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Items: 1 to 50 of 146

1.

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.

Wanner N, Vornweg J, Combes A, Wilson S, Plappert J, Rafflenbeul G, Puelles VG, Rahman RU, Liwinski T, Lindner S, Grahammer F, Kretz O, Wlodek ME, Romano T, Moritz KM, Boerries M, Busch H, Bonn S, Little MH, Bechtel-Walz W, Huber TB.

J Am Soc Nephrol. 2018 Dec 5. pii: ASN.2018070736. doi: 10.1681/ASN.2018070736. [Epub ahead of print]

PMID:
30518531
2.

Impact of prenatal and postnatal maternal environment on nephron endowment, renal function and blood pressure in the Lewis polycystic kidney rat.

Ding A, Walton SL, Moritz KM, Phillips JK.

J Dev Orig Health Dis. 2018 Oct 2:1-10. doi: 10.1017/S2040174418000673. [Epub ahead of print]

PMID:
30274564
3.

Maternal exercise in rats upregulates the placental insulin-like growth factor system with diet- and sex-specific responses: minimal effects in mothers born growth restricted.

Mangwiro YTM, Cuffe JSM, Briffa JF, Mahizir D, Anevska K, Jefferies AJ, Hosseini S, Romano T, Moritz KM, Wlodek ME.

J Physiol. 2018 Dec;596(23):5947-5964. doi: 10.1113/JP275758. Epub 2018 Jul 26.

PMID:
29953638
4.

Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.

Akison LK, Kuo J, Reid N, Boyd RN, Moritz KM.

Alcohol Clin Exp Res. 2018 Sep;42(9):1591-1611. doi: 10.1111/acer.13817. Epub 2018 Jul 13. Review.

PMID:
29928762
5.

Angiotensin receptor blockade in juvenile male rat offspring: Implications for long-term cardio-renal health.

Walton SL, Mazzuca MQ, Tare M, Parkington HC, Wlodek ME, Moritz KM, Gallo LA.

Pharmacol Res. 2018 Aug;134:320-331. doi: 10.1016/j.phrs.2018.06.001. Epub 2018 Jun 2.

PMID:
29870806
6.

Transgenerational programming of nephron deficits and hypertension.

Briffa JF, Wlodek ME, Moritz KM.

Semin Cell Dev Biol. 2018 Jun 7. pii: S1084-9521(17)30447-0. doi: 10.1016/j.semcdb.2018.05.025. [Epub ahead of print] Review.

PMID:
29859996
7.

Prolonged prenatal hypoxia selectively disrupts collecting duct patterning and postnatal function in male mouse offspring.

Walton SL, Singh RR, Little MH, Bowles J, Li J, Moritz KM.

J Physiol. 2018 Dec;596(23):5873-5889. doi: 10.1113/JP275918. Epub 2018 Jul 5.

PMID:
29676801
8.

Uteroplacental insufficiency temporally exacerbates salt-induced hypertension associated with a reduced natriuretic response in male rat offspring.

Gallo LA, Walton SL, Mazzuca MQ, Tare M, Parkington HC, Wlodek ME, Moritz KM.

J Physiol. 2018 Dec;596(23):5859-5872. doi: 10.1113/JP275655. Epub 2018 Apr 25.

PMID:
29604087
9.

Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed mice.

Tan WS, Mullins TP, Flint M, Walton SL, Bielefeldt-Ohmann H, Carter DA, Gandhi MR, McDonald HR, Li J, Moritz KM, Reichelt ME, Gallo LA.

Am J Physiol Regul Integr Comp Physiol. 2018 Jun 1;314(6):R858-R869. doi: 10.1152/ajpregu.00357.2017. Epub 2018 Feb 14.

PMID:
29443547
10.

Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number.

Combes AN, Wilson S, Phipson B, Binnie BB, Ju A, Lawlor KT, Cebrian C, Walton SL, Smyth IM, Moritz KM, Kopan R, Oshlack A, Little MH.

Kidney Int. 2018 Mar;93(3):589-598. doi: 10.1016/j.kint.2017.09.015. Epub 2017 Dec 6.

PMID:
29217079
11.

Detrimental effects of alcohol exposure around conception: putative mechanisms.

Kalisch-Smith JI, Moritz KM.

Biochem Cell Biol. 2018 Apr;96(2):107-116. doi: 10.1139/bcb-2017-0133. Epub 2017 Nov 7. Review.

PMID:
29112458
12.

Maternal growth restriction and stress exposure in rats differentially alters expression of components of the placental glucocorticoid barrier and nutrient transporters.

Briffa JF, Hosseini SS, Tran M, Moritz KM, Cuffe JSM, Wlodek ME.

Placenta. 2017 Nov;59:30-38. doi: 10.1016/j.placenta.2017.09.006. Epub 2017 Sep 15.

PMID:
29108634
13.

Effects of periconceptional maternal alcohol intake and a postnatal high-fat diet on obesity and liver disease in male and female rat offspring.

Gårdebjer EM, Cuffe JSM, Ward LC, Steane S, Anderson ST, Dorey ES, Kalisch-Smith JI, Pantaleon M, Chong S, Yamada L, Wlodek ME, Bielefeldt-Ohmann H, Moritz KM.

Am J Physiol Endocrinol Metab. 2018 Oct 1;315(4):E694-E704. doi: 10.1152/ajpendo.00251.2017. Epub 2017 Oct 31.

PMID:
29089335
14.

Uteroplacental insufficiency in rats induces renal apoptosis and delays nephrogenesis completion.

Cuffe JSM, Briffa JF, Rosser S, Siebel AL, Romano T, Hryciw DH, Wlodek ME, Moritz KM.

Acta Physiol (Oxf). 2018 Mar;222(3). doi: 10.1111/apha.12982. Epub 2017 Nov 6.

PMID:
29047216
15.

The impact of periconceptional alcohol exposure on fat preference and gene expression in the mesolimbic reward pathway in adult rat offspring.

Dorey ES, Cullen CL, Lucia D, Mah KM, Manchadi MR, Muhlhausler BS, Moritz KM.

J Dev Orig Health Dis. 2018 Apr;9(2):223-231. doi: 10.1017/S2040174417000824. Epub 2017 Oct 17.

PMID:
29039297
16.

Prenatal hypoxia leads to hypertension, renal renin-angiotensin system activation and exacerbates salt-induced pathology in a sex-specific manner.

Walton SL, Bielefeldt-Ohmann H, Singh RR, Li J, Paravicini TM, Little MH, Moritz KM.

Sci Rep. 2017 Aug 15;7(1):8241. doi: 10.1038/s41598-017-08365-4.

17.

Sex differences in rat placental development: from pre-implantation to late gestation.

Kalisch-Smith JI, Simmons DG, Pantaleon M, Moritz KM.

Biol Sex Differ. 2017 May 16;8:17. doi: 10.1186/s13293-017-0138-6. eCollection 2017.

18.

Placental O-GlcNAc-transferase expression and interactions with the glucocorticoid receptor are sex specific and regulated by maternal corticosterone exposure in mice.

Pantaleon M, Steane SE, McMahon K, Cuffe JSM, Moritz KM.

Sci Rep. 2017 May 17;7(1):2017. doi: 10.1038/s41598-017-01666-8.

19.

Dexamethasone and sex regulate placental glucocorticoid receptor isoforms in mice.

Cuffe JSM, Saif Z, Perkins AV, Moritz KM, Clifton VL.

J Endocrinol. 2017 Aug;234(2):89-100. doi: 10.1530/JOE-17-0171. Epub 2017 May 10.

PMID:
28490442
20.

Maternal hypomagnesemia alters hippocampal NMDAR subunit expression and programs anxiety-like behaviour in adult offspring.

Schlegel RN, Spiers JG, Moritz KM, Cullen CL, Björkman ST, Paravicini TM.

Behav Brain Res. 2017 Jun 15;328:39-47. doi: 10.1016/j.bbr.2017.04.009. Epub 2017 Apr 4.

PMID:
28389335
21.

Uteroplacental insufficiency reduces rat plasma leptin concentrations and alters placental leptin transporters: ameliorated with enhanced milk intake and nutrition.

Briffa JF, O'Dowd R, Moritz KM, Romano T, Jedwab LR, McAinch AJ, Hryciw DH, Wlodek ME.

J Physiol. 2017 Jun 1;595(11):3389-3407. doi: 10.1113/JP273825. Epub 2017 Mar 29.

22.

Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage.

Singh RR, Sajeesh V, Booth LC, McArdle Z, May CN, Head GA, Moritz KM, Schlaich MP, Denton KM.

J Am Coll Cardiol. 2017 Feb 28;69(8):951-964. doi: 10.1016/j.jacc.2016.12.014.

23.

Review: Alterations in placental glycogen deposition in complicated pregnancies: Current preclinical and clinical evidence.

Akison LK, Nitert MD, Clifton VL, Moritz KM, Simmons DG.

Placenta. 2017 Jun;54:52-58. doi: 10.1016/j.placenta.2017.01.114. Epub 2017 Jan 11. Review.

PMID:
28117144
24.

Review: The role of multiple placental glucocorticoid receptor isoforms in adapting to the maternal environment and regulating fetal growth.

Clifton VL, Cuffe J, Moritz KM, Cole TJ, Fuller PJ, Lu NZ, Kumar S, Chong S, Saif Z.

Placenta. 2017 Jun;54:24-29. doi: 10.1016/j.placenta.2016.12.017. Epub 2016 Dec 19. Review.

PMID:
28017357
25.

Review: Sexual dimorphism in the formation, function and adaptation of the placenta.

Kalisch-Smith JI, Simmons DG, Dickinson H, Moritz KM.

Placenta. 2017 Jun;54:10-16. doi: 10.1016/j.placenta.2016.12.008. Epub 2016 Dec 8. Review.

PMID:
27979377
26.

Sex-Specific Metabolic Outcomes in Offspring of Female Rats Born Small or Exposed to Stress During Pregnancy.

Cheong JN, Cuffe JS, Jefferies AJ, Anevska K, Moritz KM, Wlodek ME.

Endocrinology. 2016 Nov;157(11):4104-4120. Epub 2016 Aug 29.

PMID:
27571133
27.

Prenatal corticosterone exposure programs sex-specific adrenal adaptations in mouse offspring.

Cuffe JS, Turton EL, Akison LK, Bielefeldt-Ohmann H, Moritz KM.

J Endocrinol. 2017 Jan;232(1):37-48. Epub 2016 Oct 17.

PMID:
27754933
28.

Alcohol exposure impairs trophoblast survival and alters subtype-specific gene expression in vitro.

Kalisch-Smith JI, Outhwaite JE, Simmons DG, Pantaleon M, Moritz KM.

Placenta. 2016 Oct;46:87-91. doi: 10.1016/j.placenta.2016.08.080. Epub 2016 Aug 25.

PMID:
27697226
29.

A review of fundamental principles for animal models of DOHaD research: an Australian perspective.

Dickinson H, Moss TJ, Gatford KL, Moritz KM, Akison L, Fullston T, Hryciw DH, Maloney CA, Morris MJ, Wooldridge AL, Schjenken JE, Robertson SA, Waddell BJ, Mark PJ, Wyrwoll CS, Ellery SJ, Thornburg KL, Muhlhausler BS, Morrison JL.

J Dev Orig Health Dis. 2016 Oct;7(5):449-472.

PMID:
27689313
30.

Lengths of nephron tubule segments and collecting ducts in the CD-1 mouse kidney: an ontogeny study.

Walton SL, Moritz KM, Bertram JF, Singh RR.

Am J Physiol Renal Physiol. 2016 Nov 1;311(5):F976-F983. doi: 10.1152/ajprenal.00435.2016. Epub 2016 Sep 21.

31.

Adrenal, metabolic and cardio-renal dysfunction develops after pregnancy in rats born small or stressed by physiological measurements during pregnancy.

Cheong JN, Cuffe JS, Jefferies AJ, Moritz KM, Wlodek ME.

J Physiol. 2016 Oct 15;594(20):6055-6068. doi: 10.1113/JP272212. Epub 2016 Jun 12.

32.

Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney.

Singh RR, Easton LK, Booth LC, Schlaich MP, Head GA, Moritz KM, Denton KM.

Sci Rep. 2016 May 26;6:26777. doi: 10.1038/srep26777.

33.

Maternal corticosterone exposure in the mouse programs sex-specific renal adaptations in the renin-angiotensin-aldosterone system in 6-month offspring.

Cuffe JS, Burgess DJ, O'Sullivan L, Singh RR, Moritz KM.

Physiol Rep. 2016 Apr;4(8). pii: e12754. doi: 10.14814/phy2.12754.

34.

The establishment of DOHaD working groups in Australia and New Zealand.

Prescott SL, Allen K, Armstrong K, Collins C, Dickinson H, Gardiner K, Jacka F, Jasoni C, Moore T, Moritz KM, Muhlhausler B, Siero W, Sim K, Nanan R, Saffery R, Singh G, Vickers MH, Craig JM.

J Dev Orig Health Dis. 2016 Oct;7(5):433-439. Epub 2016 Apr 27.

PMID:
27118250
35.

Maternal hypomagnesemia alters renal function but does not program changes in the cardiovascular physiology of adult offspring.

Schlegel RN, Moritz KM, Paravicini TM.

J Dev Orig Health Dis. 2016 Oct;7(5):473-480. Epub 2016 Mar 28.

PMID:
27019320
36.

Programming of maternal and offspring disease: impact of growth restriction, fetal sex and transmission across generations.

Cheong JN, Wlodek ME, Moritz KM, Cuffe JS.

J Physiol. 2016 Sep 1;594(17):4727-40. doi: 10.1113/JP271745. Epub 2016 Apr 24. Review.

37.

The role of maternal nutrition, metabolic function and the placenta in developmental programming of renal dysfunction.

Richter VF, Briffa JF, Moritz KM, Wlodek ME, Hryciw DH.

Clin Exp Pharmacol Physiol. 2016 Jan;43(1):135-41. doi: 10.1111/1440-1681.12505. Review.

PMID:
26475203
38.

Response to Letters Regarding Article, "Renal Dysfunction Is Associated With a Reduced Contribution of Nitric Oxide and Enhanced Vasoconstriction After a Congenital Renal Mass Reduction in Sheep".

Denton KM, Lankadeva YR, Singh RR, Parkington HC, Tare M, Moritz KM.

Circulation. 2015 Oct 13;132(15):e195. doi: 10.1161/CIRCULATIONAHA.115.016790. No abstract available.

PMID:
26459085
39.

Late gestational hypoxia and a postnatal high salt diet programs endothelial dysfunction and arterial stiffness in adult mouse offspring.

Walton SL, Singh RR, Tan T, Paravicini TM, Moritz KM.

J Physiol. 2016 Mar 1;594(5):1451-63. doi: 10.1113/JP271067. Epub 2015 Oct 12.

40.

Maternal obesity in females born small: Pregnancy complications and offspring disease risk.

Mahizir D, Briffa JF, Hryciw DH, Wadley GD, Moritz KM, Wlodek ME.

Mol Nutr Food Res. 2016 Jan;60(1):8-17. doi: 10.1002/mnfr.201500289. Epub 2015 Aug 6. Review.

PMID:
26173914
41.

Maternal hypomagnesemia causes placental abnormalities and fetal and postnatal mortality.

Schlegel RN, Cuffe JS, Moritz KM, Paravicini TM.

Placenta. 2015 Jul;36(7):750-8. doi: 10.1016/j.placenta.2015.03.011. Epub 2015 Apr 11.

PMID:
25924939
42.

Maternal alcohol intake around the time of conception causes glucose intolerance and insulin insensitivity in rat offspring, which is exacerbated by a postnatal high-fat diet.

Gårdebjer EM, Anderson ST, Pantaleon M, Wlodek ME, Moritz KM.

FASEB J. 2015 Jul;29(7):2690-701. doi: 10.1096/fj.14-268979. Epub 2015 Mar 2.

PMID:
25733565
43.

Excess prenatal corticosterone exposure results in albuminuria, sex-specific hypotension, and altered heart rate responses to restraint stress in aged adult mice.

O'Sullivan L, Cuffe JS, Koning A, Singh RR, Paravicini TM, Moritz KM.

Am J Physiol Renal Physiol. 2015 May 15;308(10):F1065-73. doi: 10.1152/ajprenal.00676.2014. Epub 2015 Feb 25.

44.

Differential mRNA expression and glucocorticoid-mediated regulation of TRPM6 and TRPM7 in the heart and kidney throughout murine pregnancy and development.

Cuffe JS, Steane S, Moritz KM, Paravicini TM.

PLoS One. 2015 Feb 18;10(2):e0117978. doi: 10.1371/journal.pone.0117978. eCollection 2015.

45.

Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling.

Wilkinson LJ, Neal CS, Singh RR, Sparrow DB, Kurniawan ND, Ju A, Grieve SM, Dunwoodie SL, Moritz KM, Little MH.

Kidney Int. 2015 May;87(5):975-83. doi: 10.1038/ki.2014.394. Epub 2015 Jan 14.

PMID:
25587709
46.

Renal dysfunction is associated with a reduced contribution of nitric oxide and enhanced vasoconstriction after a congenital renal mass reduction in sheep.

Lankadeva YR, Singh RR, Moritz KM, Parkington HC, Denton KM, Tare M.

Circulation. 2015 Jan 20;131(3):280-8. doi: 10.1161/CIRCULATIONAHA.114.013930. Epub 2014 Nov 4.

PMID:
25369804
47.

The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse.

Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM.

Placenta. 2014 Nov;35(11):953-61. doi: 10.1016/j.placenta.2014.09.004. Epub 2014 Sep 16.

PMID:
25249154
48.

Transgenerational left ventricular hypertrophy and hypertension in offspring after uteroplacental insufficiency in male rats.

Master JS, Zimanyi MA, Yin KV, Moritz KM, Gallo LA, Tran M, Wlodek ME, Black MJ.

Clin Exp Pharmacol Physiol. 2014 Nov;41(11):884-90. doi: 10.1111/1440-1681.12303.

PMID:
25199478
49.

Sex- and age-related differences in the chronic pressure-natriuresis relationship: role of the angiotensin type 2 receptor.

Mirabito KM, Hilliard LM, Kett MM, Brown RD, Booth SC, Widdop RE, Moritz KM, Evans RG, Denton KM.

Am J Physiol Renal Physiol. 2014 Oct 15;307(8):F901-7. doi: 10.1152/ajprenal.00288.2014. Epub 2014 Aug 27.

50.

Reduced sensitivity of the renal vasculature to angiotensin II in young rats: the role of the angiotensin type 2 receptor.

Brown RD, Hilliard LM, Mirabito KM, Wirth LC, Moritz KM, Evans RG, Denton KM.

Pediatr Res. 2014 Nov;76(5):448-52. doi: 10.1038/pr.2014.121. Epub 2014 Aug 13. Erratum in: Pediatr Res. 2015 Apr;77(4):606. Firth, Laura C [corrected to Wirth, Laura C].

PMID:
25119338

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