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Items: 8

1.

Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice.

Pucilowska J, Vithayathil J, Pagani M, Kelly C, Karlo JC, Robol C, Morella I, Gozzi A, Brambilla R, Landreth GE.

J Neurosci. 2018 Jul 25;38(30):6640-6652. doi: 10.1523/JNEUROSCI.0515-17.2018. Epub 2018 Jun 22.

PMID:
29934348
2.

Anti-Parkinsonian and anti-dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists.

Arcuri L, Novello S, Frassineti M, Mercatelli D, Pisanò CA, Morella I, Fasano S, Journigan BV, Meyer ME, Polgar WE, Brambilla R, Zaveri NT, Morari M.

Br J Pharmacol. 2018 Mar;175(5):782-796. doi: 10.1111/bph.14123. Epub 2018 Jan 31.

PMID:
29232769
3.

Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors.

Papale A, Morella IM, Indrigo MT, Bernardi RE, Marrone L, Marchisella F, Brancale A, Spanagel R, Brambilla R, Fasano S.

Elife. 2016 Aug 24;5. pii: e17111. doi: 10.7554/eLife.17111.

4.

Coordinated Regulation of Synaptic Plasticity at Striatopallidal and Striatonigral Neurons Orchestrates Motor Control.

Trusel M, Cavaccini A, Gritti M, Greco B, Saintot PP, Nazzaro C, Cerovic M, Morella I, Brambilla R, Tonini R.

Cell Rep. 2015 Nov 17;13(7):1353-1365. doi: 10.1016/j.celrep.2015.10.009. Epub 2015 Nov 5.

5.

Differential allelic expression of SOS1 and hyperexpression of the activating SOS1 c.755C variant in a Noonan syndrome family.

Moncini S, Bonati MT, Morella I, Ferrari L, Brambilla R, Riva P.

Eur J Hum Genet. 2015 Nov;23(11):1531-7. doi: 10.1038/ejhg.2015.20. Epub 2015 Feb 25.

6.

Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia.

Cerovic M, Bagetta V, Pendolino V, Ghiglieri V, Fasano S, Morella I, Hardingham N, Heuer A, Papale A, Marchisella F, GiampĂ  C, Calabresi P, Picconi B, Brambilla R.

Biol Psychiatry. 2015 Jan 15;77(2):106-15. doi: 10.1016/j.biopsych.2014.04.002. Epub 2014 Apr 12.

PMID:
24844602
7.

Nociceptin/orphanin FQ receptor agonists attenuate L-DOPA-induced dyskinesias.

Marti M, Rodi D, Li Q, Guerrini R, Fasano S, Morella I, Tozzi A, Brambilla R, Calabresi P, Simonato M, Bezard E, Morari M.

J Neurosci. 2012 Nov 14;32(46):16106-19. doi: 10.1523/JNEUROSCI.6408-11.2012.

8.

Noonan syndrome associated with both a new Jnk-activating familial SOS1 and a de novo RAF1 mutations.

Longoni M, Moncini S, Cisternino M, Morella IM, Ferraiuolo S, Russo S, Mannarino S, Brazzelli V, Coi P, Zippel R, Venturin M, Riva P.

Am J Med Genet A. 2010 Sep;152A(9):2176-84. doi: 10.1002/ajmg.a.33564.

PMID:
20683980

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