Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 92

1.

Relevance of experimental paradigms of anesthesia induced neurotoxicity in the mouse.

Johnson SC, Pan A, Sun GX, Freed A, Stokes JC, Bornstein R, Witkowski M, Li L, Ford JM, Howard CRA, Sedensky MM, Morgan PG.

PLoS One. 2019 Mar 21;14(3):e0213543. doi: 10.1371/journal.pone.0213543. eCollection 2019.

2.

A Summary of Preclinical Poster Presentations at the Sixth Biennial Pediatric Anesthesia Neurodevelopment Assessment (PANDA) Symposium.

Griffiths KK, Morgan PG, Johnson SC, Nambyiah P, Soriano SG, Johnson K, Xu J, Garber C, Maxwell L, Saraiya N.

J Neurosurg Anesthesiol. 2019 Jan;31(1):163-165. doi: 10.1097/ANA.0000000000000542.

PMID:
30767942
3.

Mitochondrial Function in Astrocytes Is Essential for Normal Emergence from Anesthesia in Mice.

Ramadasan-Nair R, Hui J, Itsara LS, Morgan PG, Sedensky MM.

Anesthesiology. 2019 Mar;130(3):423-434. doi: 10.1097/ALN.0000000000002528.

PMID:
30707122
4.

mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases.

Johnson SC, Martinez F, Bitto A, Gonzalez B, Tazaerslan C, Cohen C, Delaval L, Timsit J, Knebelmann B, Terzi F, Mahal T, Zhu Y, Morgan PG, Sedensky MM, Kaeberlein M, Legendre C, Suh Y, Canaud G.

Kidney Int. 2019 Feb;95(2):455-466. doi: 10.1016/j.kint.2018.08.038. Epub 2018 Nov 22.

PMID:
30471880
5.

Traumatic Brain Injury in Flies.

Morgan PG, Sedensky MM.

Anesth Analg. 2018 Nov;127(5):e90. doi: 10.1213/ANE.0000000000003753. No abstract available.

PMID:
30169414
6.

Anesthetics Have Different Effects on the Electrocorticographic Spectra of Wild-type and Mitochondrial Mutant Mice.

Carspecken CW, Chanprasert S, Kalume F, Sedensky MM, Morgan PG.

Anesthesiology. 2018 Oct;129(4):744-755. doi: 10.1097/ALN.0000000000002368.

PMID:
30074932
7.

Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I.

Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM.

Br J Anaesth. 2018 May;120(5):1019-1032. doi: 10.1016/j.bja.2018.01.036. Epub 2018 Mar 13.

8.

General Genetic Strategies.

Steele LM, Morgan PG.

Methods Enzymol. 2018;602:113-132. doi: 10.1016/bs.mie.2018.01.005. Epub 2018 Mar 9.

PMID:
29588025
9.

Regional knockdown of NDUFS4 implicates a thalamocortical circuit mediating anesthetic sensitivity.

Ramadasan-Nair R, Hui J, Zimin PI, Itsara LS, Morgan PG, Sedensky MM.

PLoS One. 2017 Nov 14;12(11):e0188087. doi: 10.1371/journal.pone.0188087. eCollection 2017.

10.

Cell Biology of the Mitochondrion.

van der Bliek AM, Sedensky MM, Morgan PG.

Genetics. 2017 Nov;207(3):843-871. doi: 10.1534/genetics.117.300262. Review. Erratum in: Genetics. 2018 Apr;208(4):1673.

11.

Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.

Bennett CF, Kwon JJ, Chen C, Russell J, Acosta K, Burnaevskiy N, Crane MM, Bitto A, Vander Wende H, Simko M, Pineda V, Rossner R, Wasko BM, Choi H, Chen S, Park S, Jafari G, Sands B, Perez Olsen C, Mendenhall AR, Morgan PG, Kaeberlein M.

PLoS Genet. 2017 Mar 29;13(3):e1006695. doi: 10.1371/journal.pgen.1006695. eCollection 2017 Mar.

12.

The genetics of isoflurane-induced developmental neurotoxicity.

Na HS, Brockway NL, Gentry KR, Opheim E, Sedensky MM, Morgan PG.

Neurotoxicol Teratol. 2017 Mar - Apr;60:40-49. doi: 10.1016/j.ntt.2016.10.012. Epub 2016 Oct 29.

13.

Glutamatergic Neurotransmission Links Sensitivity to Volatile Anesthetics with Mitochondrial Function.

Zimin PI, Woods CB, Quintana A, Ramirez JM, Morgan PG, Sedensky MM.

Curr Biol. 2016 Aug 22;26(16):2194-201. doi: 10.1016/j.cub.2016.06.020. Epub 2016 Aug 4.

14.

Ketamine and Mitochondrial Function.

Morgan PG, Sedensky MM, Kayser EB.

Anesth Analg. 2016 Mar;122(3):917-8. doi: 10.1213/ANE.0000000000000872. No abstract available.

PMID:
26891403
15.

Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain.

Kayser EB, Sedensky MM, Morgan PG.

PLoS One. 2016 Jan 29;11(1):e0148219. doi: 10.1371/journal.pone.0148219. eCollection 2016.

16.

Glutathione S-transferase mediates an ageing response to mitochondrial dysfunction.

Dancy BM, Brockway N, Ramadasan-Nair R, Yang Y, Sedensky MM, Morgan PG.

Mech Ageing Dev. 2016 Jan;153:14-21. doi: 10.1016/j.mad.2015.12.001. Epub 2015 Dec 15.

17.

Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron-sulfur protein.

Jafari G, Wasko BM, Tonge A, Schurman N, Dong C, Li Z, Peters R, Kayser EB, Pitt JN, Morgan PG, Sedensky MM, Crofts AR, Kaeberlein M.

Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6148-57. doi: 10.1073/pnas.1509416112. Epub 2015 Oct 26.

18.

Forward to the past.

Eckenhoff RG, Morgan PG.

Anesth Analg. 2015 Feb;120(2):259-60. doi: 10.1213/ANE.0000000000000534. No abstract available.

PMID:
25602447
19.

Mitochondrial bioenergetics and disease in Caenorhabditis elegans.

Dancy BM, Sedensky MM, Morgan PG.

Front Biosci (Landmark Ed). 2015 Jan 1;20:198-228. Review.

PMID:
25553447
20.

Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans.

Morgan PG, Higdon R, Kolker N, Bauman AT, Ilkayeva O, Newgard CB, Kolker E, Steele LM, Sedensky MM.

Mitochondrion. 2015 Jan;20:95-102. doi: 10.1016/j.mito.2014.12.004. Epub 2014 Dec 19.

21.

A Drosophila model of mitochondrial disease caused by a complex I mutation that uncouples proton pumping from electron transfer.

Burman JL, Itsara LS, Kayser EB, Suthammarak W, Wang AM, Kaeberlein M, Sedensky MM, Morgan PG, Pallanck LJ.

Dis Model Mech. 2014 Oct;7(10):1165-74. doi: 10.1242/dmm.015321. Epub 2014 Aug 1.

22.

Effects of the mitochondrial respiratory chain on longevity in C. elegans.

Dancy BM, Sedensky MM, Morgan PG.

Exp Gerontol. 2014 Aug;56:245-55. doi: 10.1016/j.exger.2014.03.028. Epub 2014 Apr 5. Review.

PMID:
24709342
23.

Propofol compared with isoflurane inhibits mitochondrial metabolism in immature swine cerebral cortex.

Kajimoto M, Atkinson DB, Ledee DR, Kayser EB, Morgan PG, Sedensky MM, Isern NG, Des Rosiers C, Portman MA.

J Cereb Blood Flow Metab. 2014 Mar;34(3):514-21. doi: 10.1038/jcbfm.2013.229. Epub 2014 Jan 8.

24.

mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome.

Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, Morgan PG, Sedensky MM, Kaeberlein M.

Science. 2013 Dec 20;342(6165):1524-8. doi: 10.1126/science.1244360. Epub 2013 Nov 14.

25.

The power of unbiased genetic screens to discover novel anesthetic targets.

Morgan PG, Sedensky MM.

Anesthesiology. 2013 Oct;119(4):995-6. doi: 10.1097/ALN.0b013e3182a4465c. No abstract available.

PMID:
24195887
26.

Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure.

Karamanlidis G, Lee CF, Garcia-Menendez L, Kolwicz SC Jr, Suthammarak W, Gong G, Sedensky MM, Morgan PG, Wang W, Tian R.

Cell Metab. 2013 Aug 6;18(2):239-50. doi: 10.1016/j.cmet.2013.07.002.

27.

Novel interactions between mitochondrial superoxide dismutases and the electron transport chain.

Suthammarak W, Somerlot BH, Opheim E, Sedensky M, Morgan PG.

Aging Cell. 2013 Dec;12(6):1132-40. doi: 10.1111/acel.12144. Epub 2013 Sep 11.

28.

Anesthetic considerations in patients with mitochondrial defects.

Niezgoda J, Morgan PG.

Paediatr Anaesth. 2013 Sep;23(9):785-93. doi: 10.1111/pan.12158. Epub 2013 Mar 28. Review.

29.

Early developmental exposure to volatile anesthetics causes behavioral defects in Caenorhabditis elegans.

Gentry KR, Steele LM, Sedensky MM, Morgan PG.

Anesth Analg. 2013 Jan;116(1):185-9. doi: 10.1213/ANE.0b013e31826d37c5. Epub 2012 Dec 7.

30.

Altered anesthetic sensitivity of mice lacking Ndufs4, a subunit of mitochondrial complex I.

Quintana A, Morgan PG, Kruse SE, Palmiter RD, Sedensky MM.

PLoS One. 2012;7(8):e42904. doi: 10.1371/journal.pone.0042904. Epub 2012 Aug 17.

31.

The worm sheds light on anesthetic mechanisms.

Singaram VK, Morgan PG, Sedensky MM.

Worm. 2012;1(3):164-169.

32.

Optical reversal of halothane-induced immobility in C. elegans.

Singaram VK, Somerlot BH, Falk SA, Falk MJ, Sedensky MM, Morgan PG.

Curr Biol. 2011 Dec 20;21(24):2070-6. doi: 10.1016/j.cub.2011.10.042. Epub 2011 Dec 1.

33.

Treatment of cocaine overdose with lipid emulsion.

Jakkala-Saibaba R, Morgan PG, Morton GL.

Anaesthesia. 2011 Dec;66(12):1168-70. doi: 10.1111/j.1365-2044.2011.06895.x.

34.

Important new model for studying anesthetic action.

Morgan PG.

Anesth Analg. 2011 Nov;113(5):982-3. doi: 10.1213/ANE.0b013e31822e9861. No abstract available.

PMID:
22021797
35.

Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport.

Pfeiffer M, Kayzer EB, Yang X, Abramson E, Kenaston MA, Lago CU, Lo HH, Sedensky MM, Lunceford A, Clarke CF, Wu SJ, McLeod C, Finkel T, Morgan PG, Mills EM.

J Biol Chem. 2011 Oct 28;286(43):37712-20. doi: 10.1074/jbc.M111.271452. Epub 2011 Aug 23.

36.

The role of DMQ(9) in the long-lived mutant clk-1.

Yang YY, Vasta V, Hahn S, Gangoiti JA, Opheim E, Sedensky MM, Morgan PG.

Mech Ageing Dev. 2011 Jun-Jul;132(6-7):331-9. doi: 10.1016/j.mad.2011.06.009. Epub 2011 Jul 1.

37.

Isoflurane selectively inhibits distal mitochondrial complex I in Caenorhabditis elegans.

Kayser EB, Suthammarak W, Morgan PG, Sedensky MM.

Anesth Analg. 2011 Jun;112(6):1321-9. doi: 10.1213/ANE.0b013e3182121d37. Epub 2011 Apr 5.

38.

A new phase in anesthetic-induced neurotoxicity research.

Morgan PG, Sedensky M.

Anesthesiology. 2011 Jan;114(1):10-1. doi: 10.1097/ALN.0b013e318201dda0. No abstract available.

PMID:
21150570
39.

Mutations in mitochondrial complex III uniquely affect complex I in Caenorhabditis elegans.

Suthammarak W, Morgan PG, Sedensky MM.

J Biol Chem. 2010 Dec 24;285(52):40724-31. doi: 10.1074/jbc.M110.159608. Epub 2010 Oct 22.

40.

Alternatives to mammalian pain models 1: use of C. elegans for the study of volatile anesthetics.

Steele LM, Sedensky MM, Morgan PG.

Methods Mol Biol. 2010;617:1-17. doi: 10.1007/978-1-60327-323-7_1.

PMID:
20336409
41.

Subcomplex Ilambda specifically controls integrated mitochondrial functions in Caenorhabditis elegans.

Falk MJ, Rosenjack JR, Polyak E, Suthammarak W, Chen Z, Morgan PG, Sedensky MM.

PLoS One. 2009 Aug 12;4(8):e6607. doi: 10.1371/journal.pone.0006607.

42.

The effect of different ubiquinones on lifespan in Caenorhabditis elegans.

Yang YY, Gangoiti JA, Sedensky MM, Morgan PG.

Mech Ageing Dev. 2009 Jun;130(6):370-6. doi: 10.1016/j.mad.2009.03.003. Epub 2009 Mar 25.

43.

Complex I function is defective in complex IV-deficient Caenorhabditis elegans.

Suthammarak W, Yang YY, Morgan PG, Sedensky MM.

J Biol Chem. 2009 Mar 6;284(10):6425-35. doi: 10.1074/jbc.M805733200. Epub 2008 Dec 12.

44.

Genetics and the evolution of the anesthetic response.

Sedensky MM, Morgan PG.

Anesth Analg. 2008 Sep;107(3):855-8. doi: 10.1213/ane.0b013e31817d864a. No abstract available.

PMID:
18713894
45.

Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

Falk MJ, Zhang Z, Rosenjack JR, Nissim I, Daikhin E, Nissim I, Sedensky MM, Yudkoff M, Morgan PG.

Mol Genet Metab. 2008 Apr;93(4):388-97. doi: 10.1016/j.ymgme.2007.11.007. Epub 2008 Feb 21.

46.

C. elegans and volatile anesthetics.

Morgan PG, Kayser EB, Sedensky MM.

WormBook. 2007 May 3:1-11. Review.

47.

Lack of renoprotective effect of i.v. N-acetylcysteine in patients with chronic renal failure.

Morgan PG, Georghiou M, Flynn F, Jaggar S.

Br J Anaesth. 2007 Jul;99(1):143; author reply 143-4. No abstract available.

48.

A putative cation channel and its novel regulator: cross-species conservation of effects on general anesthesia.

Humphrey JA, Hamming KS, Thacker CM, Scott RL, Sedensky MM, Snutch TP, Morgan PG, Nash HA.

Curr Biol. 2007 Apr 3;17(7):624-9. Epub 2007 Mar 15.

49.

Sulfated signal from ASJ sensory neurons modulates stomatin-dependent coordination in Caenorhabditis elegans.

Carroll BT, Dubyak GR, Sedensky MM, Morgan PG.

J Biol Chem. 2006 Nov 24;281(47):35989-96. Epub 2006 Sep 13.

Supplemental Content

Loading ...
Support Center