Sort by
Items per page

Send to

Choose Destination

Search results

Items: 43


The UBIAD1 prenyltransferase links menaquinone-4 [corrected] synthesis to cholesterol metabolic enzymes.

Nickerson ML, Bosley AD, Weiss JS, Kostiha BN, Hirota Y, Brandt W, Esposito D, Kinoshita S, Wessjohann L, Morham SG, Andresson T, Kruth HS, Okano T, Dean M.

Hum Mutat. 2013 Feb;34(2):317-29. doi: 10.1002/humu.22230. Epub 2012 Nov 27. Erratum in: Hum Mutat. 2013 Jul;34(7):1046.


Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection.

Brown C, Morham SG, Walsh D, Naghavi MH.

J Mol Biol. 2011 Jul 29;410(5):761-77. doi: 10.1016/j.jmb.2011.03.076.


PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1.

Henning MS, Stiedl P, Barry DS, McMahon R, Morham SG, Walsh D, Naghavi MH.

Virology. 2011 Jul 5;415(2):114-21. doi: 10.1016/j.virol.2011.04.006. Epub 2011 May 6.


The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination.

Demorest ZL, MacDuff DA, Brown WL, Morham SG, Parise LV, Harris RS.

PLoS One. 2010 Jul 20;5(7):e11660. doi: 10.1371/journal.pone.0011660.


PDZD8 is a novel Gag-interacting factor that promotes retroviral infection.

Henning MS, Morham SG, Goff SP, Naghavi MH.

J Virol. 2010 Sep;84(17):8990-5. doi: 10.1128/JVI.00843-10. Epub 2010 Jun 23.


Biochemical analyses of human IST1 and its function in cytokinesis.

Bajorek M, Morita E, Skalicky JJ, Morham SG, Babst M, Sundquist WI.

Mol Biol Cell. 2009 Mar;20(5):1360-73. doi: 10.1091/mbc.E08-05-0475. Epub 2009 Jan 7.


Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.

Morita E, Sandrin V, Chung HY, Morham SG, Gygi SP, Rodesch CK, Sundquist WI.

EMBO J. 2007 Oct 3;26(19):4215-27. Epub 2007 Sep 13. Erratum in: EMBO J. 2012 Jul 18;31(14):3228.


Sex differences in inflammation and inflammatory pain in cyclooxygenase-deficient mice.

Chillingworth NL, Morham SG, Donaldson LF.

Am J Physiol Regul Integr Comp Physiol. 2006 Aug;291(2):R327-34. Epub 2006 Mar 23.


E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation.

Goulet JL, Pace AJ, Key ML, Byrum RS, Nguyen M, Tilley SL, Morham SG, Langenbach R, Stock JL, McNeish JD, Smithies O, Coffman TM, Koller BH.

J Immunol. 2004 Jul 15;173(2):1321-6.


The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding.

Stuchell MD, Garrus JE, Müller B, Stray KM, Ghaffarian S, McKinnon R, Kräusslich HG, Morham SG, Sundquist WI.

J Biol Chem. 2004 Aug 20;279(34):36059-71. Epub 2004 Jun 23.


The protein network of HIV budding.

von Schwedler UK, Stuchell M, Müller B, Ward DM, Chung HY, Morita E, Wang HE, Davis T, He GP, Cimbora DM, Scott A, Kräusslich HG, Kaplan J, Morham SG, Sundquist WI.

Cell. 2003 Sep 19;114(6):701-13.


HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein.

Pornillos O, Higginson DS, Stray KM, Fisher RD, Garrus JE, Payne M, He GP, Wang HE, Morham SG, Sundquist WI.

J Cell Biol. 2003 Aug 4;162(3):425-34.


ZNF202 is inversely regulated with its target genes ABCA1 and apoE during macrophage differentiation and foam cell formation.

Langmann T, Schumacher C, Morham SG, Honer C, Heimerl S, Moehle C, Schmitz G.

J Lipid Res. 2003 May;44(5):968-77. Epub 2003 Mar 1.


Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.

Tiano HF, Loftin CD, Akunda J, Lee CA, Spalding J, Sessoms A, Dunson DB, Rogan EG, Morham SG, Smart RC, Langenbach R.

Cancer Res. 2002 Jun 15;62(12):3395-401.


COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice.

Sigthorsson G, Simpson RJ, Walley M, Anthony A, Foster R, Hotz-Behoftsitz C, Palizban A, Pombo J, Watts J, Morham SG, Bjarnason I.

Gastroenterology. 2002 Jun;122(7):1913-23.


A genetically clamped renin transgene for the induction of hypertension.

Caron KM, James LR, Kim HS, Morham SG, Sequeira Lopez ML, Gomez RA, Reudelhuber TL, Smithies O.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8248-52. Epub 2002 May 28.


Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding.

Garrus JE, von Schwedler UK, Pornillos OW, Morham SG, Zavitz KH, Wang HE, Wettstein DA, Stray KM, Côté M, Rich RL, Myszka DG, Sundquist WI.

Cell. 2001 Oct 5;107(1):55-65.


Cyclooxygenase-2 mediates the febrile response of mice to interleukin-1beta.

Li S, Ballou LR, Morham SG, Blatteis CM.

Brain Res. 2001 Aug 10;910(1-2):163-73.


Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis.

Zhang X, Morham SG, Langenbach R, Young DA, Xing L, Boyce BF, Puzas EJ, Rosier RN, O'Keefe RJ, Schwarz EM.

J Bone Miner Res. 2001 Apr;16(4):660-70.


Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2.

Loftin CD, Trivedi DB, Tiano HF, Clark JA, Lee CA, Epstein JA, Morham SG, Breyer MD, Nguyen M, Hawkins BM, Goulet JL, Smithies O, Koller BH, Langenbach R.

Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1059-64. Epub 2001 Jan 23.


The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis.

Myers LK, Kang AH, Postlethwaite AE, Rosloniec EF, Morham SG, Shlopov BV, Goorha S, Ballou LR.

Arthritis Rheum. 2000 Dec;43(12):2687-93.


Postnatal development and progression of renal dysplasia in cyclooxygenase-2 null mice.

Norwood VF, Morham SG, Smithies O.

Kidney Int. 2000 Dec;58(6):2291-300.


Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.

Chulada PC, Thompson MB, Mahler JF, Doyle CM, Gaul BW, Lee C, Tiano HF, Morham SG, Smithies O, Langenbach R.

Cancer Res. 2000 Sep 1;60(17):4705-8.


Prostaglandin G/H synthase-2 is required for maximal formation of osteoclast-like cells in culture.

Okada Y, Lorenzo JA, Freeman AM, Tomita M, Morham SG, Raisz LG, Pilbeam CC.

J Clin Invest. 2000 Mar;105(6):823-32.


Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2.

Morteau O, Morham SG, Sellon R, Dieleman LA, Langenbach R, Smithies O, Sartor RB.

J Clin Invest. 2000 Feb;105(4):469-78.


Lack of cyclooxygenase-2 inhibits growth of teratocarcinomas in mice.

Zhang X, Morham SG, Langenbach R, Baggs RB, Young DA.

Exp Cell Res. 2000 Feb 1;254(2):232-40.


Cyclooxygenase-2 contributes to functional hyperemia in whisker-barrel cortex.

Niwa K, Araki E, Morham SG, Ross ME, Iadecola C.

J Neurosci. 2000 Jan 15;20(2):763-70.


Genetic evidence for distinct roles of COX-1 and COX-2 in the immediate and delayed phases of prostaglandin synthesis in mast cells.

Reddy ST, Tiano HF, Langenbach R, Morham SG, Herschman HR.

Biochem Biophys Res Commun. 1999 Nov;265(1):205-10.


Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta.

Davis BJ, Lennard DE, Lee CA, Tiano HF, Morham SG, Wetsel WC, Langenbach R.

Endocrinology. 1999 Jun;140(6):2685-95.


The febrile response to lipopolysaccharide is blocked in cyclooxygenase-2(-/-), but not in cyclooxygenase-1(-/-) mice.

Li S, Wang Y, Matsumura K, Ballou LR, Morham SG, Blatteis CM.

Brain Res. 1999 Apr 17;825(1-2):86-94.


Compensatory prostaglandin E2 biosynthesis in cyclooxygenase 1 or 2 null cells.

Kirtikara K, Morham SG, Raghow R, Laulederkind SJ, Kanekura T, Goorha S, Ballou LR.

J Exp Med. 1998 Feb 16;187(4):517-23.


Characterization of prostaglandin H synthase 2 deficient mice and implications for mechanisms of NSAID action.

Morham SG, Langenbach R, Mahler J, Smithies O.

Adv Exp Med Biol. 1997;407:131-8. No abstract available.


Disruption of the mouse cyclooxygenase 1 gene. Characteristics of the mutant and areas of future study.

Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, Mahler JF, Davis BJ, Lee CA.

Adv Exp Med Biol. 1997;407:87-92.


Targeted disruption of the mouse topoisomerase I gene by camptothecin selection.

Morham SG, Kluckman KD, Voulomanos N, Smithies O.

Mol Cell Biol. 1996 Dec;16(12):6804-9.


Disruption of cyclooxygenase genes in mice.

Mahler JF, Davis BJ, Morham SG, Langenbach R.

Toxicol Pathol. 1996 Nov-Dec;24(6):717-9. Review. No abstract available.


Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.

Bozza PT, Payne JL, Morham SG, Langenbach R, Smithies O, Weller PF.

Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):11091-6.


Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, Mahler JF, Lee CA, Goulding EH, Kluckman KD, Kim HS, Smithies O.

Cell. 1995 Nov 3;83(3):483-92.


Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

Morham SG, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jennette JC, Mahler JF, Kluckman KD, Ledford A, Lee CA, Smithies O.

Cell. 1995 Nov 3;83(3):473-82.


Covalent and noncovalent DNA binding by mutants of vaccinia DNA topoisomerase I.

Morham SG, Shuman S.

J Biol Chem. 1992 Aug 5;267(22):15984-92.


Mapping the active-site tyrosine of vaccinia virus DNA topoisomerase I.

Shuman S, Kane EM, Morham SG.

Proc Natl Acad Sci U S A. 1989 Dec;86(24):9793-7.

Supplemental Content

Loading ...
Support Center