley SJ, Longmore GD, Bushell M, Sharp TV.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12499-504. doi: 10.1073/pnas.0914987107. Epub 2010 Jun 28.

26.

Self-discrepancies in work-related upper extremity pain: relation to emotions and flexible-goal adjustment.

Goossens ME, Kindermans HP, Morley SJ, Roelofs J, Verbunt J, Vlaeyen JW.

Eur J Pain. 2010 Aug;14(7):764-70. doi: 10.1016/j.ejpain.2009.11.012. Epub 2009 Dec 24.

PMID:
20036169
27.

Localization of ribosomes and translation initiation factors to talin/beta3-integrin-enriched adhesion complexes in spreading and migrating mammalian cells.

Willett M, Pollard HJ, Vlasak M, Morley SJ.

Biol Cell. 2010 Feb 17;102(5):265-76. doi: 10.1042/BC20090141.

PMID:
19929852
28.

Kinky binding and SECsy insertions.

Morley SJ, Willett M.

Mol Cell. 2009 Aug 28;35(4):396-8. doi: 10.1016/j.molcel.2009.08.001.

29.

Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1.

Willett M, Cowan JL, Vlasak M, Coldwell MJ, Morley SJ.

Cell Signal. 2009 Oct;21(10):1504-12. doi: 10.1016/j.cellsig.2009.05.009. Epub 2009 May 27.

PMID:
19481146
30.

Imaging of the paranasal sinuses and nasal cavity: normal anatomy and clinically relevant anatomical variants.

Beale TJ, Madani G, Morley SJ.

Semin Ultrasound CT MR. 2009 Feb;30(1):2-16. Review.

PMID:
19388234
31.

Canonical initiation factor requirements of the Myc family of internal ribosome entry segments.

Spriggs KA, Cobbold LC, Jopling CL, Cooper RE, Wilson LA, Stoneley M, Coldwell MJ, Poncet D, Shen YC, Morley SJ, Bushell M, Willis AE.

Mol Cell Biol. 2009 Mar;29(6):1565-74. doi: 10.1128/MCB.01283-08. Epub 2009 Jan 5.

32.

Signaling pathways open the GAITway to translational control.

Morley SJ, Willett M.

Dev Cell. 2008 Nov;15(5):639-40. doi: 10.1016/j.devcel.2008.10.007.

33.

A cunning stunt: an alternative mechanism of eukaryotic translation initiation.

Morley SJ, Coldwell MJ.

Sci Signal. 2008 Jun 24;1(25):pe32. doi: 10.1126/scisignal.125pe32.

PMID:
18577757
34.

Phosphorylation by aurora-B negatively regulates survivin function during mitosis.

Wheatley SP, Barrett RM, Andrews PD, Medema RH, Morley SJ, Swedlow JR, Lens SM.

Cell Cycle. 2007 May 15;6(10):1220-30. Epub 2007 May 21.

PMID:
17457057
35.

Nutrient-responsive mTOR signalling grows on Sterile ground.

Cook SJ, Morley SJ.

Biochem J. 2007 Apr 1;403(1):e1-3.

36.

Functional analysis of individual binding activities of the scaffold protein eIF4G.

Hinton TM, Coldwell MJ, Carpenter GA, Morley SJ, Pain VM.

J Biol Chem. 2007 Jan 19;282(3):1695-708. Epub 2006 Nov 27.

37.

Specific isoforms of translation initiation factor 4GI show differences in translational activity.

Coldwell MJ, Morley SJ.

Mol Cell Biol. 2006 Nov;26(22):8448-60. Epub 2006 Sep 18.

38.

Compartmentalisation and localisation of the translation initiation factor (eIF) 4F complex in normally growing fibroblasts.

Willett M, Flint SA, Morley SJ, Pain VM.

Exp Cell Res. 2006 Sep 10;312(15):2942-53. Epub 2006 Jun 7.

PMID:
16822502
39.
40.

Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2.

Ling J, Morley SJ, Traugh JA.

EMBO J. 2005 Dec 7;24(23):4094-105. Epub 2005 Nov 10.

41.

Initiation factor modifications in the preapoptotic phase.

Morley SJ, Coldwell MJ, Clemens MJ.

Cell Death Differ. 2005 Jun;12(6):571-84. Review.

42.

Behavioural treatment for chronic low-back pain.

Ostelo RW, van Tulder MW, Vlaeyen JW, Linton SJ, Morley SJ, Assendelft WJ.

Cochrane Database Syst Rev. 2005 Jan 25;(1):CD002014. Review. Update in: Cochrane Database Syst Rev. 2010;(7):CD002014.

PMID:
15674889
43.

Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias.

Thorpe JR, Mosaheb S, Hashemzadeh-Bonehi L, Cairns NJ, Kay JE, Morley SJ, Rulten SL.

Neurobiol Dis. 2004 Nov;17(2):237-49.

PMID:
15474361
44.

Rapamycin-sensitive induction of eukaryotic initiation factor 4F in regenerating mouse liver.

Goggin MM, Nelsen CJ, Kimball SR, Jefferson LS, Morley SJ, Albrecht JH.

Hepatology. 2004 Sep;40(3):537-44.

PMID:
15349891
46.

Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress.

Naegele S, Morley SJ.

J Biol Chem. 2004 Oct 29;279(44):46023-34. Epub 2004 Aug 3.

47.

Expression of fragments of translation initiation factor eIF4GI reveals a nuclear localisation signal within the N-terminal apoptotic cleavage fragment N-FAG.

Coldwell MJ, Hashemzadeh-Bonehi L, Hinton TM, Morley SJ, Pain VM.

J Cell Sci. 2004 May 15;117(Pt 12):2545-55. Epub 2004 May 5.

48.
50.

Increased levels of the translation initiation factor eIF4E in differentiating epithelial lung tumor cell lines.

Walsh D, Meleady P, Power B, Morley SJ, Clynes M.

Differentiation. 2003 Mar;71(2):126-34.

PMID:
12641566

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