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Items: 41


Novel multi-component vaccine approaches for Burkholderia pseudomallei.

Morici L, Torres AG, Titball RW.

Clin Exp Immunol. 2019 May;196(2):178-188. doi: 10.1111/cei.13286. Epub 2019 Apr 8. Review.


Intradermal vaccination with a Pseudomonas aeruginosa vaccine adjuvanted with a mutant bacterial ADP-ribosylating enterotoxin protects against acute pneumonia.

Baker SM, Pociask D, Clements JD, McLachlan JB, Morici LA.

Vaccine. 2019 Feb 4;37(6):808-816. doi: 10.1016/j.vaccine.2018.12.053. Epub 2019 Jan 9.


A Burkholderia pseudomallei Outer Membrane Vesicle Vaccine Provides Cross Protection against Inhalational Glanders in Mice and Non-Human Primates.

Baker SM, Davitt CJH, Motyka N, Kikendall NL, Russell-Lodrigue K, Roy CJ, Morici LA.

Vaccines (Basel). 2017 Dec 9;5(4). pii: E49. doi: 10.3390/vaccines5040049.


Immunomodulatory effects of tick saliva on dermal cells exposed to Borrelia burgdorferi, the agent of Lyme disease.

Scholl DC, Embers ME, Caskey JR, Kaushal D, Mather TN, Buck WR, Morici LA, Philipp MT.

Parasit Vectors. 2016 Jul 8;9(1):394. doi: 10.1186/s13071-016-1638-7.


A novel approach for emerging and antibiotic resistant infections: Innate defense regulators as an agnostic therapy.

North JR, Takenaka S, Rozek A, Kielczewska A, Opal S, Morici LA, Finlay BB, Schaber CJ, Straube R, Donini O.

J Biotechnol. 2016 May 20;226:24-34. doi: 10.1016/j.jbiotec.2016.03.032. Epub 2016 Mar 23.


Consensus on the development of vaccines against naturally acquired melioidosis.

Limmathurotsakul D, Funnell SG, Torres AG, Morici LA, Brett PJ, Dunachie S, Atkins T, Altmann DM, Bancroft G, Peacock SJ; Steering Group on Melioidosis Vaccine Development.

Emerg Infect Dis. 2015 Jun;21(6). doi: 10.3201/eid2106.141480.


Protection of non-human primates against glanders with a gold nanoparticle glycoconjugate vaccine.

Torres AG, Gregory AE, Hatcher CL, Vinet-Oliphant H, Morici LA, Titball RW, Roy CJ.

Vaccine. 2015 Jan 29;33(5):686-92. doi: 10.1016/j.vaccine.2014.11.057. Epub 2014 Dec 19.


Microbial contamination in next generation sequencing: implications for sequence-based analysis of clinical samples.

Strong MJ, Xu G, Morici L, Splinter Bon-Durant S, Baddoo M, Lin Z, Fewell C, Taylor CM, Flemington EK.

PLoS Pathog. 2014 Nov 20;10(11):e1004437. doi: 10.1371/journal.ppat.1004437. eCollection 2014 Nov.


Evaluation of a Burkholderia pseudomallei Outer Membrane Vesicle Vaccine in Nonhuman Primates.

Petersen H, Nieves W, Russell-Lodrigue K, Roy CJ, Morici LA.

Procedia Vaccinol. 2014 Jan 1;8:38-42.


Vaccination with a single CD4 T cell peptide epitope from a Salmonella type III-secreted effector protein provides protection against lethal infection.

Kurtz JR, Petersen HE, Frederick DR, Morici LA, McLachlan JB.

Infect Immun. 2014 Jun;82(6):2424-33. doi: 10.1128/IAI.00052-14. Epub 2014 Mar 31.


A Burkholderia pseudomallei outer membrane vesicle vaccine provides protection against lethal sepsis.

Nieves W, Petersen H, Judy BM, Blumentritt CA, Russell-Lodrigue K, Roy CJ, Torres AG, Morici LA.

Clin Vaccine Immunol. 2014 May;21(5):747-54. doi: 10.1128/CVI.00119-14. Epub 2014 Mar 26.


PGE(2) suppression of innate immunity during mucosal bacterial infection.

Agard M, Asakrah S, Morici LA.

Front Cell Infect Microbiol. 2013 Aug 21;3:45. doi: 10.3389/fcimb.2013.00045. eCollection 2013. Review.


The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: a proposal for an evolutionary driving force.

Bocedi A, Fabrini R, Farrotti A, Stella L, Ketterman AJ, Pedersen JZ, Allocati N, Lau PC, Grosse S, Eltis LD, Ruzzini A, Edwards TE, Morici L, Del Grosso E, Guidoni L, Bovi D, Lo Bello M, Federici G, Parker MW, Board PG, Ricci G.

J Biol Chem. 2013 Aug 23;288(34):24936-47. doi: 10.1074/jbc.M113.476135. Epub 2013 Jul 3.


Flavonoid naringenin: a potential immunomodulator for Chlamydia trachomatis inflammation.

Yilma AN, Singh SR, Morici L, Dennis VA.

Mediators Inflamm. 2013;2013:102457. doi: 10.1155/2013/102457. Epub 2013 May 23.


Post-exposure therapeutic efficacy of COX-2 inhibition against Burkholderia pseudomallei.

Asakrah S, Nieves W, Mahdi Z, Agard M, Zea AH, Roy CJ, Morici LA.

PLoS Negl Trop Dis. 2013 May 9;7(5):e2212. doi: 10.1371/journal.pntd.0002212. Print 2013.


Strain sensitivity and superconducting properties of Nb3Sn from first principles calculations.

De Marzi G, Morici L, Muzzi L, della Corte A, Nardelli MB.

J Phys Condens Matter. 2013 Apr 3;25(13):135702. doi: 10.1088/0953-8984/25/13/135702. Epub 2013 Mar 11.


Nasal carriage of methicillin-resistant Staphylococcus aureus among students at a Louisiana medical university.

Bellows C, Smith A, Wheeler J, Morici L.

Braz J Infect Dis. 2013 Jan-Feb;17(1):118-9. doi: 10.1016/j.bjid.2012.08.018. Epub 2013 Jan 3. No abstract available.


Different patterns of expression and of IL-10 modulation of inflammatory mediators from macrophages of Lyme disease-resistant and -susceptible mice.

Gautam A, Dixit S, Embers M, Gautam R, Philipp MT, Singh SR, Morici L, Dennis VA.

PLoS One. 2012;7(9):e43860. Epub 2012 Sep 14.


Erythrocyte glutathione transferase: a novel biomarker to check environmental pollution hazardous for humans.

Fabrini R, Bocedi A, Del Grosso E, Morici L, Federici G, Palleschi A, Ricci G.

Biochem Biophys Res Commun. 2012 Sep 14;426(1):71-5. doi: 10.1016/j.bbrc.2012.08.037. Epub 2012 Aug 14.


Microglia activation by SIV-infected macrophages: alterations in morphology and cytokine secretion.

Renner NA, Sansing HA, Morici LA, Inglis FM, Lackner AA, MacLean AG.

J Neurovirol. 2012 Jun;18(3):213-21. doi: 10.1007/s13365-012-0100-7. Epub 2012 Apr 26.


Histologic and biomechanical evaluation of biologic meshes following colonization with Pseudomonas aeruginosa.

Bellows CF, Wheatley B, Moroz K, Rosales S, Morici LA.

J Surg Res. 2012 Jun 1;175(1):e35-42. doi: 10.1016/j.jss.2011.10.044. Epub 2011 Nov 21.


The stress-response factor SigH modulates the interaction between Mycobacterium tuberculosis and host phagocytes.

Dutta NK, Mehra S, Martinez AN, Alvarez X, Renner NA, Morici LA, Pahar B, Maclean AG, Lackner AA, Kaushal D.

PLoS One. 2012;7(1):e28958. doi: 10.1371/journal.pone.0028958. Epub 2012 Jan 3.


Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation.

Gautam A, Dixit S, Philipp MT, Singh SR, Morici LA, Kaushal D, Dennis VA.

Infect Immun. 2011 Dec;79(12):4876-92. doi: 10.1128/IAI.05451-11. Epub 2011 Sep 26.


A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection.

Nieves W, Asakrah S, Qazi O, Brown KA, Kurtz J, Aucoin DP, McLachlan JB, Roy CJ, Morici LA.

Vaccine. 2011 Oct 26;29(46):8381-9. doi: 10.1016/j.vaccine.2011.08.058. Epub 2011 Aug 24.


The effect of bacterial infection on the biomechanical properties of biological mesh in a rat model.

Bellows CF, Wheatley BM, Moroz K, Rosales SC, Morici LA.

PLoS One. 2011;6(6):e21228. doi: 10.1371/journal.pone.0021228. Epub 2011 Jun 16.


Early divergent host responses in SHIVsf162P3 and SIVmac251 infected macaques correlate with control of viremia.

Xu H, Wang X, Morici LA, Pahar B, Veazey RS.

PLoS One. 2011 Mar 25;6(3):e17965. doi: 10.1371/journal.pone.0017965.


Mucosal vaccines for biodefense.

Mantis NJ, Morici LA, Roy CJ.

Curr Top Microbiol Immunol. 2012;354:181-95. doi: 10.1007/82_2011_122. Review.


Immunospecific responses to bacterial elongation factor Tu during Burkholderia infection and immunization.

Nieves W, Heang J, Asakrah S, Höner zu Bentrup K, Roy CJ, Morici LA.

PLoS One. 2010 Dec 17;5(12):e14361. doi: 10.1371/journal.pone.0014361.


Transcriptional and proteomic responses of Pseudomonas aeruginosa PAO1 to spaceflight conditions involve Hfq regulation and reveal a role for oxygen.

Crabbé A, Schurr MJ, Monsieurs P, Morici L, Schurr J, Wilson JW, Ott CM, Tsaprailis G, Pierson DL, Stefanyshyn-Piper H, Nickerson CA.

Appl Environ Microbiol. 2011 Feb;77(4):1221-30. doi: 10.1128/AEM.01582-10. Epub 2010 Dec 17.


Differential susceptibility of inbred mouse strains to Burkholderia thailandensis aerosol infection.

Morici LA, Heang J, Tate T, Didier PJ, Roy CJ.

Microb Pathog. 2010 Jan;48(1):9-17. doi: 10.1016/j.micpath.2009.10.004. Epub 2009 Oct 21.


Possible role of glial cells in the onset and progression of Lyme neuroborreliosis.

Ramesh G, Borda JT, Gill A, Ribka EP, Morici LA, Mottram P, Martin DS, Jacobs MB, Didier PJ, Philipp MT.

J Neuroinflammation. 2009 Aug 25;6:23. doi: 10.1186/1742-2094-6-23.


Media ion composition controls regulatory and virulence response of Salmonella in spaceflight.

Wilson JW, Ott CM, Quick L, Davis R, Höner zu Bentrup K, Crabbé A, Richter E, Sarker S, Barrila J, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Shah M, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, CdeBaca A, Narayan S, Benjamin J, Goulart C, Rupert M, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Porter MD, Pierson DL, Smith SM, Mergeay M, Leys N, Stefanyshyn-Piper HM, Gorie D, Nickerson CA.

PLoS One. 2008;3(12):e3923. doi: 10.1371/journal.pone.0003923. Epub 2008 Dec 12.


Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq.

Wilson JW, Ott CM, Höner zu Bentrup K, Ramamurthy R, Quick L, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Fernandez D, Richter E, Shah M, Kilcoyne M, Joshi L, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, Goulart C, Rupert M, Stodieck L, Stafford P, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Allen P, Baker-Coleman C, Hammond T, Vogel J, Nelson R, Pierson DL, Stefanyshyn-Piper HM, Nickerson CA.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16299-304. Epub 2007 Sep 27.


Enhanced mortality despite control of lung infection in mice aerogenically infected with a Mycobacterium tuberculosis mce1 operon mutant.

Lima P, Sidders B, Morici L, Reader R, Senaratne R, Casali N, Riley LW.

Microbes Infect. 2007 Sep;9(11):1285-90. Epub 2007 Jun 9.


Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner.

Morici LA, Carterson AJ, Wagner VE, Frisk A, Schurr JR, Höner zu Bentrup K, Hassett DJ, Iglewski BH, Sauer K, Schurr MJ.

J Bacteriol. 2007 Nov;189(21):7752-64. Epub 2007 Aug 31.


Accelerated immunopathological response of mice infected with Mycobacterium tuberculosis disrupted in the mce1 operon negative transcriptional regulator.

Uchida Y, Casali N, White A, Morici L, Kendall LV, Riley LW.

Cell Microbiol. 2007 May;9(5):1275-83. Epub 2007 Jan 11.


TRAIL-R as a negative regulator of innate immune cell responses.

Diehl GE, Yue HH, Hsieh K, Kuang AA, Ho M, Morici LA, Lenz LL, Cado D, Riley LW, Winoto A.

Immunity. 2004 Dec;21(6):877-89.


The transcriptional regulator AlgR controls cyanide production in Pseudomonas aeruginosa.

Carterson AJ, Morici LA, Jackson DW, Frisk A, Lizewski SE, Jupiter R, Simpson K, Kunz DA, Davis SH, Schurr JR, Hassett DJ, Schurr MJ.

J Bacteriol. 2004 Oct;186(20):6837-44.


Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon.

Shimono N, Morici L, Casali N, Cantrell S, Sidders B, Ehrt S, Riley LW.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15918-23. Epub 2003 Dec 8.


Hyperlipidemia and reproductive failure in captive-reared alligators: vitamin E, vitamin A, plasma lipids, fatty acids, and steroid hormones.

Lance VA, Morici LA, Elsey RM, Lund ED, Place AR.

Comp Biochem Physiol B Biochem Mol Biol. 2001 Feb;128(2):285-94.


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