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Items: 1 to 50 of 313

1.

Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma.

Raje N, Berdeja J, Lin Y, Siegel D, Jagannath S, Madduri D, Liedtke M, Rosenblatt J, Maus MV, Turka A, Lam LP, Morgan RA, Friedman K, Massaro M, Wang J, Russotti G, Yang Z, Campbell T, Hege K, Petrocca F, Quigley MT, Munshi N, Kochenderfer JN.

N Engl J Med. 2019 May 2;380(18):1726-1737. doi: 10.1056/NEJMoa1817226.

PMID:
31042825
2.

Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization.

Leung WH, Gay J, Martin U, Garrett TE, Horton HM, Certo MT, Blazar BR, Morgan RA, Gregory PD, Jarjour J, Astrakhan A.

JCI Insight. 2019 Apr 30;5. pii: 124430. doi: 10.1172/jci.insight.124430.

3.

Pilot Trial of Adoptive Transfer of Chimeric Antigen Receptor-transduced T Cells Targeting EGFRvIII in Patients With Glioblastoma.

Goff SL, Morgan RA, Yang JC, Sherry RM, Robbins PF, Restifo NP, Feldman SA, Lu YC, Lu L, Zheng Z, Xi L, Epstein M, McIntyre LS, Malekzadeh P, Raffeld M, Fine HA, Rosenberg SA.

J Immunother. 2019 May;42(4):126-135. doi: 10.1097/CJI.0000000000000260.

PMID:
30882547
4.

Adipose tissue dysfunction in obese horses with equine metabolic syndrome.

Reynolds A, Keen JA, Fordham T, Morgan RA.

Equine Vet J. 2019 Mar 13. doi: 10.1111/evj.13097. [Epub ahead of print]

PMID:
30866087
5.

The Role of Interventional Radiologists in Acute Ischemic Stroke Interventions: A Joint Position Statement from the Society of Interventional Radiology, the Cardiovascular and Interventional Radiology Society of Europe, and the Interventional Radiology Society of Australasia.

Sacks D, van Overhagen H, van Zwam WH, Radvany MG, Marx MV, Morgan RA, Vrazas JI, Goh GS.

J Vasc Interv Radiol. 2019 Feb;30(2):131-133. doi: 10.1016/j.jvir.2018.09.035. Epub 2018 Oct 29. No abstract available.

PMID:
30385239
6.

Dysregulation of Cortisol Metabolism in Equine Pituitary Pars Intermedia Dysfunction.

Morgan RA, Keen JA, Homer N, Nixon M, McKinnon-Garvin AM, Moses-Williams JA, Davis SR, Hadoke PWF, Walker BR.

Endocrinology. 2018 Nov 1;159(11):3791-3800. doi: 10.1210/en.2018-00726.

7.

A Review of the Current Status of Percutaneous Endovascular Arteriovenous Fistula Creation for Haemodialysis Access.

Jones RG, Morgan RA.

Cardiovasc Intervent Radiol. 2019 Jan;42(1):1-9. doi: 10.1007/s00270-018-2037-6. Epub 2018 Jul 20. Review.

PMID:
30030582
8.

Effective Targeting of Multiple B-Cell Maturation Antigen-Expressing Hematological Malignances by Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells.

Friedman KM, Garrett TE, Evans JW, Horton HM, Latimer HJ, Seidel SL, Horvath CJ, Morgan RA.

Hum Gene Ther. 2018 May;29(5):585-601. doi: 10.1089/hum.2018.001.

9.

Restricted MHC class I A locus diversity in olive and hybrid olive/yellow baboons from the Southwest National Primate Research Center.

Morgan RA, Karl JA, Bussan HE, Heimbruch KE, O'Connor DH, Dudley DM.

Immunogenetics. 2018 Jul;70(7):449-458. doi: 10.1007/s00251-018-1057-3. Epub 2018 Mar 28.

PMID:
29594415
10.

Complications and Reinterventions After Fenestrated and Branched EVAR in Patients with Paravisceral and Thoracoabdominal Aneurysms.

Huang IKH, Renani SA, Morgan RA.

Cardiovasc Intervent Radiol. 2018 Jul;41(7):985-997. doi: 10.1007/s00270-018-1917-0. Epub 2018 Mar 6. Review.

PMID:
29511866
11.

Embolization of a Mesenteric Arteriovenous Fistula.

Huang IKH, Ameli-Renani S, Ratnam L, Morgan RA.

J Vasc Interv Radiol. 2018 Feb;29(2):218. doi: 10.1016/j.jvir.2017.05.023. No abstract available.

PMID:
29414194
12.

Hematopoietic Stem Cell Gene Therapy: Progress and Lessons Learned.

Morgan RA, Gray D, Lomova A, Kohn DB.

Cell Stem Cell. 2017 Nov 2;21(5):574-590. doi: 10.1016/j.stem.2017.10.010. Review.

13.

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.

Morgan RA, Beck KR, Nixon M, Homer NZM, Crawford AA, Melchers D, Houtman R, Meijer OC, Stomby A, Anderson AJ, Upreti R, Stimson RH, Olsson T, Michoel T, Cohain A, Ruusalepp A, Schadt EE, Björkegren JLM, Andrew R, Kenyon CJ, Hadoke PWF, Odermatt A, Keen JA, Walker BR.

Sci Rep. 2017 Sep 6;7(1):10633. doi: 10.1038/s41598-017-10410-1.

14.

Genetic Modification of T Cells.

Morgan RA, Boyerinas B.

Biomedicines. 2016 Apr 20;4(2). pii: E9. doi: 10.3390/biomedicines4020009. Review.

15.

Early and midterm outcomes after transcatheter embolization of type I endoleaks in 25 patients.

Ameli-Renani S, Pavlidis V, Morgan RA.

J Vasc Surg. 2017 Feb;65(2):346-355. doi: 10.1016/j.jvs.2016.06.101.

16.

Percutaneous interventions following endovascular aneurysm sac sealing: Endoleak embolization and limb-related adverse events.

Ameli-Renani S, Morgan RA.

Semin Vasc Surg. 2016 Sep;29(3):135-141. doi: 10.1053/j.semvascsurg.2016.11.005. Epub 2016 Nov 5. Review.

PMID:
27989319
17.

Hypermutation In Pancreatic Cancer.

Humphris JL, Patch AM, Nones K, Bailey PJ, Johns AL, McKay S, Chang DK, Miller DK, Pajic M, Kassahn KS, Quinn MC, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Stone A, Wilson PJ, Anderson M, Fink JL, Holmes O, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Mead RS, Xu Q, Wu J, Pinese M, Cowley MJ, Jones MD, Nagrial AM, Chin VT, Chantrill LA, Mawson A, Chou A, Scarlett CJ, Pinho AV, Rooman I, Giry-Laterriere M, Samra JS, Kench JG, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Jamieson NB, McKay CJ, Carter CR, Dickson EJ, Graham JS, Duthie F, Oien K, Hair J, Morton JP, Sansom OJ, Grützmann R, Hruban RH, Maitra A, Iacobuzio-Donahue CA, Schulick RD, Wolfgang CL, Morgan RA, Lawlor RT, Rusev B, Corbo V, Salvia R, Cataldo I, Tortora G, Tempero MA; Australian Pancreatic Cancer Genome Initiative, Hofmann O, Eshleman JR, Pilarsky C, Scarpa A, Musgrove EA, Gill AJ, Pearson JV, Grimmond SM, Waddell N, Biankin AV.

Gastroenterology. 2017 Jan;152(1):68-74.e2. doi: 10.1053/j.gastro.2016.09.060. Epub 2016 Nov 15.

PMID:
27856273
18.

Secondary interventions after endovascular aneurysm sac sealing: endoleak embolization and limb-related interventions.

Ameli-Renani S, Morgan RA.

Semin Vasc Surg. 2016 Mar;29(1-2):61-67. doi: 10.1053/j.semvascsurg.2016.07.001. Epub 2016 Jul 12. Review.

PMID:
27823592
19.

Vascular Dysfunction in Horses with Endocrinopathic Laminitis.

Morgan RA, Keen JA, Walker BR, Hadoke PW.

PLoS One. 2016 Sep 29;11(9):e0163815. doi: 10.1371/journal.pone.0163815. eCollection 2016.

20.

ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.

Nixon M, Mackenzie SD, Taylor AI, Homer NZ, Livingstone DE, Mouras R, Morgan RA, Mole DJ, Stimson RH, Reynolds RM, Elfick AP, Andrew R, Walker BR.

Sci Transl Med. 2016 Aug 17;8(352):352ra109. doi: 10.1126/scitranslmed.aaf9074.

PMID:
27535620
21.

The Role of Adjustable Scout Lines in Advanced Cervical Spinal Imaging.

Hill BW, Song B, Morgan RA, Kang MM.

Clin Spine Surg. 2016 May 11. [Epub ahead of print]

PMID:
27171664
22.

Genomic analyses identify molecular subtypes of pancreatic cancer.

Bailey P, Chang DK, Nones K, Johns AL, Patch AM, Gingras MC, Miller DK, Christ AN, Bruxner TJ, Quinn MC, Nourse C, Murtaugh LC, Harliwong I, Idrisoglu S, Manning S, Nourbakhsh E, Wani S, Fink L, Holmes O, Chin V, Anderson MJ, Kazakoff S, Leonard C, Newell F, Waddell N, Wood S, Xu Q, Wilson PJ, Cloonan N, Kassahn KS, Taylor D, Quek K, Robertson A, Pantano L, Mincarelli L, Sanchez LN, Evers L, Wu J, Pinese M, Cowley MJ, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chantrill LA, Mawson A, Humphris J, Chou A, Pajic M, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Lovell JA, Merrett ND, Toon CW, Epari K, Nguyen NQ, Barbour A, Zeps N, Moran-Jones K, Jamieson NB, Graham JS, Duthie F, Oien K, Hair J, Grützmann R, Maitra A, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Rusev B, Capelli P, Salvia R, Tortora G, Mukhopadhyay D, Petersen GM; Australian Pancreatic Cancer Genome Initiative, Munzy DM, Fisher WE, Karim SA, Eshleman JR, Hruban RH, Pilarsky C, Morton JP, Sansom OJ, Scarpa A, Musgrove EA, Bailey UM, Hofmann O, Sutherland RL, Wheeler DA, Gill AJ, Gibbs RA, Pearson JV, Waddell N, Biankin AV, Grimmond SM.

Nature. 2016 Mar 3;531(7592):47-52. doi: 10.1038/nature16965. Epub 2016 Feb 24.

PMID:
26909576
23.

Salient Features of Endonuclease Platforms for Therapeutic Genome Editing.

Certo MT, Morgan RA.

Mol Ther. 2016 Mar;24(3):422-9. doi: 10.1038/mt.2016.21. Epub 2016 Jan 22. Review.

24.

Perioperative trends in plasma colloid osmotic pressure in horses undergoing surgery.

Raftery AG, Morgan RA, MacFarlane PD.

J Vet Emerg Crit Care (San Antonio). 2016 Jan-Feb;26(1):93-100. doi: 10.1111/vec.12369. Epub 2015 Sep 23.

PMID:
26397385
25.

Transiliac Paraendograft Embolisation of Type 2 Endoleak: An Alternative Approach for Endoleak Management.

Ameli-Renani S, Pavlidis V, Mailli L, Turner P, Morgan RA.

Cardiovasc Intervent Radiol. 2016 Feb;39(2):279-83. doi: 10.1007/s00270-015-1203-3. Epub 2015 Sep 21.

PMID:
26390874
26.

Transcatheter Embolisation of Proximal Type 1 Endoleaks Following Endovascular Aneurysm Sealing (EVAS) Using the Nellix Device: Technique and Outcomes.

Ameli-Renani S, Morgan RA.

Cardiovasc Intervent Radiol. 2015 Oct;38(5):1137-42. doi: 10.1007/s00270-015-1171-7. Epub 2015 Jul 10.

PMID:
26159356
27.

Appearance of the Nellix endovascular aneurysm sealing system on computed tomography: implications for postoperative imaging surveillance.

Karthikesalingam A, de Bruin JL, Patel SR, Azhar B, Rossi L, Morgan RA, Holt PJ, Loftus IM, Thompson MM.

J Endovasc Ther. 2015 Jun;22(3):297-302. doi: 10.1177/1526602815583455.

PMID:
25991765
28.

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.

Beane JD, Lee G, Zheng Z, Mendel M, Abate-Daga D, Bharathan M, Black M, Gandhi N, Yu Z, Chandran S, Giedlin M, Ando D, Miller J, Paschon D, Guschin D, Rebar EJ, Reik A, Holmes MC, Gregory PD, Restifo NP, Rosenberg SA, Morgan RA, Feldman SA.

Mol Ther. 2015 Aug;23(8):1380-1390. doi: 10.1038/mt.2015.71. Epub 2015 May 5.

29.

Endovascular aneurysm sealing for the treatment of ruptured abdominal aortic aneurysms.

de Bruin JL, Brownrigg JR, Karthikesalingam A, Patterson BO, Holt PJ, Hinchliffe RJ, Morgan RA, Loftus IM, Thompson MM.

J Endovasc Ther. 2015 Jun;22(3):283-7. doi: 10.1177/1526602815582529. Epub 2015 Apr 22.

30.

Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity.

Liu L, Patel B, Ghanem MH, Bundoc V, Zheng Z, Morgan RA, Rosenberg SA, Dey B, Berger EA.

J Virol. 2015 Jul;89(13):6685-94. doi: 10.1128/JVI.00474-15. Epub 2015 Apr 15.

31.

Osteoporosis in acute fractures of the cervical spine: the role of opportunistic CT screening.

Emohare O, Dittmer A, Morgan RA, Switzer JA, Polly DW Jr.

J Neurosurg Spine. 2015 Jul;23(1):1-7. doi: 10.3171/2014.10.SPINE14233. Epub 2015 Apr 10.

PMID:
25860516
32.

Sonographic appearance following endovascular aneurysm repair using the Nellix endovascular sealing system.

D'Abate F, Harrison SA, Karthikesalingam A, de Bruin J, Hinchliffe RJ, Loftus IM, Holt PJ, Morgan RA, Thompson MM.

J Endovasc Ther. 2015 Apr;22(2):182-6. doi: 10.1177/1526602815576098. No abstract available.

PMID:
25809358
33.

Treatment of equine metabolic syndrome: A clinical case series.

Morgan RA, Keen JA, McGowan CM.

Equine Vet J. 2016 Jul;48(4):422-6. doi: 10.1111/evj.12445. Epub 2015 Jun 18.

PMID:
25808563
34.

Thoracic Endovascular Aortic Repair for the Treatment of Aortic Dissection: Post-operative Imaging, Complications and Secondary Interventions.

Ameli-Renani S, Das R, Morgan RA.

Cardiovasc Intervent Radiol. 2015 Dec;38(6):1391-404. doi: 10.1007/s00270-015-1072-9. Epub 2015 Mar 24. Review.

PMID:
25799947
35.

Whole genomes redefine the mutational landscape of pancreatic cancer.

Waddell N, Pajic M, Patch AM, Chang DK, Kassahn KS, Bailey P, Johns AL, Miller D, Nones K, Quek K, Quinn MC, Robertson AJ, Fadlullah MZ, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Wani S, Wilson PJ, Markham E, Cloonan N, Anderson MJ, Fink JL, Holmes O, Kazakoff SH, Leonard C, Newell F, Poudel B, Song S, Taylor D, Waddell N, Wood S, Xu Q, Wu J, Pinese M, Cowley MJ, Lee HC, Jones MD, Nagrial AM, Humphris J, Chantrill LA, Chin V, Steinmann AM, Mawson A, Humphrey ES, Colvin EK, Chou A, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Pettitt JA, Merrett ND, Toon C, Epari K, Nguyen NQ, Barbour A, Zeps N, Jamieson NB, Graham JS, Niclou SP, Bjerkvig R, Grützmann R, Aust D, Hruban RH, Maitra A, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Falconi M, Zamboni G, Tortora G, Tempero MA; Australian Pancreatic Cancer Genome Initiative, Gill AJ, Eshleman JR, Pilarsky C, Scarpa A, Musgrove EA, Pearson JV, Biankin AV, Grimmond SM.

Nature. 2015 Feb 26;518(7540):495-501. doi: 10.1038/nature14169.

36.

Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma.

Zhang L, Morgan RA, Beane JD, Zheng Z, Dudley ME, Kassim SH, Nahvi AV, Ngo LT, Sherry RM, Phan GQ, Hughes MS, Kammula US, Feldman SA, Toomey MA, Kerkar SP, Restifo NP, Yang JC, Rosenberg SA.

Clin Cancer Res. 2015 May 15;21(10):2278-88. doi: 10.1158/1078-0432.CCR-14-2085. Epub 2015 Feb 18.

37.

Embolisation of a proximal type I endoleak post-Nellix aortic aneurysm repair complicated by reflux of Onyx into the Nellix endograft limb.

Ameli-Renani S, Das R, Weller A, Chung R, Morgan RA.

Cardiovasc Intervent Radiol. 2015 Jun;38(3):747-51. doi: 10.1007/s00270-014-1044-5. Epub 2014 Dec 30.

PMID:
25547081
38.

A pilot trial using lymphocytes genetically engineered with an NY-ESO-1-reactive T-cell receptor: long-term follow-up and correlates with response.

Robbins PF, Kassim SH, Tran TL, Crystal JS, Morgan RA, Feldman SA, Yang JC, Dudley ME, Wunderlich JR, Sherry RM, Kammula US, Hughes MS, Restifo NP, Raffeld M, Lee CC, Li YF, El-Gamil M, Rosenberg SA.

Clin Cancer Res. 2015 Mar 1;21(5):1019-27. doi: 10.1158/1078-0432.CCR-14-2708. Epub 2014 Dec 23.

39.

Multiple chimeric antigen receptors successfully target chondroitin sulfate proteoglycan 4 in several different cancer histologies and cancer stem cells.

Beard RE, Zheng Z, Lagisetty KH, Burns WR, Tran E, Hewitt SM, Abate-Daga D, Rosati SF, Fine HA, Ferrone S, Rosenberg SA, Morgan RA.

J Immunother Cancer. 2014 Aug 19;2:25. doi: 10.1186/2051-1426-2-25. eCollection 2014.

40.

Type 2 Endoleaks Post-EVAR: Current Evidence for Rupture Risk, Intervention and Outcomes of Treatment.

Chung R, Morgan RA.

Cardiovasc Intervent Radiol. 2015 Jun;38(3):507-22. doi: 10.1007/s00270-014-0987-x. Epub 2014 Sep 5. Review.

PMID:
25189665
41.

Pancreatic cancer: Hurdles in the engineering of CAR-based immunotherapies.

Abate-Daga D, Rosenberg SA, Morgan RA.

Oncoimmunology. 2014 Jun 18;3:e29194. eCollection 2014.

42.

Use of the piggyBac transposon to create stable packaging cell lines for the production of clinical-grade self-inactivating γ-retroviral vectors.

Feldman SA, Xu H, Black MA, Park TS, Robbins PF, Kochenderfer JN, Morgan RA, Rosenberg SA.

Hum Gene Ther Methods. 2014 Aug;25(4):253-60. doi: 10.1089/hgtb.2014.071.

43.

Gamma-retroviral vector design for the co-expression of artificial microRNAs and therapeutic proteins.

Park TS, Abate-Daga D, Zhang L, Zheng Z, Morgan RA.

Nucleic Acid Ther. 2014 Oct;24(5):356-63. doi: 10.1089/nat.2014.0486. Epub 2014 Jul 14.

44.

Boolean immunotherapy: reversal of fortune.

Morgan RA.

Mol Ther. 2014 Jun;22(6):1073-1074. doi: 10.1038/mt.2014.75. No abstract available.

45.

A novel chimeric antigen receptor against prostate stem cell antigen mediates tumor destruction in a humanized mouse model of pancreatic cancer.

Abate-Daga D, Lagisetty KH, Tran E, Zheng Z, Gattinoni L, Yu Z, Burns WR, Miermont AM, Teper Y, Rudloff U, Restifo NP, Feldman SA, Rosenberg SA, Morgan RA.

Hum Gene Ther. 2014 Dec;25(12):1003-12. doi: 10.1089/hum.2013.209.

46.

Development of a T cell receptor targeting an HLA-A*0201 restricted epitope from the cancer-testis antigen SSX2 for adoptive immunotherapy of cancer.

Abate-Daga D, Speiser DE, Chinnasamy N, Zheng Z, Xu H, Feldman SA, Rosenberg SA, Morgan RA.

PLoS One. 2014 Mar 28;9(3):e93321. doi: 10.1371/journal.pone.0093321. eCollection 2014.

47.

Impact of water-soaking on the nutrient composition of UK hays.

Mack SJ, Dugdale AH, Argo CM, Morgan RA, McGowan CM.

Vet Rec. 2014 May 3;174(18):452. doi: 10.1136/vr.102074. Epub 2014 Mar 27. No abstract available.

PMID:
24675773
48.

Prevalence and risk factors for hyperinsulinaemia in ponies in Queensland, Australia.

Morgan RA, McGowan TW, McGowan CM.

Aust Vet J. 2014 Apr;92(4):101-6. doi: 10.1111/avj.12159.

PMID:
24673135
49.

Genetic modification of T cells.

Morgan RA, Kakarla S.

Cancer J. 2014 Mar-Apr;20(2):145-50. doi: 10.1097/PPO.0000000000000033. Review.

PMID:
24667961
50.

A novel murine T-cell receptor targeting NY-ESO-1.

Rosati SF, Parkhurst MR, Hong Y, Zheng Z, Feldman SA, Rao M, Abate-Daga D, Beard RE, Xu H, Black MA, Robbins PF, Schrump DA, Rosenberg SA, Morgan RA.

J Immunother. 2014 Apr;37(3):135-46. doi: 10.1097/CJI.0000000000000019.

PMID:
24598449

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