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Items: 1 to 50 of 480

1.

The enhancement of subcutaneous first-pass metabolism causes non-linear pharmacokinetics of TAK-448 after a single subcutaneous administration to rats.

Moriya Y, Kogame A, Tagawa Y, Morohashi A, Kondo T, Asahi S, Benet LZ.

Drug Metab Dispos. 2019 Jun 14. pii: dmd.119.087148. doi: 10.1124/dmd.119.087148. [Epub ahead of print]

2.

Bond strengths between gingiva-colored layering resin composite and zirconia frameworks coated with feldspathic porcelain.

Fushiki R, Komine F, Kimura F, Kusaba K, Kondo T, Moriya Y, Matsumura H.

Dent Mater J. 2019 May 17. doi: 10.4012/dmj.2018-253. [Epub ahead of print]

3.

Characterization of Fasiglifam-Related Liver Toxicity in Dogs.

Kogame A, Moriya Y, Mori I, Pan L, Morohashi A, Ebihara T, Fukui H, Tagawa Y, Benet LZ.

Drug Metab Dispos. 2019 May;47(5):525-534. doi: 10.1124/dmd.118.084889. Epub 2019 Feb 14.

PMID:
30765394
4.

Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice.

Kasahara Y, Sakakibara Y, Hiratsuka T, Moriya Y, Lesch KP, Hall FS, Uhl GR, Sora I.

Neuropsychopharmacol Rep. 2019 Jun;39(2):130-133. doi: 10.1002/npr2.12049. Epub 2019 Feb 4.

5.

TogoGenome/TogoStanza: modularized Semantic Web genome database.

Katayama T, Kawashima S, Okamoto S, Moriya Y, Chiba H, Naito Y, Fujisawa T, Mori H, Takagi T.

Database (Oxford). 2019 Jan 1;2019. doi: 10.1093/database/bay132.

6.

Predictive factors of pathological lateral pelvic lymph node metastasis in patients without clinical lateral pelvic lymph node metastasis (clinical stage II/III): The analysis of data from the clinical trial (JCOG0212).

Komori K, Fujita S, Mizusawa J, Kanemitsu Y, Ito M, Shiomi A, Ohue M, Ota M, Akazai Y, Shiozawa M, Yamaguchi T, Bandou H, Katsumata K, Kinugasa Y, Takii Y, Akasu T, Moriya Y; Colorectal Cancer Study Group of Japan Clinical Oncology Group.

Eur J Surg Oncol. 2019 Mar;45(3):336-340. doi: 10.1016/j.ejso.2018.11.016. Epub 2018 Nov 20.

PMID:
30477950
7.

Effect of veneering materials on fracture loads of implant-supported zirconia molar fixed dental prostheses.

Kondo T, Komine F, Honda J, Takata H, Moriya Y.

J Prosthodont Res. 2019 Apr;63(2):140-144. doi: 10.1016/j.jpor.2018.10.006. Epub 2018 Nov 13.

8.

Investigation on nitridation processes of Sr2Nb2O7 and SrNbO3 to SrNbO2N for photoelectrochemical water splitting.

Kodera M, Moriya Y, Katayama M, Hisatomi T, Minegishi T, Domen K.

Sci Rep. 2018 Oct 26;8(1):15849. doi: 10.1038/s41598-018-34184-2.

9.

MicroRNA induction by copy number gain is associated with poor outcome in squamous cell carcinoma of the lung.

Xia E, Kanematsu S, Suenaga Y, Elzawahry A, Kondo H, Otsuka N, Moriya Y, Iizasa T, Kato M, Yoshino I, Yokoi S.

Sci Rep. 2018 Oct 18;8(1):15363. doi: 10.1038/s41598-018-33696-1.

10.

The jPOST environment: an integrated proteomics data repository and database.

Moriya Y, Kawano S, Okuda S, Watanabe Y, Matsumoto M, Takami T, Kobayashi D, Yamanouchi Y, Araki N, Yoshizawa AC, Tabata T, Iwasaki M, Sugiyama N, Tanaka S, Goto S, Ishihama Y.

Nucleic Acids Res. 2019 Jan 8;47(D1):D1218-D1224. doi: 10.1093/nar/gky899.

11.

Investigation of disposition for TAK-448, a synthetic peptide of kisspeptin analog, in rats and dogs using the radiolabeled TAK-448 suitable for pharmacokinetic study.

Moriya Y, Kogame A, Tagawa Y, Morohashi A, Kondo T, Asahi S.

Xenobiotica. 2019 Jul;49(7):833-839. doi: 10.1080/00498254.2018.1499152. Epub 2018 Sep 12.

PMID:
30044673
12.

MAPLE 2.3.0: an improved system for evaluating the functionomes of genomes and metagenomes.

Arai W, Taniguchi T, Goto S, Moriya Y, Uehara H, Takemoto K, Ogata H, Takami H.

Biosci Biotechnol Biochem. 2018 Sep;82(9):1515-1517. doi: 10.1080/09168451.2018.1476122. Epub 2018 May 24.

PMID:
29792119
13.

Prospective registry database of patients with malignant mesothelioma: directions for a future Japanese registry-based lung cancer study.

Shintani Y, Hasegawa S, Takuwa T, Aoe K, Kato K, Fujimoto N, Hida Y, Morise M, Moriya Y, Morohoshi T, Okumura M, Yoshino I.

J Thorac Dis. 2018 Mar;10(3):1968-1971. doi: 10.21037/jtd.2018.03.53.

14.

Disposition and metabolism of the G protein-coupled receptor 40 agonist TAK-875 (fasiglifam) in rats, dogs, and humans.

Kogame A, Lee R, Pan L, Sudo M, Nonaka M, Moriya Y, Higuchi T, Tagawa Y.

Xenobiotica. 2019 Apr;49(4):433-445. doi: 10.1080/00498254.2018.1453100. Epub 2018 Apr 5.

PMID:
29557709
15.

Urinary dysfunction after rectal cancer surgery: Results from a randomized trial comparing mesorectal excision with and without lateral lymph node dissection for clinical stage II or III lower rectal cancer (Japan Clinical Oncology Group Study, JCOG0212).

Ito M, Kobayashi A, Fujita S, Mizusawa J, Kanemitsu Y, Kinugasa Y, Komori K, Ohue M, Ota M, Akazai Y, Shiozawa M, Yamaguchi T, Akasu T, Moriya Y; Colorectal Cancer Study Group of Japan Clinical Oncology Group.

Eur J Surg Oncol. 2018 Apr;44(4):463-468. doi: 10.1016/j.ejso.2018.01.015. Epub 2018 Jan 17.

PMID:
29428473
16.

Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) Complicated by Perforation of the Small Intestine and Cholecystitis.

Ohnuki Y, Moriya Y, Yutani S, Mizuma A, Nakayama T, Ohnuki Y, Uda S, Inomoto C, Yamamoto S, Nakamura N, Takizawa S.

Intern Med. 2018 Mar 1;57(5):737-740. doi: 10.2169/internalmedicine.8975-17. Epub 2017 Dec 21.

17.

Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis.

Onuma Y, Oki M, Komatsu M, Ishitani S, Kijima K, Fukuda R, Moriya Y, Ozawa H, Takagi A.

J Gen Fam Med. 2017 Jun 21;18(6):436-438. doi: 10.1002/jgf2.91. eCollection 2017 Dec.

18.

Is There Any Reason to Still Consider Lateral Lymph Node Dissection in Rectal Cancer? Rationale and Technique.

Kusters M, Uehara K, Velde CJHV, Moriya Y.

Clin Colon Rectal Surg. 2017 Nov;30(5):346-356. doi: 10.1055/s-0037-1606112. Epub 2017 Nov 27. Review.

19.

Capecitabine versus S-1 as adjuvant chemotherapy for patients with stage III colorectal cancer (JCOG0910): an open-label, non-inferiority, randomised, phase 3, multicentre trial.

Hamaguchi T, Shimada Y, Mizusawa J, Kinugasa Y, Kanemitsu Y, Ohue M, Fujii S, Takiguchi N, Yatsuoka T, Takii Y, Ojima H, Masuko H, Kubo Y, Mishima H, Yamaguchi T, Bando H, Sato T, Kato T, Nakamura K, Fukuda H, Moriya Y.

Lancet Gastroenterol Hepatol. 2018 Jan;3(1):47-56. doi: 10.1016/S2468-1253(17)30297-2. Epub 2017 Oct 24.

PMID:
29079411
20.

Mode of action of pertuzumab in combination with trastuzumab plus docetaxel therapy in a HER2-positive breast cancer xenograft model.

Yamashita-Kashima Y, Shu S, Yorozu K, Moriya Y, Harada N.

Oncol Lett. 2017 Oct;14(4):4197-4205. doi: 10.3892/ol.2017.6679. Epub 2017 Jul 26.

21.

Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Yamamoto M, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S.

Biopharm Drug Dispos. 2017 Dec;38(9):543-552. doi: 10.1002/bdd.2106. Epub 2017 Nov 9.

PMID:
28948605
22.

Neurological safety of fingolimod: An updated review.

Yoshii F, Moriya Y, Ohnuki T, Ryo M, Takahashi W.

Clin Exp Neuroimmunol. 2017 Aug;8(3):233-243. doi: 10.1111/cen3.12397. Epub 2017 Jun 18. Review.

23.

Japanese genome-wide association study identifies a significant colorectal cancer susceptibility locus at chromosome 10p14.

Takahashi Y, Sugimachi K, Yamamoto K, Niida A, Shimamura T, Sato T, Watanabe M, Tanaka J, Kudo S, Sugihara K, Hase K, Kusunoki M, Yamada K, Shimada Y, Moriya Y, Suzuki Y, Miyano S, Mori M, Mimori K.

Cancer Sci. 2017 Nov;108(11):2239-2247. doi: 10.1111/cas.13391. Epub 2017 Sep 26.

24.

Postoperative Chemoradiotherapy After Local Resection for High-Risk T1 to T2 Low Rectal Cancer: Results of a Single-Arm, Multi-Institutional, Phase II Clinical Trial.

Sasaki T, Ito Y, Ohue M, Kanemitsu Y, Kobatake T, Ito M, Moriya Y, Saito N.

Dis Colon Rectum. 2017 Sep;60(9):914-921. doi: 10.1097/DCR.0000000000000870.

25.

Microbleeds, Cerebral Hemorrhage, and Functional Outcome After Stroke Thrombolysis.

Charidimou A, Turc G, Oppenheim C, Yan S, Scheitz JF, Erdur H, Klinger-Gratz PP, El-Koussy M, Takahashi W, Moriya Y, Wilson D, Kidwell CS, Saver JL, Sallem A, Moulin S, Edjlali-Goujon M, Thijs V, Fox Z, Shoamanesh A, Albers GW, Mattle HP, Benavente OR, Jäger HR, Ambler G, Aoki J, Baron JC, Kimura K, Kakuda W, Takizawa S, Jung S, Nolte CH, Lou M, Cordonnier C, Werring DJ.

Stroke. 2017 Aug;48(8):2084-2090. doi: 10.1161/STROKEAHA.116.012992. Review.

PMID:
28720659
26.

123I-Meta-iodobenzylguanidine (MIBG) myocardial scintigraphy in patients showing scans without evidence of dopaminergic deficits (SWEDDs).

Yoshii F, Moriya Y, Ohnuki T, Ryo M, Takahashi W, Kohara S, Hashimoto J.

Clin Neurol Neurosurg. 2017 Sep;160:73-77. doi: 10.1016/j.clineuro.2017.06.017. Epub 2017 Jun 27.

PMID:
28689103
27.

Prognostic Impact of Intra-abdominal/Pelvic Inflammation After Radical Surgery for Locally Recurrent Rectal Cancer.

Tanaka M, Kanemitsu Y, Shida D, Ochiai H, Tsukamoto S, Nagino M, Moriya Y.

Dis Colon Rectum. 2017 Aug;60(8):827-836. doi: 10.1097/DCR.0000000000000853.

PMID:
28682968
28.

Inositol Hexakisphosphate Kinase 2 is a Presymptomatic Biomarker for Amyotrophic Lateral Sclerosis.

Moriya Y, Nagata E, Fujii N, Satoh T, Ogawa H, Hadano S, Takizawa S.

Tokai J Exp Clin Med. 2017 Apr 20;42(1):13-18.

29.

Survival outcomes following laparoscopic versus open D3 dissection for stage II or III colon cancer (JCOG0404): a phase 3, randomised controlled trial.

Kitano S, Inomata M, Mizusawa J, Katayama H, Watanabe M, Yamamoto S, Ito M, Saito S, Fujii S, Konishi F, Saida Y, Hasegawa H, Akagi T, Sugihara K, Yamaguchi T, Masaki T, Fukunaga Y, Murata K, Okajima M, Moriya Y, Shimada Y.

Lancet Gastroenterol Hepatol. 2017 Apr;2(4):261-268. doi: 10.1016/S2468-1253(16)30207-2. Epub 2017 Feb 2.

PMID:
28404155
30.

Potential impact of lateral lymph node dissection (LLND) for low rectal cancer on prognoses and local control: A comparison of 2 high-volume centers in Japan that employ different policies concerning LLND.

Kanemitsu Y, Komori K, Shida D, Ochiai H, Tsukamoto S, Kinoshita T, Moriya Y.

Surgery. 2017 Aug;162(2):303-314. doi: 10.1016/j.surg.2017.02.005. Epub 2017 Mar 30.

PMID:
28366499
31.

Influence of the pharmacokinetic profile on the plasma glucose lowering effect of the PPARγ agonist pioglitazone in Wistar fatty rats.

Goto A, Tagawa Y, Kimura Y, Kogame A, Moriya Y, Amano N.

Biopharm Drug Dispos. 2017 Sep;38(6):381-388. doi: 10.1002/bdd.2076. Epub 2017 May 28.

PMID:
28294376
32.

Mesorectal Excision With or Without Lateral Lymph Node Dissection for Clinical Stage II/III Lower Rectal Cancer (JCOG0212): A Multicenter, Randomized Controlled, Noninferiority Trial.

Fujita S, Mizusawa J, Kanemitsu Y, Ito M, Kinugasa Y, Komori K, Ohue M, Ota M, Akazai Y, Shiozawa M, Yamaguchi T, Bandou H, Katsumata K, Murata K, Akagi Y, Takiguchi N, Saida Y, Nakamura K, Fukuda H, Akasu T, Moriya Y; Colorectal Cancer Study Group of Japan Clinical Oncology Group.

Ann Surg. 2017 Aug;266(2):201-207. doi: 10.1097/SLA.0000000000002212.

PMID:
28288057
33.

Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto A, Tagawa Y, Moriya Y, Sato S, Furukawa Y, Wakabayashi T, Tsukamoto T, DeJongh J, van Steeg TJ, Moriwaki T, Asahi S.

Biopharm Drug Dispos. 2017 Sep;38(6):373-380. doi: 10.1002/bdd.2075. Epub 2017 May 23.

PMID:
28256717
34.

Changes in apolipoprotein B and oxidized low-density lipoprotein levels in gingival crevicular fluids as a result of periodontal tissue conditions.

Ishizuka M, Kato R, Moriya Y, Noguchi E, Koide Y, Inoue S, Itabe H, Yamamoto M.

J Periodontal Res. 2017 Jun;52(3):594-602. doi: 10.1111/jre.12427. Epub 2017 Feb 24.

PMID:
28233905
35.

Fasiglifam (TAK-875) Alters Bile Acid Homeostasis in Rats and Dogs: A Potential Cause of Drug Induced Liver Injury.

Wolenski FS, Zhu AZX, Johnson M, Yu S, Moriya Y, Ebihara T, Csizmadia V, Grieves J, Paton M, Liao M, Gemski C, Pan L, Vakilynejad M, Dragan YP, Chowdhury SK, Kirby PJ.

Toxicol Sci. 2017 May 1;157(1):50-61. doi: 10.1093/toxsci/kfx018.

36.

Early Motor Fluctuations in a Patient with Striatonigral Degeneration.

Yoshii F, Moriya Y, Ohnuki T, Takahashi W, Ryo M.

Case Rep Neurol. 2016 Dec 13;8(3):243-250. doi: 10.1159/000453254. eCollection 2016 Sep-Dec.

37.

Quantitative proteomic analysis of gingival crevicular fluids from deciduous and permanent teeth.

Moriya Y, Obama T, Aiuchi T, Sugiyama T, Endo Y, Koide Y, Noguchi E, Ishizuka M, Inoue M, Itabe H, Yamamoto M.

J Clin Periodontol. 2017 Apr;44(4):353-362. doi: 10.1111/jcpe.12696. Epub 2017 Mar 6.

PMID:
28092104
38.

Pemetrexed for epithelioid haemangioendothelioma of the pleura.

Kanemura S, Kuribayashi K, Moriya Y, Shimizu S, Tsujimura T, Nakano T.

Respirol Case Rep. 2016 Sep 25;4(6):e00191. doi: 10.1002/rcr2.191. eCollection 2016 Nov.

39.

jPOSTrepo: an international standard data repository for proteomes.

Okuda S, Watanabe Y, Moriya Y, Kawano S, Yamamoto T, Matsumoto M, Takami T, Kobayashi D, Araki N, Yoshizawa AC, Tabata T, Sugiyama N, Goto S, Ishihama Y.

Nucleic Acids Res. 2017 Jan 4;45(D1):D1107-D1111. doi: 10.1093/nar/gkw1080. Epub 2016 Nov 28.

40.

The Outcomes of a Limited Resection for Non-Small Cell Lung Cancer Based on Differences in Pathology.

Yano M, Yoshida J, Koike T, Kameyama K, Shimamoto A, Nishio W, Yoshimoto K, Utsumi T, Shiina T, Watanabe A, Yamato Y, Watanabe T, Takahashi Y, Sonobe M, Kuroda H, Oda M, Inoue M, Tanahashi M, Adachi H, Saito M, Hayashi M, Otsuka H, Mizobuchi T, Moriya Y, Takahashi M, Nishikawa S, Matsumura Y, Moriyama S, Fujii Y.

World J Surg. 2016 Nov;40(11):2688-2697.

PMID:
27365098
41.

Disposition of the Highly Fat Distributed Compound 1-(4-Methoxyphenyl)-4-(2,2,4,6,7-Pentamethyl -2,3-Dihydro-1-Benzofuran-5-yl)Piperazine (TAK-357) in Rats and Dogs.

Goto A, Moriya Y, Mandai T, Wakabayashi T, Tsukamoto T, Tagawa Y, Kondo T, Asahi S.

Drug Res (Stuttg). 2017 Jan;67(1):38-45. doi: 10.1055/s-0042-117624. Epub 2016 Oct 11.

PMID:
27728931
42.

Male sexual dysfunction after rectal cancer surgery: Results of a randomized trial comparing mesorectal excision with and without lateral lymph node dissection for patients with lower rectal cancer: Japan Clinical Oncology Group Study JCOG0212.

Saito S, Fujita S, Mizusawa J, Kanemitsu Y, Saito N, Kinugasa Y, Akazai Y, Ota M, Ohue M, Komori K, Shiozawa M, Yamaguchi T, Akasu T, Moriya Y; Colorectal Cancer Study Group of Japan Clinical Oncology Group.

Eur J Surg Oncol. 2016 Dec;42(12):1851-1858. doi: 10.1016/j.ejso.2016.07.010. Epub 2016 Jul 30.

PMID:
27519616
43.

Aniseikonia and Foveal Microstructure in Patients with Idiopathic Macular Hole.

Okamoto F, Sugiura Y, Moriya Y, Murakami T, Okamoto Y, Hiraoka T, Oshika T.

Ophthalmology. 2016 Sep;123(9):1926-32. doi: 10.1016/j.ophtha.2016.05.051. Epub 2016 Jul 9.

PMID:
27406114
44.

An automated system for evaluation of the potential functionome: MAPLE version 2.1.0.

Takami H, Taniguchi T, Arai W, Takemoto K, Moriya Y, Goto S.

DNA Res. 2016 Jul 3. pii: dsw030. [Epub ahead of print]

45.

Characteristics and Clinical Outcomes of Duodenal Neoplasia in Japanese Patients With Familial Adenomatous Polyposis.

Yachida T, Nakajima T, Nonaka S, Nakamura K, Suzuki H, Yoshinaga S, Oda I, Moriya Y, Masaki T, Saito Y.

J Clin Gastroenterol. 2017 May/Jun;51(5):407-411. doi: 10.1097/MCG.0000000000000555.

PMID:
27306941
46.

Fingolimod-induced leukoencephalopathy in a patient with neuromyelitis optica spectrum disorder.

Yoshii F, Moriya Y, Ohnuki T, Ryo M, Takahashi W.

Mult Scler Relat Disord. 2016 May;7:53-7. doi: 10.1016/j.msard.2016.03.004. Epub 2016 Mar 16.

PMID:
27237757
47.

Early and late recurrence after intentional limited resection for cT1aN0M0, non-small cell lung cancer: from a multi-institutional, retrospective analysis in Japan.

Matsumura Y, Yano M, Yoshida J, Koike T, Kameyama K, Shimamoto A, Nishio W, Yoshimoto K, Utsumi T, Shiina T, Watanabe A, Yamato Y, Watanabe T, Takahashi Y, Sonobe M, Kuroda H, Oda M, Inoue M, Tanahashi M, Adachi H, Saito M, Hayashi M, Otsuka H, Mizobuchi T, Moriya Y, Takahashi M, Nishikawa S, Suzuki H; Japanese Association for Chest Surgery.

Interact Cardiovasc Thorac Surg. 2016 Sep;23(3):444-9. doi: 10.1093/icvts/ivw125. Epub 2016 May 25.

PMID:
27226401
48.

Characterization of Transporters in the Hepatic Uptake of TAK-475 M-I, a Squalene Synthase Inhibitor, in Rats and Humans.

Ebihara T, Takeuchi T, Moriya Y, Tagawa Y, Kondo T, Moriwaki T, Asahi S.

Drug Res (Stuttg). 2016 Jun;66(6):316-23. doi: 10.1055/s-0035-1569441. Epub 2016 Mar 24.

PMID:
27011383
49.

Postural deformities in Parkinson's disease -Mutual relationships among neck flexion, fore-bent, knee-bent and lateral-bent angles and correlations with clinical predictors.

Yoshii F, Moriya Y, Ohnuki T, Ryo M, Takahashi W.

J Clin Mov Disord. 2016 Jan 29;3:1. doi: 10.1186/s40734-016-0029-8. eCollection 2016.

50.

Identification of Enzyme Genes Using Chemical Structure Alignments of Substrate-Product Pairs.

Moriya Y, Yamada T, Okuda S, Nakagawa Z, Kotera M, Tokimatsu T, Kanehisa M, Goto S.

J Chem Inf Model. 2016 Mar 28;56(3):510-6. doi: 10.1021/acs.jcim.5b00216. Epub 2016 Feb 17.

PMID:
26822930

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