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Items: 16


RbpA relaxes promoter selectivity of M. tuberculosis RNA polymerase.

Sudalaiyadum Perumal A, Vishwakarma RK, Hu Y, Morichaud Z, Brodolin K.

Nucleic Acids Res. 2018 Nov 2;46(19):10106-10118. doi: 10.1093/nar/gky714.


Single-molecule analysis reveals the mechanism of transcription activation in M. tuberculosis.

Vishwakarma RK, Cao AM, Morichaud Z, Perumal AS, Margeat E, Brodolin K.

Sci Adv. 2018 May 23;4(5):eaao5498. doi: 10.1126/sciadv.aao5498. eCollection 2018 May.


Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria.

Dulin D, Bauer DLV, Malinen AM, Bakermans JJW, Kaller M, Morichaud Z, Petushkov I, Depken M, Brodolin K, Kulbachinskiy A, Kapanidis AN.

Nat Commun. 2018 Apr 16;9(1):1478. doi: 10.1038/s41467-018-03902-9.


Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes.

Duchi D, Gryte K, Robb NC, Morichaud Z, Sheppard C, Brodolin K, Wigneshweraraj S, Kapanidis AN.

Nucleic Acids Res. 2018 Jan 25;46(2):677-688. doi: 10.1093/nar/gkx1146.


RNA Polymerase Pausing during Initial Transcription.

Duchi D, Bauer DL, Fernandez L, Evans G, Robb N, Hwang LC, Gryte K, Tomescu A, Zawadzki P, Morichaud Z, Brodolin K, Kapanidis AN.

Mol Cell. 2016 Sep 15;63(6):939-50. doi: 10.1016/j.molcel.2016.08.011. Epub 2016 Sep 8.


Regions 1.2 and 3.2 of the RNA Polymerase σ Subunit Promote DNA Melting and Attenuate Action of the Antibiotic Lipiarmycin.

Morichaud Z, Chaloin L, Brodolin K.

J Mol Biol. 2016 Jan 29;428(2 Pt B):463-76. doi: 10.1016/j.jmb.2015.12.017. Epub 2015 Dec 24.


Mycobacterium RbpA cooperates with the stress-response σB subunit of RNA polymerase in promoter DNA unwinding.

Hu Y, Morichaud Z, Perumal AS, Roquet-Baneres F, Brodolin K.

Nucleic Acids Res. 2014;42(16):10399-408. doi: 10.1093/nar/gku742. Epub 2014 Aug 13.


Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the σ A-containing RNA polymerase holoenzyme.

Hu Y, Morichaud Z, Chen S, Leonetti JP, Brodolin K.

Nucleic Acids Res. 2012 Aug;40(14):6547-57. doi: 10.1093/nar/gks346. Epub 2012 May 8.


The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts.

Vives V, Laurin M, Cres G, Larrousse P, Morichaud Z, Noel D, Côté JF, Blangy A.

J Bone Miner Res. 2011 May;26(5):1099-110. doi: 10.1002/jbmr.282.


Resistance to rifampicin: at the crossroads between ecological, genomic and medical concerns.

Tupin A, Gualtieri M, Roquet-Banères F, Morichaud Z, Brodolin K, Leonetti JP.

Int J Antimicrob Agents. 2010 Jun;35(6):519-23. doi: 10.1016/j.ijantimicag.2009.12.017. Epub 2010 Feb 24. Review.


The conserved N-terminal basic residues and zinc-finger motifs of HIV-1 nucleocapsid restrict the viral cDNA synthesis during virus formation and maturation.

Didierlaurent L, Houzet L, Morichaud Z, Darlix JL, Mougel M.

Nucleic Acids Res. 2008 Aug;36(14):4745-53. doi: 10.1093/nar/gkn474. Epub 2008 Jul 18.


Nucleocapsid mutations turn HIV-1 into a DNA-containing virus.

Houzet L, Morichaud Z, Didierlaurent L, Muriaux D, Darlix JL, Mougel M.

Nucleic Acids Res. 2008 Apr;36(7):2311-9. doi: 10.1093/nar/gkn069. Epub 2008 Feb 22.


HIV controls the selective packaging of genomic, spliced viral and cellular RNAs into virions through different mechanisms.

Houzet L, Paillart JC, Smagulova F, Maurel S, Morichaud Z, Marquet R, Mougel M.

Nucleic Acids Res. 2007;35(8):2695-704. Epub 2007 Apr 10.


Intracellular assembly and budding of the Murine Leukemia Virus in infected cells.

Houzet L, Gay B, Morichaud Z, Briant L, Mougel M.

Retrovirology. 2006 Feb 10;3:12.


The highly structured encapsidation signal of MuLV RNA is involved in the nuclear export of its unspliced RNA.

Smagulova F, Maurel S, Morichaud Z, Devaux C, Mougel M, Houzet L.

J Mol Biol. 2005 Dec 16;354(5):1118-28. Epub 2005 Nov 2.


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