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Items: 16


Efficient TALEN-mediated gene editing in wheat.

Luo M, Li H, Chakraborty S, Morbitzer R, Rinaldo A, Upadhyaya N, Bhatt D, Louis S, Richardson T, Lahaye T, Ayliffe M.

Plant Biotechnol J. 2019 Nov;17(11):2026-2028. doi: 10.1111/pbi.13169. Epub 2019 Jun 6. No abstract available.


TALE-induced bHLH transcription factors that activate a pectate lyase contribute to water soaking in bacterial spot of tomato.

Schwartz AR, Morbitzer R, Lahaye T, Staskawicz BJ.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E897-E903. doi: 10.1073/pnas.1620407114. Epub 2017 Jan 18.


A simple test for the cleavage activity of customized endonucleases in plants.

Budhagatapalli N, Schedel S, Gurushidze M, Pencs S, Hiekel S, Rutten T, Kusch S, Morbitzer R, Lahaye T, Panstruga R, Kumlehn J, Hensel G.

Plant Methods. 2016 Mar 9;12:18. doi: 10.1186/s13007-016-0118-6. eCollection 2016.


Comparison of gene activation by two TAL effectors from Xanthomonas axonopodis pv. manihotis reveals candidate host susceptibility genes in cassava.

Cohn M, Morbitzer R, Lahaye T, Staskawicz BJ.

Mol Plant Pathol. 2016 Aug;17(6):875-89. doi: 10.1111/mpp.12337. Epub 2016 Feb 8.


TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines.

Müller TM, Böttcher C, Morbitzer R, Götz CC, Lehmann J, Lahaye T, Glawischnig E.

Plant Physiol. 2015 Jul;168(3):849-58. doi: 10.1104/pp.15.00481. Epub 2015 May 7.


Xanthomonas axonopodis virulence is promoted by a transcription activator-like effector-mediated induction of a SWEET sugar transporter in cassava.

Cohn M, Bart RS, Shybut M, Dahlbeck D, Gomez M, Morbitzer R, Hou BH, Frommer WB, Lahaye T, Staskawicz BJ.

Mol Plant Microbe Interact. 2014 Nov;27(11):1186-98. doi: 10.1094/MPMI-06-14-0161-R.


Programmable DNA-binding proteins from Burkholderia provide a fresh perspective on the TALE-like repeat domain.

de Lange O, Wolf C, Dietze J, Elsaesser J, Morbitzer R, Lahaye T.

Nucleic Acids Res. 2014 Jun;42(11):7436-49. doi: 10.1093/nar/gku329. Epub 2014 May 3.


TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity.

Mussolino C, Alzubi J, Fine EJ, Morbitzer R, Cradick TJ, Lahaye T, Bao G, Cathomen T.

Nucleic Acids Res. 2014 Jun;42(10):6762-73. doi: 10.1093/nar/gku305. Epub 2014 May 3.


A modular plasmid assembly kit for multigene expression, gene silencing and silencing rescue in plants.

Binder A, Lambert J, Morbitzer R, Popp C, Ott T, Lahaye T, Parniske M.

PLoS One. 2014 Feb 13;9(2):e88218. doi: 10.1371/journal.pone.0088218. eCollection 2014.


Targeting and tracing of specific DNA sequences with dTALEs in living cells.

Thanisch K, Schneider K, Morbitzer R, Solovei I, Lahaye T, Bultmann S, Leonhardt H.

Nucleic Acids Res. 2014 Apr;42(6):e38. doi: 10.1093/nar/gkt1348. Epub 2013 Dec 25.


Quantitative analysis of TALE-DNA interactions suggests polarity effects.

Meckler JF, Bhakta MS, Kim MS, Ovadia R, Habrian CH, Zykovich A, Yu A, Lockwood SH, Morbitzer R, Elsäesser J, Lahaye T, Segal DJ, Baldwin EP.

Nucleic Acids Res. 2013 Apr;41(7):4118-28. doi: 10.1093/nar/gkt085. Epub 2013 Feb 13.


Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers.

Bultmann S, Morbitzer R, Schmidt CS, Thanisch K, Spada F, Elsaesser J, Lahaye T, Leonhardt H.

Nucleic Acids Res. 2012 Jul;40(12):5368-77. doi: 10.1093/nar/gks199. Epub 2012 Mar 2.


A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

Mussolino C, Morbitzer R, Lütge F, Dannemann N, Lahaye T, Cathomen T.

Nucleic Acids Res. 2011 Nov;39(21):9283-93. doi: 10.1093/nar/gkr597. Epub 2011 Aug 3.


Assembly of custom TALE-type DNA binding domains by modular cloning.

Morbitzer R, Elsaesser J, Hausner J, Lahaye T.

Nucleic Acids Res. 2011 Jul;39(13):5790-9. doi: 10.1093/nar/gkr151. Epub 2011 Mar 18.


Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors.

Morbitzer R, Römer P, Boch J, Lahaye T.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21617-22. doi: 10.1073/pnas.1013133107. Epub 2010 Nov 24.


Recognition of AvrBs3-like proteins is mediated by specific binding to promoters of matching pepper Bs3 alleles.

Römer P, Strauss T, Hahn S, Scholze H, Morbitzer R, Grau J, Bonas U, Lahaye T.

Plant Physiol. 2009 Aug;150(4):1697-712. doi: 10.1104/pp.109.139931. Epub 2009 May 15.

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