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Items: 1 to 50 of 106

1.

Using Flow Cytometry to Detect and Measure Intracellular Thiol Redox Status in Viable T Cells from Heterogeneous Populations.

Wadley AJ, Morgan RG, Darley RL, Hole PS, Coles SJ.

Methods Mol Biol. 2019;1990:53-70. doi: 10.1007/978-1-4939-9463-2_5.

PMID:
31148062
2.

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells.

Morgan RG, Ridsdale J, Payne M, Heesom KJ, Wilson MC, Davidson A, Greenhough A, Davies S, Williams AC, Blair A, Waterman ML, Tonks A, Darley RL.

Haematologica. 2019 Jul;104(7):1365-1377. doi: 10.3324/haematol.2018.202846. Epub 2019 Jan 10.

3.

Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers.

Wadley AJ, Morgan RG, Heesom KJ, Hole PS, Coles SJ.

MethodsX. 2018 Nov 1;5:1473-1483. doi: 10.1016/j.mex.2018.10.013. eCollection 2018.

4.

Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress.

Morgan RG, Walker AE, Trott DW, Machin DR, Henson GD, Reihl KD, Cawthon RM, Denchi EL, Liu Y, Bloom SI, Phuong TT, Richardson RS, Lesniewski LA, Donato AJ.

J Mol Cell Cardiol. 2019 Feb;127:74-82. doi: 10.1016/j.yjmcc.2018.11.014. Epub 2018 Nov 29.

PMID:
30502348
5.

Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic?

Morgan RG, Mortensson E, Williams AC.

Br J Cancer. 2018 May;118(11):1410-1418. doi: 10.1038/s41416-018-0118-6. Epub 2018 May 30. Review.

6.

Optimized delivery of siRNA into 3D tumor spheroid cultures in situ.

Morgan RG, Chambers AC, Legge DN, Coles SJ, Greenhough A, Williams AC.

Sci Rep. 2018 May 21;8(1):7952. doi: 10.1038/s41598-018-26253-3.

7.

Preliminary evidence of reductive stress in human cytotoxic T cells following exercise.

Wadley AJ, Holliday A, Morgan RG, Heesom KJ, Aldred S, Peters DM, Bueno AA, Coles SJ.

J Appl Physiol (1985). 2018 Aug 1;125(2):586-595. doi: 10.1152/japplphysiol.01137.2017. Epub 2018 Apr 12.

PMID:
29648517
8.

Telomere uncapping and vascular aging.

Morgan RG, Donato AJ, Walker AE.

Am J Physiol Heart Circ Physiol. 2018 Jul 1;315(1):H1-H5. doi: 10.1152/ajpheart.00008.2018. Epub 2018 Mar 16. Review.

9.

LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity.

Morgan RG, Mortensson E, Legge DN, Gupta B, Collard TJ, Greenhough A, Williams AC.

Br J Cancer. 2018 Feb 20;118(4):558-565. doi: 10.1038/bjc.2017.412. Epub 2017 Nov 16.

10.

Network Mendelian Randomization Study Design to Assess Factors Mediating the Causal Link Between Telomere Length and Heart Disease.

Morgan RG.

Circ Res. 2017 Jul 21;121(3):200-202. doi: 10.1161/CIRCRESAHA.117.311387. No abstract available.

PMID:
28729448
11.

Age-Associated ALU Element Instability in White Blood Cells Is Linked to Lower Survival in Elderly Adults: A Preliminary Cohort Study.

Morgan RG, Venturelli M, Gross C, Tarperi C, Schena F, Reggiani C, Naro F, Pedrinolla A, Monaco L, Richardson RS, Donato AJ.

PLoS One. 2017 Jan 6;12(1):e0169628. doi: 10.1371/journal.pone.0169628. eCollection 2017.

12.

Experimental reduction of miR-92a mimics arterial aging.

Hazra S, Henson GD, Morgan RG, Breevoort SR, Ives SJ, Richardson RS, Donato AJ, Lesniewski LA.

Exp Gerontol. 2016 Oct;83:165-70. doi: 10.1016/j.exger.2016.08.007. Epub 2016 Aug 11.

13.

Characterization of cognitive impairments and neurotransmitter changes in a novel transgenic mouse lacking Slc10a4.

Melief EJ, Gibbs JT, Li X, Morgan RG, Keene CD, Montine TJ, Palmiter RD, Darvas M.

Neuroscience. 2016 Jun 2;324:399-406. doi: 10.1016/j.neuroscience.2016.03.037. Epub 2016 Mar 19.

14.

Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.

Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparri M, Rokkas CK, Santos JH, Priel E, Gutterman DD.

Circ Res. 2016 Mar 4;118(5):856-66. doi: 10.1161/CIRCRESAHA.115.307918. Epub 2015 Dec 23.

15.

Age-related arterial telomere uncapping and senescence is greater in women compared with men.

Walker AE, Morgan RG, Ives SJ, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ.

Exp Gerontol. 2016 Jan;73:65-71. doi: 10.1016/j.exger.2015.11.009. Epub 2015 Nov 19.

16.

Relative contributions of severe dopaminergic neuron ablation and dopamine depletion to cognitive impairment.

Morgan RG, Gibbs JT, Melief EJ, Postupna NO, Sherfield EE, Wilson A, Keene CD, Montine TJ, Palmiter RD, Darvas M.

Exp Neurol. 2015 Sep;271:205-14. doi: 10.1016/j.expneurol.2015.06.013. Epub 2015 Jun 14.

17.

Cellular and molecular biology of aging endothelial cells.

Donato AJ, Morgan RG, Walker AE, Lesniewski LA.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):122-35. doi: 10.1016/j.yjmcc.2015.01.021. Epub 2015 Feb 2. Review.

18.

Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness.

Walker AE, Henson GD, Reihl KD, Morgan RG, Dobson PS, Nielson EI, Ling J, Mecham RP, Li DY, Lesniewski LA, Donato AJ.

J Physiol. 2015 Apr 15;593(8):1931-43. doi: 10.1113/jphysiol.2014.285338. Epub 2015 Feb 20.

19.

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.

Morgan RG, Molnár E, Jones RF, Collard TJ, Lane JD, Greenhough A, Paraskeva C, Williams AC.

Br J Cancer. 2015 Feb 17;112(4):714-9. doi: 10.1038/bjc.2015.4. Epub 2015 Jan 22.

20.

The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction.

Donato AJ, Henson GD, Hart CR, Layec G, Trinity JD, Bramwell RC, Enz RA, Morgan RG, Reihl KD, Hazra S, Walker AE, Richardson RS, Lesniewski LA.

J Physiol. 2014 Sep 15;592(18):4083-96. doi: 10.1113/jphysiol.2014.274175. Epub 2014 Jul 18.

21.

Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping.

Morgan RG, Ives SJ, Walker AE, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ.

J Hypertens. 2014 Jun;32(6):1293-9. doi: 10.1097/HJH.0000000000000157.

22.

Factors affecting the nuclear localization of β-catenin in normal and malignant tissue.

Morgan RG, Ridsdale J, Tonks A, Darley RL.

J Cell Biochem. 2014 Aug;115(8):1351-61. doi: 10.1002/jcb.24803. Review.

PMID:
24610469
23.

The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts.

Zabkiewicz J, Pearn L, Hills RK, Morgan RG, Tonks A, Burnett AK, Darley RL.

Haematologica. 2014 May;99(5):858-64. doi: 10.3324/haematol.2013.096487. Epub 2013 Dec 13.

24.

Beneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteries.

Walker AE, Henson GD, Reihl KD, Nielson EI, Morgan RG, Lesniewski LA, Donato AJ.

Age (Dordr). 2014 Apr;36(2):559-69. doi: 10.1007/s11357-013-9585-0. Epub 2013 Sep 25.

25.

Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries.

Morgan RG, Ives SJ, Lesniewski LA, Cawthon RM, Andtbacka RH, Noyes RD, Richardson RS, Donato AJ.

Am J Physiol Heart Circ Physiol. 2013 Jul 15;305(2):H251-8. doi: 10.1152/ajpheart.00197.2013. Epub 2013 May 10.

26.

γ-Catenin is expressed throughout normal human hematopoietic development and is required for normal PU.1-dependent monocyte differentiation.

Morgan RG, Liddiard K, Pearn L, Pumford SL, Burnett AK, Darley RL, Tonks A.

Leukemia. 2013 Oct;27(10):2096-100. doi: 10.1038/leu.2013.96. Epub 2013 Apr 2. No abstract available.

PMID:
23545990
27.

γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin.

Morgan RG, Pearn L, Liddiard K, Pumford SL, Burnett AK, Tonks A, Darley RL.

Leukemia. 2013 Feb;27(2):336-43. doi: 10.1038/leu.2012.221. Epub 2012 Aug 3.

28.

TNF-α impairs endothelial function in adipose tissue resistance arteries of mice with diet-induced obesity.

Donato AJ, Henson GD, Morgan RG, Enz RA, Walker AE, Lesniewski LA.

Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H672-9. doi: 10.1152/ajpheart.00271.2012. Epub 2012 Jul 20.

29.

α1-Adrenergic responsiveness in human skeletal muscle feed arteries: the impact of reducing extracellular pH.

Ives SJ, Andtbacka RH, Noyes RD, Morgan RG, Gifford JR, Park SY, Symons JD, Richardson RS.

Exp Physiol. 2013 Jan;98(1):256-67. doi: 10.1113/expphysiol.2012.066613. Epub 2012 Jul 13.

30.

HOX genes in ovarian cancer.

Kelly ZL, Michael A, Butler-Manuel S, Pandha HS, Morgan RG.

J Ovarian Res. 2011 Sep 9;4:16. doi: 10.1186/1757-2215-4-16.

31.

The effect of abdominoplasty on urinary incontinence in women.

Solanki NS, Duffield JA, Dean NR, Morgan RG.

Plast Reconstr Surg. 2010 Oct;126(4):206e-209e. doi: 10.1097/PRS.0b013e3181ea9372. No abstract available.

PMID:
20885227
32.

Human aging and CD31+ T-cell number, migration, apoptotic susceptibility, and telomere length.

Kushner EJ, Weil BR, MacEneaney OJ, Morgan RG, Mestek ML, Van Guilder GP, Diehl KJ, Stauffer BL, DeSouza CA.

J Appl Physiol (1985). 2010 Dec;109(6):1756-61. doi: 10.1152/japplphysiol.00601.2010. Epub 2010 Sep 23.

33.

CD31+ T cells represent a functionally distinct vascular T cell phenotype.

Kushner EJ, MacEneaney OJ, Morgan RG, Van Engelenburg AM, Van Guilder GP, DeSouza CA.

Blood Cells Mol Dis. 2010 Mar-Apr;44(2):74-8. doi: 10.1016/j.bcmd.2009.10.009. Epub 2009 Nov 7.

PMID:
19897387
34.

Asset retirement obligations: a reporting concern for healthcare facilities.

Berg GG, Bayes PE, Morgan RG.

Healthc Financ Manage. 2008 Nov;62(11):110-2, 114, 116.

PMID:
18990844
35.

New calibration technique for multiple-component stress wave force balances.

Abdel-jawad MM, Mee DJ, Morgan RG.

Rev Sci Instrum. 2007 Jun;78(6):065101.

PMID:
17614632
37.

Percutaneous radiologic drainage of pancreatic abscesses.

vanSonnenberg E, Wittich GR, Chon KS, D'Agostino HB, Casola G, Easter D, Morgan RG, Walser EM, Nealon WH, Goodacre B, Stabile BE.

AJR Am J Roentgenol. 1997 Apr;168(4):979-84.

PMID:
9124154
38.

New advances in electronic devices for hole detection.

Cox MJ, Bromberg WJ, Zura RD, Foresman PA, Morgan RG, Edlich RF.

J Appl Biomater. 1994;5(3):257-64.

PMID:
10147452
39.

Treatment of lymphedema of the arms and legs with 5,6-benzo-[alpha]-pyrone.

Casley-Smith JR, Morgan RG, Piller NB.

N Engl J Med. 1993 Oct 14;329(16):1158-63.

40.

The effect of trypsin inhibitor on the pancreas and small intestine of mice.

Ge YC, Morgan RG.

Br J Nutr. 1993 Jul;70(1):333-45.

PMID:
8399113
41.

Azaserine-induced pancreatic foci: detection, growth, labelling index and response to raw soya flour.

Daly JM, Morgan RG, Oates PS, Yeoh GC, Tee LB.

Carcinogenesis. 1992 Sep;13(9):1519-23.

PMID:
1394834
42.

Complex physical therapy for the lymphoedematous arm.

Morgan RG, Casley-Smith JR, Mason MR, Casley-Smith JR.

J Hand Surg Br. 1992 Aug;17(4):437-41.

PMID:
1402274
43.

A disposable emergency wound treatment kit.

Edlich RF, Jones KC Jr, Buchanan L, Morgan RG, McGregor W, Himel HN.

J Emerg Med. 1992 Jul-Aug;10(4):463-7. Review.

PMID:
1430984
44.
45.

Glutathione S-transferase (mu class) as an early marker of azaserine-induced foci in the rat pancreas.

Daly JM, Tee LB, Oates PS, Morgan RG, Yeoh GC.

Carcinogenesis. 1991 Jul;12(7):1237-40.

PMID:
1712677
46.
47.

Potentiation of azaserine by cholestyramine in the rat.

Morgan RG, Papadimitriou JM, Crass RA.

Int J Exp Pathol. 1990 Aug;71(4):485-91.

48.
49.

Physical therapy for lymphoedema.

Casley-Smith JR, Casley-Smith JR, Morgan RG.

Med J Aust. 1989 May 1;150(9):542-3. No abstract available.

PMID:
2725414
50.

Leucovorin enhancement of the effects of the fluoropyrimidines on thymidylate synthase.

Morgan RG.

Cancer. 1989 Mar 15;63(6 Suppl):1008-12. Review.

PMID:
2521810

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