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Items: 45


Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus.

Nordengen K, Morland C, Slusher BS, Gundersen V.

Cereb Cortex. 2019 Aug 26. pii: bhz176. doi: 10.1093/cercor/bhz176. [Epub ahead of print]


High Intensity Interval Training Ameliorates Mitochondrial Dysfunction in the Left Ventricle of Mice with Type 2 Diabetes.

Bækkerud FH, Salerno S, Ceriotti P, Morland C, Storm-Mathisen J, Bergersen LH, Høydal MA, Catalucci D, Stølen TO.

Cardiovasc Toxicol. 2019 Oct;19(5):422-431. doi: 10.1007/s12012-019-09514-z.


Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in Bacteroides thetaiotaomicron Strains.

Joglekar P, Sonnenburg ED, Higginbottom SK, Earle KA, Morland C, Shapiro-Ward S, Bolam DN, Sonnenburg JL.

mSphere. 2018 May 23;3(3). pii: e00185-18. doi: 10.1128/mSphereDirect.00185-18. eCollection 2018 May-Jun.


The Janus Face of VEGF in Stroke.

Geiseler SJ, Morland C.

Int J Mol Sci. 2018 May 4;19(5). pii: E1362. doi: 10.3390/ijms19051362. Review.


Propionate enters GABAergic neurons, inhibits GABA transaminase, causes GABA accumulation and lethargy in a model of propionic acidemia.

Morland C, Frøland AS, Pettersen MN, Storm-Mathisen J, Gundersen V, Rise F, Hassel B.

Biochem J. 2018 Feb 16;475(4):749-758. doi: 10.1042/BCJ20170814.


Comprehensive functional characterization of the glycoside hydrolase family 3 enzymes from Cellvibrio japonicus reveals unique metabolic roles in biomass saccharification.

Nelson CE, Attia MA, Rogowski A, Morland C, Brumer H, Gardner JG.

Environ Microbiol. 2017 Dec;19(12):5025-5039. doi: 10.1111/1462-2920.13959. Epub 2017 Dec 7.


Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1.

Morland C, Andersson KA, Haugen ØP, Hadzic A, Kleppa L, Gille A, Rinholm JE, Palibrk V, Diget EH, Kennedy LH, Stølen T, Hennestad E, Moldestad O, Cai Y, Puchades M, Offermanns S, Vervaeke K, Bjørås M, Wisløff U, Storm-Mathisen J, Bergersen LH.

Nat Commun. 2017 May 23;8:15557. doi: 10.1038/ncomms15557.


Systems analysis in Cellvibrio japonicus resolves predicted redundancy of β-glucosidases and determines essential physiological functions.

Nelson CE, Rogowski A, Morland C, Wilhide JA, Gilbert HJ, Gardner JG.

Mol Microbiol. 2017 Apr;104(2):294-305. doi: 10.1111/mmi.13625. Epub 2017 Feb 28.


Hyperosmolar sodium chloride is toxic to cultured neurons and causes reduction of glucose metabolism and ATP levels, an increase in glutamate uptake, and a reduction in cytosolic calcium.

Morland C, Pettersen MN, Hassel B.

Neurotoxicology. 2016 May;54:34-43. doi: 10.1016/j.neuro.2016.03.005. Epub 2016 Mar 17.


Corrigendum: Glycan complexity dictates microbial resource allocation in the large intestine.

Rogowski A, Briggs JA, Mortimer JC, Tryfona T, Terrapon N, Lowe EC, Baslé A, Morland C, Day AM, Zheng H, Rogers TE, Thompson P, Hawkins AR, Yadav MP, Henrissat B, Martens EC, Dupree P, Gilbert HJ, Bolam DN.

Nat Commun. 2016 Feb 5;7:10705. doi: 10.1038/ncomms10705. No abstract available.


Recognition of xyloglucan by the crystalline cellulose-binding site of a family 3a carbohydrate-binding module.

Hernandez-Gomez MC, Rydahl MG, Rogowski A, Morland C, Cartmell A, Crouch L, Labourel A, Fontes CM, Willats WG, Gilbert HJ, Knox JP.

FEBS Lett. 2015 Aug 19;589(18):2297-303. doi: 10.1016/j.febslet.2015.07.009. Epub 2015 Jul 18.


Glycan complexity dictates microbial resource allocation in the large intestine.

Rogowski A, Briggs JA, Mortimer JC, Tryfona T, Terrapon N, Lowe EC, Baslé A, Morland C, Day AM, Zheng H, Rogers TE, Thompson P, Hawkins AR, Yadav MP, Henrissat B, Martens EC, Dupree P, Gilbert HJ, Bolam DN.

Nat Commun. 2015 Jun 26;6:7481. doi: 10.1038/ncomms8481. Erratum in: Nat Commun. 2016;7:10705.


The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain.

Morland C, Lauritzen KH, Puchades M, Holm-Hansen S, Andersson K, Gjedde A, Attramadal H, Storm-Mathisen J, Bergersen LH.

J Neurosci Res. 2015 Jul;93(7):1045-55. doi: 10.1002/jnr.23593. Epub 2015 Apr 16. Review.


Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism.

Lauritzen KH, Morland C, Puchades M, Holm-Hansen S, Hagelin EM, Lauritzen F, Attramadal H, Storm-Mathisen J, Gjedde A, Bergersen LH.

Cereb Cortex. 2014 Oct;24(10):2784-95. doi: 10.1093/cercor/bht136. Epub 2013 May 21.


Vesicular uptake and exocytosis of L-aspartate is independent of sialin.

Morland C, Nordengen K, Larsson M, Prolo LM, Farzampour Z, Reimer RJ, Gundersen V.

FASEB J. 2013 Mar;27(3):1264-74. doi: 10.1096/fj.12-206300. Epub 2012 Dec 6.


How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity.

Cuskin F, Flint JE, Gloster TM, Morland C, Baslé A, Henrissat B, Coutinho PM, Strazzulli A, Solovyova AS, Davies GJ, Gilbert HJ.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20889-94. doi: 10.1073/pnas.1212034109. Epub 2012 Dec 3.


Pre- and postsynaptic localization of NMDA receptor subunits at hippocampal mossy fibre synapses.

Berg LK, Larsson M, Morland C, Gundersen V.

Neuroscience. 2013 Jan 29;230:139-50. doi: 10.1016/j.neuroscience.2012.10.061. Epub 2012 Nov 14.


Valproate causes reduction of the excitatory amino acid aspartate in nerve terminals.

Morland C, Nordengen K, Gundersen V.

Neurosci Lett. 2012 Oct 11;527(2):100-4. doi: 10.1016/j.neulet.2012.08.042. Epub 2012 Aug 30.


Immunogold detection of L-glutamate and D-serine in small synaptic-like microvesicles in adult hippocampal astrocytes.

Bergersen LH, Morland C, Ormel L, Rinholm JE, Larsson M, Wold JF, Røe AT, Stranna A, Santello M, Bouvier D, Ottersen OP, Volterra A, Gundersen V.

Cereb Cortex. 2012 Jul;22(7):1690-7. doi: 10.1093/cercor/bhr254. Epub 2011 Sep 12.


Functional and anatomical identification of a vesicular transporter mediating neuronal ATP release.

Larsson M, Sawada K, Morland C, Hiasa M, Ormel L, Moriyama Y, Gundersen V.

Cereb Cortex. 2012 May;22(5):1203-14. doi: 10.1093/cercor/bhr203. Epub 2011 Aug 1.


The sodium-dependent inorganic phosphate transporter SLC34A1 (NaPi-IIa) is not localized in the mouse brain: a case of tissue-specific antigenic cross-reactivity.

Larsson M, Morland C, Poblete-Naredo I, Biber J, Danbolt NC, Gundersen V.

J Histochem Cytochem. 2011 Sep;59(9):807-12. doi: 10.1369/0022155411411713. Epub 2011 May 23.


Understanding how diverse beta-mannanases recognize heterogeneous substrates.

Tailford LE, Ducros VM, Flint JE, Roberts SM, Morland C, Zechel DL, Smith N, Bjørnvad ME, Borchert TV, Wilson KS, Davies GJ, Gilbert HJ.

Biochemistry. 2009 Jul 28;48(29):7009-18. doi: 10.1021/bi900515d.


The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions.

Montanier C, Money VA, Pires VM, Flint JE, Pinheiro BA, Goyal A, Prates JA, Izumi A, Stålbrand H, Morland C, Cartmell A, Kolenova K, Topakas E, Dodson EJ, Bolam DN, Davies GJ, Fontes CM, Gilbert HJ.

PLoS Biol. 2009 Mar 31;7(3):e71. doi: 10.1371/journal.pbio.1000071.


Engineering hyperthermostability into a GH11 xylanase is mediated by subtle changes to protein structure.

Dumon C, Varvak A, Wall MA, Flint JE, Lewis RJ, Lakey JH, Morland C, Luginbühl P, Healey S, Todaro T, DeSantis G, Sun M, Parra-Gessert L, Tan X, Weiner DP, Gilbert HJ.

J Biol Chem. 2008 Aug 15;283(33):22557-64. doi: 10.1074/jbc.M800936200. Epub 2008 May 30.


Structural and biochemical evidence for a boat-like transition state in beta-mannosidases.

Tailford LE, Offen WA, Smith NL, Dumon C, Morland C, Gratien J, Heck MP, Stick RV, Blériot Y, Vasella A, Gilbert HJ, Davies GJ.

Nat Chem Biol. 2008 May;4(5):306-12. doi: 10.1038/nchembio.81.


Expectations and experience of labial reduction: a qualitative study.

Bramwell R, Morland C, Garden AS.

BJOG. 2007 Dec;114(12):1493-9. Epub 2007 Sep 17.


Evidence for a higher glycolytic than oxidative metabolic activity in white matter of rat brain.

Morland C, Henjum S, Iversen EG, Skrede KK, Hassel B.

Neurochem Int. 2007 Apr;50(5):703-9. Epub 2007 Jan 20.


Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia.

Nguyen NH, Morland C, Gonzalez SV, Rise F, Storm-Mathisen J, Gundersen V, Hassel B.

J Neurochem. 2007 May;101(3):806-14. Epub 2007 Feb 5.


Galactomannan hydrolysis and mannose metabolism in Cellvibrio mixtus.

Centeno MS, Guerreiro CI, Dias FM, Morland C, Tailford LE, Goyal A, Prates JA, Ferreira LM, Caldeira RM, Mongodin EF, Nelson KE, Gilbert HJ, Fontes CM.

FEMS Microbiol Lett. 2006 Aug;261(1):123-32.


How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: structure and activity of a Clostridium thermocellum lichenase, CtLic26A.

Taylor EJ, Goyal A, Guerreiro CI, Prates JA, Money VA, Ferry N, Morland C, Planas A, Macdonald JA, Stick RV, Gilbert HJ, Fontes CM, Davies GJ.

J Biol Chem. 2005 Sep 23;280(38):32761-7. Epub 2005 Jun 28.


Valproate is neuroprotective against malonate toxicity in rat striatum: an association with augmentation of high-affinity glutamate uptake.

Morland C, Boldingh KA, Iversen EG, Hassel B.

J Cereb Blood Flow Metab. 2004 Nov;24(11):1226-34.


Common inhibition of both beta-glucosidases and beta-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis.

Vincent F, Gloster TM, Macdonald J, Morland C, Stick RV, Dias FM, Prates JA, Fontes CM, Gilbert HJ, Davies GJ.

Chembiochem. 2004 Nov 5;5(11):1596-9. No abstract available.


Family 6 carbohydrate binding modules recognize the non-reducing end of beta-1,3-linked glucans by presenting a unique ligand binding surface.

van Bueren AL, Morland C, Gilbert HJ, Boraston AB.

J Biol Chem. 2005 Jan 7;280(1):530-7. Epub 2004 Oct 22.


Differential expression of chemokines and chemokine receptors shapes the inflammatory response in rejecting human liver transplants.

Goddard S, Williams A, Morland C, Qin S, Gladue R, Hubscher SG, Adams DH.

Transplantation. 2001 Dec 27;72(12):1957-67.


Migration of CD18-deficient neutrophils in vitro: evidence for a CD18-independent pathway induced by IL-8.

Morland CM, Morland BJ, Darbyshire PJ, Stockley RA.

Biochim Biophys Acta. 2000 Jan 3;1500(1):70-6.


Calcium protects a mesophilic xylanase from proteinase inactivation and thermal unfolding.

Spurway TD, Morland C, Cooper A, Sumner I, Hazlewood GP, O'Donnell AG, Pickersgill RW, Gilbert HJ.

J Biol Chem. 1997 Jul 11;272(28):17523-30.


Promotion of leukocyte transendothelial cell migration by chemokines derived from human biliary epithelial cells in vitro.

Morland CM, Fear J, McNab G, Joplin R, Adams DH.

Proc Assoc Am Physicians. 1997 Jul;109(4):372-82.


Inflammatory cytokines stimulate human biliary epithelial cells to express interleukin-8 and monocyte chemotactic protein-1.

Morland CM, Fear J, Joplin R, Adams DH.

Biochem Soc Trans. 1997 May;25(2):232S. No abstract available.


Cell cultures from bronchial subepithelial myofibroblasts enhance eosinophil survival in vitro.

Zhang S, Mohammed Q, Burbidge A, Morland CM, Roche WR.

Eur Respir J. 1996 Sep;9(9):1839-46.


Selective eosinophil leukocyte recruitment by transendothelial migration and not by leukocyte-endothelial cell adhesion.

Morland CM, Wilson SJ, Holgate ST, Roche WR.

Am J Respir Cell Mol Biol. 1992 May;6(5):557-66.


Anti-idiotype and immunosuppressant treatment of murine lupus.

Morland C, Michael J, Adu D, Kizaki T, Howie AJ, Morgan A, Staines NA.

Clin Exp Immunol. 1991 Jan;83(1):126-32.


IgG subclasses of PEG precipitable IgG in systemic lupus erythematosus sera.

Morland C, Michael J, Adu D.

Clin Nephrol. 1989 Apr;31(4):204-9.


Different types of segmental sclerosing glomerular lesions in six experimental models of proteinuria.

Howie AJ, Kizaki T, Beaman M, Morland CM, Birtwistle RJ, Adu D, Michael J, Williams AJ, Walls J, Matsuyama M, et al.

J Pathol. 1989 Feb;157(2):141-51.


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