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Items: 24


The Association of Medications and Vaccination with Risk of Pneumonia in Inflammatory Bowel Disease.

Gregory MH, Ciorba MA, Wiitala WL, Stidham RW, Higgins P, Morley SC, Hou JK, Feagins LA, Govani SM, Cohen-Mekelburg SA, Waljee AK.

Inflamm Bowel Dis. 2019 Aug 27. pii: izz189. doi: 10.1093/ibd/izz189. [Epub ahead of print]


Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia.

Todd EM, Ramani R, Szasz TP, Morley SC.

Sci Adv. 2019 Aug 14;5(8):eaax3387. doi: 10.1126/sciadv.aax3387. eCollection 2019 Aug.


Cells under stress: The mechanical environment shapes inflammasome responses to danger signals.

Joshi H, Morley SC.

J Leukoc Biol. 2019 Jul;106(1):119-125. doi: 10.1002/JLB.3MIR1118-417R. Epub 2019 Jan 15. Review.


LRRK1 regulation of actin assembly in osteoclasts involves serine 5 phosphorylation of L-plastin.

Si M, Goodluck H, Zeng C, Pan S, Todd EM, Morley SC, Qin X, Mohan S, Xing W.

J Cell Biochem. 2018 Dec;119(12):10351-10357. doi: 10.1002/jcb.27377. Epub 2018 Aug 22.


Colonization with 19F and other pneumococcal conjugate vaccine serotypes in children in St. Louis, Missouri, USA.

McFarland M, Szasz TP, Zhou JY, Motley K, Sivapalan JS, Isaacson-Schmid M, Todd EM, Hogan PG, Fritz SA, Burnham CD, Hoffmann S, Morley SC.

Vaccine. 2017 Aug 3;35(34):4389-4395. doi: 10.1016/j.vaccine.2017.06.047. Epub 2017 Jul 4.


Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate.

Stewart-Hutchinson PJ, Szasz TP, Jaeger ER, Onken MD, Cooper JA, Morley SC.

J Leukoc Biol. 2017 Sep;102(3):941-948. doi: 10.1189/jlb.1TA0117-008R. Epub 2017 Jun 21.


Alveolar macrophage development in mice requires L-plastin for cellular localization in alveoli.

Todd EM, Zhou JY, Szasz TP, Deady LE, D'Angelo JA, Cheung MD, Kim AH, Morley SC.

Blood. 2016 Dec 15;128(24):2785-2796. Epub 2016 Oct 6.


L-Plastin promotes podosome longevity and supports macrophage motility.

Zhou JY, Szasz TP, Stewart-Hutchinson PJ, Sivapalan J, Todd EM, Deady LE, Cooper JA, Onken MD, Morley SC.

Mol Immunol. 2016 Oct;78:79-88. doi: 10.1016/j.molimm.2016.08.012. Epub 2016 Sep 7.


Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.

Xu X, Wang X, Todd EM, Jaeger ER, Vella JL, Mooren OL, Feng Y, Hu J, Cooper JA, Morley SC, Huang YH.

J Immunol. 2016 Sep 1;197(5):1683-91. doi: 10.4049/jimmunol.1600874. Epub 2016 Jul 27.


Klebsiella pneumoniae FimK Promotes Virulence in Murine Pneumonia.

Rosen DA, Hilliard JK, Tiemann KM, Todd EM, Morley SC, Hunstad DA.

J Infect Dis. 2016 Feb 15;213(4):649-58. doi: 10.1093/infdis/jiv440. Epub 2015 Sep 7.


Prevalence of nasopharyngeal pneumococcal colonization in children and antimicrobial susceptibility profiles of carriage isolates.

Zhou JY, Isaacson-Schmid M, Utterson EC, Todd EM, McFarland M, Sivapalan J, Niehoff JM, Burnham CD, Morley SC.

Int J Infect Dis. 2015 Oct;39:50-52. doi: 10.1016/j.ijid.2015.08.010. Epub 2015 Sep 3.


HIV-1 Nef drives macrophages into hiding.

Morley SC.

Blood. 2015 Mar 5;125(10):1512-3. doi: 10.1182/blood-2015-01-618983.


L-plastin is essential for alveolar macrophage production and control of pulmonary pneumococcal infection.

Deady LE, Todd EM, Davis CG, Zhou JY, Topcagic N, Edelson BT, Ferkol TW, Cooper MA, Muenzer JT, Morley SC.

Infect Immun. 2014 May;82(5):1982-93. doi: 10.1128/IAI.01199-13. Epub 2014 Mar 4.


Successful Use of Temocillin as Salvage Therapy for Cervical Osteomyelitis Secondary to Multidrug-Resistant Burkholderia cepacia.

Rodriguez M, Nelson M, Kelly JE, Elward A, Morley SC.

J Pediatric Infect Dis Soc. 2014 Mar;3(1):77-80. doi: 10.1093/jpids/pis110. Epub 2013 Jan 8.


The actin-bundling protein L-plastin supports T-cell motility and activation.

Morley SC.

Immunol Rev. 2013 Nov;256(1):48-62. doi: 10.1111/imr.12102. Review.


Intrinsic T- and B-cell defects impair T-cell-dependent antibody responses in mice lacking the actin-bundling protein L-plastin.

Todd EM, Deady LE, Morley SC.

Eur J Immunol. 2013 Jul;43(7):1735-44. doi: 10.1002/eji.201242780. Epub 2013 May 18.


The actin-bundling protein L-plastin: a critical regulator of immune cell function.

Morley SC.

Int J Cell Biol. 2012;2012:935173. doi: 10.1155/2012/935173. Epub 2011 Dec 13.


The actin-bundling protein L-plastin is essential for marginal zone B cell development.

Todd EM, Deady LE, Morley SC.

J Immunol. 2011 Sep 15;187(6):3015-25. doi: 10.4049/jimmunol.1101033. Epub 2011 Aug 10.


Actin-bundling protein L-plastin regulates T cell activation.

Wang C, Morley SC, Donermeyer D, Peng I, Lee WP, Devoss J, Danilenko DM, Lin Z, Zhang J, Zhou J, Allen PM, Brown EJ.

J Immunol. 2010 Dec 15;185(12):7487-97. doi: 10.4049/jimmunol.1001424. Epub 2010 Nov 12. Erratum in: J Immunol. 2011 Aug 1;187(3):1514.


The actin-bundling protein L-plastin dissociates CCR7 proximal signaling from CCR7-induced motility.

Morley SC, Wang C, Lo WL, Lio CW, Zinselmeyer BH, Miller MJ, Brown EJ, Allen PM.

J Immunol. 2010 Apr 1;184(7):3628-38. doi: 10.4049/jimmunol.0903851. Epub 2010 Mar 1.


Protein kinase C-theta is required for efficient positive selection.

Morley SC, Weber KS, Kao H, Allen PM.

J Immunol. 2008 Oct 1;181(7):4696-708.


Taking a toll road to better vaccines.

Morley SC, Allen PM.

Immunity. 2008 May;28(5):602-4. doi: 10.1016/j.immuni.2008.04.008.


Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells.

Morley SC, Sung J, Sun GP, Martelli MP, Bunnell SC, Bierer BE.

Mol Immunol. 2007 Mar;44(9):2469-80. Epub 2006 Dec 18.


The actin cytoskeleton, membrane lipid microdomains, and T cell signal transduction.

Morley SC, Bierer BE.

Adv Immunol. 2001;77:1-43. Review. No abstract available.


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