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Items: 38

1.

Mycobacteriophage CRB2 defines a new subcluster in mycobacteriophage classification.

Suarez CA, Franceschelli JJ, Morbidoni HR.

PLoS One. 2019 Feb 27;14(2):e0212365. doi: 10.1371/journal.pone.0212365. eCollection 2019.

2.

Deletion of MSMEG_1350 in Mycobacterium smegmatis causes loss of epoxy-mycolic acids, fitness alteration at low temperature and resistance to a set of mycobacteriophages.

Di Capua CB, Belardinelli JM, Buchieri MV, Bortolotti A, Franceschelli JJ, Morbidoni HR.

Microbiology. 2018 Dec;164(12):1567-1582. doi: 10.1099/mic.0.000734. Epub 2018 Oct 12.

PMID:
30311878
3.

A katG S315T or an ahpC promoter mutation mediate Mycobacterium tuberculosis resistance to 2-thiophen carboxylic acid hydrazide, an inhibitor resembling the anti-tubercular drugs Isoniazid and Ethionamide.

Franceschelli JJ, Belardinelli JM, Tong P, Loftus B, Recio-Balsells A, Labadié GR, Gordon SV, Morbidoni HR.

Tuberculosis (Edinb). 2018 Sep;112:69-78. doi: 10.1016/j.tube.2018.08.001. Epub 2018 Aug 3.

PMID:
30205971
4.

Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis.

Muradás TC, Abbadi BL, Villela AD, Macchi FS, Bergo PF, de Freitas TF, Sperotto NDM, Timmers LFSM, Norberto de Souza O, Picada JN, Fachini J, da Silva JB, de Albuquerque NCP, Habenschus MD, Carrão DB, Rocha BA, Barbosa Junior F, de Oliveira ARM, Mascarello A, Neuenfeldf P, Nunes RJ, Morbidoni HR, Campos MM, Basso LA, Rodrigues-Junior VS.

PLoS One. 2018 Aug 16;13(8):e0202568. doi: 10.1371/journal.pone.0202568. eCollection 2018.

5.

Correction: Broad-range lytic bacteriophages that kill Staphylococcus aureus local field strains.

Abatángelo V, Peressutti Bacci N, Boncompain CA, Amadio AF, Carrasco S, Suárez CA, Morbidoni HR.

PLoS One. 2017 Oct 27;12(10):e0187387. doi: 10.1371/journal.pone.0187387. eCollection 2017.

6.

Complete auxotrophy for unsaturated fatty acids requires deletion of two sets of genes in Mycobacterium smegmatis.

Di Capua CB, Doprado M, Belardinelli JM, Morbidoni HR.

Mol Microbiol. 2017 Oct;106(1):93-108. doi: 10.1111/mmi.13753. Epub 2017 Aug 11.

7.

Broad-range lytic bacteriophages that kill Staphylococcus aureus local field strains.

Abatángelo V, Peressutti Bacci N, Boncompain CA, Amadio AF, Carrasco S, Suárez CA, Morbidoni HR.

PLoS One. 2017 Jul 25;12(7):e0181671. doi: 10.1371/journal.pone.0181671. eCollection 2017. Erratum in: PLoS One. 2017 Oct 27;12 (10 ):e0187387.

8.

Staphylococcus aureus nasal carriage in health care workers: First report from a major public hospital in Argentina.

Boncompain CA, Suárez CA, Morbidoni HR.

Rev Argent Microbiol. 2017 Apr - Jun;49(2):125-131. doi: 10.1016/j.ram.2016.12.007. Epub 2017 Mar 24.

9.

Antitubercular activity of 1,2,3-triazolyl fatty acid derivatives.

Ghiano DG, de la Iglesia A, Liu N, Tonge PJ, Morbidoni HR, Labadie GR.

Eur J Med Chem. 2017 Jan 5;125:842-852. doi: 10.1016/j.ejmech.2016.09.086. Epub 2016 Sep 28.

10.

Anti-tubercular and antioxidant activities of C-glycosyl carbonic anhydrase inhibitors: towards the development of novel chemotherapeutic agents against Mycobacterium tuberculosis.

Zaro MJ, Bortolotti A, Riafrecha LE, Concellón A, Morbidoni HR, Colinas PA.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1726-30. doi: 10.3109/14756366.2016.1172577. Epub 2016 May 5.

PMID:
27146440
11.

Complete genome sequences of nine mycobacteriophages.

Franceschelli JJ, Suarez CA, Terán L, Raya RR, Morbidoni HR.

Genome Announc. 2014 May 29;2(3). pii: e00181-14. doi: 10.1128/genomeA.00181-14.

12.

IQG-607 abrogates the synthesis of mycolic acids and displays intracellular activity against Mycobacterium tuberculosis in infected macrophages.

Rodrigues-Junior VS, dos Santos Junior AA, Villela AD, Belardinelli JM, Morbidoni HR, Basso LA, Campos MM, Santos DS.

Int J Antimicrob Agents. 2014 Jan;43(1):82-5. doi: 10.1016/j.ijantimicag.2013.08.021. Epub 2013 Oct 1.

PMID:
24139881
13.

Recycling and refurbishing old antitubercular drugs: the encouraging case of inhibitors of mycolic acid biosynthesis.

Belardinelli JM, Morbidoni HR.

Expert Rev Anti Infect Ther. 2013 Apr;11(4):429-40. doi: 10.1586/eri.13.24. Review.

PMID:
23566152
14.

Analysis of novel mycobacteriophages indicates the existence of different strategies for phage inheritance in mycobacteria.

Stella EJ, Franceschelli JJ, Tasselli SE, Morbidoni HR.

PLoS One. 2013;8(2):e56384. doi: 10.1371/journal.pone.0056384. Epub 2013 Feb 28.

15.

Inhibition of the β-carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides: identification of the first inhibitor with anti-mycobacterial activity.

Buchieri MV, Riafrecha LE, Rodríguez OM, Vullo D, Morbidoni HR, Supuran CT, Colinas PA.

Bioorg Med Chem Lett. 2013 Feb 1;23(3):740-3. doi: 10.1016/j.bmcl.2012.11.085. Epub 2012 Dec 1.

PMID:
23265903
16.

Virulence factors of the Mycobacterium tuberculosis complex.

Forrellad MA, Klepp LI, Gioffré A, Sabio y García J, Morbidoni HR, de la Paz Santangelo M, Cataldi AA, Bigi F.

Virulence. 2013 Jan 1;4(1):3-66. doi: 10.4161/viru.22329. Epub 2012 Oct 17. Review.

17.

A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone.

Grzegorzewicz AE, Korduláková J, Jones V, Born SE, Belardinelli JM, Vaquié A, Gundi VA, Madacki J, Slama N, Laval F, Vaubourgeix J, Crew RM, Gicquel B, Daffé M, Morbidoni HR, Brennan PJ, Quémard A, McNeil MR, Jackson M.

J Biol Chem. 2012 Nov 9;287(46):38434-41. doi: 10.1074/jbc.M112.400994. Epub 2012 Sep 21.

18.

[The nanotech, the "Mano" and the clinical microbiology].

Morbidoni HR, Jar AM.

Rev Argent Microbiol. 2012 Apr-Jun;44(2):63-4. Spanish. No abstract available.

PMID:
22997761
19.
20.

Impact of the deletion of the six mce operons in Mycobacterium smegmatis.

Klepp LI, Forrellad MA, Osella AV, Blanco FC, Stella EJ, Bianco MV, Santangelo Mde L, Sassetti C, Jackson M, Cataldi AA, Bigi F, Morbidoni HR.

Microbes Infect. 2012 Jul;14(7-8):590-9. doi: 10.1016/j.micinf.2012.01.007. Epub 2012 Feb 8.

21.

Targeting tuberculosis through a small focused library of 1,2,3-triazoles.

Labadie GR, de la Iglesia A, Morbidoni HR.

Mol Divers. 2011 Nov;15(4):1017-24. doi: 10.1007/s11030-011-9319-0. Epub 2011 Jun 2.

PMID:
21633789
22.

[The moral of Tartuffe?].

Morbidoni HR, Leotta GA.

Rev Argent Microbiol. 2010 Apr-Jun;42(2):85-6. doi: 10.1590/S0325-75412010000200002. Spanish. No abstract available.

PMID:
20589325
23.

[Exchange of scientific information through scientific meetings: close to our friend's hearts, far away from the purse of the State].

Morbidoni HR.

Rev Argent Microbiol. 2009 Oct-Dec;41(4):203-6. Spanish. No abstract available.

PMID:
20085181
24.

Comparison of the performance of two mycobacteriophage D29-based protocols for fluoroquinolone susceptibility testing in Mycobacterium tuberculosis.

Stella EJ, de la Iglesia AI, Morbidoni HR.

J Microbiol Methods. 2009 Dec;79(3):371-3. doi: 10.1016/j.mimet.2009.10.006. Epub 2009 Oct 19.

PMID:
19846046
25.

ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria.

Kurth DG, Gago GM, de la Iglesia A, Bazet Lyonnet B, Lin TW, Morbidoni HR, Tsai SC, Gramajo H.

Microbiology. 2009 Aug;155(Pt 8):2664-75. doi: 10.1099/mic.0.027714-0. Epub 2009 May 7.

26.

Mycobacteriophages as versatile tools for genetic manipulation of mycobacteria and development of simple methods for diagnosis of mycobacterial diseases.

Stella EJ, de la Iglesia AI, Morbidoni HR.

Rev Argent Microbiol. 2009 Jan-Mar;41(1):45-55. Review.

PMID:
19391526
27.

[Vicious circle vs. virtuous circle: how to keep Revista Argentina de Microbiología in the Science Citation Index Expanded].

Morbidoni HR.

Rev Argent Microbiol. 2009 Jan-Mar;41(1):1-3. Spanish. No abstract available.

PMID:
19391517
28.

Comparison of the performances of two in-house rapid methods for antitubercular drug susceptibility testing.

de la Iglesia AI, Stella EJ, Morbidoni HR.

Antimicrob Agents Chemother. 2009 Feb;53(2):808-10. doi: 10.1128/AAC.00960-08. Epub 2008 Nov 17.

29.

Synthesis and in vitro antimycobacterial activity of 3-substituted 5-hydroxy-5-trifluoro[chloro]methyl-4,5-dihydro-1H-1-(isonicotinoyl) pyrazoles.

Almeida da Silva PE, Ramos DF, Bonacorso HG, de la Iglesia AI, Oliveira MR, Coelho T, Navarini J, Morbidoni HR, Zanatta N, Martins MA.

Int J Antimicrob Agents. 2008 Aug;32(2):139-44. doi: 10.1016/j.ijantimicag.2008.03.019. Epub 2008 Jun 20.

PMID:
18571384
30.

[Mechanisms of action of and resistance to rifampicin and isoniazid in Mycobacterium tuberculosis: new information on old friends].

De La Iglesia AI, Morbidoni HR.

Rev Argent Microbiol. 2006 Apr-Jun;38(2):97-109. Review. Spanish.

PMID:
17037259
31.

Dual inhibition of mycobacterial fatty acid biosynthesis and degradation by 2-alkynoic acids.

Morbidoni HR, Vilchèze C, Kremer L, Bittman R, Sacchettini JC, Jacobs WR Jr.

Chem Biol. 2006 Mar;13(3):297-307.

32.
33.

Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.

Kremer L, Dover LG, Morbidoni HR, Vilchèze C, Maughan WN, Baulard A, Tu SC, Honoré N, Deretic V, Sacchettini JC, Locht C, Jacobs WR Jr, Besra GS.

J Biol Chem. 2003 Jun 6;278(23):20547-54. Epub 2003 Mar 24.

34.

Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data.

Kuo MR, Morbidoni HR, Alland D, Sneddon SF, Gourlie BB, Staveski MM, Leonard M, Gregory JS, Janjigian AD, Yee C, Musser JM, Kreiswirth B, Iwamoto H, Perozzo R, Jacobs WR Jr, Sacchettini JC, Fidock DA.

J Biol Chem. 2003 Jun 6;278(23):20851-9. Epub 2003 Feb 26.

35.
36.

Bacillus subtilis acyl carrier protein is encoded in a cluster of lipid biosynthesis genes.

Morbidoni HR, de Mendoza D, Cronan JE Jr.

J Bacteriol. 1996 Aug;178(16):4794-800.

37.

Synthesis of sn-glycerol 3-phosphate, a key precursor of membrane lipids, in Bacillus subtilis.

Morbidoni HR, de Mendoza D, Cronan JE Jr.

J Bacteriol. 1995 Oct;177(20):5899-905.

38.

Isolation and characterization of Bacillus subtilis mutants blocked in the synthesis of pantothenic acid.

Baigori M, Grau R, Morbidoni HR, de Mendoza D.

J Bacteriol. 1991 Jul;173(13):4240-2.

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