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Are the measurement properties of incremental exercise tests similar between patients with COPD and CHF?

Harvey-Dunstan TC, Singh SJ, Steiner MC, Morgan MD, Evans RA.

Chron Respir Dis. 2019 Jan-Dec;16:1479973119887965. doi: 10.1177/1479973119887965.


Author Correction: Challenges in measuring and understanding biological noise.

Eling N, Morgan MD, Marioni JC.

Nat Rev Genet. 2019 Sep;20(9):562. doi: 10.1038/s41576-019-0142-2.


Challenges in measuring and understanding biological noise.

Eling N, Morgan MD, Marioni JC.

Nat Rev Genet. 2019 Sep;20(9):536-548. doi: 10.1038/s41576-019-0130-6. Review. Erratum in: Nat Rev Genet. 2019 Jun 3;:.


24-hour accelerometry in COPD: Exploring physical activity, sedentary behavior, sleep and clinical characteristics.

Orme MW, Steiner MC, Morgan MD, Kingsnorth AP, Esliger DW, Singh SJ, Sherar LB.

Int J Chron Obstruct Pulmon Dis. 2019 Feb 18;14:419-430. doi: 10.2147/COPD.S183029. eCollection 2019.


Changes in physical activity during hospital admission for chronic respiratory disease.

Orme MW, Harvey-Dunstan TC, Boral I, Chaplin EJL, Hussain SF, Morgan MDL, Steiner MC, Singh SJ, Greening NJ.

Respirology. 2019 Jul;24(7):652-657. doi: 10.1111/resp.13513. Epub 2019 Mar 7.


Intravenous pulse methylprednisolone for induction of remission in severe ANCA associated Vasculitis: a multi-center retrospective cohort study.

Chanouzas D, McGregor JAG, Nightingale P, Salama AD, Szpirt WM, Basu N, Morgan MD, Poulton CJ, Draibe JB, Krarup E, Dospinescu P, Dale JA, Pendergraft WF, Lee K, Egfjord M, Hogan SL, Harper L.

BMC Nephrol. 2019 Feb 18;20(1):58. doi: 10.1186/s12882-019-1226-0.


Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.

Fergusson JR, Morgan MD, Bruchard M, Huitema L, Heesters BA, van Unen V, van Hamburg JP, van der Wel NN, Picavet D, Koning F, Tas SW, Anderson MS, Marioni JC, Holländer GA, Spits H.

Front Immunol. 2019 Jan 14;9:2902. doi: 10.3389/fimmu.2018.02902. eCollection 2018.


Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.

Morgan MD, Pairo-Castineira E, Rawlik K, Canela-Xandri O, Rees J, Sims D, Tenesa A, Jackson IJ.

Nat Commun. 2018 Dec 10;9(1):5271. doi: 10.1038/s41467-018-07691-z.


Treatment of fatigue with physical activity and behavioural change support in vasculitis: study protocol for an open-label randomised controlled feasibility study.

Harper L, Morgan MD, Chanouzas D, Caulfield HK, Coughlan L, Dean C, Fletcher K, Cramp F, Greenfield S, Hewitt CA, Ives NJ, Jowett S, Daley A.

BMJ Open. 2018 Oct 30;8(10):e023769. doi: 10.1136/bmjopen-2018-023769.


The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis.

Chanouzas D, Sagmeister M, Dyall L, Sharp P, Powley L, Johal S, Bowen J, Nightingale P, Ferro CJ, Morgan MD, Moss P, Harper L.

Arthritis Res Ther. 2018 Aug 29;20(1):194. doi: 10.1186/s13075-018-1695-8.


Subclinical Reactivation of Cytomegalovirus Drives CD4+CD28null T-Cell Expansion and Impaired Immune Response to Pneumococcal Vaccination in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Chanouzas D, Sagmeister M, Faustini S, Nightingale P, Richter A, Ferro CJ, Morgan MD, Moss P, Harper L.

J Infect Dis. 2019 Jan 7;219(2):234-244. doi: 10.1093/infdis/jiy493.


CpG island composition differences are a source of gene expression noise indicative of promoter responsiveness.

Morgan MD, Marioni JC.

Genome Biol. 2018 Jun 26;19(1):81. doi: 10.1186/s13059-018-1461-x.


Humoral immunity to memory antigens and pathogens is maintained in patients with chronic kidney disease.

Wall NA, Dominguez-Medina CC, Faustini SE, Cook CN, McClean A, Jesky MD, Perez-Toledo M, Morgan MD, Richter AG, Ferro CJ, Cockwell P, Moss PA, Henderson IR, Harper L, Cunningham AF.

PLoS One. 2018 Apr 16;13(4):e0195730. doi: 10.1371/journal.pone.0195730. eCollection 2018.


Findings of the Chronic Obstructive Pulmonary Disease-Sitting and Exacerbations Trial (COPD-SEAT) in Reducing Sedentary Time Using Wearable and Mobile Technologies With Educational Support: Randomized Controlled Feasibility Trial.

Orme MW, Weedon AE, Saukko PM, Esliger DW, Morgan MD, Steiner MC, Downey JW, Sherar LB, Singh SJ.

JMIR Mhealth Uhealth. 2018 Apr 11;6(4):e84. doi: 10.2196/mhealth.9398.


Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors.

Haghverdi L, Lun ATL, Morgan MD, Marioni JC.

Nat Biotechnol. 2018 Jun;36(5):421-427. doi: 10.1038/nbt.4091. Epub 2018 Apr 2.


Survival following pulmonary rehabilitation in patients with COPD: the effect of program completion and change in incremental shuttle walking test distance.

Houchen-Wolloff L, Williams JE, Green RH, Woltmann G, Steiner MC, Sewell L, Morgan MD, Singh SJ.

Int J Chron Obstruct Pulmon Dis. 2017 Dec 20;13:37-44. doi: 10.2147/COPD.S143101. eCollection 2018.


Chronic obstructive pulmonary disease (COPD), illness narratives and Elias's sociology of knowledge.

Malcolm D, Orme MW, Morgan MD, Sherar LB.

Soc Sci Med. 2017 Nov;192:58-65. doi: 10.1016/j.socscimed.2017.09.022. Epub 2017 Sep 18.


Experiences of patients undergoing pulmonary rehabilitation during an exacerbation of chronic respiratory disease.

Vincent EE, Chaplin EJ, Williams JE, Harvey-Dunstan T, Greening NJ, Steiner MC, Morgan MD, Singh SJ.

Chron Respir Dis. 2017 Aug;14(3):298-308. doi: 10.1177/1479972317695812. Epub 2017 Mar 9.


Negative anti-neutrophil cytoplasm antibody at switch to maintenance therapy is associated with a reduced risk of relapse.

Morgan MD, Szeto M, Walsh M, Jayne D, Westman K, Rasmussen N, Hiemstra TF, Flossmann O, Berden A, Höglund P, Harper L; European Vasculitis Society.

Arthritis Res Ther. 2017 Jun 7;19(1):129. doi: 10.1186/s13075-017-1321-1.


Individualised risk in patients undergoing lung volume reduction surgery: the Glenfield BFG score.

Greening NJ, Vaughan P, Oey I, Steiner MC, Morgan MD, Rathinam S, Waller DA.

Eur Respir J. 2017 Jun 1;49(6). pii: 1601766. doi: 10.1183/13993003.01766-2016. Print 2017 Jun.


Agreement between adherences to four physical activity recommendations in patients with COPD: does the incremental shuttle walk test predict adherence?

Mitchell KE, Johnson V, Houchen-Wolloff L, Sewell L, Morgan MD, Steiner MC, Singh SJ.

Clin Respir J. 2018 Feb;12(2):510-516. doi: 10.1111/crj.12555. Epub 2016 Oct 13.


Study protocol for Chronic Obstructive Pulmonary Disease-Sitting and ExacerbAtions Trial (COPD-SEAT): a randomised controlled feasibility trial of a home-based self-monitoring sedentary behaviour intervention.

Orme MW, Weedon AE, Esliger DW, Saukko PM, Morgan MD, Steiner MC, Downey JW, Singh SJ, Sherar LB.

BMJ Open. 2016 Oct 3;6(10):e013014. doi: 10.1136/bmjopen-2016-013014. Erratum in: BMJ Open. 2016 Nov 14;6(11):e013014corr1.


High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner.

Chambers TJG, Morgan MD, Heger AH, Sharpe RM, Drake AJ.

Sci Rep. 2016 Aug 23;6:31857. doi: 10.1038/srep31857.


Valaciclovir to prevent Cytomegalovirus mediated adverse modulation of the immune system in ANCA-associated vasculitis (CANVAS): study protocol for a randomised controlled trial.

Chanouzas D, Dyall L, Nightingale P, Ferro C, Moss P, Morgan MD, Harper L.

Trials. 2016 Jul 22;17(1):338. doi: 10.1186/s13063-016-1482-2.


Can a supported self-management program for COPD upon hospital discharge reduce readmissions? A randomized controlled trial.

Johnson-Warrington V, Rees K, Gelder C, Morgan MD, Singh SJ.

Int J Chron Obstruct Pulmon Dis. 2016 Jun 2;11:1161-9. doi: 10.2147/COPD.S91253. eCollection 2016.


Building consensus for provision of breathlessness rehabilitation for patients with chronic obstructive pulmonary disease and chronic heart failure.

Man WD, Chowdhury F, Taylor RS, Evans RA, Doherty P, Singh SJ, Booth S, Thomason D, Andrews D, Lee C, Hanna J, Morgan MD, Bell D, Cowie MR.

Chron Respir Dis. 2016 Aug;13(3):229-39. doi: 10.1177/1479972316642363. Epub 2016 Apr 12. Review.


Blood Eosinophils and Outcomes in Severe Hospitalized Exacerbations of COPD.

Bafadhel M, Greening NJ, Harvey-Dunstan TC, Williams JE, Morgan MD, Brightling CE, Hussain SF, Pavord ID, Singh SJ, Steiner MC.

Chest. 2016 Aug;150(2):320-8. doi: 10.1016/j.chest.2016.01.026. Epub 2016 Feb 3.


Fifteen-Year Survival of Endoscopic Anterior Cruciate Ligament Reconstruction in Patients Aged 18 Years and Younger.

Morgan MD, Salmon LJ, Waller A, Roe JP, Pinczewski LA.

Am J Sports Med. 2016 Feb;44(2):384-92. doi: 10.1177/0363546515623032. Epub 2016 Jan 12.


Physical Fatigue, Fitness, and Muscle Function in Patients With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

McClean A, Morgan MD, Basu N, Bosch JA, Nightingale P, Jones D, Harper L.

Arthritis Care Res (Hoboken). 2016 Sep;68(9):1332-9. doi: 10.1002/acr.22827. Epub 2016 Jul 27.


Bedside assessment of quadriceps muscle by ultrasound after admission for acute exacerbations of chronic respiratory disease.

Greening NJ, Harvey-Dunstan TC, Chaplin EJ, Vincent EE, Morgan MD, Singh SJ, Steiner MC.

Am J Respir Crit Care Med. 2015 Oct 1;192(7):810-6. doi: 10.1164/rccm.201503-0535OC.


Treatment of severe renal disease in ANCA positive and negative small vessel vasculitis with rituximab.

Shah S, Hruskova Z, Segelmark M, Morgan MD, Hogan J, Lee SK, Dale J, Harper L, Tesar V, Jayne DR, Geetha D.

Am J Nephrol. 2015;41(4-5):296-301. doi: 10.1159/000431336. Epub 2015 Jun 2.


Rituximab for treatment of severe renal disease in ANCA associated vasculitis.

Geetha D, Hruskova Z, Segelmark M, Hogan J, Morgan MD, Cavero T, Eriksson P, Seo P, Manno RL, Dale J, Harper L, Tesar V, Jayne DR.

J Nephrol. 2016 Apr;29(2):195-201. doi: 10.1007/s40620-015-0208-y. Epub 2015 May 19.


Comprehensive respiratory assessment in advanced COPD: a 'campus to clinic' translational framework.

Steiner MC, Evans RA, Greening NJ, Free RC, Woltmann G, Toms N, Morgan MD.

Thorax. 2015 Aug;70(8):805-8. doi: 10.1136/thoraxjnl-2015-206948. Epub 2015 May 11. Review. No abstract available.


Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis: 2-year results of a randomised trial.

Jones RB, Furuta S, Tervaert JW, Hauser T, Luqmani R, Morgan MD, Peh CA, Savage CO, Segelmark M, Tesar V, van Paassen P, Walsh M, Westman K, Jayne DR; European Vasculitis Society (EUVAS).

Ann Rheum Dis. 2015 Jun;74(6):1178-82. doi: 10.1136/annrheumdis-2014-206404. Epub 2015 Mar 4.


Successful outcome of pregnancy in patients with anti-neutrophil cytoplasm antibody-associated small vessel vasculitis.

Croft AP, Smith SW, Carr S, Youssouf S, Salama AD, Burns A, Pusey CD, Hamilton P, Brown N, Venning M, Harper L, Morgan MD.

Kidney Int. 2015 Apr;87(4):807-11. doi: 10.1038/ki.2014.329. Epub 2014 Oct 1.


Work productivity loss and fatigue in psoriatic arthritis.

Walsh JA, McFadden ML, Morgan MD, Sawitzke AD, Duffin KC, Krueger GG, Clegg DO.

J Rheumatol. 2014 Aug;41(8):1670-4. doi: 10.3899/jrheum.140259. Epub 2014 Jul 15.


"We are not worthy"--understanding why patients decline pulmonary rehabilitation following an acute exacerbation of COPD.

Harrison SL, Robertson N, Apps L, C Steiner M, Morgan MD, Singh SJ.

Disabil Rehabil. 2015;37(9):750-6. doi: 10.3109/09638288.2014.939770. Epub 2014 Jul 10.


An early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease: randomised controlled trial.

Greening NJ, Williams JE, Hussain SF, Harvey-Dunstan TC, Bankart MJ, Chaplin EJ, Vincent EE, Chimera R, Morgan MD, Singh SJ, Steiner MC.

BMJ. 2014 Jul 8;349:g4315. doi: 10.1136/bmj.g4315.


Ventilatory requirements of quadriceps resistance training in people with COPD and healthy controls.

Houchen-Wolloff L, Sandland CJ, Harrison SL, Menon MK, Morgan MD, Steiner MC, Singh SJ.

Int J Chron Obstruct Pulmon Dis. 2014 Jun 5;9:589-95. doi: 10.2147/COPD.S59164. eCollection 2014.


The systemic nature of chronic lung disease.

Evans RA, Morgan MD.

Clin Chest Med. 2014 Jun;35(2):283-93. doi: 10.1016/j.ccm.2014.02.009. Epub 2014 Apr 12. Review.


The role of the emphysema multidisciplinary team in a successful lung volume reduction surgery programme†.

Rathinam S, Oey I, Steiner M, Spyt T, Morgan MD, Waller DA.

Eur J Cardiothorac Surg. 2014 Dec;46(6):1021-6; discussion 1026. doi: 10.1093/ejcts/ezu129. Epub 2014 Apr 24.


MTHFR functional genetic variation and methotrexate treatment response in rheumatoid arthritis: a meta-analysis.

Morgan MD, Al-Shaarawy N, Martin S, Robinson JI, Twigg S; YEAR Consortium, Magdy AA, Omar AS, Ghattas MH, Emery P, Barrett JH, Morgan AW.

Pharmacogenomics. 2014 Mar;15(4):467-75. doi: 10.2217/pgs.13.235.


How do informal self-care strategies evolve among patients with chronic obstructive pulmonary disease managed in primary care? A qualitative study.

Apps LD, Harrison SL, Williams JE, Hudson N, Steiner M, Morgan MD, Singh SJ.

Int J Chron Obstruct Pulmon Dis. 2014 Feb 26;9:257-63. doi: 10.2147/COPD.S52691. eCollection 2014.


The British Thoracic Society guideline on pulmonary rehabilitation in adults: your opinion is noted.

Bolton CE, Blakey JD, Morgan MD; BTS Pulmonary Rehabilitation Guideline Development Group for the Standards of Care Committee for the BTS.

Thorax. 2014 Apr;69(4):388-9. doi: 10.1136/thoraxjnl-2013-204754. Epub 2014 Jan 15. No abstract available.


Can we identify patients with different illness schema following an acute exacerbation of COPD: a cluster analysis.

Harrison SL, Robertson N, Graham CD, Williams J, Steiner MC, Morgan MD, Singh SJ.

Respir Med. 2014 Feb;108(2):319-28. doi: 10.1016/j.rmed.2013.10.016. Epub 2013 Oct 30.


'Consumed by breathing' - a critical interpretive meta-synthesis of the qualitative literature.

Harrison SL, Apps L, Singh SJ, Steiner MC, Morgan MD, Robertson N.

Chronic Illn. 2014 Mar;10(1):31-49. doi: 10.1177/1742395313493122. Epub 2013 Nov 13.


Physical activity monitoring: addressing the difficulties of accurately detecting slow walking speeds.

Harrison SL, Horton EJ, Smith R, Sandland CJ, Steiner MC, Morgan MD, Singh SJ.

Heart Lung. 2013 Sep-Oct;42(5):361-4.e1. doi: 10.1016/j.hrtlng.2013.06.004.


Age-specific normal values for the incremental shuttle walk test in a healthy British population.

Harrison SL, Greening NJ, Houchen-Wolloff L, Bankart J, Morgan MD, Steiner MC, Singh SJ.

J Cardiopulm Rehabil Prev. 2013 Sep-Oct;33(5):309-13. doi: 10.1097/HCR.0b013e3182a0297e.


British Thoracic Society guideline on pulmonary rehabilitation in adults.

Bolton CE, Bevan-Smith EF, Blakey JD, Crowe P, Elkin SL, Garrod R, Greening NJ, Heslop K, Hull JH, Man WD, Morgan MD, Proud D, Roberts CM, Sewell L, Singh SJ, Walker PP, Walmsley S; British Thoracic Society Pulmonary Rehabilitation Guideline Development Group; British Thoracic Society Standards of Care Committee.

Thorax. 2013 Sep;68 Suppl 2:ii1-30. doi: 10.1136/thoraxjnl-2013-203808. No abstract available.


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