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Items: 30

1.

Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice.

Iannotti FA, Pagano E, Moriello AS, Alvino FG, Sorrentino NC, D'Orsi L, Gazzerro E, Capasso R, De Leonibus E, De Petrocellis L, Di Marzo V.

Br J Pharmacol. 2018 Aug 3. doi: 10.1111/bph.14460. [Epub ahead of print]

PMID:
30074247
2.

Iodine-Promoted Aromatization of p-Menthane-Type Phytocannabinoids.

Pollastro F, Caprioglio D, Marotta P, Moriello AS, De Petrocellis L, Taglialatela-Scafati O, Appendino G.

J Nat Prod. 2018 Mar 23;81(3):630-633. doi: 10.1021/acs.jnatprod.7b00946. Epub 2017 Dec 14.

PMID:
29240420
3.

Assay of TRPV1 Receptor Signaling.

Moriello AS, De Petrocellis L.

Methods Mol Biol. 2016;1412:65-76. doi: 10.1007/978-1-4939-3539-0_7.

PMID:
27245892
4.
5.

TRPA1 channels as targets for resveratrol and related stilbenoids.

Nalli M, Ortar G, Moriello AS, Morera E, Di Marzo V, De Petrocellis L.

Bioorg Med Chem Lett. 2016 Feb 1;26(3):899-902. doi: 10.1016/j.bmcl.2015.12.065. Epub 2015 Dec 19.

PMID:
26750258
6.

Modulation of the TRPV1 channel: current clinical trials and recent patents with focus on neurological conditions.

De Petrocellis L, Moriello AS.

Recent Pat CNS Drug Discov. 2013 Dec;8(3):180-204. Review.

PMID:
24330123
7.

Tetrahydro-β-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels.

Ortar G, De Petrocellis L, Moriello AS, Allarà M, Morera E, Nalli M, Di Marzo V.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):138-42. doi: 10.1016/j.bmcl.2012.10.137. Epub 2012 Nov 12.

PMID:
23206861
8.

Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channels.

Chianese G, Fattorusso E, Putra MY, Calcinai B, Bavestrello G, Moriello AS, De Petrocellis L, Di Marzo V, Taglialatela-Scafati O.

Mar Drugs. 2012 Nov 2;10(11):2435-47. doi: 10.3390/md10112435.

9.

Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds.

Ortar G, Morera L, Moriello AS, Morera E, Nalli M, Di Marzo V, De Petrocellis L.

Bioorg Med Chem Lett. 2012 May 15;22(10):3535-9. doi: 10.1016/j.bmcl.2012.03.055. Epub 2012 Mar 20.

PMID:
22503249
10.

Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators.

Morera E, De Petrocellis L, Morera L, Moriello AS, Nalli M, Di Marzo V, Ortar G.

Bioorg Med Chem Lett. 2012 Feb 15;22(4):1674-7. doi: 10.1016/j.bmcl.2011.12.113. Epub 2011 Dec 31.

PMID:
22257892
11.

Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation.

De Petrocellis L, Orlando P, Moriello AS, Aviello G, Stott C, Izzo AA, Di Marzo V.

Acta Physiol (Oxf). 2012 Feb;204(2):255-66. doi: 10.1111/j.1748-1716.2011.02338.x. Epub 2011 Aug 12.

PMID:
21726418
12.

N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity.

De Petrocellis L, Guida F, Moriello AS, De Chiaro M, Piscitelli F, de Novellis V, Maione S, Di Marzo V.

Pharmacol Res. 2011 Apr;63(4):294-9. doi: 10.1016/j.phrs.2010.12.019. Epub 2011 Jan 5.

PMID:
21215315
13.

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes.

De Petrocellis L, Ligresti A, Moriello AS, Allarà M, Bisogno T, Petrosino S, Stott CG, Di Marzo V.

Br J Pharmacol. 2011 Aug;163(7):1479-94. doi: 10.1111/j.1476-5381.2010.01166.x.

14.

Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter.

Ligresti A, De Petrocellis L, Hernán Pérez de la Ossa D, Aberturas R, Cristino L, Moriello AS, Finizio A, Gil ME, Torres AI, Molpeceres J, Di Marzo V.

PLoS One. 2010 Apr 22;5(4):e10239. doi: 10.1371/journal.pone.0010239.

15.

(-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels.

Ortar G, De Petrocellis L, Morera L, Moriello AS, Orlando P, Morera E, Nalli M, Di Marzo V.

Bioorg Med Chem Lett. 2010 May 1;20(9):2729-32. doi: 10.1016/j.bmcl.2010.03.076. Epub 2010 Mar 25.

PMID:
20378345
16.

Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands.

Morera E, De Petrocellis L, Morera L, Moriello AS, Ligresti A, Nalli M, Woodward DF, Di Marzo V, Ortar G.

Bioorg Med Chem Lett. 2009 Dec 1;19(23):6806-9. doi: 10.1016/j.bmcl.2009.09.033. Epub 2009 Oct 20.

PMID:
19875281
17.

Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors.

Marini P, Moriello AS, Cristino L, Palmery M, De Petrocellis L, Di Marzo V.

Biochim Biophys Acta. 2009 Jul;1793(7):1289-303. doi: 10.1016/j.bbamcr.2009.05.002. Epub 2009 May 13.

18.

Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens.

Bassoli A, Borgonovo G, Caimi S, Scaglioni L, Morini G, Moriello AS, Di Marzo V, De Petrocellis L.

Bioorg Med Chem. 2009 Feb 15;17(4):1636-9. doi: 10.1016/j.bmc.2008.12.057. Epub 2008 Dec 30.

PMID:
19162486
19.

Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells.

De Petrocellis L, Marini P, Matias I, Moriello AS, Starowicz K, Cristino L, Nigam S, Di Marzo V.

Exp Cell Res. 2007 Aug 15;313(14):2993-3004. Epub 2007 May 18.

PMID:
17585904
20.

Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation.

Ortar G, Cascio MG, Moriello AS, Camalli M, Morera E, Nalli M, Di Marzo V.

Eur J Med Chem. 2008 Jan;43(1):62-72. Epub 2007 Mar 19.

PMID:
17452063
21.

Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids.

De Petrocellis L, Starowicz K, Moriello AS, Vivese M, Orlando P, Di Marzo V.

Exp Cell Res. 2007 May 15;313(9):1911-20. Epub 2007 Jan 18.

PMID:
17428469
22.

Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors.

Maione S, De Petrocellis L, de Novellis V, Moriello AS, Petrosino S, Palazzo E, Rossi FS, Woodward DF, Di Marzo V.

Br J Pharmacol. 2007 Mar;150(6):766-81. Epub 2007 Feb 5.

23.

Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration.

Matias I, Wang JW, Moriello AS, Nieves A, Woodward DF, Di Marzo V.

Prostaglandins Leukot Essent Fatty Acids. 2006 Dec;75(6):413-8. Epub 2006 Oct 2.

PMID:
17011761
24.

Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.

Ligresti A, Moriello AS, Starowicz K, Matias I, Pisanti S, De Petrocellis L, Laezza C, Portella G, Bifulco M, Di Marzo V.

J Pharmacol Exp Ther. 2006 Sep;318(3):1375-87. Epub 2006 May 25.

25.

Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity.

Appendino G, Minassi A, Berton L, Moriello AS, Cascio MG, De Petrocellis L, Di Marzo V.

J Med Chem. 2006 Apr 6;49(7):2333-8.

PMID:
16570929
26.

First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands.

Appendino G, Cascio MG, Bacchiega S, Moriello AS, Minassi A, Thomas A, Ross R, Pertwee R, De Petrocellis L, Di Marzo V.

FEBS Lett. 2006 Jan 23;580(2):568-74. Epub 2005 Dec 29.

27.

The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination.

Appendino G, Daddario N, Minassi A, Moriello AS, De Petrocellis L, Di Marzo V.

J Med Chem. 2005 Jul 14;48(14):4663-9.

PMID:
16000002
28.

Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential.

Appendino G, De Petrocellis L, Trevisani M, Minassi A, Daddario N, Moriello AS, Gazzieri D, Ligresti A, Campi B, Fontana G, Pinna C, Geppetti P, Di Marzo V.

J Pharmacol Exp Ther. 2005 Feb;312(2):561-70. Epub 2004 Sep 8.

29.

Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels.

De Petrocellis L, Chu CJ, Moriello AS, Kellner JC, Walker JM, Di Marzo V.

Br J Pharmacol. 2004 Sep;143(2):251-6. Epub 2004 Aug 2.

30.

Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.

Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, Moriello AS, Davis JB, Mechoulam R, Di Marzo V.

Br J Pharmacol. 2001 Oct;134(4):845-52.

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