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Mesenchymal stem cells gene signature in high-risk myeloma bone marrow linked to suppression of distinct IGFBP2-expressing small adipocytes.

Mehdi SJ, Johnson SK, Epstein J, Zangari M, Qu P, Hoering A, van Rhee F, Schinke C, Thanendrarajan S, Barlogie B, Davies FE, Morgan GJ, Yaccoby S.

Br J Haematol. 2018 Nov 8. doi: 10.1111/bjh.15669. [Epub ahead of print]


Editorial: Language Acquisition in Diverse Linguistic, Social and Cognitive Circumstances.

Garraffa M, Guasti MT, Marinis T, Morgan G.

Front Psychol. 2018 Oct 24;9:1807. doi: 10.3389/fpsyg.2018.01807. eCollection 2018. No abstract available.


Legal capacity, mental capacity and supported decision-making: Report from a panel event.

Craigie J, Bach M, Gurbai S, Kanter A, Kim SYH, Lewis O, Morgan G.

Int J Law Psychiatry. 2018 Oct 31. pii: S0160-2527(18)30154-7. doi: 10.1016/j.ijlp.2018.09.006. [Epub ahead of print] Review.


Sub-clonal TP53 copy number is associated with prognosis in multiple myeloma.

Shah V, Johnson DC, Sherborne AL, Ellis S, Aldridge FM, Howard-Reeves J, Begum F, Price A, Kendall J, Chiecchio L, Savola S, Jenner MW, Drayson MT, Owen RG, Gregory WM, Morgan GJ, Davies FE, Houlston RS, Cook G, Cairns DA, Jackson G, Kaiser MF.

Blood. 2018 Oct 29. pii: blood-2018-06-857250. doi: 10.1182/blood-2018-06-857250. [Epub ahead of print]


Using in vitro model to assess stent-stent interaction in patients with coronary artery compression.

Zablah JE, Fry R, Ross M, Wilson N, Morgan G.

J Interv Cardiol. 2018 Oct 28. doi: 10.1111/joic.12565. [Epub ahead of print]


Development of New Formulations of Biologics: Expectations, Immunogenicity, and Safety for Subcutaneous Trastuzumab.

Pimentel FF, Morgan G, Tiezzi DG, de Andrade JM.

Pharmaceut Med. 2018;32(5):319-325. doi: 10.1007/s40290-018-0247-5. Epub 2018 Sep 24.


Serum biomarkers of glucocorticoid response and safety in anti-neutrophil cytoplasmic antibody-associated vasculitis and juvenile dermatomyositis.

Conklin LS, Merkel PA, Pachman LM, Parikh H, Tawalbeh S, Damsker JM, Cuthbertson DD, Morgan GA, Monach PA, Hathout Y, Nagaraju K, van den Anker J, McAlear CA, Hoffman EP.

Steroids. 2018 Oct 21;140:159-166. doi: 10.1016/j.steroids.2018.10.008. [Epub ahead of print]


SAPIEN valve for percutaneous transcatheter pulmonary valve replacement without "pre-stenting": A multi-institutional experience.

Morgan GJ, Sadeghi S, Salem MM, Wilson N, Kay J, Rothman A, Galindo A, Martin MH, Gray R, Ross M, Aboulhosn JA, Levi DS.

Catheter Cardiovasc Interv. 2018 Oct 23. doi: 10.1002/ccd.27932. [Epub ahead of print]


Infective Endocarditis, a Rare Complication of Late Neonatal Group B Strep Sepsis.

McLennan D, Morgan G.

Front Pediatr. 2018 Oct 3;6:274. doi: 10.3389/fped.2018.00274. eCollection 2018.


Ambient particulate matter and paramedic assessments of acute diabetic, cardiovascular, respiratory conditions.

Johnston FH, Salimi F, Williamson GJ, Henderson SB, Yao J, Dennekamp M, Smith K, Abramson MJ, Morgan GG.

Epidemiology. 2018 Oct 16. doi: 10.1097/EDE.0000000000000929. [Epub ahead of print]


Management of post-myocardial infarction ventricular septal defects: A critical assessment.

Omar S, Morgan GL, Panchal HB, Thourani V, Rihal CS, Patel R, Kherada N, Egbe AC, Beohar N.

J Interv Cardiol. 2018 Aug 28. doi: 10.1111/joic.12556. [Epub ahead of print] Review.


Satellite-based land-use regression for continental-scale long-term ambient PM2.5 exposure assessment in Australia.

Knibbs LD, van Donkelaar A, Martin RV, Bechle MJ, Brauer M, Cohen D, Cowie CT, Dirgawati M, Guo Y, Hanigan I, Johnston F, Marks GB, Marshall JD, Pereira G, Jalaludin B, Heyworth JS, Morgan G, Barnett A.

Environ Sci Technol. 2018 Oct 2. doi: 10.1021/acs.est.8b02328. [Epub ahead of print]


Restoration of cellular integrity following "ballistic" pronuclear exchange during Tetrahymena conjugation.

Cole ES, Dmytrenko O, Chmelik CJ, Li M, Christensen TA, Macon EP, Nilsson HJ, Blower RJ, Reuter TG, Beckman JP, Remmers BC, Smith CL, O'Toole E, Ozzello C, Morgan G, Giddings T.

Dev Biol. 2018 Dec 1;444(1):33-40. doi: 10.1016/j.ydbio.2018.09.019. Epub 2018 Sep 27.


Is Mastery Motivation a Mediator of Relations between Maternal Teaching Behavior and Developmental Abilities in Children with Global Developmental Delay?

Wang PJ, Chen LC, Liao HF, Tu YK, Lu L, Morgan GA.

Phys Occup Ther Pediatr. 2018 Sep 28:1-18. doi: 10.1080/01942638.2018.1505800. [Epub ahead of print]


Long-term exposure to low concentrations of air pollutants and hospitalisation for respiratory diseases: A prospective cohort study in Australia.

Salimi F, Morgan G, Rolfe M, Samoli E, Cowie CT, Hanigan I, Knibbs L, Cope M, Johnston FH, Guo Y, Marks GB, Heyworth J, Jalaludin B.

Environ Int. 2018 Dec;121(Pt 1):415-420. doi: 10.1016/j.envint.2018.08.050. Epub 2018 Sep 25.


Characterization of retinal regeneration in adult zebrafish following multiple rounds of phototoxic lesion.

Ranski AH, Kramer AC, Morgan GW, Perez JL, Thummel R.

PeerJ. 2018 Sep 20;6:e5646. doi: 10.7717/peerj.5646. eCollection 2018.


A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis.

Bødker JS, Brøndum RF, Schmitz A, Schönherz AA, Jespersen DS, Sønderkær M, Vesteghem C, Due H, Nørgaard CH, Perez-Andres M, Samur MK, Davies F, Walker B, Pawlyn C, Kaiser M, Johnson D, Bertsch U, Broyl A, van Duin M, Shah R, Johansen P, Nørgaard MA, Samworth RJ, Sonneveld P, Goldschmidt H, Morgan GJ, Orfao A, Munshi N, Johnson HE, El-Galaly T, Dybkær K, Bøgsted M.

Blood Adv. 2018 Sep 25;2(18):2400-2411. doi: 10.1182/bloodadvances.2018018564.


Systematic review update of observational studies further supports aspirin role in cancer treatment: Time to share evidence and decision-making with patients?

Elwood PC, Pickering JE, Morgan G, Galante J, Weightman AL, Morris D, Longley M, Mason M, Adams R, Dolwani S, Chia W K J, Lanas A.

PLoS One. 2018 Sep 25;13(9):e0203957. doi: 10.1371/journal.pone.0203957. eCollection 2018.


Medium-Term Results of Percutaneous Pulmonary Valve Implantation using The Venus P-valve™: international experience.

Morgan G, Prachasilchai P, Promphan W, Rosenthal E, Sivakumar K, Kappanayil M, Sakidjan I, Walsh KP, Kenny D, Thomson J, Koneti N, Awasthy N, Thanopoulos B, Roymanee S, Qureshi S.

EuroIntervention. 2018 Sep 25. pii: EIJ-D-18-00299. doi: 10.4244/EIJ-D-18-00299. [Epub ahead of print]


FRAX is a robust predictor of baseline vertebral fractures in multiple myeloma patients.

Atrash S, Dua I, Buros AF, Van Rhee F, Suva LJ, Thanendrarajan S, Schinke C, Davies F, Morgan G, Zangari M.

Bone. 2018 Sep 19. pii: S8756-3282(18)30353-3. doi: 10.1016/j.bone.2018.09.013. [Epub ahead of print]


The role of mechanical bowel preparation and oral antibiotics for left-sided laparoscopic and open elective restorative colorectal surgery with and without faecal diversion.

Toh JWT, Phan K, Ctercteko G, Pathma-Nathan N, El-Khoury T, Richardson A, Morgan G, Tang R, Zeng M, Donovan S, Chu D, Kennedy G, Hitos K.

Int J Colorectal Dis. 2018 Dec;33(12):1781-1791. doi: 10.1007/s00384-018-3166-8. Epub 2018 Sep 20.


Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Went M, Sud A, Försti A, Halvarsson BM, Weinhold N, Kimber S, van Duin M, Thorleifsson G, Holroyd A, Johnson DC, Li N, Orlando G, Law PJ, Ali M, Chen B, Mitchell JS, Gudbjartsson DF, Kuiper R, Stephens OW, Bertsch U, Broderick P, Campo C, Bandapalli OR, Einsele H, Gregory WA, Gullberg U, Hillengass J, Hoffmann P, Jackson GH, Jöckel KH, Johnsson E, Kristinsson SY, Mellqvist UH, Nahi H, Easton D, Pharoah P, Dunning A, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N, Nickel J, Nöthen MM, Rafnar T, Ross FM, da Silva Filho MI, Thomsen H, Turesson I, Vangsted A, Andersen NF, Waage A, Walker BA, Wihlborg AK, Broyl A, Davies FE, Thorsteinsdottir U, Langer C, Hansson M, Goldschmidt H, Kaiser M, Sonneveld P, Stefansson K, Morgan GJ, Hemminki K, Nilsson B, Houlston RS; PRACTICAL consortium.

Nat Commun. 2018 Sep 13;9(1):3707. doi: 10.1038/s41467-018-04989-w.


What we talk about when we talk about investment in mental health.

Morgan G.

Lancet Psychiatry. 2018 Sep;5(9):695-696. doi: 10.1016/S2215-0366(18)30210-4. No abstract available.


Variation in Anticoagulation Practices in the Congenital Cardiac Catheterization Lab: Results of a Multinational PICES Survey.

Taggart NW, Gordon BM, Morgan GJ, Goldstein BH.

Pediatr Cardiol. 2018 Aug 18. doi: 10.1007/s00246-018-1960-2. [Epub ahead of print]


Maintenance Treatment and Survival in Patients With Myeloma: A Systematic Review and Network Meta-analysis.

Gay F, Jackson G, Rosiñol L, Holstein SA, Moreau P, Spada S, Davies F, Lahuerta JJ, Leleu X, Bringhen S, Evangelista A, Hulin C, Panzani U, Cairns DA, Di Raimondo F, Macro M, Liberati AM, Pawlyn C, Offidani M, Spencer A, Hájek R, Terpos E, Morgan GJ, Bladé J, Sonneveld P, San-Miguel J, McCarthy PL, Ludwig H, Boccadoro M, Mateos MV, Attal M.

JAMA Oncol. 2018 Oct 1;4(10):1389-1397. doi: 10.1001/jamaoncol.2018.2961.


Spin Crossover Behavior in a Homologous Series of Iron(II) Complexes Based on Functionalized Bipyridyl Ligands.

Xue S, Guo Y, Rotaru A, Müller-Bunz H, Morgan GG, Trzop E, Collet E, Oláh J, Garcia Y.

Inorg Chem. 2018 Aug 20;57(16):9880-9891. doi: 10.1021/acs.inorgchem.8b00850. Epub 2018 Aug 6.


Discovery of (Dihydro)pyrazine N-Oxides via Genome Mining in Pseudomonas.

Kretsch AM, Morgan GL, Tyrrell J, Mevers E, Vallet-Gély I, Li B.

Org Lett. 2018 Aug 17;20(16):4791-4795. doi: 10.1021/acs.orglett.8b01944. Epub 2018 Aug 3.


Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability.

Dutta AK, Fink JL, Grady JP, Morgan GJ, Mullighan CG, To LB, Hewett DR, Zannettino ACW.

Leukemia. 2018 Jul 25. doi: 10.1038/s41375-018-0206-x. [Epub ahead of print]


Pulmonary Regurgitation- Is the Future Percutaneous or Surgical?

Morgan GJ.

Front Pediatr. 2018 Jul 10;6:184. doi: 10.3389/fped.2018.00184. eCollection 2018. Review.


Pregnancy Outcomes Reported During the 13-Year TREAT Registry: A Descriptive Report.

Lichtenstein GR, Feagan BG, Mahadevan U, Salzberg BA, Langholff W, Morgan GJ, Safdi M, Nissinen R, Taillard F, Sandborn WJ, Cohen RD.

Am J Gastroenterol. 2018 Jul 19. doi: 10.1038/s41395-018-0202-9. [Epub ahead of print]


Serum free light chain levels and renal function at diagnosis in patients with multiple myeloma.

Yadav P, Cockwell P, Cook M, Pinney J, Giles H, Aung YS, Cairns D, Owen RG, Davies FE, Jackson GH, Child JA, Morgan GJ, Drayson MT.

BMC Nephrol. 2018 Jul 13;19(1):178. doi: 10.1186/s12882-018-0962-x.


Noninvasive wave intensity analysis predicts functional worsening in children with pulmonary arterial hypertension.

Schäfer M, Wilson N, Ivy DD, Ing R, Abman S, Browne LP, Morgan G, Ross M, McLennan D, Barker AJ, Fonseca B, Di Maria M, Hunter KS, Truong U.

Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H968-H977. doi: 10.1152/ajpheart.00227.2018. Epub 2018 Jul 13.


Precision Mass Measurements of Neutron-Rich Neodymium and Samarium Isotopes and Their Role in Understanding Rare-Earth Peak Formation.

Orford R, Vassh N, Clark JA, McLaughlin GC, Mumpower MR, Savard G, Surman R, Aprahamian A, Buchinger F, Burkey MT, Gorelov DA, Hirsh TY, Klimes JW, Morgan GE, Nystrom A, Sharma KS.

Phys Rev Lett. 2018 Jun 29;120(26):262702. doi: 10.1103/PhysRevLett.120.262702.


Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised study.

Royle KL, Gregory WM, Cairns DA, Bell SE, Cook G, Owen RG, Drayson MT, Davies FE, Jackson GH, Morgan GJ, Child JA.

Br J Haematol. 2018 Sep;182(6):816-829. doi: 10.1111/bjh.15459. Epub 2018 Jul 9.


MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.

Qiang YW, Ye S, Huang Y, Chen Y, Van Rhee F, Epstein J, Walker BA, Morgan GJ, Davies FE.

BMC Cancer. 2018 Jul 6;18(1):724. doi: 10.1186/s12885-018-4602-4.


A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.

Walker BA, Mavrommatis K, Wardell CP, Ashby TC, Bauer M, Davies F, Rosenthal A, Wang H, Qu P, Hoering A, Samur M, Towfic F, Ortiz M, Flynt E, Yu Z, Yang Z, Rozelle D, Obenauer J, Trotter M, Auclair D, Keats J, Bolli N, Fulciniti M, Szalat R, Moreau P, Durie B, Stewart AK, Goldschmidt H, Raab MS, Einsele H, Sonneveld P, San Miguel J, Lonial S, Jackson GH, Anderson KC, Avet-Loiseau H, Munshi N, Thakurta A, Morgan G.

Leukemia. 2018 Jul 2. doi: 10.1038/s41375-018-0196-8. [Epub ahead of print]


Three-Dimensional Echocardiographic Guidance of Right Heart Catheterization Decreases Radiation Exposure in Atrial Septal Defect Closures.

Jone PN, Zablah JE, Burkett DA, Schäfer M, Wilson N, Morgan GJ, Ross M.

J Am Soc Echocardiogr. 2018 Sep;31(9):1044-1049. doi: 10.1016/j.echo.2018.04.016. Epub 2018 Jun 27.


Maintaining therapeutic progress in multiple myeloma by integrating genetic and biological advances into the clinic.

Morgan GJ, Rasche L.

Expert Rev Hematol. 2018 Jul;11(7):513-523. doi: 10.1080/17474086.2018.1489718. Epub 2018 Jun 26.


Characterisation of immunoparesis in newly diagnosed myeloma and its impact on progression-free and overall survival in both old and recent myeloma trials.

Heaney JLJ, Campbell JP, Iqbal G, Cairns D, Richter A, Child JA, Gregory W, Jackson G, Kaiser M, Owen R, Davies F, Morgan G, Dunn J, Drayson MT.

Leukemia. 2018 Aug;32(8):1727-1738. doi: 10.1038/s41375-018-0163-4. Epub 2018 Jun 20.


Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.

Walker BA, Mavrommatis K, Wardell CP, Ashby TC, Bauer M, Davies FE, Rosenthal A, Wang H, Qu P, Hoering A, Samur M, Towfic F, Ortiz M, Flynt E, Yu Z, Yang Z, Rozelle D, Obenauer J, Trotter M, Auclair D, Keats J, Bolli N, Fulciniti M, Szalat R, Moreau P, Durie B, Stewart AK, Goldschmidt H, Raab MS, Einsele H, Sonneveld P, San Miguel J, Lonial S, Jackson GH, Anderson KC, Avet-Loiseau H, Munshi N, Thakurta A, Morgan GJ.

Blood. 2018 Aug 9;132(6):587-597. doi: 10.1182/blood-2018-03-840132. Epub 2018 Jun 8. Erratum in: Blood. 2018 Sep 27;132(13):1461.


Electron Microscopy Imaging of Zinc Soaps Nucleation in Oil Paint.

Hermans J, Osmond G, van Loon A, Iedema P, Chapman R, Drennan J, Jack K, Rasch R, Morgan G, Zhang Z, Monteiro M, Keune K.

Microsc Microanal. 2018 Jun;24(3):318-322. doi: 10.1017/S1431927618000387. Epub 2018 Jun 4.


Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments.

McIntosh JR, O'Toole E, Morgan G, Austin J, Ulyanov E, Ataullakhanov F, Gudimchuk N.

J Cell Biol. 2018 Aug 6;217(8):2691-2708. doi: 10.1083/jcb.201802138. Epub 2018 May 23.


Cardiovascular Screening Practices and Attitudes From the NCAA Autonomous "Power" 5 Conferences.

Miars CW, Stamatis A, Morgan GB, Drezner JA.

Sports Health. 2018 Nov/Dec;10(6):547-551. doi: 10.1177/1941738118775039. Epub 2018 May 24.


The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma.

Rasche L, Angtuaco EJ, Alpe TL, Gershner GH, McDonald JE, Samant RS, Kumar M, Van Hemert R, Epstein J, Deshpande S, Tytarenko R, Yaccoby S, Hillengass J, Thanendrarajan S, Schinke C, van Rhee F, Zangari M, Walker BA, Barlogie B, Morgan GJ, Davies FE, Weinhold N.

Blood. 2018 Jul 5;132(1):59-66. doi: 10.1182/blood-2018-04-842880. Epub 2018 May 21.


Long term extension of a randomised controlled trial of probiotics using electronic health records.

Davies G, Jordan S, Brooks CJ, Thayer D, Storey M, Morgan G, Allen S, Garaiova I, Plummer S, Gravenor M.

Sci Rep. 2018 May 16;8(1):7668. doi: 10.1038/s41598-018-25954-z.


Evaluation of a modified Cheatham-Platinum stent for the treatment of aortic coarctation by finite element modelling.

Burkhardt BE, Byrne N, Velasco Forte MN, Iannaccone F, De Beule M, Morgan GJ, Hussain T.

JRSM Cardiovasc Dis. 2018 Apr 27;7:2048004018773958. doi: 10.1177/2048004018773958. eCollection 2018 Jan-Dec.


The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression.

Ali M, Ajore R, Wihlborg AK, Niroula A, Swaminathan B, Johnsson E, Stephens OW, Morgan G, Meissner T, Turesson I, Goldschmidt H, Mellqvist UH, Gullberg U, Hansson M, Hemminki K, Nahi H, Waage A, Weinhold N, Nilsson B.

Nat Commun. 2018 Apr 25;9(1):1649. doi: 10.1038/s41467-018-04082-2.


Aortic stiffness in adolescent Turner and Marfan syndrome patients.

Schäfer M, Browne LP, Truong U, Jaggers JJ, Mitchell MB, Malone L, Morgan G, Chatfield K, McLennan D, Turbendian H, Vargas D, Fonseca B, DiMaria M, Shah A, Ivy MP, Barker AJ, Hunter KS, Wilson N, Ivy DD, Campbell DN.

Eur J Cardiothorac Surg. 2018 Nov 1;54(5):926-932. doi: 10.1093/ejcts/ezy168.


Impact of different coarctation therapies on aortic stiffness: phase-contrast MRI study.

Schäfer M, Morgan GJ, Mitchell MB, Ross M, Barker AJ, Hunter KS, Fonseca B, DiMaria M, Vargas D, Ivy DD, Wilson N, Browne LP.

Int J Cardiovasc Imaging. 2018 Sep;34(9):1459-1469. doi: 10.1007/s10554-018-1357-6. Epub 2018 Apr 17.


Kinase domain activation through gene rearrangement in multiple myeloma.

Morgan GJ, He J, Tytarenko R, Patel P, Stephens OW, Zhong S, Deshpande S, Bauer M, Weinhold N, Schinke C, Rasche L, Bailey M, Ali S, Ross J, Miller VA, Stephens P, Thanendrarajan S, Zangari M, van Rhee F, Mughal T, Davies FE, Walker BA.

Leukemia. 2018 Nov;32(11):2435-2444. doi: 10.1038/s41375-018-0108-y. Epub 2018 Mar 23.

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